Renal nerve ablation: Emerging role in therapeutics

Blood Pressure

Volumn 20, Issue 5, 2011, Pages 253-255

  Oparil, Suzanne ^a   Narkiewicz, Krzysztof ^b   Kjeldsen, Sverre ^c   Hedner, Thomas ^d  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b MEDICAL UNIVERSITY OF GDANSK   (Poland)

^c UNIVERSITY OF OSLO   (Norway)

^d UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIHYPERTENSIVE AGENT; C PEPTIDE; GLUCOSE; INSULIN; RENIN;

ABLATION THERAPY; BLOOD PRESSURE; DENERVATION; EDITORIAL; GLOMERULUS FILTRATION; HUMAN; HYPERINSULINEMIA; HYPERTENSION; INSULIN RESISTANCE; INSULIN SENSITIVITY; KIDNEY BLOOD FLOW; KIDNEY NERVE; METABOLIC SYNDROME X; MICROALBUMINURIA; NEUROGRAPHY; OVARY POLYCYSTIC DISEASE; PRESSORECEPTOR REFLEX; PRIORITY JOURNAL; RADIOFREQUENCY ABLATION; RENAL NERVE ABLATION; SYMPATHECTOMY; SYMPATHETIC NERVE;

ABLATION TECHNIQUES; BLOOD PRESSURE; GANGLIA, SYMPATHETIC; HUMANS; HYPERTENSION; KIDNEY; SYMPATHECTOMY;

EID: 80053073786     PISSN: 08037051     EISSN: 16511999     Source Type: Journal    
DOI: 10.3109/08037051.2011.613296     Document Type: Editorial

References (26)

1. DiBona GF. Physiology in perspective: The wisdom of the body. Neural control of the kidney. Am J Physiol Regul Integr Comp Physiol. 2005;289:R633-R641.
2. Schlaich M, Sobotka P, Krum H, Whitbourn R, Walton A, Esler MD. Renal denervation as a therapeutic approach for hypertension: Novel implications for an old concept. Hypertension. 2009;54:1195-1201.
3. Campese VM, Kogosov E. Renal afferent denervation prevents hypertension in rats with chronic renal failure. Hypertension. 1995;25:878-882.
4. Winternitz SR, Katholi RE, Oparil S. Role of the renal sympathetic nerves in the development and maintenance of hypertension in the spontaneously hypertensive rat. J Clin Invest. 1980;66:971-978. (Pubitemid 11233797)
5. DiBona GF, Kopp UC. Neural control of renal function. Physiol Rev. 1997;77:75-197. (Pubitemid 27069290)
6. Allen EV and Adson AE. The treatment of hypertension: Medical versus surgical. Ann Int Med. 1940;14:288-307.
7. Peet MM. Hypertension and its surgical treatment by bilateral supradiaphragmatic splanchnicectomy. Am J Surg. 1948; 75:48-68.
8. Smithwick RH. Surgery of the autonomic nervous system. N Engl J Med. 1947;236:662-669.
9. Smithwick RH, Thompson JE. Splanchnicectomy for essential hypertension; results in 1,266 cases. JAMA. 1953;152: 1501-1504.
10. Oparil S. Can catheter-based renal denervation be used safely and effectively to substantially reduce blood pressure in treatment-resistant hypertensive patients. Curr Cardiol Rep. 2011; in press.
11. Krum H, Schlaich M, Whitbourn R, Sobotka PA, Bartus K, Kapelak B, et al. Catheter-based renal sympathetic denervation for resistant hypertension: A multicentre safety and proofof-principle cohort study. Lancet. 2009;373:1275-1281.
12. Schlaich MP, Sobotka PA, Krum H, Lambert E, Esler MD. Renal sympathetic-nerve ablation for uncontrolled hypertension. N Engl J Med. 2009;361:932-934.
13. Esler MD, Krum H, Sobotka PA, Schlaich MP, Schmieder RE, B öhm M, Symplicity HTN-2 Investigators. Renal sympathetic denervation in patients with treatment-resistant hypertension (The Symplicity HTN-2 Trial): A randomised controlled trial. Lancet. 2010;376:1903-1909.
14. Symplicity HTN-1 Investigators. Catheter-based renal sympathetic denervation for resistant hypertension: Durability of blood pressure reduction out to 24 months. Hypertension. 2011;57:911-917.
15. Alexander CJ, Tangchitnob EP, Lepor NE. Polycystic ovary syndrome: A major unrecognized cardiovascular risk factor in women. Rev Obstet Gynecol. 2009;2:232-239.
16. Teede H, Deeks A, Moran L. Polycystic ovary syndrome: A complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan. BMC Med. 2010;8:41.
17. Sverrisdòttir YB, Mogren T, Kataoka J, Janson PO, Stener-Victorin E. Is polycystic ovary syndrome associated with high sympathetic nerve activity and size at birth? Am J Physiol Endocrinol Metab. 2008;294:E576-E581. (Pubitemid 351355228)
18. Masuo K, Mikami H, Ogihara T, Tuck ML. Sympathetic nerve hyperactivity precedes hyperinsulinemia and blood pressure elevation in a young, nonobese Japanese population. Am J Hypertens. 1997;10:77-83. (Pubitemid 27038975)
19. Mancia G, Bousquet P, Elghozi JL, Esler M, Grassi G, Julius S, et al. The sympathetic nervous system and the metabolic syndrome. J Hypertens. 2007;25:909-920. (Pubitemid 46573105)
20. Lara HE, Ferruz JL, Luza S, Bustamante DA, Borges Y, Ojeda SR. Activation of ovarian sympathetic nerves in polycystic ovary syndrome. Endocrinology. 1993;133:2690-2695. (Pubitemid 24000721)
21. Barria A, Leyton V, Ojeda SR, Lara HE. Ovarian steroidal response to gonadotropins and beta-adrenergic stimulation is enhanced in polycystic ovary syndrome: Role of sympathetic innervation. Endocrinology. 1993;133:2696-2703. (Pubitemid 24000722)
22. Schlaich MP, Straznickya N, Grimaa M, Ika-Saria C, Dawooda T, Mahfoudb F, et al. Renal denervation: A potential new treatment modality for polycystic ovary syndrome? J Hypertens. 2011;29:991-996.
23. Mahfoud F, Schlaich M, Kindermann I, Ukena C, Cremers B, Brandt MC, et al. Effect of renal sympathetic denervation on glucose metabolism in patients with resistant hypertension: A pilot study. Circulation. 2011;123: 1940-1946.
24. Esler M. The. 2009 Carl Ludwig Lecture: Pathophysiology of the human sympathetic nervous system in cardiovascular diseases: The transition from mechanisms to medical management. J Appl Physiol. 2010;108:227-237.
25. Krum H, Sobotka P, Mahfoud F, Böhm M, Esler M, Schlaich M. Device-based antihypertensive therapy: Therapeutic modulation of the autonomic nervous system. Circulation. 2011; 123:209-215.
26. Sobotka PA, Mahfoud F, Schlaich MP, Hoppe UC, Böh m M, Krum H. Sympatho-renal axis in chronic disease. Clin Res Cardiol. 2011; Published online June 19. DOI: 10.1007/ s00392-011-0335-y