Gastroprotective activity of Swietenia mahagoni seed extract on ethanol-induced gastric mucosal injury in rats

World Academy of Science, Engineering and Technology

Volumn 43, Issue , 2010, Pages 883-887

  Alrdahe, Salma Saleh ^a   Abdulla, Mahmood Ameen ^a   Razak, Shaharudin Abul ^a   Kadir, Farkaad Abdul ^a   Hassandarvish, Pouya ^a  

^a UNIVERSITY OF MALAYA   (Malaysia)

Author keywords

Cytoprotection; Gastric ulcer; Histology; Swietenia mahagoni seed

Indexed keywords

ABSOLUTE ETHANOL; ACUTE TOXICITY; CARBOXY-METHYL CELLULOSE; CYTOPROTECTION; GASTRIC MUCOSA; GASTRIC MUCOSAL INJURY; GASTRIC ULCERS; LEUCOCYTES; OMEPRAZOLE; ORAL ADMINISTRATION; PRE-TREATMENT;

CELLULOSE; CHEMICAL COMPOUNDS; ETHANOL; HISTOLOGY; PLANT EXTRACTS; RATS;

DISEASES;

EID: 80053072001     PISSN: 2010376X     EISSN: 20103778     Source Type: Journal    
DOI: None     Document Type: Article

References (39)

1. Mulholland, D., B. Parel, and P. Coombes. The chemistry of the Meliaceae and Ptaeroxylaceae of southern and eastern Africa and Madagascar. Current Organic Chemistry, 2000, 4(10): p. 1011-1054.
2. Munoz, V., Sauvain, M., Bourdy, G., Callapa, J., Rojas, I., Vargas, L., Tae A., and Deharo, E. The search for natural bioactive compounds through a multidisciplinary approach in Bolivia. Part II. Antimalarial activity of some plants used by Mosetene Indians. Journal of ethnopharmacology, 2000, 69(2): 139-155.
3. Maiti, A., S. Dewanjee, and S. Mandal. In vivo evaluation of antidiarrhoeal activity of the seed of Swietenia macrophylla King (Meliaceae). Tropical Journal of Pharmaceutical Research, 2007, 6(2): 711-716.
4. Majid, M., Rahman, I.M.M.; Shipar, M.A.H.; Uddin, M.H.; Chowdhury, R. Physico-chemical characterization, antimicrobial activity and toxicity analysis of Swietenia mahagoni seed oil. International Journal of Agriculture and Biology (Pakistan), 2004, 6(2),350-354.
5. Govindachari, T.; Suresh G.; Banumathy B.; Masilamani S.; Gopalakrishnan G.; KrishnaKumari G.N. Antifungal activity of some B, D-seco limonoids from two meliaceous plants. Journal of Chemical Ecology,1999, 25(4): 923-933.
6. Li, D., Chen, J.H., Chen, Q., Li., G. W, Chen, J., Yue, J.M., Chen, M.L., Wang, X.P., Shen, J.H., Shen, X., Jiang, H.L. Swietenia mahagony extract shows agonistic activity to PPAR and gives ameliorative effects on diabetic db/db mice. Acta Pharmacologica Sinica, 2005, 26(2): 220-222.
7. Nagalakshmi, M.; Thangadurai, D.; Muralidara, D.; Pullaiah, R.T. Phytochemical and antimicrobial study of Chukrasia tabularis leaves. Fitoterapia, 2001, 72(1): 62-64.
8. Bacsal, K.; Havez, L.; Diaz, I.; Espina, S.; Javillo, J.; Manzanilla, H.; Motalban, J.; Panganiban, C.; Ro driguez, A.; Sumpaico, C.; Talip, B.; Yap, S. The effect of Switenia mahogany (mahogany) seed extract on indomethacin-induced gastric ulcers in female Sprague-Dawley rats. Acta Medica Philippina, 1997, 3:127-139.
9. Sahgal, G., Ramanathan S, Sasidharan S, Mordi MN, Ismail S, Mansor SM. In Vitro Antioxidant and Xanthine Oxidase Inhibitory Activities of Methanolic Swietenia mahagoni Seed Extracts. Molecules (Basel, Switzerland), 2009, 14(11): 4476-85.
10. Sahgal, G., Ramanathan, S., Sasidharan, S., Mordi, M.N., Ismail, S. and Mansor, S.M. Phytochemical and antimicrobial activity of Swietenia mahagoni crude methanolic seed extract. Tropical Biomedicine,2009, 26(3): 274-279.
11. Li, X., Andersson, T.B., Ahlstom, M., Weidolf, L. Comparison of inhibitory effects of the proton pump-inhibiting drugs omeprazole, esomeprazole, lansoprazole, pantoprazole, and rabeprazole on human cytochrome P450 activities. Drug metabolism and disposition, 2004, 32(8): 821-827.
12. Satoh, H., Inatomi, N., Nagaya, H., Ianda, I., Nohara, A., Nakamura, H. Antisecretory and antiulcer activities of a novel proton pump inhibitor AG-1749 in dogs and rats. Journal of Pharmacology and Experimental Therapeutics, 1989, 248(2): 806-815.
13. Nagaya, H., Inatomi, N., Ohara, A., Satoh, H. (1991). Effects of the enantiomers of lansoprazole (AG-1749) on (H++ K+)-ATPase activity in canine gastric microsomes and acid formation in isolated canine parietal cells. Biochemical pharmacology, 42(10): 1875-1878.
14. Pedernera, A.M., Guardia, T., Caleron, C.G., Rotelli, A.F., de la Rocha, N.F., di Genaro, S., Pelze, L.F. Anti-ulcerogenic and anti-inflammatory activity of the methanolic extract of Larrea divaricata Cav. in rat. Journal of ethnopharmacology, 2006, 105(3): 415-420.
15. De Pasquale, R., Germano, M.P., Keita, A., Sanogo, R., Lauk, L. Antiulcer activity of Pteleopsis suberosa. Journal of ethnopharmacology, 1995, 47(1): 55-58.
16. Bergmeyer, H. and M. Horder. IFCC methods for the measurement of catalytic concentration of enzymes, Part 3. IFCC method for alanine aminotransferase. J Clin Chem Clin Biochem, 1980, 18: 521-534.
17. Tietz, N.W., Rinker, A.D., Shaw, L.M. (1983). IFCC methods for the measurement of catalytic concentration of enzymes, Part 5. IFCC method for alkaline phosphatase. J Clin Chem Clin Biochem, 1983, 21(11): 731-748.
18. Garg, G.P., Nigam, S.K., Ogle, C.W. The gastric antiulcer effects of the leaves of the neem tree. Planta medica, 1993, 59: 215-215.
19. Hollander, D., Taranawski, A., Krause, W.J., Gergely, H. Protective effect of sucralfate against alcohol-induced gastric mucosal injury in the rat. Macroscopic, histologic, ultrastructural, and functional time sequence analysis. Gastroenterology, 1985, 88(1 Pt 2): 366-374.
20. Paiva, L.A. F, Rao, V.S.N., Gramosa, N.V., Silveira, F.R. Gastroprotective effect of Copaifera langsdorffii oleo-resin on experimental gastric ulcer models in rats. Journal of ethnopharmacology, 1998, 62(1): 73-78.
21. Kauffman, G. L., Grossman, M. I. Prostaglandin and cimetidine inhibit the formation of ulcers produced by parenteral salicylates. Gastroenterology, 1978, 75(6): 1099-2102.
22. Njar V. C. O., Adesanwo J. K., Raji Y. Methyl Angolenate: The Antiulcer Agent from the Stem Bark of Entandrophragma angolense. Planta medica, 1995, 61: 91-92.
23. Piper, D.W. and Stiel, D. (1986). Pathogenesis of chronic peptic ulcer, current thinking and clinical implications. Med Prog, 2: 7-10.
24. Baron, T.H., Langman, M.T.S. and Wastell, C. Stomach and duodenum. Recent advances in gastroenterology. Churchill Livingstone, Edinburgh, 1980, p. 23-86.
25. Szabo, S., Kusstatscher, S, Sakoulas, G, Sandor, Z, Vincze, A & Jadus, M. Growth factors: new 'endogenous drugs' for ulcer healing. Scandinavian Journal of Gastroenterology, 1995, 30: p. 15-18.
26. Marhuenda, E., Martin, M.J. and Alarcon de la Lastra, C. Antiulcerogenic activity of aescine in different experimental models. Phytotherapy Research, 2006, 7(1): 13-16.
27. Mutoh, H., Hiraishi, H., Ota, S., Ivey, K.J. Terano, A. Sugimoto, T. Role of oxygen radicals in ethanol-induced damage to cultured gastric mucosal cells. American Journal of Physiology-Gastrointestinal and Liver Physiology, 1990, 258(4): G603-G609.
28. Trivedi, N.P., Rawal, U.M. Hepatoprotective and antioxidant property of Andrographis paniculata (Nees) in BHC induced liver damage in mice. Indian Journal of Experimental Biology, 2001, 39(1): 41-46.
29. Ligumsky, M., Sestieri, M., Okon, F., Ginsburg, I. Antioxidants inhibit ethanol-induced gastric injury in the rat: role of manganese, glycine, and carotene. Scandinavian Journal of Gastroenterology, 1995, 30(9): 854-860.
30. Kobayashi, T., Ohta, Y., Yoshino, J., Nakazawa, S. Teprenone promotes the healing of acetic acid-induced chronic gastric ulcers in rats by inhibiting neutrophil infiltration and lipid peroxidation in ulcerated gastric tissues. Pharmacological Research, 2001, 43(1): 23-30.
31. Shimizu, N., Watanabe T, Arakawa T, Fujiwara Y, Higuchi K, Kuroki T. Pentoxifylline accelerates gastric ulcer healing in rats: roles of tumor necrosis factor alpha and neutrophils during the early phase of ulcer healing. Digestion, 2000, 61(3): 157-164.
32. Cheng CL, Koo MWL. Effects of Centella asiatica on ethanol induced gastric mucosal lesions in rats. Life sciences, 2000, 67(21): 2647-2653.
33. Fujita, H, Takahashi, S., Okabe, S. Mechanism by which indomethacin delays the healing of acetic acid-induced ulcers in rats. Role of neutrophil antichemotactic and chemotactic activities. Journal of physiology and pharmacology: an official journal of the Polish Physiological Society, 1998, 49(1): 71-82.
34. Suzuki, Y., Ishihara M, Ito M. Anti-ulcer effects of antioxidants, quercetin,-tocopherol, nifedipine and tetracycline in rats. The Japanese Journal of Pharmacology, 1998, 78(4): p. 435-441.
35. Zimmerman, J.J. Ciesielski, W., Lewandoski, J. Neutrophil-mediated phospholipid peroxidation assessed by gas chromatography-mass spectroscopy. American Journal of Physiology-Cell Physiology, 1997, 273(2): C653-661.
36. Garrick, T., Buack, S., Bass, P. Gastric motility is a major factor in cold restraint-induced lesion formation in rats. American Journal of Physiology-Gastrointestinal and Liver Physiology, 1986, 250(2):191-199.
37. Takeuchi, K., Nishiwakki, K., Okabe, S. Effects of dopamine on gastric mucosal lesions induced by ethanol in rats. Digestive Diseases and Sciences, 1988, 33(12): 1560-1568.
38. Takeuch, K. and Nobuhara, Y. Inhibition of gastric motor activity by 16, 16-dimethyl prostaglandin E 2. Digestive Diseases and Sciences, 1985, 30(12): 1181-1188.
39. Mersereau, A.W. and Hinchey, E.J. Role of gastric mucosal folds in formation of focal ulcers in the rat. Surgery, 1982, 91(2):150-155.