메뉴 건너뛰기




Volumn 108, Issue 37, 2011, Pages 15426-15431

Mapping the receptor site for α-scorpion toxins on a Na + channel voltage sensor

Author keywords

Mutagenesis; Voltage gated sodium channel

Indexed keywords

ALPHA SCORPION TOXIN; AMINO ACID; SCORPION VENOM; SODIUM CHANNEL NAV1.2; UNCLASSIFIED DRUG;

EID: 80053064950     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1112320108     Document Type: Article
Times cited : (111)

References (44)
  • 1
    • 35649001607 scopus 로고
    • A quantitative description of membrane current and its application to conduction and excitation in nerve
    • Hodgkin AL, Huxley AF (1952) A quantitative description of membrane current and its application to conduction and excitation in nerve. J Physiol 117:500-544.
    • (1952) J Physiol , vol.117 , pp. 500-544
    • Hodgkin, A.L.1    Huxley, A.F.2
  • 2
    • 0033694833 scopus 로고    scopus 로고
    • From ionic currents to molecular mechanisms: The structure and function of voltage-gated sodium channels
    • Catterall WA (2000) From ionic currents to molecular mechanisms: The structure and function of voltage-gated sodium channels. Neuron 26:13-25.
    • (2000) Neuron , vol.26 , pp. 13-25
    • Catterall, W.A.1
  • 3
    • 0033731909 scopus 로고    scopus 로고
    • Molecular mechanisms of neurotoxin action on voltage-gated sodium channels
    • Cestèle S, Catterall WA (2000) Molecular mechanisms of neurotoxin action on voltage-gated sodium channels. Biochimie 82:883-892.
    • (2000) Biochimie , vol.82 , pp. 883-892
    • Cestèle, S.1    Catterall, W.A.2
  • 5
    • 77950515381 scopus 로고    scopus 로고
    • Targeting voltage sensors in sodium channels with spider toxins
    • Bosmans F, Swartz KJ (2010) Targeting voltage sensors in sodium channels with spider toxins. Trends Pharmacol Sci 31:175-182.
    • (2010) Trends Pharmacol Sci , vol.31 , pp. 175-182
    • Bosmans, F.1    Swartz, K.J.2
  • 6
    • 0019596088 scopus 로고
    • Sodium channels and gating currents
    • Armstrong CM (1981) Sodium channels and gating currents. Physiol Rev 61:644-683.
    • (1981) Physiol Rev , vol.61 , pp. 644-683
    • Armstrong, C.M.1
  • 7
    • 77956996917 scopus 로고    scopus 로고
    • Ion channel voltage sensors: Structure, function, and pathophysiology
    • Catterall WA (2010) Ion channel voltage sensors: Structure, function, and pathophysiology. Neuron 67:915-928.
    • (2010) Neuron , vol.67 , pp. 915-928
    • Catterall, W.A.1
  • 8
    • 0023784649 scopus 로고
    • Identification of an intracellular peptide segment involved in sodium channel inactivation
    • Vassilev PM, Scheuer T, Catterall WA (1988) Identification of an intracellular peptide segment involved in sodium channel inactivation. Science 241:1658-1661.
    • (1988) Science , vol.241 , pp. 1658-1661
    • Vassilev, P.M.1    Scheuer, T.2    Catterall, W.A.3
  • 9
  • 10
  • 11
    • 0028233375 scopus 로고
    • Crystal structure of toxin II from the scorpion Androctonus australis Hector refined at 1.3 Å resolution
    • Housset D, Habersetzer-Rochat C, Astier JP, Fontecilla-Camps JC (1994) Crystal structure of toxin II from the scorpion Androctonus australis Hector refined at 1.3 Å resolution. J Mol Biol 238:88-103.
    • (1994) J Mol Biol , vol.238 , pp. 88-103
    • Housset, D.1    Habersetzer-Rochat, C.2    Astier, J.P.3    Fontecilla-Camps, J.C.4
  • 14
    • 0030037704 scopus 로고    scopus 로고
    • + channel alpha subunit
    • DOI 10.1074/jbc.271.27.15950
    • Rogers JC, Qu Y, Tanada TN, Scheuer T, Catterall WA (1996) Molecular determinants of high affinity binding of alpha-scorpion toxin and sea anemone toxin in the S3-S4 extracellular loop in domain IV of the Na+ channel alpha subunit. J Biol Chem 271:15950-15962. (Pubitemid 26236206)
    • (1996) Journal of Biological Chemistry , vol.271 , Issue.27 , pp. 15950-15962
    • Rogers, J.C.1    Qu, Y.2    Tanada, T.N.3    Scheuer, T.4    Catterall, W.A.5
  • 15
    • 56249091754 scopus 로고    scopus 로고
    • Deconstructing voltage sensor function and pharmacology in sodium channels
    • Bosmans F, Martin-Eauclaire MF, Swartz KJ (2008) Deconstructing voltage sensor function and pharmacology in sodium channels. Nature 456:202-208.
    • (2008) Nature , vol.456 , pp. 202-208
    • Bosmans, F.1    Martin-Eauclaire, M.F.2    Swartz, K.J.3
  • 16
    • 0036122207 scopus 로고    scopus 로고
    • Variations in receptor site-3 on rat brain and insect sodium channels highlighted by binding of a funnel-web spider delta-atracotoxin
    • DOI 10.1046/j.1432-1033.2002.02799.x
    • Gilles N, et al. (2002) Variations in receptor site-3 on rat brain and insect sodium channels highlighted by binding of a funnel-web spider delta-atracotoxin. Eur J Biochem 269:1500-1510. (Pubitemid 34227091)
    • (2002) European Journal of Biochemistry , vol.269 , Issue.5 , pp. 1500-1510
    • Gilles, N.1    Harrison, G.2    Karbat, I.3    Gurevitz, M.4    Nicholson, G.M.5    Gordon, D.6
  • 17
    • 0017662903 scopus 로고
    • + ionophore. Studies with a toxin derivative prepared by lactoperoxidase-catalyzed iodination
    • + ionophore. Studies with a toxin derivative prepared by lactoperoxidase-catalyzed iodination. J Biol Chem 252:8660-8668.
    • (1977) J Biol Chem , vol.252 , pp. 8660-8668
    • Catterall, W.A.1
  • 18
    • 0018582440 scopus 로고
    • Binding of scorpion toxin to receptor sites associated with sodium channels in frog muscle. Correlation of voltage-dependent binding with activation
    • Catterall WA (1979) Binding of scorpion toxin to receptor sites associated with sodium channels in frog muscle. Correlation of voltage-dependent binding with activation. J Gen Physiol 74:375-391.
    • (1979) J Gen Physiol , vol.74 , pp. 375-391
    • Catterall, W.A.1
  • 20
    • 0033767401 scopus 로고    scopus 로고
    • A hot spot for the interaction of gating modifier toxins with voltage-dependent ion channels
    • Winterfield JR, Swartz KJ (2000) A hot spot for the interaction of gating modifier toxins with voltage-dependent ion channels. J Gen Physiol 116:637-644.
    • (2000) J Gen Physiol , vol.116 , pp. 637-644
    • Winterfield, J.R.1    Swartz, K.J.2
  • 22
    • 0034130607 scopus 로고    scopus 로고
    • + channel
    • DOI 10.1085/jgp.115.6.673
    • Li-Smerin Y, Swartz KJ (2000) Localization and molecular determinants of the Hanatoxin receptors on the voltage-sensing domains of a K+ channel. J Gen Physiol 115:673-684. (Pubitemid 30396076)
    • (2000) Journal of General Physiology , vol.115 , Issue.6 , pp. 673-684
    • Li-Smerin, Y.1    Swartz, K.J.2
  • 23
    • 0037306968 scopus 로고    scopus 로고
    • The selectivity of scorpion alpha-toxins for sodium channel subtypes is determined by subtle variations at the interacting surface
    • DOI 10.1016/S0041-0101(02)00294-5, PII S0041010102002945
    • Gordon D, Gurevitz M (2003) The selectivity of scorpion alpha-toxins for sodium channel subtypes is determined by subtle variations at the interacting surface. Toxicon 41:125-128. (Pubitemid 36144178)
    • (2003) Toxicon , vol.41 , Issue.2 , pp. 125-128
    • Gordon, D.1    Gurevitz, M.2
  • 25
    • 0036460766 scopus 로고    scopus 로고
    • Differential sensitivity of sodium channels from the central and peripheral nervous system to the scorpion toxins Lqh-2 and Lqh-3
    • DOI 10.1046/j.1460-9568.2002.02142.x
    • Chen H, et al. (2002) Differential sensitivity of sodium channels from the central and peripheral nervous system to the scorpion toxins Lqh-2 and Lqh-3. Eur J Neurosci 16:767-770. (Pubitemid 35471847)
    • (2002) European Journal of Neuroscience , vol.16 , Issue.4 , pp. 767-770
    • Chen, H.1    Lu, S.2    Leipold, E.3    Gordon, D.4    Hansel, A.5    Heinemann, S.H.6
  • 26
    • 1342287128 scopus 로고    scopus 로고
    • Combinatorial Interaction of Scorpion Toxins Lqh-2, Lqh-3, and LqhαIT with Sodium Channel Receptor Sites-3
    • DOI 10.1124/mol.65.3.685
    • Leipold E, Lu S, Gordon D, Hansel A, Heinemann SH (2004) Combinatorial interaction of scorpion toxins Lqh-2, Lqh-3, and LqhαIT with sodium channel receptor sites-3. Mol Pharmacol 65:685-691. (Pubitemid 38264036)
    • (2004) Molecular Pharmacology , vol.65 , Issue.3 , pp. 685-691
    • Leipold, E.1    Lu, S.2    Gordon, D.3    Hansel, A.4    Heinemann, S.H.5
  • 29
    • 34548861782 scopus 로고    scopus 로고
    • Protein-Protein Docking with Backbone Flexibility
    • DOI 10.1016/j.jmb.2007.07.050, PII S0022283607010030
    • Wang C, Bradley P, Baker D (2007) Protein-protein docking with backbone flexibility. J Mol Biol 373:503-519. (Pubitemid 47445567)
    • (2007) Journal of Molecular Biology , vol.373 , Issue.2 , pp. 503-519
    • Wang, C.1    Bradley, P.2    Baker, D.3
  • 32
    • 34748848687 scopus 로고    scopus 로고
    • + channel
    • + channel. Neuron 56:124-140.
    • (2007) Neuron , vol.56 , pp. 124-140
    • Pathak, M.M.1
  • 34
    • 33745228127 scopus 로고    scopus 로고
    • Subtype specificity of scorpion beta-toxin Tz1 interaction with voltage-gated sodium channels is determined by the pore loop of domain 3
    • Leipold E, Hansel A, Borges A, Heinemann SH (2006) Subtype specificity of scorpion beta-toxin Tz1 interaction with voltage-gated sodium channels is determined by the pore loop of domain 3. Mol Pharmacol 70:340-347.
    • (2006) Mol Pharmacol , vol.70 , pp. 340-347
    • Leipold, E.1    Hansel, A.2    Borges, A.3    Heinemann, S.H.4
  • 35
    • 0037198626 scopus 로고    scopus 로고
    • Crystal structure and mechanism of a calcium-gated potassium channel
    • DOI 10.1038/417515a
    • Jiang Y, et al. (2002) Crystal structure and mechanism of a calcium-gated potassium channel. Nature 417:515-522. (Pubitemid 34595912)
    • (2002) Nature , vol.417 , Issue.6888 , pp. 515-522
    • Jiang, Y.1    Lee, A.2    Chen, J.3    Cadene, M.4    Chait, B.T.5    MacKinnon, R.6
  • 36
    • 23244456428 scopus 로고    scopus 로고
    • + channel
    • DOI 10.1126/science.1116269
    • Long SB, Campbell EB, Mackinnon R (2005) Crystal structure of a mammalian voltage-dependent Shaker family K+ channel. Science 309:897-903. (Pubitemid 41099919)
    • (2005) Science , vol.309 , Issue.5736 , pp. 897-903
    • Long, S.B.1    Campbell, E.B.2    MacKinnon, R.3
  • 37
    • 23244441222 scopus 로고    scopus 로고
    • Voltage sensor of Kv1.2: Structural basis of electromechanical coupling
    • DOI 10.1126/science.1116270
    • Long SB, Campbell EB, Mackinnon R (2005) Voltage sensor of Kv1.2: Structural basis of electromechanical coupling. Science 309:903-908. (Pubitemid 41099920)
    • (2005) Science , vol.309 , Issue.5736 , pp. 903-908
    • Long, S.B.1    Campbell, E.B.2    MacKinnon, R.3
  • 40
    • 68949137013 scopus 로고    scopus 로고
    • Molecular requirements for recognition of brain voltage-gated sodium channels by scorpion alpha-toxins
    • Kahn R, et al. (2009) Molecular requirements for recognition of brain voltage-gated sodium channels by scorpion alpha-toxins. J Biol Chem 284:20684-20691.
    • (2009) J Biol Chem , vol.284 , pp. 20684-20691
    • Kahn, R.1
  • 43
    • 4444221565 scopus 로고    scopus 로고
    • UCSF Chimera - A visualization system for exploratory research and analysis
    • Pettersen EF, et al. (2004) UCSF Chimera - A visualization system for exploratory research and analysis. J Comput Chem 25:1605-1612.
    • (2004) J Comput Chem , vol.25 , pp. 1605-1612
    • Pettersen, E.F.1
  • 44
    • 35548936575 scopus 로고    scopus 로고
    • V1.2 channels by Fyn tyrosine kinase
    • DOI 10.1523/JNEUROSCI.1743-07.2007
    • Beacham D, Ahn M, Catterall WA, Scheuer T (2007) Sites and molecular mechanisms of modulation of Nav1.2 channels by Fyn tyrosine kinase. J Neurosci 27:11543-11551. (Pubitemid 350006890)
    • (2007) Journal of Neuroscience , vol.27 , Issue.43 , pp. 11543-11551
    • Beacham, D.1    Ahn, M.2    Catterall, W.A.3    Scheuer, T.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.