메뉴 건너뛰기




Volumn 26, Issue 5, 2011, Pages 343-346

Tapentadol for Multimodal Pain Management

Author keywords

[No Author keywords available]

Indexed keywords

3-(3-DIMETHYLAMINO-1-ETHYL-2-METHYLPROPYL)PHENOL; ANALGESIC AGENT; MU OPIATE RECEPTOR; PHENOL DERIVATIVE; TAPENTADOL;

EID: 80053064473     PISSN: 10899472     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jopan.2011.06.001     Document Type: Article
Times cited : (6)

References (34)
  • 1
    • 79251517432 scopus 로고    scopus 로고
    • Neurophysiology of pain and analgesia and the pathophysiology of neuropathic pain
    • Mosby/Elsevier, St Louis, MO, C. Pasero, M. McCaffery (Eds.)
    • Pasero C., Portenoy R.K. Neurophysiology of pain and analgesia and the pathophysiology of neuropathic pain. Pain Assessment and Pharmacologic Management 2011, 1-12. Mosby/Elsevier, St Louis, MO. C. Pasero, M. McCaffery (Eds.).
    • (2011) Pain Assessment and Pharmacologic Management , pp. 1-12
    • Pasero, C.1    Portenoy, R.K.2
  • 2
    • 50349092303 scopus 로고    scopus 로고
    • Painful diabetic neuropathy: Epidemiology, natural history, early diagnosis, and treatment options
    • Veves A., Backonja M., Malik R.A. Painful diabetic neuropathy: Epidemiology, natural history, early diagnosis, and treatment options. Pain Med 2008, 9:660-674.
    • (2008) Pain Med , vol.9 , pp. 660-674
    • Veves, A.1    Backonja, M.2    Malik, R.A.3
  • 4
    • 79953000425 scopus 로고    scopus 로고
    • Synergistic interaction between the two mechanisms of action of tapentadol in analgesia
    • Schroder W., Tzschentke T.M., Terlinden R., et al. Synergistic interaction between the two mechanisms of action of tapentadol in analgesia. J Pharmacol Exp Ther 2011, 337:312-320.
    • (2011) J Pharmacol Exp Ther , vol.337 , pp. 312-320
    • Schroder, W.1    Tzschentke, T.M.2    Terlinden, R.3
  • 5
    • 77953443660 scopus 로고    scopus 로고
    • Tapentadol immediate release: A new treatment option for acute pain management
    • Afilalo M., Stegmann J.U., Upmalis D. Tapentadol immediate release: A new treatment option for acute pain management. J Pain Res 2010, 3:1-9.
    • (2010) J Pain Res , vol.3 , pp. 1-9
    • Afilalo, M.1    Stegmann, J.U.2    Upmalis, D.3
  • 6
    • 77956057791 scopus 로고    scopus 로고
    • Tapentadol and its two mechanisms of action: Is there a new pharmacological class of centrally-acting analgesics on the horizon?
    • [editorial]
    • Kress H.G. Tapentadol and its two mechanisms of action: Is there a new pharmacological class of centrally-acting analgesics on the horizon?. Eur J Pain 2010, 14:781-783. [editorial].
    • (2010) Eur J Pain , vol.14 , pp. 781-783
    • Kress, H.G.1
  • 7
    • 36549023069 scopus 로고    scopus 로고
    • Absorption, metabolism, and excretion of 14C-labeled tapentadol HCl in healthy male subjects
    • Terlinden R., Ossig J., Fliegert F., et al. Absorption, metabolism, and excretion of 14C-labeled tapentadol HCl in healthy male subjects. Eur J Drug Metab Pharmacokinet 2007, 32:163-169.
    • (2007) Eur J Drug Metab Pharmacokinet , vol.32 , pp. 163-169
    • Terlinden, R.1    Ossig, J.2    Fliegert, F.3
  • 10
    • 84856541628 scopus 로고    scopus 로고
    • Pricara, Ortho-McNeil-Janssen, Raritan, NJ, Available at:, Accessed June 10, 2011
    • Pricara Nucynta [package insert]. Pricara, Division of Ortho McNeil Pharmaceuticals 2009, Ortho-McNeil-Janssen, Raritan, NJ, Available at:, Accessed June 10, 2011. http://www.nucynta.com/nucynta/assets/Nucynta-PI.pdf.
    • (2009) Nucynta [package insert]. Pricara, Division of Ortho McNeil Pharmaceuticals
  • 11
    • 79958201835 scopus 로고    scopus 로고
    • Comparable efficacy and superior gastrointestinal tolerability (nausea, vomiting, constipation) of tapentadol compared with oxycodone hydrochloride
    • Etropolski M., Kelly K., Okamoto A., et al. Comparable efficacy and superior gastrointestinal tolerability (nausea, vomiting, constipation) of tapentadol compared with oxycodone hydrochloride. Adv Ther 2011, 28:401-417.
    • (2011) Adv Ther , vol.28 , pp. 401-417
    • Etropolski, M.1    Kelly, K.2    Okamoto, A.3
  • 12
    • 78650621424 scopus 로고    scopus 로고
    • Cost-effectiveness analysis of tapentadol immediate release for treatment of acute pain
    • Kwong W.J., Ozer-Stillman I., Miller J.D., et al. Cost-effectiveness analysis of tapentadol immediate release for treatment of acute pain. Clin Ther 2010, 32:1768-1781.
    • (2010) Clin Ther , vol.32 , pp. 1768-1781
    • Kwong, W.J.1    Ozer-Stillman, I.2    Miller, J.D.3
  • 13
    • 2542492932 scopus 로고    scopus 로고
    • Practice guidelines for acute pain management in the perioperative setting: An updated report
    • American Society of Anesthesiologists (ASA)
    • American Society of Anesthesiologists (ASA) Practice guidelines for acute pain management in the perioperative setting: An updated report. Anesthesiology 2004, 100:1573-1581.
    • (2004) Anesthesiology , vol.100 , pp. 1573-1581
  • 15
    • 35748943212 scopus 로고    scopus 로고
    • Pharmacologic management of neuropathic pain: Evidence-based recommendations
    • Dworkin R.H., O'Connor A.B., Backonja M., et al. Pharmacologic management of neuropathic pain: Evidence-based recommendations. Pain 2007, 132:237-251.
    • (2007) Pain , vol.132 , pp. 237-251
    • Dworkin, R.H.1    O'Connor, A.B.2    Backonja, M.3
  • 16
    • 67649435616 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo-controlled phase 3 study of the relative efficacy and tolerability of tapentadol IR and oxycodone IR for acute pain
    • Daniels S., Casson E., Stegmann J.U., et al. A randomized, double-blind, placebo-controlled phase 3 study of the relative efficacy and tolerability of tapentadol IR and oxycodone IR for acute pain. Curr Med Res Opin 2009, 25:1551-1561.
    • (2009) Curr Med Res Opin , vol.25 , pp. 1551-1561
    • Daniels, S.1    Casson, E.2    Stegmann, J.U.3
  • 17
    • 62149148657 scopus 로고    scopus 로고
    • The efficacy and tolerability of multiple-dose tapentadol immediate release for the relief of acute pain following orthopedic (bunionectomy) surgery
    • Stegmann J.U., Weber H., Steup A., et al. The efficacy and tolerability of multiple-dose tapentadol immediate release for the relief of acute pain following orthopedic (bunionectomy) surgery. Curr Med Res Opin 2008, 24:1385-1396.
    • (2008) Curr Med Res Opin , vol.24 , pp. 1385-1396
    • Stegmann, J.U.1    Weber, H.2    Steup, A.3
  • 18
    • 67649378979 scopus 로고    scopus 로고
    • A randomized, double-blind, phase III study comparing multiple doses of tapentadol IR, oxycodone IR, and placebo for postoperative (bunionectomy) pain
    • Daniels S.E., Upmalis D., Okamoto A., et al. A randomized, double-blind, phase III study comparing multiple doses of tapentadol IR, oxycodone IR, and placebo for postoperative (bunionectomy) pain. Curr Med Res Opin 2009, 25:765-776.
    • (2009) Curr Med Res Opin , vol.25 , pp. 765-776
    • Daniels, S.E.1    Upmalis, D.2    Okamoto, A.3
  • 19
    • 58149308239 scopus 로고    scopus 로고
    • Single dose analgesic efficacy of tapentadol in postsurgical dental pain: The results of a randomized, double-blind, placebo-controlled study
    • Kleinert R., Lange C., Steup A., et al. Single dose analgesic efficacy of tapentadol in postsurgical dental pain: The results of a randomized, double-blind, placebo-controlled study. Anesth Analg 2008, 107:2048-2055.
    • (2008) Anesth Analg , vol.107 , pp. 2048-2055
    • Kleinert, R.1    Lange, C.2    Steup, A.3
  • 21
    • 77953577261 scopus 로고    scopus 로고
    • Review of the effect of opioid-related side effects on the undertreatment of moderate to severe chronic non-cancer pain: Tapentadol, a step toward a solution?
    • Candiotti K.A., Gitlin M.C. Review of the effect of opioid-related side effects on the undertreatment of moderate to severe chronic non-cancer pain: Tapentadol, a step toward a solution?. Curr Med Res Opin 2010, 26:1677-1684.
    • (2010) Curr Med Res Opin , vol.26 , pp. 1677-1684
    • Candiotti, K.A.1    Gitlin, M.C.2
  • 22
    • 77954612709 scopus 로고    scopus 로고
    • Evaluation of study discontinuations with tapentadol immediate release and oxycodone immediate release in patients with low back or osteoarthritis pain
    • Vorsanger G., Xiang J., Okamoto A., et al. Evaluation of study discontinuations with tapentadol immediate release and oxycodone immediate release in patients with low back or osteoarthritis pain. J Opioid Manag 2010, 6:169-179.
    • (2010) J Opioid Manag , vol.6 , pp. 169-179
    • Vorsanger, G.1    Xiang, J.2    Okamoto, A.3
  • 23
    • 62149094353 scopus 로고    scopus 로고
    • Efficacy and tolerability of tapentadol immediate release and oxycodone HCL immediate release in patients awaiting primary joint replacement surgery for end-stage joint disease: A 10-day, phase III, randomized, double-blind, active- and placebo-controlled study
    • Hartrick C., Van Hove I., Stegmann J.U., et al. Efficacy and tolerability of tapentadol immediate release and oxycodone HCL immediate release in patients awaiting primary joint replacement surgery for end-stage joint disease: A 10-day, phase III, randomized, double-blind, active- and placebo-controlled study. Clin Ther 2009, 31:260-271.
    • (2009) Clin Ther , vol.31 , pp. 260-271
    • Hartrick, C.1    Van Hove, I.2    Stegmann, J.U.3
  • 24
    • 67649414317 scopus 로고    scopus 로고
    • Tolerability of tapentadol immediate release in patients with lower back pain or osteoarthritis of the hip or knee over 90 days: A randomized, double-blind study
    • Hale M., Upmalis D., Okamoto A., et al. Tolerability of tapentadol immediate release in patients with lower back pain or osteoarthritis of the hip or knee over 90 days: A randomized, double-blind study. Curr Med Res Opin 2009, 25:1095-1104.
    • (2009) Curr Med Res Opin , vol.25 , pp. 1095-1104
    • Hale, M.1    Upmalis, D.2    Okamoto, A.3
  • 25
    • 77954810443 scopus 로고    scopus 로고
    • Long-term safety and tolerability of tapentadol extended release for the management of chronic low back pain or osteoarthritis pain
    • Wild J.E., Grond S., Kuperwasser B., et al. Long-term safety and tolerability of tapentadol extended release for the management of chronic low back pain or osteoarthritis pain. Pain Pract 2010, 10:416-427.
    • (2010) Pain Pract , vol.10 , pp. 416-427
    • Wild, J.E.1    Grond, S.2    Kuperwasser, B.3
  • 26
    • 76149130647 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo- and active-controlled phase III study of tapentadol ER for chronic low back pain: Analysis of efficacy endpoint sensitivity
    • [abstract]
    • Etropolski M., Rauschkolb-Loffler C., Shapiro D., et al. A randomized, double-blind, placebo- and active-controlled phase III study of tapentadol ER for chronic low back pain: Analysis of efficacy endpoint sensitivity. J Pain 2009, 10(Suppl 4):S51. [abstract].
    • (2009) J Pain , vol.10 , Issue.SUPPL 4
    • Etropolski, M.1    Rauschkolb-Loffler, C.2    Shapiro, D.3
  • 27
    • 77954211482 scopus 로고    scopus 로고
    • Efficacy and safety of tapentadol extended release compared with oxycodone release for the management of moderate to severe chronic pain related to osteoarthritis of the knee: A randomized, double-blind, placebo- and active-controlled Phase III study
    • Afilalo M., Etropolski M.S., Kuperwasser B., et al. Efficacy and safety of tapentadol extended release compared with oxycodone release for the management of moderate to severe chronic pain related to osteoarthritis of the knee: A randomized, double-blind, placebo- and active-controlled Phase III study. Clin Drug Investig 2010, 30:489-505.
    • (2010) Clin Drug Investig , vol.30 , pp. 489-505
    • Afilalo, M.1    Etropolski, M.S.2    Kuperwasser, B.3
  • 28
    • 77954776260 scopus 로고    scopus 로고
    • Efficacy and safety of tapentadol extended release for the management of chronic low back pain: Results of a prospective, randomized, double-blind, placebo- and active-controlled phase III study
    • Buynak R., Shapiro D.Y., Okamoto A., et al. Efficacy and safety of tapentadol extended release for the management of chronic low back pain: Results of a prospective, randomized, double-blind, placebo- and active-controlled phase III study. Expert Opin Pharmacother 2010, 11:1787-1804.
    • (2010) Expert Opin Pharmacother , vol.11 , pp. 1787-1804
    • Buynak, R.1    Shapiro, D.Y.2    Okamoto, A.3
  • 29
    • 78650394491 scopus 로고    scopus 로고
    • Safety and efficacy of tapentadol ER in patients with painful diabetic peripheral neuropathy: Results of a randomized-withdrawal, placebo-controlled trial
    • Schwartz S., Etropolski M., Shapiro D.Y., et al. Safety and efficacy of tapentadol ER in patients with painful diabetic peripheral neuropathy: Results of a randomized-withdrawal, placebo-controlled trial. Curr Med Res Opin 2011, 27:151-162.
    • (2011) Curr Med Res Opin , vol.27 , pp. 151-162
    • Schwartz, S.1    Etropolski, M.2    Shapiro, D.Y.3
  • 30
    • 40949135791 scopus 로고    scopus 로고
    • Investigations into the drug-drug interaction potential of tapentadol in human liver microsomes and fresh human hepatocytes
    • Kneip C., Terlinden R., Beier H., et al. Investigations into the drug-drug interaction potential of tapentadol in human liver microsomes and fresh human hepatocytes. Drug Metab Lett 2008, 2:67-75.
    • (2008) Drug Metab Lett , vol.2 , pp. 67-75
    • Kneip, C.1    Terlinden, R.2    Beier, H.3
  • 31
    • 77957658753 scopus 로고    scopus 로고
    • A thorough QT/QTc study of multiple doses of tapentadol immediate release in healthy subjects
    • Oh C., Rengelshausen J., Mangold B., et al. A thorough QT/QTc study of multiple doses of tapentadol immediate release in healthy subjects. Int J Clin Pharmacol Ther 2010, 48:678-687.
    • (2010) Int J Clin Pharmacol Ther , vol.48 , pp. 678-687
    • Oh, C.1    Rengelshausen, J.2    Mangold, B.3
  • 32
    • 77956365463 scopus 로고    scopus 로고
    • Population pharmacokinetics of tapentadol immediate release (IR) in healthy subjects and patients with moderate or severe pain
    • Xu X.S., Smith J.W., Lin R., et al. Population pharmacokinetics of tapentadol immediate release (IR) in healthy subjects and patients with moderate or severe pain. Clin Pharmacokinet 2010, 49:671-682.
    • (2010) Clin Pharmacokinet , vol.49 , pp. 671-682
    • Xu, X.S.1    Smith, J.W.2    Lin, R.3
  • 33
    • 75149147267 scopus 로고    scopus 로고
    • Effects of acetaminophen, naproxen, and acetylsalicylic acid on tapentadol pharmacokinetics: Results of two randomized, open-label, crossover, drug-drug interaction studies
    • Smit J.W., Oh C., Rengelshausen J., et al. Effects of acetaminophen, naproxen, and acetylsalicylic acid on tapentadol pharmacokinetics: Results of two randomized, open-label, crossover, drug-drug interaction studies. Pharmacotherapy 2010, 30:25-34.
    • (2010) Pharmacotherapy , vol.30 , pp. 25-34
    • Smit, J.W.1    Oh, C.2    Rengelshausen, J.3
  • 34
    • 70450278677 scopus 로고    scopus 로고
    • Is tapentadol an advance on tramadol?
    • Guay D. Is tapentadol an advance on tramadol?. Consult Pharm 2009, 24:833-840.
    • (2009) Consult Pharm , vol.24 , pp. 833-840
    • Guay, D.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.