A more efficient method to generate null mutants using Hprt-Cre with floxed alleles

Journal of Pediatric Surgery

Volumn 46, Issue 9, 2011, Pages 1711-1719

  Nichol, Peter F ^a   Botham, Robert ^a   Saijoh, Yukio ^b   Reeder, Amy L ^a   Zaremba, Krzyztoff M ^a  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^b UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

Breeding strategy; Cre lox system; Efficiency; Generation of mutants; Homozygous null mutants; Hprt Cre; Knockout

Indexed keywords

CRE RECOMBINASE; FIBROBLAST GROWTH FACTOR RECEPTOR 3; FIBROBLAST GROWTH FACTOR RECEPTOR 3B; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BREEDING; CECUM DISEASE; COLON DISEASE; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; EXON; FEMALE; GENE EXPRESSION; GENETIC RECOMBINATION; GENOTYPE; HISTOPATHOLOGY; HOMOZYGOSITY; HYPOPHYSIS; INTESTINE ATRESIA; LIMB MALFORMATION; LITTER SIZE; LUNG MALFORMATION; MALE; MOUSE; NEWBORN; NONHUMAN; NULL ALLELE; PHENOTYPE; PRIORITY JOURNAL; TISSUE STRUCTURE;

ALLELES; ANIMALS; FEMALE; HOMOZYGOTE; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; MALE; MICE; MUTATION;

EID: 80053042701     PISSN: 00223468     EISSN: 15315037     Source Type: Journal    
DOI: 10.1016/j.jpedsurg.2011.01.023     Document Type: Article

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