Work-up optimization en route to an improved process to prepare a progesterone receptor antagonist

Organic Process Research and Development

Volumn 15, Issue 5, 2011, Pages 1081-1084

  De Koning, Pieter D ^a   McManus, David J ^a   Bandurek, George R ^a  

^a PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CHLOROMETHYL; EN-ROUTE; IMPROVED PROCESS; PARTIAL DEGRADATION; PROGESTERONE RECEPTOR; PYRAZOLES; ROOT CAUSE;

EID: 80053015360     PISSN: 10836160     EISSN: 1520586X     Source Type: Journal    
DOI: 10.1021/op200145j     Document Type: Article

References (2)

1. Bradley, P. A.; de Koning, P. D.; Johnson, P. S.; Lecouturier, Y. S.; McManus, D. J.; Robin, A.; Underwood, T. J. Org. Process Res. Dev. 2009, 13, 848
2. Greene., T. W.; Wuts, P. G. M. Protective Groups in Organic Synthesis, 3 rd ed.; Wiley-Interscience: New York, 1999; pp 33-35.