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Volumn 22, Issue 9, 2011, Pages 1083-1094

Use of DAF-displaying adenovirus vectors reduces induction of transgene-and vector-specific adaptive immune responses in mice

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; CAPSID PROTEIN; DECAY ACCELERATING FACTOR; GAMMA INTERFERON; N (4 METHOXYPHENYLACETYL)DEHYDROALANINE;

EID: 80053013727     PISSN: 10430342     EISSN: 15577422     Source Type: Journal    
DOI: 10.1089/hum.2010.218     Document Type: Article
Times cited : (13)

References (49)
  • 3
    • 57049106918 scopus 로고    scopus 로고
    • Complex interactions with several arms of the complement system dictate innate and humoral immunity to adenoviral vectors
    • Appledorn, D.M., McBride, A., Seregin, S., et al. (2008b). Complex interactions with several arms of the complement system dictate innate and humoral immunity to adenoviral vectors. Gene Ther. 15, 1606-1617.
    • (2008) Gene Ther. , vol.15 , pp. 1606-1617
    • Appledorn, D.M.1    McBride, A.2    Seregin, S.3
  • 4
    • 77949660661 scopus 로고    scopus 로고
    • A new adenovirus based vaccine vector expressing an Eimeria tenella derived TLR agonist improves cellular immune responses to an antigenic target
    • Appledorn, D.M., Aldhamen, Y.A., Depas, W., et al. (2010). A new adenovirus based vaccine vector expressing an Eimeria tenella derived TLR agonist improves cellular immune responses to an antigenic target. PLoS One 5, e9579.
    • (2010) PLoS One , vol.5
    • Appledorn, D.M.1    Aldhamen, Y.A.2    Depas, W.3
  • 5
    • 2442761730 scopus 로고    scopus 로고
    • Role of endogenous endonucleases and tissue site in transfection and CpG-mediated immune activation after naked DNA injection
    • DOI 10.1089/10430349950016816
    • Barry, M.E., Pinto-Gonzalez, D., Orson, F.M., et al. (1999). Role of endogenous endonucleases and tissue site in transfection and CpG-mediated immune activation after naked DNA injection. Hum. Gene Ther. 10, 2461-2480. (Pubitemid 29489721)
    • (1999) Human Gene Therapy , vol.10 , Issue.15 , pp. 2461-2480
    • Barry, M.E.1    Pinto-Gonzalez, D.2    Orson, F.M.3    McKenzie, G.J.4    Petry, G.R.5    Barry, M.A.6
  • 7
    • 0346256668 scopus 로고    scopus 로고
    • Liver toxicities typically induced by first-generation adenoviral vectors can be reduced by use of E1, E2b-deleted adenoviral vectors
    • Everett, R.S., Hodges, B.L., Ding, E.Y., et al. (2003). Liver toxi-cities typically induced by first-generation adenoviral vectors can be reduced by use of E1, E2b-deleted adenoviral vectors. Hum. Gene Ther. 14, 1715-1726. (Pubitemid 38010662)
    • (2003) Human Gene Therapy , vol.14 , Issue.18 , pp. 1715-1726
    • Everett, R.S.1    Hodges, B.L.2    Ding, E.Y.3    Xu, F.4    Serra, D.5    Amalfitano, A.6
  • 8
    • 49749103028 scopus 로고    scopus 로고
    • Complement-dependent enhancement of CD8\+ T cell immunity to lympho-cytic choriomeningitis virus infection in decay-accelerating factor-deficient mice
    • Fang, C., Miwa, T., Shen, H., and Song, W.C. (2007). Complement-dependent enhancement of CD8\+ T cell immunity to lympho-cytic choriomeningitis virus infection in decay-accelerating factor-deficient mice. J. Immunol. 179, 3178-3186.
    • (2007) J. Immunol. , vol.179 , pp. 3178-3186
    • Fang, C.1    Miwa, T.2    Shen, H.3    Song, W.C.4
  • 9
    • 0032521019 scopus 로고    scopus 로고
    • Local synthesis of C3 within the splenic lymphoid compartment can reconstitute the impaired immune response in C3-deficient mice
    • Fischer, M.B., Ma, M., Hsu, N.C., and Carroll, M.C. (1998). Local synthesis of C3 within the splenic lymphoid compartment can reconstitute the impaired immune response in C3-deficient mice. J. Immunol. 160, 2619-2625. (Pubitemid 28136711)
    • (1998) Journal of Immunology , vol.160 , Issue.6 , pp. 2619-2625
    • Fischer, M.B.1    Ma, M.2    Hsu, N.C.3    Carroll, M.C.4
  • 10
    • 35349024379 scopus 로고    scopus 로고
    • Immune responses to lentiviral vectors
    • DOI 10.2174/156652307782151515
    • Follenzi, A., Santambrogio, L., and Annoni, A. (2007). Immune responses to lentiviral vectors. Curr. Gene Ther. 7, 306-315. (Pubitemid 47595773)
    • (2007) Current Gene Therapy , vol.7 , Issue.5 , pp. 306-315
    • Follenzi, A.1    Santambrogio, L.2    Annoni, A.3
  • 11
    • 70350070724 scopus 로고    scopus 로고
    • Novel ade-novirus type 5 vaccine platform induces cellular immunity against HIV-1 Gag, Pol, Nef despite the presence of Ad5 immunity
    • Gabitzsch, E.S., Xu, Y., Yoshida, L.H., et al. (2009). Novel ade-novirus type 5 vaccine platform induces cellular immunity against HIV-1 Gag, Pol, Nef despite the presence of Ad5 immunity. Vaccine 27, 6394-6398.
    • (2009) Vaccine , vol.27 , pp. 6394-6398
    • Gabitzsch, E.S.1    Xu, Y.2    Yoshida, L.H.3
  • 12
    • 5144222255 scopus 로고    scopus 로고
    • Complement: A unique innate immune sensor for danger signals
    • DOI 10.1016/j.molimm.2004.06.011, PII S0161589004002184
    • Gasque, P. (2004). Complement: a unique innate immune sensor for danger signals. Mol. Immunol. 41, 1089-1098. (Pubitemid 39345390)
    • (2004) Molecular Immunology , vol.41 , Issue.11 SPEC. ISSUE , pp. 1089-1098
    • Gasque, P.1
  • 13
    • 33846799474 scopus 로고    scopus 로고
    • Adenovirus infection triggers a rapid, MyD88-regulated transcriptome response critical to acute-phase and adaptive immune responses in vivo
    • DOI 10.1128/JVI.01936-06
    • Hartman, Z.C., Kiang, A., Everett, R.S., et al. (2007). Adenovirus infection triggers a rapid, MyD88-regulated transcriptome response critical to acute-phase and adaptive immune responses in vivo. J. Virol. 81, 1796-1812. (Pubitemid 46214453)
    • (2007) Journal of Virology , vol.81 , Issue.4 , pp. 1796-1812
    • Hartman, Z.C.1    Kiang, A.2    Everett, R.S.3    Serra, D.4    Yang, X.Y.5    Clay, T.M.6    Amalfitano, A.7
  • 14
    • 38949207486 scopus 로고    scopus 로고
    • Adenovirus vector induced innate immune responses: Impact upon efficacy and toxicity in gene therapy and vaccine applications
    • DOI 10.1016/j.virusres.2007.10.005, PII S0168170207003668
    • Hartman, Z.C., Appledorn, D.M., and Amalfitano, A. (2008). Adenovirus vector induced innate immune responses: impact upon efficacy and toxicity in gene therapy and vaccine applications. Virus Res. 132, 1-14. (Pubitemid 351232078)
    • (2008) Virus Research , vol.132 , Issue.1-2 , pp. 1-14
    • Hartman, Z.C.1    Appledorn, D.M.2    Amalfitano, A.3
  • 15
    • 22544471801 scopus 로고    scopus 로고
    • Complement and Toll-like receptors: Key regulators of adaptive immune responses
    • DOI 10.1016/j.molimm.2005.06.028, PII S0161589005002051, 10th Meeting on Complement in Human Disease
    • Hawlisch, H., and Kohl, J. (2006). Complement and Toll-like receptors: key regulators of adaptive immune responses. Mol. Immunol. 43, 13-21. (Pubitemid 41021519)
    • (2006) Molecular Immunology , vol.43 , Issue.1-2 , pp. 13-21
    • Hawlisch, H.1    Kohl, J.2
  • 16
    • 34547095486 scopus 로고    scopus 로고
    • Toll-like receptors impact on safety and efficacy of gene transfer vectors
    • DOI 10.1038/sj.mt.6300217, PII 6300217
    • Hensley, S.E., and Amalfitano, A. (2007). Toll-like receptors impact on safety and efficacy of gene transfer vectors. Mol. Ther. 15, 1417-1422. (Pubitemid 47099298)
    • (2007) Molecular Therapy , vol.15 , Issue.8 , pp. 1417-1422
    • Hensley, S.E.1    Amalfitano, A.2
  • 18
    • 0034974898 scopus 로고    scopus 로고
    • Adenovirus vectors with the 100K gene deleted and their potential for multiple gene therapy applications
    • DOI 10.1128/JVI.75.13.5913-5920.2001
    • Hodges, B.L., Evans, H.K., Everett, R.S., et al. (2001). Adenovirus vectors with the 100K gene deleted and their potential for multiple gene therapy applications. J. Virol. 75, 5913-5920. (Pubitemid 32553121)
    • (2001) Journal of Virology , vol.75 , Issue.13 , pp. 5913-5920
    • Hodges, B.L.1    Evans, H.K.2    Everett, R.S.3    Ding, E.Y.4    Serra, D.5    Amalfitano, A.6
  • 19
    • 56149112944 scopus 로고    scopus 로고
    • Trafficking of antigen-specific CD8\+ T lymphocytes to mucosal surfaces following intramuscular vaccination
    • Kaufman, D.R., Liu, J., Carville, A., et al. (2008). Trafficking of antigen-specific CD8\+ T lymphocytes to mucosal surfaces following intramuscular vaccination. J. Immunol. 181, 4188-4198.
    • (2008) J. Immunol. , vol.181 , pp. 4188-4198
    • Kaufman, D.R.1    Liu, J.2    Carville, A.3
  • 20
    • 33845905781 scopus 로고    scopus 로고
    • T-cell regulation: With complements from innate immunity
    • DOI 10.1038/nri1994, PII NRI1994
    • Kemper, C., and Atkinson, J.P. (2007). T-cell regulation: with complements from innate immunity. Nat. Rev. Immunol. 7, 9-18. (Pubitemid 46020823)
    • (2007) Nature Reviews Immunology , vol.7 , Issue.1 , pp. 9-18
    • Kemper, C.1    Atkinson, J.P.2
  • 21
    • 33748070532 scopus 로고    scopus 로고
    • Multiple Innate Inflammatory Responses Induced after Systemic Adenovirus Vector Delivery Depend on a Functional Complement System
    • DOI 10.1016/j.ymthe.2006.03.024, PII S1525001606001444
    • Kiang, A., Hartman, Z.C., Everett, R.S., et al. (2006). Multiple innate inflammatory responses induced after systemic ade-novirus vector delivery depend on a functional complement system. Mol. Ther. 14, 588-598. (Pubitemid 44296088)
    • (2006) Molecular Therapy , vol.14 , Issue.4 , pp. 588-598
    • Kiang, A.1    Hartman, Z.C.2    Everett, R.S.3    Serra, D.4    Jiang, H.5    Frank, M.M.6    Amalfitano, A.7
  • 22
    • 68249099660 scopus 로고    scopus 로고
    • New insights on adenovirus as vaccine vectors
    • Lasaro, M.O., and Ertl, H.C. (2009). New insights on adenovirus as vaccine vectors. Mol. Ther. 177, 1333-1339.
    • (2009) Mol. Ther. , vol.177 , pp. 1333-1339
    • Lasaro, M.O.1    Ertl, H.C.2
  • 24
    • 58149267963 scopus 로고    scopus 로고
    • Immune control of an SIV challenge by a T-cell-based vaccine in rhesus monkeys
    • Liu, J., O'Brien, K.L., Lynch, D.M., et al. (2009). Immune control of an SIV challenge by a T-cell-based vaccine in rhesus monkeys. Nature 457, 87-91.
    • (2009) Nature , vol.457 , pp. 87-91
    • Liu, J.1    O'Brien, K.L.2    Lynch, D.M.3
  • 25
    • 22544467430 scopus 로고    scopus 로고
    • Complement amplification revisited
    • DOI 10.1016/j.molimm.2005.06.020, PII S0161589005001999, 10th Meeting on Complement in Human Disease
    • Lutz, H.U., and Jelezarova, E. (2006). Complement amplification revisited. Mol. Immunol. 43, 2-12. (Pubitemid 41021518)
    • (2006) Molecular Immunology , vol.43 , Issue.1-2 , pp. 2-12
    • Lutz, H.U.1    Jelezarova, E.2
  • 26
    • 33646707490 scopus 로고    scopus 로고
    • Protective immune responses against West Nile virus are primed by distinct complement activation pathways
    • DOI 10.1084/jem.20052388
    • Mehlhop, E., and Diamond, M.S. (2006). Protective immune responses against West Nile virus are primed by distinct complement activation pathways. J. Exp. Med. 203, 1371-1381. (Pubitemid 43736604)
    • (2006) Journal of Experimental Medicine , vol.203 , Issue.5 , pp. 1371-1381
    • Mehlhop, E.1    Diamond, M.S.2
  • 27
    • 19944405462 scopus 로고    scopus 로고
    • Complement activation is required for induction of a protective antibody response against West Nile virus infection
    • DOI 10.1128/JVI.79.12.7466-7477.2005
    • Mehlhop, E., Whitby, K., Oliphant, T., et al. (2005). Complement activation is required for induction of a protective antibody response against West Nile virus infection. J. Virol. 79, 7466-7477. (Pubitemid 40756783)
    • (2005) Journal of Virology , vol.79 , Issue.12 , pp. 7466-7477
    • Mehlhop, E.1    Whitby, K.2    Oliphant, T.3    Marri, A.4    Engle, M.5    Diamond, M.S.6
  • 28
    • 35349027352 scopus 로고    scopus 로고
    • Immune responses to AAV in clinical trials
    • DOI 10.2174/156652307782151425
    • Mingozzi, F., and High, K.A. (2007). Immune responses to AAV in clinical trials. Curr. Gene Ther. 7, 316-324. (Pubitemid 47595774)
    • (2007) Current Gene Therapy , vol.7 , Issue.5 , pp. 316-324
    • Mingozzi, F.1    High, K.A.2
  • 29
    • 22544457584 scopus 로고    scopus 로고
    • Strategies of therapeutic complement inhibition
    • DOI 10.1016/j.molimm.2005.06.014, PII S0161589005002075, 10th Meeting on Complement in Human Disease
    • Mollnes, T.E., and Kirschfink, M. (2006). Strategies of therapeutic complement inhibition. Mol. Immunol. 43, 107-121. (Pubitemid 41021527)
    • (2006) Molecular Immunology , vol.43 , Issue.1-2 , pp. 107-121
    • Mollnes, T.E.1    Kirschfink, M.2
  • 30
    • 14744270215 scopus 로고    scopus 로고
    • Complement: Central to innate immunity and bridging to adaptive responses
    • DOI 10.1016/j.imlet.2004.11.010
    • Morgan, B.P., Marchbank, K.J., Longhi, M.P., et al. (2005). Complement: central to innate immunity and bridging to adaptive responses. Immunol. Lett. 97, 171-179. (Pubitemid 40326948)
    • (2005) Immunology Letters , vol.97 , Issue.2 SPEC. ISSUE , pp. 171-179
    • Morgan, B.P.1    Marchbank, K.J.2    Longhi, M.P.3    Harris, C.L.4    Gallimore, A.M.5
  • 31
    • 0035988785 scopus 로고    scopus 로고
    • Construction of first-generation adenoviral vectors
    • Ng, P., and Graham, F.L. (2002). Construction of first-generation adenoviral vectors. Methods Mol. Med. 69, 389-414.
    • (2002) Methods Mol. Med. , vol.69 , pp. 389-414
    • Ng, P.1    Graham, F.L.2
  • 32
    • 13844251902 scopus 로고    scopus 로고
    • Helper-dependent adenoviral vectors for gene therapy
    • DOI 10.1089/hum.2005.16.1
    • Palmer, D.J., and Ng, P. (2005). Helper-dependent adenoviral vectors for gene therapy. Hum. Gene Ther. 16, 1-16. (Pubitemid 40250327)
    • (2005) Human Gene Therapy , vol.16 , Issue.1 , pp. 1-16
    • Palmer, D.J.1    Ng, P.2
  • 33
    • 2142730100 scopus 로고    scopus 로고
    • Central memory and effector memory T cell subsets: Function, generation, and maintenance
    • DOI 10.1146/annurev.immunol.22.012703.104702
    • Sallusto, F., Geginat, J., and Lanzavecchia, A. (2004). Central memory and effector memory T cell subsets: function, generation, and maintenance. Annu. Rev. Immunol. 22, 745-763. (Pubitemid 38680440)
    • (2004) Annual Review of Immunology , vol.22 , pp. 745-763
    • Sallusto, F.1    Geginat, J.2    Lanzavecchia, A.3
  • 34
    • 0034633740 scopus 로고    scopus 로고
    • Efficient transformation of primary human amniocytes by E1 functions of Ad5: Generation of new cell lines for adenoviral vector production
    • Schiedner, G., Hertel, S., and Kochanek, S. (2000). Efficient transformation of primary human amniocytes by E1 functions of Ad5: generation of new cell lines for adenoviral vector production. Hum. Gene Ther. 11, 2105-2116.
    • (2000) Hum. Gene Ther. , vol.11 , pp. 2105-2116
    • Schiedner, G.1    Hertel, S.2    Kochanek, S.3
  • 35
    • 70450164178 scopus 로고    scopus 로고
    • Overcoming preexisting adenovirus immunity by genetic engineering of adenovirus-based vectors
    • Seregin, S.S., and Amalfitano, A. (2009). Overcoming preexisting adenovirus immunity by genetic engineering of adenovirus-based vectors. Expert Opin. Biol. Ther. 9, 1521-1531.
    • (2009) Expert Opin. Biol. Ther. , vol.9 , pp. 1521-1531
    • Seregin, S.S.1    Amalfitano, A.2
  • 36
    • 79952157413 scopus 로고    scopus 로고
    • Improving adenovirus based gene transfer: Strategies to accomplish immune evasion
    • Seregin, S.S., and Amalfitano, A. (2010). Improving adenovirus based gene transfer: strategies to accomplish immune evasion. Viruses 2, 2013-2036.
    • (2010) Viruses , vol.2 , pp. 2013-2036
    • Seregin, S.S.1    Amalfitano, A.2
  • 37
    • 70350164253 scopus 로고    scopus 로고
    • CR1/2 is an important suppressor of adenovirus-induced innate immune responses and is required for induction of neutralizing antibodies
    • Seregin, S.S., Aldhamen, Y.A., Appledorn, D.M., et al. (2009a). CR1/2 is an important suppressor of adenovirus-induced innate immune responses and is required for induction of neutralizing antibodies. Gene Ther. 16, 1245-1259.
    • (2009) Gene Ther. , vol.16 , pp. 1245-1259
    • Seregin, S.S.1    Aldhamen, Y.A.2    Appledorn, D.M.3
  • 38
    • 63949084441 scopus 로고    scopus 로고
    • Transient pretreatment with glucocorticoid ablates innate toxicity of systemically delivered adenoviral vectors without reducing efficacy
    • Seregin, S.S., Appledorn, D.M., McBride, A.J., et al. (2009b). Transient pretreatment with glucocorticoid ablates innate toxicity of systemically delivered adenoviral vectors without reducing efficacy. Mol. Ther. 17, 685-696.
    • (2009) Mol. Ther. , vol.17 , pp. 685-696
    • Seregin, S.S.1    Appledorn, D.M.2    McBride, A.J.3
  • 39
    • 77956562865 scopus 로고    scopus 로고
    • Adenovirus capsid-display of the retro-oriented human complement inhibitor DAF reduces Ad vector-triggered immune responses in vitro and in vivo
    • Seregin, S.S., Aldhamen, Y.A., Appledorn, D.M., et al. (2010a). Adenovirus capsid-display of the retro-oriented human complement inhibitor DAF reduces Ad vector-triggered immune responses in vitro and in vivo. Blood 116, 1669-1677.
    • (2010) Blood , vol.116 , pp. 1669-1677
    • Seregin, S.S.1    Aldhamen, Y.A.2    Appledorn, D.M.3
  • 40
    • 77954042715 scopus 로고    scopus 로고
    • Novel adenovirus vectors 'capsid-displaying' a human complement inhibitor
    • Seregin, S.S., Hartman, Z.C., Appledorn, D.M., et al. (2010b). Novel adenovirus vectors 'capsid-displaying' a human complement inhibitor. J. Innate Immun. 2, 353-359.
    • (2010) J. Innate Immun. , vol.2 , pp. 353-359
    • Seregin, S.S.1    Hartman, Z.C.2    Appledorn, D.M.3
  • 42
    • 0037438634 scopus 로고    scopus 로고
    • Complement component 3 is required for optimal expansion of CD8 T cells during a systemic viral infection
    • Suresh, M., Molina, H., Salvato, M.S., et al. (2003). Complement component 3 is required for optimal expansion of CD8 T cells during a systemic viral infection. J. Immunol. 170, 788-794. (Pubitemid 36070530)
    • (2003) Journal of Immunology , vol.170 , Issue.2 , pp. 788-794
    • Suresh, M.1    Molina, H.2    Salvato, M.S.3    Mastellos, D.4    Lambris, J.D.5    Sandor, M.6
  • 44
    • 66149123049 scopus 로고    scopus 로고
    • Adenovirus activates complement by distinctly different mechanisms in vitro and in vivo: Indirect complement activation by virions in vivo
    • Tian, J., Xu, Z., Smith, J.S., et al. (2009). Adenovirus activates complement by distinctly different mechanisms in vitro and in vivo: indirect complement activation by virions in vivo. J. Virol. 83, 5648-5658.
    • (2009) J. Virol. , vol.83 , pp. 5648-5658
    • Tian, J.1    Xu, Z.2    Smith, J.S.3
  • 46
    • 0029936764 scopus 로고    scopus 로고
    • Immune responses to transgene-encoded proteins limit the stability of gene expression after injection of replication-defective adenovirus vectors
    • Tripathy, S.K., Black, H.B., Goldwasser, E., and Leiden, J.M. (1996). Immune responses to transgene-encoded proteins limit the stability of gene expression after injection of replication-defective adenovirus vectors. Nat. Med. 2, 545-550.
    • (1996) Nat. Med. , vol.2 , pp. 545-550
    • Tripathy, S.K.1    Black, H.B.2    Goldwasser, E.3    Leiden, J.M.4
  • 47
    • 57749193282 scopus 로고    scopus 로고
    • Effects of shielding ade-noviral vectors with polyethylene glycol (PEG) on vector-specific and vaccine-mediated immune responses
    • Weaver, E.A., and Barry, M.A. (2008). Effects of shielding ade-noviral vectors with polyethylene glycol (PEG) on vector-specific and vaccine-mediated immune responses. Hum. Gene Ther. 19, 1369-1382.
    • (2008) Hum. Gene Ther. , vol.19 , pp. 1369-1382
    • Weaver, E.A.1    Barry, M.A.2
  • 48
    • 0347480382 scopus 로고    scopus 로고
    • Intravenous administration of replication-incompetent adenovirus to rhesus monkeys induces thrombocytopenia by increasing in vivo platelet clearance
    • DOI 10.1046/j.1365-2141.2003.04719.x
    • Wolins, N., Lozier, J., Eggerman, T.L., et al. (2003). Intravenous administration of replication-incompetent adenovirus to rhesus monkeys induces thrombocytopenia by increasing in vivo platelet clearance. Br. J. Haematol. 123, 903-905. (Pubitemid 37533303)
    • (2003) British Journal of Haematology , vol.123 , Issue.5 , pp. 903-905
    • Wolins, N.1    Lozier, J.2    Eggerman, T.L.3    Jones, E.4    Aguilar-Cordova, E.5    Vostal, J.G.6
  • 49
    • 21244441929 scopus 로고    scopus 로고
    • Immune responses to adeno-associated virus vectors
    • DOI 10.2174/1566523054065039
    • Zaiss, A.K., and Muruve, D.A. (2005). Immune responses to adeno-associated virus vectors. Curr. Gene Ther. 5, 323-331. (Pubitemid 40895016)
    • (2005) Current Gene Therapy , vol.5 , Issue.3 , pp. 323-331
    • Zaiss, A.K.1    Muruve, D.A.2


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