Angiotensin II type i receptor blockade suppresses glomerular renin-angiotensin system activation, oxidative stress, and progressive glomerular injury in rat anti-glomerular basement membrane glomerulonephritis

Translational Research

Volumn 158, Issue 4, 2011, Pages 235-248

  Kinoshita, Yukiko ^a   Kondo, Shuji ^a   Urushihara, Maki ^a   Suga, Kenichi ^a   Matsuura, Sato ^a   Takamatsu, Masanori ^a   Shimizu, Maki ^a   Nishiyama, Akira ^b   Kawachi, Hiroshi ^c   Kagami, Shoji ^a  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

^b KAGAWA UNIVERSITY   (Japan)

^c NIIGATA UNIVERSITY GRADUATE SCHOOL OF MEDICAL AND DENTAL SCIENCES   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN II; ANGIOTENSINOGEN; CANDESARTAN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SUPEROXIDE; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; GLOMERULAR STRUCTURE; GLOMERULONEPHRITIS; GLOMERULOSCLEROSIS; MACROPHAGE; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEINURIA; RAPIDLY PROGRESSIVE GLOMERULONEPHRITIS; RAT; RECEPTOR BLOCKING; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM;

EID: 80052995723     PISSN: 19315244     EISSN: 18781810     Source Type: Journal    
DOI: 10.1016/j.trsl.2011.05.003     Document Type: Article

References (39)

1. W.A. Border, and N.A. Noble Transforming growth factor beta in tissue fibrosis N Engl J Med 331 1994 1286 1292 (Pubitemid 24333194)
2. R.C. Atkins, D.J. Nikolic-Paterson, Q. Song, and H.Y. Lan Modulators of crescentic glomerulonephritis J Am Soc Nephrol 7 1996 2271 2278 (Pubitemid 27465931)
3. S.V. Shah, R. Baliga, M. Rajapurkar, and V.A. Fonseca Oxidants in chronic kidney disease J Am Soc Nephrol 18 2007 16 28 (Pubitemid 46053418)
4. P.G. Tipping, and S.R. Holdsworth Cytokines in glomerulonephritis Semin Nephrol 27 2007 275 285 (Pubitemid 46802914)
5. R. Coppo, L. Peruzzi, and A. Amore IgACE: a placebo-controlled, randomized trial of angiotensin-converting enzyme inhibitors in children and young people with IgA nephropathy and moderate proteinuria J Am Soc Nephrol 18 2007 1880 1888 (Pubitemid 46870324)
6. E.J. Lewis, L.G. Hunsicker, and W.R. Clarke Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes N Engl J Med 345 2001 851 860
7. M.W. Taal, and B.M. Brenner Renoprotective benefits of RAS inhibition: from ACEI to angiotensin II antagonists Kidney Int 57 2000 1803 1817 (Pubitemid 30252273)
8. Y. Suzuki, I. Shirato, and K. Okumura Distinct contribution of Fc receptors and angiotensin II-dependent pathways in anti-GBM glomerulonephritis Kidney Int 54 1998 1166 1174 (Pubitemid 28449903)
9. S. Kondo, M. Shimizu, and M. Urushihara Addition of the antioxidant probucol to angiotensin II type I receptor antagonist arrests progressive mesangioproliferative glomerulonephritis in the rat J Am Soc Nephrol 17 2006 783 794
10. A.T. Whaley-Connell, N.A. Chowdhury, and M.R. Hayden Oxidative stress and glomerular filtration barrier injury: role of the renin-angiotensin system in the Ren2 transgenic rat Am J Physiol Renal Physiol 291 2006 F1308 F1314
11. S. Kagami, W.A. Border, D.E. Miller, and N.A. Noble Angiotensin II stimulates extracellular matrix protein synthesis-induction of transforming growth factor-beta expression in rat glomerular mesangial cells J Clin Invest 93 1994 2431 2437 (Pubitemid 24177156)
12. A. Sachse, and G. Wolf Angiotensin II-induced reactive oxygen species and the kidney J Am Soc Nephrol 18 2007 2439 2446 (Pubitemid 47378859)
13. M. Ruiz-Ortega, M. Ruperez, and O. Lorenzo Angiotensin II regulates the synthesis of proinflammatory cytokines and chemokines in the kidney Kidney Int suppl 2002 S12 S22
14. H.H. Hsu, S. Hoffmann, and N. Endlich Mechanisms of angiotensin II signaling on cytoskeleton of podocytes J Mol Med 86 2008 1379 1394
15. M. Takamatsu, M. Urushihara, and S. Kondo Glomerular angiotensinogen protein is enhanced in pediatric IgA nephropathy Pediatr Nephrol 23 2008 1257 1267
16. R. Singh, A.K. Singh, and D.J. Leehey A novel mechanism for angiotensin II formation in streptozotocin-diabetic rat glomeruli Am J Physiol Renal Physiol 288 2005 F1183 F1190
17. D. Del Prete, G. Gambaro, and A. Lupo Precocious activation of genes of the renin-angiotensin system and the fibrogenic cascade in IgA glomerulonephritis Kidney Int 64 2003 149 159 (Pubitemid 36714167)
18. J.R. Ingelfinger, W.M. Zuo, E.A. Fon, K.E. Ellison, and V.J. Dzau In situ hybridization evidence for angiotensinogen messenger RNA in the rat proximal tubule. An hypothesis for the intrarenal renin angiotensin system J Clin Invest 85 1990 417 423 (Pubitemid 20070047)
19. M.G. Seikaly, B.S. Arant Jr., and F.D. Seney Jr. Endogenous angiotensin concentrations in specific intrarenal fluid compartments of the rat J Clin Invest 86 1990 1352 1357 (Pubitemid 20370446)
20. J. Obata, T. Nakamura, and H. Takano Increased gene expression of components of the renin-angiotensin system in glomeruli of genetically hypertensive rats J Hypertens 18 2000 1247 1255
21. D.J. Leehey, A.K. Singh, J.P. Bast, P. Sethupathi, and R. Singh Glomerular renin angiotensin system in streptozotocin diabetic and Zucker diabetic fatty rats Transl Res 151 2008 208 216
22. M. Shimizu, S. Kondo, and M. Urushihara Role of integrin-linked kinase in epithelial-mesenchymal transition in crescent formation of experimental glomerulonephritis Nephrol Dial Transplant 21 2006 2380 2390 (Pubitemid 44644508)
23. M.W. Taal, K. Zandi-Nejad, and B. Weening Proinflammatory gene expression and macrophage recruitment in the rat remnant kidney Kidney Int 58 2000 1664 1676
24. M.E. Fabiani, D.T. Dinh, L. Nassis, D.J. Casley, and C.I. Johnston In vivo inhibition of angiotensin receptors in the rat kidney by candesartan cilexetil: a comparison with losartan Am J Hypertens 13 2000 1005 1013
25. H. Kobori, Y. Ozawa, Y. Suzaki, and A. Nishiyama Enhanced intrarenal angiotensinogen contributes to early renal injury in spontaneously hypertensive rats J Am Soc Nephrol 16 2005 2073 2080 (Pubitemid 41716438)
26. H. Kobori, M. Nangaku, L.G. Navar, and A. Nishiyama The intrarenal renin-angiotensin system: from physiology to the pathobiology of hypertension and kidney disease Pharmacol Rev 59 2007 251 287 (Pubitemid 47481436)
27. J.R. Ingelfinger, F. Jung, and D. Diamant Rat proximal tubule cell line transformed with origin-defective SV40 DNA: autocrine ANG II feedback Am J Physiol 276 1999 F218 F227
28. R.E. Schmieder Mechanisms for the clinical benefits of angiotensin II receptor blockers Am J Hypertens 18 2005 720 730 (Pubitemid 40692442)
29. D.J. Nikolic-Paterson, and R.C. Atkins The role of macrophages in glomerulonephritis Nephrol Dial Transplant 16 2001 3 7 (Pubitemid 32750422)
30. Y. Hisada, T. Sugaya, and M. Yamanouchi Angiotensin II plays a pathogenic role in immune-mediated renal injury in mice J Clin Invest 103 1999 627 635 (Pubitemid 29122415)
31. M. Ruiz-Ortega, C. Bustos, and M.A. Hernandez-Presa Angiotensin II participates in mononuclear cell recruitment in experimental immune complex nephritis-nuclear factor-kappa B activation and monocyte chemoattractant protein-1 synthesis J Immunol 161 1998 430 439 (Pubitemid 28285552)
32. M. Ravera, M. Re, L. Deferrari, S. Vettoretti, and G. Deferrari Importance of blood pressure control in chronic kidney disease J Am Soc Nephrol 17 2006 S98 S103
33. X.R. Huang, A.C. Chung, L. Zhou, X.J. Wang, and H.Y. Lan Latent TGF-beta1 protects against crescentic glomerulonephritis J Am Soc Nephrol 19 2008 233 242 (Pubitemid 351240645)
34. A. Zhou, H. Ueno, and M. Shimomura Blockade of TGF-beta action ameliorates renal dysfunction and histologic progression in anti-GBM nephritis Kidney Int 64 2003 92 101 (Pubitemid 36714161)
35. D.Y. Rhyu, Y. Yang, and H. Ha Role of reactive oxygen species in TGF-beta1-induced mitogen-activated protein kinase activation and epithelial-mesenchymal transition in renal tubular epithelial cells J Am Soc Nephrol 16 2005 667 675 (Pubitemid 41725103)
36. A. Djamali, A. Vidyasagar, M. Adulla, D. Hullett, and S. Reese Nox-2 is a modulator of fibrogenesis in kidney allografts Am J Transplant 9 2009 74 82
37. C.D. Bondi, N. Manickam, and D.Y. Lee NAD(P)H oxidase mediates TGF-beta1-induced activation of kidney myofibroblasts J Am Soc Nephrol 21 2010 93 102
38. K. Sebekova, M. Lill, P. Boor, A. Heidland, and K. Amann Functional and partial morphological regression of established renal injury in the obese zucker rat by blockade of the renin-angiotensin system Am J Nephrol 29 2009 164 170
39. G.L. Bakris, and M.R. Weir Angiotensin-converting enzyme inhibitor-associated elevations in serum creatinine: is this a cause for concern? Arch Intern Med 160 2000 685 693 (Pubitemid 30140419)