The achilles heel of cardiovascular genetic testing: Distinguishing pathogenic mutations from background genetic noise

Clinical Pharmacology and Therapeutics

Volumn 90, Issue 4, 2011, Pages 496-499

  Landstrom, A P ^a   Ackerman, M J ^a  

^a MAYO GRADUATE SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TROPOMYOSIN; DESMOCOLLIN 2; DESMOGLEIN 2; DESMOPLAKIN; MYOSIN BINDING PROTEIN C; MYOSIN HEAVY CHAIN; MYOSIN LIGHT CHAIN; PLAKOGLOBIN; PLAKOPHILIN 2; POTASSIUM CHANNEL; POTASSIUM CHANNEL KCNH2; POTASSIUM CHANNEL KCNQ1; PROTEIN; SODIUM CHANNEL NAV1.5; TRANSMEMBRANE PROTEIN 43; TROPONIN C; TROPONIN I; TROPONIN T; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; CARBOXY TERMINAL SEQUENCE; CARDIOVASCULAR SYSTEM EXAMINATION; CATECHOLAMINERGIC POLYMORPHIC VENTRICULAR TACHYCARDIA; GENE MUTATION; GENETIC SCREENING; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; HEART RIGHT VENTRICLE DYSPLASIA; HUMAN; HYPERTROPHIC CARDIOMYOPATHY; LONG QT SYNDROME; MISSENSE MUTATION; PREDICTIVE VALUE; PRIORITY JOURNAL; PROTEIN DOMAIN; QT PROLONGATION; REVIEW; SIGNAL NOISE RATIO; SUDDEN DEATH;

CARDIOVASCULAR DISEASES; HEALTH BEHAVIOR; HUMANS; WORLD HEALTH;

EID: 80052989000     PISSN: 00099236     EISSN: 15326535     Source Type: Journal    
DOI: 10.1038/clpt.2011.192     Document Type: Review

References (9)

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