Embryonic anti-aging niche

Aging

Volumn 3, Issue 5, 2011, Pages 555-563

  Conboy, Irina M ^a   Yousef, Hanadie ^b   Conboy, Michael J ^a  

^a University of California at Berkeley   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Cell cycle; hESC; MAPK; Muscle; Niche; Notch; Regeneration; Senescent; Stem cell aging; TGF

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE;

AGING; ANIMAL; ANIMAL EMBRYO; ARTICLE; CYTOLOGY; HUMAN; METABOLISM; PHYSIOLOGY; REGENERATION; SIGNAL TRANSDUCTION; SKELETAL MUSCLE SATELLITE CELL; STEM CELL; STEM CELL NICHE;

AGING; ANIMALS; EMBRYO, MAMMALIAN; HUMANS; MITOGEN-ACTIVATED PROTEIN KINASES; REGENERATION; SATELLITE CELLS, SKELETAL MUSCLE; SIGNAL TRANSDUCTION; STEM CELL NICHE; STEM CELLS;

EID: 80052985938     PISSN: 19454589     EISSN: None     Source Type: Journal    
DOI: 10.18632/aging.100333     Document Type: Article

References (62)

1. Vijg J and Campisi J. Puzzles, promises and a cure for ageing. Nature. 2008; 454:1065-71
2. Kikis EA, Gidalevitz T and Morimoto RI. Protein homeostasis in models of aging and age-related conformational disease. Adv Exp Med Biol. 2010; 694:138-59
3. Nakamura T, Gu Z and Lipton SA. Contribution of glutamatergic signaling to nitrosative stress-induced protein misfolding in normal brain aging and neurodegenerative diseases. Aging Cell. 2007; 6:351-9
4. Campisi J and Vijg J. Does damage to DNA and other macromolecules play a role in aging? If so, how? J Gerontol A Biol Sci Med Sci. 2009; 64:175-8
5. Drummond-Barbosa D. Stem cells, their niches and the systemic environment: an aging network. Genetics. 2008; 180:1787-97
6. Symonds CE, Galderisi U and Giordano A. Aging of the inceptive cellular population: the relationship between stem cells and aging. Aging (Albany NY). 2009; 1:372-81
7. Blagosklonny MV. Revisiting the antagonistic pleiotropy theory of aging: TOR-driven program and quasi-program. Cell Cycle. 2010; 9:3151-6
8. Selman C, Tullet JM, Wieser D, Irvine E, Lingard SJ, Choudhury AI, Claret M, Al-Qassab H, Carmignac D, Ramadani F, Woods A, Robinson IC, Schuster E, et al. Ribosomal protein S6 kinase 1 signaling regulates mammalian life span. Science. 2009; 326:140-4
9. Harrison DE, Strong R, Sharp ZD, Nelson JF, Astle CM, Flurkey K, Nadon NL, Wilkinson JE, Frenkel K, Carter CS, Pahor M, Javors MA, Fernandez E, et al. Rapamycin fed late in life extends lifespan in genetically heterogeneous mice. Nature. 2009; 460:392-5
10. Miller RA, Harrison DE, Astle CM, Baur JA, Boyd AR, de Cabo R, Fernandez E, Flurkey K, Javors MA, Nelson JF, Orihuela CJ, Pletcher S, Sharp ZD, et al. Rapamycin, but not resveratrol or simvastatin, extends life span of genetically heterogeneous mice. J Gerontol A Biol Sci Med Sci. 2011; 66:191-201
11. Dai Z, Wu F, Yeung EW and Li Y. IGF-IEc expression, regulation and biological function in different tissues. Growth Horm IGF Res. 2010; 20:275-81
12. Dickinson BC, Peltier J, Stone D, Schaffer DV and Chang CJ. Nox2 redox signaling maintains essential cell populations in the brain. Nat Chem Biol. 2011; 7:106-12
13. Conboy IM, Conboy MJ, Smythe GM and Rando TA. Notchmediated restoration of regenerative potential to aged muscle. Science. 2003; 302:1575-1577
14. Conboy IM, Conboy MJ, Wagers AJ, Girma ER, Weissman IL and Rando TA. Rejuvenation of aged progenitor cells by exposure to a young systemic environment. Nature. 2005; 433:760-764
15. Conboy IM and Rando TA. Aging, stem cells and tissue regeneration: lessons from muscle. Cell Cycle. 2005; 4:407-410
16. Carlson ME, Hsu M and Conboy IM. Imbalance between pSmad3 and Notch induces CDK inhibitors in old muscle stem cells. Nature. 2008; 454:528-32
17. Carlson ME, Conboy MJ, Hsu M, Barchas L, Jeong J, Agrawal A, Mikels AJ, Agrawal S, Schaffer DV and Conboy IM. Relative roles of TGF-beta1 and Wnt in the systemic regulation and aging of satellite cell responses. Aging Cell. 2009; 8:676-89
18. Carlson ME, Suetta C, Conboy MJ, Aagaard P, Mackey A, Kjaer M and Conboy I. Molecular aging and rejuvenation of human muscle stem cells. EMBO Mol Med. 2009; 1:381-91
19. Brack AS, Conboy MJ, Roy S, Lee M, Kuo CJ, Keller C and Rando TA. Increased Wnt signaling during aging alters muscle stem cell fate and increases fibrosis. Science. 2007; 317:807-10
20. Carlson ME and Conboy IM. Loss of stem cell regenerative capacity within aged niches. Aging Cell. 2007; 6:371-82
21. Vinciguerra M, Musaro A and Rosenthal N. Regulation of muscle atrophy in aging and disease. Adv Exp Med Biol. 2010; 694:211-33
22. Sharpless NE and DePinho RA. How stem cells age and why this makes us grow old. Nat Rev Mol Cell Biol. 2007; 8:703-13
23. Krishnamurthy J, Ramsey MR, Ligon KL, Torrice C, Koh A, Bonner-Weir S and Sharpless NE. p16INK4a induces an agedependent decline in islet regenerative potential. Nature. 2006; 443:453-457
24. Molofsky AV, Slutsky SG, Joseph NM, He S, Pardal R, Krishnamurthy J, Sharpless NE and Morrison SJ. Increasing p16INK4a expression decreases forebrain progenitors and neurogenesis during ageing. Nature. 2006; 443:448-52
25. Janzen V, Forkert R, Fleming HE, Saito Y, Waring MT, Dombkowski DM, Cheng T, DePinho RA, Sharpless NE and Scadden DT. Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a. Nature. 2006; 443:421-426
26. Liu Y, Johnson SM, Fedoriw Y, Rogers AB, Yuan H, Krishnamurthy J and Sharpless NE. Expression of p16(INK4a) prevents cancer and promotes aging in lymphocytes. Blood. 2011; 117:3257-67
27. Rodier F and Campisi J. Four faces of cellular senescence. J Cell Biol. 2011; 192:547-56
28. Rodier F, Coppe JP, Patil CK, Hoeijmakers WA, Munoz DP, Raza SR, Freund A, Campeau E, Davalos AR and Campisi J. Persistent DNA damage signalling triggers senescenceassociated inflammatory cytokine secretion. Nat Cell Biol. 2009; 11:973-9
29. Freund A, Orjalo AV, Desprez PY and Campisi J. Inflammatory networks during cellular senescence: causes and consequences. Trends Mol Med. 2010; 16:238-46
30. Tomas-Loba A, Flores I, Fernandez-Marcos PJ, Cayuela ML, Maraver A, Tejera A, Borras C, Matheu A, Klatt P, Flores JM, Vina J, Serrano M and Blasco MA. Telomerase reverse transcriptase delays aging in cancer-resistant mice. Cell. 2008; 135:609-22
31. Park JS, Kim YS and Yoo MA. The role of p38b MAPK in agerelated modulation of intestinal stem cell proliferation and differentiation in Drosophila. Aging (Albany NY). 2009; 1:637-51
32. Keshet Y and Seger R. The MAP kinase signaling cascades: a system of hundreds of components regulates a diverse array of physiological functions. Methods Mol Biol. 2010; 661:3-38
33. Huang H, Patel DD and Manton KG. The immune system in aging: roles of cytokines, T cells and NK cells. Front Biosci. 2005; 10:192-215
34. Racila D and Bickenbach JR. Are epidermal stem cells unique with respect to aging? Aging (Albany NY). 2009; 1:746-50
35. Niikura Y, Niikura T and Tilly JL. Aged mouse ovaries possess rare premeiotic germ cells that can generate oocytes following transplantation into a young host environment. Aging (Albany NY). 2009; 1:971-8
36. Massasa E, Costa XS and Taylor HS. Failure of the stem cell niche rather than loss of oocyte stem cells in the aging ovary. Aging (Albany NY). 2010; 2:1-2
37. Virant-Klun I and Skutella T. Stem cells in aged mammalian ovaries. Aging (Albany NY). 2010; 2:3-6
38. Park H, Cannizzaro C, Vunjak-Novakovic G, Langer R, Vacanti CA and Farokhzad OC. Nanofabrication and microfabrication of functional materials for tissue engineering. Tissue Eng. 2007; 13:1867-77
39. Huebsch N and Mooney DJ. Inspiration and application in the evolution of biomaterials. Nature. 2009; 462:426-32
40. Sands RW and Mooney DJ. Polymers to direct cell fate by controlling the microenvironment. Curr Opin Biotechnol. 2007; 18:448-53
41. Carlson BM and Faulkner JA. Muscle transplantation between young and old rats: age of host determines recovery. Am J Physiol. 1989; 256:C1262-6
42. Imayoshi I, Sakamoto M, Yamaguchi M, Mori K and Kageyama R. Essential roles of Notch signaling in maintenance of neural stem cells in developing and adult brains. J Neurosci. 2010; 30:3489-98
43. Dey BK, Gagan J and Dutta A. miR-206 and -486 induce myoblast differentiation by downregulating Pax7. Mol Cell Biol. 2011; 31:203-14
44. Chen JF, Tao Y, Li J, Deng Z, Yan Z, Xiao X and Wang DZ. microRNA-1 and microRNA-206 regulate skeletal muscle satellite cell proliferation and differentiation by repressing Pax7. J Cell Biol. 2010; 190:867-79
45. Hirai H, Verma M, Watanabe S, Tastad C, Asakura Y and Asakura A. MyoD regulates apoptosis of myoblasts through microRNA-mediated down-regulation of Pax3. J Cell Biol. 2010; 191:347-65
46. Brett JO, Renault VM, Rafalski VA, Webb AE and Brunet A. The microRNA cluster miR-106b~25 regulates adult neural stem/progenitor cell proliferation and neuronal differentiation. Aging (Albany NY). 2011; 3:108-24
47. Rizzo P, Osipo C, Foreman K, Golde T, Osborne B and Miele L. Rational targeting of Notch signaling in cancer. Oncogene. 2008; 27:5124-31
48. Lea IA, Jackson MA, Li X, Bailey S, Peddada SD and Dunnick JK. Genetic pathways and mutation profiles of human cancers: site- and exposure-specific patterns. Carcinogenesis. 2007; 28:1851-8
49. Meloche S and Pouyssegur J. The ERK1/2 mitogen-activated protein kinase pathway as a master regulator of the G1- to Sphase transition. Oncogene. 2007; 26:3227-39
50. Cooper K. Rb, whi it's not just for metazoans anymore. Oncogene. 2006; 25:5228-32
51. Levi BP and Morrison SJ. Stem cells use distinct self-renewal programs at different ages. Cold Spring Harb Symp Quant Biol. 2008; 73:539-53
52. He S, Nakada D and Morrison SJ. Mechanisms of stem cell self-renewal. Annu Rev Cell Dev Biol. 2009; 25:377-406
53. Wobus AM and Boheler KR. Embryonic stem cells: prospects for developmental biology and cell therapy. Physiol Rev. 2005; 85:635-78
54. Boyer LA, Mathur D and Jaenisch R. Molecular control of pluripotency. Curr Opin Genet Dev. 2006; 16:455-62
55. Conboy IM and Rando TA. The regulation of Notch signaling controls satellite cell activation and cell fate determination in postnatal myogenesis. Dev.Cell. 2002; 3:397-409
56. Brack AS, Conboy IM, Conboy MJ, Shen J and Rando TA. A temporal switch from notch to Wnt signaling in muscle stem cells is necessary for normal adult myogenesis. Cell Stem Cell. 2008; 2:50-9
57. Jones SM and Kazlauskas A. Growth-factor-dependent mitogenesis requires two distinct phases of signalling. Nat Cell Biol. 2001; 3:165-72
58. Saunders LR, Sharma AD, Tawney J, Nakagawa M, Okita K, Yamanaka S, Willenbring H and Verdin E. miRNAs regulate SIRT1 expression during mouse embryonic stem cell differentiation and in adult mouse tissues. Aging (Albany NY). 2010; 2:415-31
59. Rahman S and Islam R. Mammalian Sirt1: insights on its biological functions. Cell Commun Signal. 2011; 9:11
60. Ratajczak MZ, Shin DM, Ratajczak J, Kucia M and Bartke A. A novel insight into aging: are there pluripotent very small embryonic-like stem cells (VSELs) in adult tissues overtime depleted in an Igf-1-dependent manner? Aging (Albany NY). 2010; 2:875-83
61. Bartke A. Single-gene mutations and healthy ageing in mammals. Philos Trans R Soc Lond B Biol Sci. 2011; 366:28-34
62. Kenyon C. The first long-lived mutants: discovery of the insulin/IGF-1 pathway for ageing. Philos Trans R Soc Lond B Biol Sci. 2011; 366:9-16.