Response to treatment with oral alitretinoin in patients with chronic hand eczema that is refractory to treatment with potent topical corticosteroids: Experience in 15 patients;Respuesta al tratamiento con alitretinoína oral en ECM refractario con eczema crónico de manos refractario al tratamiento con corticoides tópicos potentes: nuestra experiencia en 15 pacientes

Actas Dermo-Sifiliograficas

Volumn 102, Issue 8, 2011, Pages 616-622

  Aguayo Leiva, I R ^a   Urrutia, S ^a   Jaen Olasolo P ^a  

^a HOSPITAL RAMÓN Y CAJAL   (Spain)

Author keywords

Altitretinoin; Chronic hand eczema; Corticosteroids

Indexed keywords

ALITRETINOIN; CORTICOSTEROID;

ADULT; AGED; AMINOTRANSFERASE BLOOD LEVEL; ARTICLE; CHRONIC DISEASE; CLINICAL ARTICLE; CORTICOSTEROID THERAPY; DRUG EFFICACY; DRUG SAFETY; ECZEMA; EPIGASTRIC PAIN; FEMALE; HAND DISEASE; HAND ECZEMA; HEADACHE; HUMAN; LIPID BLOOD LEVEL; MALE; OBSERVATIONAL STUDY; PROSPECTIVE STUDY; SIDE EFFECT; THYROTROPIN BLOOD LEVEL; TREATMENT RESPONSE;

ADMINISTRATION, CUTANEOUS; ADMINISTRATION, ORAL; ADRENAL CORTEX HORMONES; ADULT; AGED; CHILD; CHRONIC DISEASE; DRUG RESISTANCE; ECZEMA; FEMALE; HAND DERMATOSES; HEADACHE; HUMANS; HYPERCHOLESTEROLEMIA; MIDDLE AGED; OCCUPATIONAL DISEASES; PROSPECTIVE STUDIES; THYROTROPIN; TREATMENT OUTCOME; TRETINOIN;

EID: 80052981967     PISSN: 00017310     EISSN: 15782190     Source Type: Journal    
DOI: 10.1016/j.ad.2010.10.012     Document Type: Article

References (23)

1. P.J. Coenraads, J.P. Nater, and R. van der Lende Prevalence of eczema and other dermatoses of the hands and arms in the Netherlands. Association with age and occupation Clin Exp Dermatol. 8 1983 495 503 (Pubitemid 13051900)
2. B. Meding, and B. Jarvholm Hand eczema in Swedish adults - changes in prevalence between 1983 and 1996 J Invest Dermatol. 118 2002 719 723 (Pubitemid 34309995)
3. J.F. Fowler, M.S. Duh, J. Chang, J. Person, D. Thorn, and M. Raut A survey-based assessment of the prevalence and severity of chronic hand dermatitis in a managed care organization Cutis. 77 2006 385 392 (Pubitemid 44032552)
4. E.A. Emmett Occupational contact dermatitis I: incidence and return to work pressures Am J Contact Dermatitis. 13 2002 30 34 (Pubitemid 34205626)
5. C. Rodríguez, and M. Ribera Tratamiento del eccema de las manos Piel. 24 2009 505 512
6. L.A. Drake, S.M. Dinehart, E.R. Farmer, R.W. Goltz, G.F. Graham, and M.K. Hordinsky Guidelines of care for the use of topical glucocorticosteroids J Am Acad Dermatol. 35 1996 615 619 (Pubitemid 26427069)
7. C. Schnopp, R. Remling, M. Möhrenschlager, L. Weigl, J. Ring, and D. Abeck Topical tacrolimus (FK506) and mometasone furoate in treatment of dyshidrotic palmar eczema: a randomized, observer-blinded trial J Am Acad Dermatol. 46 2002 73 77 (Pubitemid 34073481)
8. J.M. Hanifin, V. Stevens, P. Sheth, and D. Breneman Novel treatment of chronic severe hand dermatitis with bexarotene gel Br J Dermatol. 150 2004 545 553 (Pubitemid 38446312)
9. U. Wollina, and T. Karamfilov Adjuvant botulinum toxin A in dyshidrotic hand eczema: a controlled prospective pilot study with left-right comparison J Eur Acad Dermatol Venereol. 16 2002 40 42 (Pubitemid 34202001)
10. R. Schiener, P. Gottlober, B. Muller, S. Williams, H. Pillekamp, and R.U. Peter PUVA-gel vs. PUVA-bath therapy for severe recalcitrant palmoplantar dermatoses. A randomized, single-blinded prospective study Photodermatol Photoimmunol Photomed. 21 2005 62 67 (Pubitemid 40425648)
11. H. Granlund, P. Erkko, E. Eriksson, and S. Reitamo Comparison of cyclosporine and topical betamethasone-17,21-dipropionate in the treatment of severe chronic hand eczema Acta Derm Venereol. 76 1996 371 376 (Pubitemid 26297982)
12. C.A. Egan, T.M. Rallis, K.P. Meadows, and G.G. Krueger Low-dose oral methotrexate treatment for recalcitrant palmoplantar pompholyx J Am Acad Dermatol. 40 1999 612 614 (Pubitemid 29153192)
13. A. Pickenäcker, T.A. Luger, and T. Schwarz Dyshidrotic eczema treated with mycophenolatemofetil Arch Dermatol. 134 1998 378 379
14. N.K. Veien, and T. Menne Treatment of hand eczema Skin Therapy Lett. 8 2003 4 7
15. J.M. Mascaró, I. Querol-Nasarre, L. Lindner, M. Prior, J. Oliver, and R. Halbach Impacto de la introducción de alitretinoína oral en los costes del eczema de las manos severo de origen profesional desde la perspectiva de las mutuas de accidente de trabajo y enfermedades profesionales en Espana Rev SEMST. 5 2010 9 18
16. A.M. Van Coevorden, P.J. Coenraads, A. Svensson, J.N. Bavinck, T.L. Diepgen, and L. Naldi Overview of studies of treatments for hand eczema-the EDEN hand eczema survey Br J Dermatol. 151 2004 446 451 (Pubitemid 39215159)
17. W. Bollag, and F. Ott Successful treatment of chronic hand eczema with oral 9-cis-retinoic acid Dermatology. 199 1999 308 312 (Pubitemid 30009040)
18. T. Ruzicka, F.G. Larsen, D. Galewicz, A. Horva'th, P.J. Coenraads, and K. Thestrup-Pedersen Oral alitretinoin (9-cis-retinoic acid) therapy for chronic hand dermatitis in patients refractory to standard therapy: results of a randomized, double-blind, placebocontrolled, multicenter trial Arch Dermatol. 140 2004 1453 1459 (Pubitemid 39627436)
19. T. Ruzicka, C.W. Lynde, G.B. Jemec, T. Diepgen, J. Berth-Jones, and P.J. Coenraads Efficacy and safety of oral alitretinoin (9-cis retinoic acid) in patients with severe chronic hand eczema refractory to topical corticosteroids: results of a randomized, double-blind, placebo-controlled, multicentre trial Br J Dermatol. 158 2008 808 817 (Pubitemid 351415754)
20. R. Bissonnette, M. Worm, B. Gerlach, L. Guenther, F. Cambazard, and T. Ruzicka Successful retreatment with alitretinoin in patients with relapsed chronic hand eczema Br J Dermatol. 162 2010 420 426
21. P.R. Blank, A.A. Blank, and T.D. Szucs Cost-effectiveness of oral alitretinoin in patients with severe chronic hand eczema - a long-term analysis from a Swiss perspective BMC Dermatol. 10 2010 4
22. A. Alomar, J.M. Fernández Vozmediano, E. Serra, and P. Manrique Allitretinoin and chronic eczema of hands Med Cutan Iber Lat Am. 38 2010 23 32
23. C. Cheng, J. Michaels, and N. Scheinfeld Alitretinoin: a comprehensive review Expert Opin Investig Drugs. 17 2008 437 443