Nitrous oxide by itself is insufficient to relieve pain due to castration in piglets

Journal of Animal Science

Volumn 89, Issue 10, 2011, Pages 3318-3325

  Rault, J L ^a   Lay Jr , D C ^b  

^a PURDUE UNIVERSITY   (United States)

^b U S DEPARTMENT OF AGRICULTURE   (United States)

Author keywords

Analgesic; Anesthetic; Castration; Gas; Nitrous oxide; Piglet

Indexed keywords

INHALATION ANESTHETIC AGENT; NITROUS OXIDE;

ANIMAL; ANIMAL DISEASE; ARTICLE; MALE; NEWBORN; ORCHIECTOMY; PAIN; SWINE;

ANESTHETICS, INHALATION; ANIMALS; ANIMALS, NEWBORN; MALE; NITROUS OXIDE; ORCHIECTOMY; PAIN; SWINE;

ANIMALIA;

EID: 80052980163     PISSN: 00218812     EISSN: 15253163     Source Type: Journal    
DOI: 10.2527/jas.2011-4104     Document Type: Article

References (24)

1. American Veterinary Medical Association. 2007. American Veterinary Medical Association Guidelines on Euthanasia. Accessed May 22, 2010. http://www.avma.org/issues/animal_welfare/euthanasia.pdf.
2. Clark, M., and A. Brunick. 2003. Handbook of Nitrous Oxide and Oxygen Sedation. 2nd ed. Mosby Inc., St. Louis, MO.
3. FASS. 2010. Guide for the Care and Use of Agricultural Animals in Research and Teaching. 3rd ed. Fed. Anim. Sci. Soc., Savoy, IL.
4. Fujinaga, M., and M. Maze. 2002. Neurobiology of nitrous oxideinduced antinociceptive effects. Mol. Neurobiol. 25:167-189.
5. Gerritzen, M. A., M. Kluivers-Poodt, H. G. M. Reimert, V. Hindle, and E. Lambooij. 2008. Castration of piglets under CO2-gas anaesthesia. Animal 2:1666-1673.
6. Hay, M., A. Vulin, S. Génin, P. Sales, and A. Prunier. 2003. Assessment of pain induced by castration in piglets: Behavioural and physiological responses over the subsequent 5 days. Appl. Anim. Behav. Sci. 82:201-218.
7. Kanagasundaram, S. A., L. J. Lane, B. P. Cavalletto, J. P. Keneally, and M. G. Cooper. 2001. Efficacy and safety of nitrous oxide in alleviating pain and anxiety during painful procedures. Arch. Dis. Child. 84:492-495.
8. Kohler, I., Y. Moens, A. Busato, J. Blum, and U. Schatzmann. 1998. Inhalation anaesthesia for the castration of piglets: CO2 compared to halothane. Zentralbl. Veterinarmed. A 45:625-633.
9. Leidig, M. S., B. Hertrampf, K. Failing, A. Schumann, and G. Reiner. 2009. Pain and discomfort in male piglets during surgical castration with and without local anaesthesia as determined by vocalization and defence behavior. Appl. Anim. Behav. Sci. 116:174-178.
10. Louie, K., and M. A. Wilson. 2001. Temporally structured replay of awake hippocampal ensemble activity during rapid eye movement sleep. Neuron 29:145-156.
11. Lundstrom, K., K. R. Matthews, and J. E. Haugen. 2009. Pig meat quality from entire males. Animal 3:1497-1507.
12. Marchant-Forde, J. N., D. C. Lay Jr., K. A. McMunn, H. W. Cheng, E. A. Pajor, and R. M. Marchant-Forde. 2009. Postnatal piglet husbandry practices and well-being: The effects of alternative techniques delivered separately. J. Anim. Sci. 87:1479-1492.
13. Marx, G., T. Horn, J. Thielebein, B. Knubel, and E. von Borell. 2003. Analysis of pain-related vocalization in young pigs. J. Sound Vibrat. 266:687-698.
14. McGlone, J. J., and J. M. Hellman. 1988. Local and general anesthetic effects on behavior and performance of two- and seven-week-old castrated and uncastrated piglets. J. Anim. Sci. 66:3049-3058.
15. McGlone, J. J., R. I. Nicholson, J. M. Hellman, and D. N. Herzog. 1993. The development of pain in young pigs associated with castration and attempts to prevent castration-induced behavioral changes. J. Anim. Sci. 71:1441-1446.
16. Moya, S. L., L. A. Boyle, P. B. Lynch, and S. Arkins. 2008. Effect of surgical castration on the behavioural and acute phase responses of 5-day-old piglets. Appl. Anim. Behav. Sci. 111:133-145.
17. Neff, W., E. C. Mayer, and M. De La Luz Perales. 1947. Nitrous oxide and oxygen anesthesia with curare relaxation. Calif. Med. 66:67-69.
18. Puppe, B., P. C. Schön, A. Tuchscherer, and G. Manteuffel. 2005. Castration-induced vocalization in domestic piglets, Sus scrofa: Complex and specific alterations of the vocal quality. Appl. Anim. Behav. Sci. 95:67-78.
19. Rault, J.-L., D. C. Lay Jr., and J. N. Marchant-Forde. 2011. Castration-induced pain in pigs and other livestock. Appl. Anim. Behav. Sci. In press.
20. Rydhmer, L., K. Lundstrom, and K. Andersson. 2010. Immunocastration reduces aggressive and sexual behaviour in male pigs. Animal 4:965-972.
21. Taylor, A. A., and D. M. Weary. 2000. Vocal responses of piglets to castration: Identifying procedural sources of pain. Appl. Anim. Behav. Sci. 70:17-26.
22. 2O. J. Vet. Med. A 51:150-154.
23. Weary, D. M., L. A. Braithwaite, and D. Fraser. 1998. Vocal response to pain in piglets. Appl. Anim. Behav. Sci. 56:161-172.
24. White, R. G., J. A. DeShazer, C. J. Tressler, G. M. Borcher, S. Davey, A. Waninge, A. M. Parkhurst, M. J. Milanuk, and E. T. Clemens. 1995. Vocalization and physiological response of pigs during castration with or without a local anesthetic. J. Anim. Sci. 73:381-386.