A preliminary investigation of the reinnervation and return of sensory function in burn patients treated with INTEGRA®

Burns

Volumn 37, Issue 7, 2011, Pages 1101-1108

  Anderson, James R ^a,b   Fear, Mark W ^a,c   Phillips, Jacqueline K ^d   Dawson, Linda F ^e   Wallace, Hilary ^b   Wood, Fiona M ^a,b,f   Rea, Suzanne M ^a,b,f  

^a ROYAL PERTH HOSPITAL   (Australia)

^b UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^c UNIVERSITY OF NOTRE DAME   (Australia)

^d MACQUARIE UNIVERSITY   (Australia)

^e MURDOCH UNIVERSITY   (Australia)

^f PRINCESS MARGARET HOSPITAL FOR CHILDREN   (Australia)

Author keywords

Burn injury; INTEGRA; Nerves; Sensory function; Skin

Indexed keywords

BIOLOGICAL MARKER; CALCITONIN GENE RELATED PEPTIDE; SUBSTANCE P;

ADULT; ARTICLE; BURN; BURN DRESSING; BURN PATIENT; CLINICAL ARTICLE; COMPOSITE SKIN GRAFT; HUMAN; IMMUNOHISTOCHEMISTRY; NERVE FIBER GROWTH; NERVE GROWTH; NEUROANATOMY; PERIPHERAL NERVE; REINNERVATION; SENSORY SYSTEM; SPLIT THICKNESS SKIN GRAFT; STATISTICAL SIGNIFICANCE; TREATMENT OUTCOME;

ADULT; BURNS; CELLS, CULTURED; CHONDROITIN SULFATES; CICATRIX; COLLAGEN; EPITHELIUM; HUMANS; IMMUNOHISTOCHEMISTRY; NERVE REGENERATION; PERIPHERAL NERVES; RECOVERY OF FUNCTION; SENSORY THRESHOLDS; SKIN; SKIN TRANSPLANTATION; TOUCH PERCEPTION; WOUND HEALING;

EID: 80052971026     PISSN: 03054179     EISSN: 18791409     Source Type: Journal    
DOI: 10.1016/j.burns.2011.04.002     Document Type: Article

References (23)

1. M. Mihara Regenerated cutaneous nerves in human epidermal and subepidermal regions. An electron microscopy study Arch Dermatol Res 276 2 1984 115 122 (Pubitemid 14154262)
2. V. Altun, T.E. Hakvoort, P.P. van Zuijlen, T.H. van der Kwast, and E.P. Prens Nerve outgrowth and neuropeptide expression during the remodeling of human burn wound scars. A 7-month follow-up study of 22 patients Burns 27 7 2001 717 722 (Pubitemid 32910616)
3. B. Nedelec, Q. Hou, I. Sohbi, M. Choiniere, G. Beauregard, and R.W. Dykes Sensory perception and neuroanatomical structures in normal and grafted skin of burn survivors Burns 31 2005 817 830 (Pubitemid 41394137)
4. R.S. Ward, R.P. Tuckett, K.B. English, O. Johansson, and J.R. Saffle Substance P axons and sensory threshold increase in burn-graft human skin J Surg Res 118 2004 154 160 (Pubitemid 38501716)
5. M. Stella, M. Calcagni, S. Teich-Alasia, G. Ramieri, G. Cellino, and G. Panzica Sensory endings in skin grafts and scars after extensive burns Burns 20 6 1994 491 495 (Pubitemid 24373270)
6. J.R. Anderson, J.S. Zorbas, J.K. Phillips, J.L. Harrison, L.F. Dawson, and S.E. Bolt Systemic decreases in cutaneous innervation after burn injury J Invest Dermatol 2010 [Epub ahead of print] March 25
7. A. Malenfant, R. Forget, R. Amsel, J. Papillon, J.Y. Frigon, and M. Choiniere Tactile, thermal and pain sensibility in burned patients with and without chronic pain and paresthesia problems Pain 77 1998 241 251 (Pubitemid 28451512)
8. A. Hermanson, C.J. Dalsgaard, H. Bjorklund, and U. Lindblom Sensory reinnervation and sensibility after superficial skin wounds in human patients Neurosci Lett 74 1987 377 382 (Pubitemid 17017973)
9. R. Stern, M. McPherson, and M.T. Longaker Histologic study of artificial skin used in the treatment of full-thickness thermal injury J Burn Care Rehabil 11 1990 7 13 (Pubitemid 20097560)
10. N.S. Moiemen, J.J. Staiano, N.O. Ojeh, Y. Thway, and J.D. Frame Reconstructive surgery with a dermal regeneration template: clinical and histologic study Plast Reconstr Surg 108 1 2001 93 103 (Pubitemid 32587029)
11. I.N. Day, and R.J. Thompson UCHL1 (PGP 9.5): neuronal biomarker and ubiquitin system protein Prog Neurobiol 90 3 2010 327 362
12. M. Zaidi, B.S. Moonga, P.J. Bevis, Z.A. Bascal, and L.H. Breimer The calcitonin gene peptides: biology and clinical relevance Crit Rev Clin Lab Sci 28 2 1990 109 174
13. J.W. Griffin, and P Polydefkis Assessment of cutaneous innervation by skin biopsies Curr Opin Neurol 14 5 2001 655 659 (Pubitemid 32964587)
14. F.M. Wood, M.L. Kolybaba, and P. Allen The use of cultured epithelial autograft in the treatment of major burn wounds: eleven years of clinical experience Burns 32 August 5 2006 538 544
15. Rasband WS, ImageJ. Edited by U.S. National Institutes of Health, Bethesda, MD, USA, 2007; http://rsbinfonihgov/ij/.
16. M.J. Baryza, and G.A. Baryza The Vancouver scar scale: an administration tool and its interrater reliability J Burn Care Rehabil 16 5 1995 535 538
17. I.V. Yannas, J.F. Burke, P.L. Gordon, C. Huang, and R.H. Rubenstein Design of an artificial skin, II. Control of chemical composition J Biomed Mater Res 14 1980 107 131 (Pubitemid 10132084)
18. J.F. Burke, I.V. Yannas, W.C. Quinby Jr., C.C. Bondoc, and W.K. Jung Successful use of a physiologically acceptable artificial skin in the treatment of extensive burn injury Ann Surg 194 1981 413 428
19. D. Heimbach, A. Luterman, J. Burke, A. Cram, D. Herndon, and J. Hunt Artificial dermis for major burns. A multi-center randomized clinical trial Ann Surg 208 3 1988 313 320
20. A. Malenfant, R. Forget, J. Papillon, R. Amsel, J.Y. Frigon, and M. Choiniere Prevalence and characteristics of chronic sensory problems in burn patients Pain 67 2-3 1996 493 500 (Pubitemid 26375367)
21. Z.L. Chen, W.M. Yu, and S. Strickland Peripheral regeneration Annu Rev Neurosci 30 2007 209 233 (Pubitemid 47218756)
22. L.N. Gillespie Regulation of axonal growth and guidance by the neurotrophin family of neurotrophic factors Clin Exp Pharmacol Physiol 30 October 10 2003 724 733 (Pubitemid 37330518)
23. T. Carlstedt Approaches permitting enhancing motoneuron regeneration after spinal cord, ventral root, plexus and peripheral nerve injuries Curr Opin Neurol 13 December 6 2000 683 686 (Pubitemid 32002652)