Ex vivo demonstration of a synergistic effect of Adapalene and benzoyl peroxide on inflammatory acne lesions

Experimental Dermatology

Volumn 20, Issue 10, 2011, Pages 850-853

  Zuliani, Thomas ^a   Khammari, Amir ^a,b   Chaussy, Hélène ^b   Knol, Anne Chantal ^a   Dréno, Brigitte ^a,b  

^a INSERM   (France)

^b NANTES UNIVERSITY HOSPITAL   (France)

Author keywords

Acne; Adapalene; Benzoyl peroxide; Epidermal proliferation differentiation; Innate immunity

Indexed keywords

ADAPALENE; ALPHA2 INTEGRIN; ALPHA3 INTEGRIN; ALPHA6 INTEGRIN; BENZOYL PEROXIDE; BETA DEFENSIN 4; INTERLEUKIN 8; KI 67 ANTIGEN; TOLL LIKE RECEPTOR 2;

ACNE; CELL DIFFERENTIATION; CELL PROLIFERATION; CLINICAL ARTICLE; DRUG POTENTIATION; EX VIVO STUDY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INNATE IMMUNITY; KERATINOCYTE; LETTER; PROTEIN EXPRESSION;

ACNE VULGARIS; ADULT; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BENZOYL PEROXIDE; BETA-DEFENSINS; CELL DIFFERENTIATION; CELL PROLIFERATION; DERMATOLOGIC AGENTS; DRUG SYNERGISM; DRUG THERAPY, COMBINATION; FEMALE; HUMANS; IMMUNITY, INNATE; IMMUNOHISTOCHEMISTRY; INTEGRINS; MALE; NAPHTHALENES; YOUNG ADULT;

EID: 80052969838     PISSN: 09066705     EISSN: 16000625     Source Type: Journal    
DOI: 10.1111/j.1600-0625.2011.01339.x     Document Type: Letter

References (18)

1. Pawin H, Beylot C, Chivot M et al. Eur J Dermatol 2004: 14: 4-12.
2. Kurokawa I, Danby F W, Ju Q et al. Exp Dermatol 2009: 18: 821-832.
3. Loesche C, Pernin C, Poncet M. Eur J Dermatol 2008: 18: 524-526.
4. Jeremy A H, Holland D B, Roberts S G et al. J Invest Dermatol 2003: 121: 20-27.
5. Nagy I, Pivarcsi A, Koreck A et al. J Invest Dermatol 2005: 124: 931-938.
6. Kim J, Ochoa M T, Krutzik S R et al. J Immunol 2002: 169: 1535-1541.
7. Sugisaki H, Yamanaka K, Kakeda M et al. J Dermatol Sci 2009: 55: 47-52.
8. Tenaud I, Khammari A, Dreno B. Exp Dermatol 2007: 16: 500-506.
9. Fakhouri T, Yentzer B A, Feldman S R. J Drugs Dermatol 2009: 8: 657-661.
10. Russell J J. Am Fam Physician 2000: 61: 357-366.
11. Thiboutot D M, Weiss J, Bucko A et al. J Am Acad Dermatol 2007: 57: 791-799.
12. Gold L S, Cruz A, Eichenfield L et al. Cutis 2010: 85: 94-104.
13. Tan J, Gollnick H P, Loesche C et al. J Dermatolog Treat 2010: 22: 197-205.
14. Cunliffe W J, Holland D B, Clark S M et al. Br J Dermatol 2000: 142: 1084-1091.
15. Knaggs H E, Holland D B, Morris C et al. J Invest Dermatol 1994: 102: 89-92.
16. Tanghetti E, Kircik L, Wilson D et al. J Drugs Dermatol 2008: 7: 534-538.
17. Graham G M, Farrar M D, Cruse-Sawyer J E et al. Br J Dermatol 2004: 150: 421-428.
18. Niyonsaba F, Ushio H, Nakano N et al. J Invest Dermatol 2007: 127: 594-604.