A framework for in-silico formulation design using multivariate latent variable regression methods

International Journal of Pharmaceutics

Volumn 418, Issue 2, 2011, Pages 235-242

  Polizzi, Mark A ^a   García Muñoz, Salvador ^a  

^a PFIZER INC   (United States)

Author keywords

Blending; Mixture modeling; PCA; PLS

Indexed keywords

DRUG;

ARTICLE; COMPUTER MODEL; DRUG DESIGN; DRUG FORMULATION; PARTIAL LEAST SQUARES REGRESSION; PARTICLE SIZE; POWDER; PREDICTION; PRINCIPAL COMPONENT ANALYSIS; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REGRESSION ANALYSIS; SCORING SYSTEM; VALIDATION PROCESS;

COMPUTER SIMULATION; DATABASES, FACTUAL; DRUG COMPOUNDING; DRUG DESIGN; MULTIVARIATE ANALYSIS; PHARMACEUTICAL PREPARATIONS; REPRODUCIBILITY OF RESULTS;

EID: 80052968375     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2011.04.064     Document Type: Article

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