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Volumn 55, Issue 4, 2011, Pages 858-865

Dynamic contrast-enhanced magnetic resonance imaging biomarkers predict survival and response in hepatocellular carcinoma patients treated with sorafenib and metronomic tegafur/uracil

Author keywords

Metronomic chemotherapy; Sorafenib; Tegafur uracil; Vascular response

Indexed keywords

SORAFENIB; UFT;

EID: 80052948925     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2011.01.032     Document Type: Article
Times cited : (107)

References (38)
  • 2
    • 57749189578 scopus 로고    scopus 로고
    • Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: A phase III randomised, double-blind, placebo-controlled trial
    • A.L. Cheng, Y.K. Kang, Z. Chen, C.J. Tsao, S. Qin, and J.S. Kim Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, double-blind, placebo-controlled trial Lancet Oncol 10 2009 25 34
    • (2009) Lancet Oncol , vol.10 , pp. 25-34
    • Cheng, A.L.1    Kang, Y.K.2    Chen, Z.3    Tsao, C.J.4    Qin, S.5    Kim, J.S.6
  • 4
    • 16544380415 scopus 로고    scopus 로고
    • Phase II studies of modern drugs directed against new targets: If you are fazed, too, then resist RECIST
    • DOI 10.1200/JCO.2004.07.960
    • M.J. Ratain, and G. Eckhardt Phase II studies of modern drugs directed against new targets: if you are fazed too, then resist RECIST J Clin Oncol 22 2004 4442 4445 (Pubitemid 41185107)
    • (2004) Journal of Clinical Oncology , vol.22 , Issue.22 , pp. 4442-4445
    • Ratain, M.J.1    Eckhardt, S.G.2
  • 5
    • 84984578313 scopus 로고    scopus 로고
    • Efficacy and tolerability of bevacizumab plus capecitabine as first-line therapy in patients with advanced hepatocellular carcinoma
    • C.H. Hsu, T.S. Yang, C. Hsu, H.C. Toh, R.J. Epstein, and L.T. Hsiao Efficacy and tolerability of bevacizumab plus capecitabine as first-line therapy in patients with advanced hepatocellular carcinoma Br J Cancer 102 2010 981 986
    • (2010) Br J Cancer , vol.102 , pp. 981-986
    • Hsu, C.H.1    Yang, T.S.2    Hsu, C.3    Toh, H.C.4    Epstein, R.J.5    Hsiao, L.T.6
  • 6
    • 77953124105 scopus 로고    scopus 로고
    • Phase II study of combining sorafenib with metronomic tegafur/uracil for advanced hepatocellular carcinoma
    • C.H. Hsu, Y.C. Shen, Z.Z. Lin, P.J. Chen, Y.Y. Shao, and Y.H. Ding Phase II study of combining sorafenib with metronomic tegafur/uracil for advanced hepatocellular carcinoma J Hepatol 53 2010 126 131
    • (2010) J Hepatol , vol.53 , pp. 126-131
    • Hsu, C.H.1    Shen, Y.C.2    Lin, Z.Z.3    Chen, P.J.4    Shao, Y.Y.5    Ding, Y.H.6
  • 7
    • 2942615257 scopus 로고    scopus 로고
    • The anti-angiogenic basis of metronomic chemotherapy
    • R.S. Kerbel, and B.A. Kamen The anti-angiogenic basis of metronomic chemotherapy Nat Rev Cancer 4 2004 423 436 (Pubitemid 38745528)
    • (2004) Nature Reviews Cancer , vol.4 , Issue.6 , pp. 423-436
    • Kerbel, R.S.1    Kamen, B.A.2
  • 8
    • 33846212284 scopus 로고    scopus 로고
    • Sorafenib blocks the RAF/MEK/ERK pathway, inhibits tumor angiogenesis, and induces tumor cell apoptosis in hepatocellular carcinoma model PLC/PRF/5
    • DOI 10.1158/0008-5472.CAN-06-1377
    • L. Liu, Y. Cao, C. Chen, X. Zhang, A. McNabola, and D. Wilkie Sorafenib blocks the RAF/MEK/ERK pathway, inhibits tumor angiogenesis, and induces tumor cell apoptosis in hepatocellular carcinoma model PLC/PRF/5 Cancer Res 66 2006 11851 11858 (Pubitemid 46094197)
    • (2006) Cancer Research , vol.66 , Issue.24 , pp. 11851-11858
    • Liu, L.1    Cao, Y.2    Chen, C.3    Zhang, X.4    McNabola, A.5    Wilkie, D.6    Wilhelm, S.7    Lynch, M.8    Carter, C.9
  • 9
    • 44749089874 scopus 로고    scopus 로고
    • Molecular targeted therapies in hepatocellular carcinoma: From pre-clinical models to clinical trials
    • P. Newell, A. Villanueva, and J.M. Llovet Molecular targeted therapies in hepatocellular carcinoma: from pre-clinical models to clinical trials J Hepatol 49 2008 1 5
    • (2008) J Hepatol , vol.49 , pp. 1-5
    • Newell, P.1    Villanueva, A.2    Llovet, J.M.3
  • 12
    • 33846478656 scopus 로고    scopus 로고
    • DCE-MRI biomarkers in the clinical evaluation of antiangiogenic and vascular disrupting agents
    • DOI 10.1038/sj.bjc.6603515, PII 6603515
    • J.P.B. O'Connor, A. Jackson, G.J.M. Parker, and G.C. Jayson DCE-MRI biomarkers in the clinical evaluation of antiangiogenic and vascular disrupting agents Br J Cancer 96 2007 189 195 (Pubitemid 46160619)
    • (2007) British Journal of Cancer , vol.96 , Issue.2 , pp. 189-195
    • O'Connor, J.P.B.1    Jackson, A.2    Parker, G.J.M.3    Jayson, G.C.4
  • 14
    • 23844456531 scopus 로고    scopus 로고
    • Expanding the use of magnetic resonance in the assessment of tumor response to therapy: Workshop report
    • DOI 10.1158/0008-5472.CAN-05-0674
    • J. Evelhoch, M. Garwood, D. Vigneron, M. Knopp, D. Sullivan, and A. Menkens Expanding the use of magnetic resonance in the assessment of tumor response to therapy: workshop report Cancer Res 65 2005 7041 7044 (Pubitemid 41161229)
    • (2005) Cancer Research , vol.65 , Issue.16 , pp. 7041-7044
    • Evelhoch, J.1    Garwood, M.2    Vigneron, D.3    Knopp, M.4    Sullivan, D.5    Menkens, A.6    Clarke, L.7    Liu, G.8
  • 15
    • 0032853898 scopus 로고    scopus 로고
    • Key factors in the acquisition of contrast kinetic data for oncology
    • DOI 10.1002/(SICI)1522-2586(199909)10:3<254::AID-JMRI5>3.0.CO;2-9
    • J.L. Evelhoch Key factors in the acquisition of contrast kinetic data for oncology J Magn Reson Imaging 10 1999 254 259 (Pubitemid 29463107)
    • (1999) Journal of Magnetic Resonance Imaging , vol.10 , Issue.3 , pp. 254-259
    • Evelhoch, J.L.1
  • 16
    • 59449089100 scopus 로고    scopus 로고
    • Phase 2 open-label study of single-agent sorafenib in treating advanced hepatocellular carcinoma in a hepatitis B-endemic Asian population: Presence of lung metastasis predicts poor response
    • T. Yau, P. Chan, K.K. Ng, S.H. Chok, T.T. Cheung, and S.T. Fan Phase 2 open-label study of single-agent sorafenib in treating advanced hepatocellular carcinoma in a hepatitis B-endemic Asian population: presence of lung metastasis predicts poor response Cancer 115 2009 428 436
    • (2009) Cancer , vol.115 , pp. 428-436
    • Yau, T.1    Chan, P.2    Ng, K.K.3    Chok, S.H.4    Cheung, T.T.5    Fan, S.T.6
  • 17
    • 34247857540 scopus 로고    scopus 로고
    • Safety, pharmacokinetics, and preliminary antitumor activity of sorafenib: A review of four phase I trials in patients with advanced refractory solid tumors
    • DOI 10.1634/theoncologist.12-4-426
    • D. Strumberg, J.W. Clark, A. Awada, M.J. Moore, H. Richly, and A. Hendlisz Safety, pharmacokinetics, and preliminary antitumor activity of sorafenib: a review of four phase I trials in patients with advanced refractory solid tumors Oncologist 12 2007 426 437 (Pubitemid 46698720)
    • (2007) Oncologist , vol.12 , Issue.4 , pp. 426-437
    • Strumberg, D.1    Clark, J.W.2    Awada, A.3    Moore, M.J.4    Richly, H.5    Hendlisz, A.6    Hirte, H.W.7    Eder, J.P.8    Lenz, H.-J.9    Schwartzh, B.10
  • 18
    • 0031750330 scopus 로고    scopus 로고
    • UFT plus oral leucovorin: A new oral treatment for colorectal cancer
    • P.M. Hoff, and R. Pazdur UFT plus oral leucovorin: a new oral treatment for colorectal cancer Oncologist 3 1998 155 164 (Pubitemid 28307446)
    • (1998) Oncologist , vol.3 , Issue.3 , pp. 155-164
    • Hoff, P.M.1    Pazdur, R.2
  • 22
    • 33645665698 scopus 로고    scopus 로고
    • Comparative study into the robustness of compartmental modeling and model-free analysis in DCE-MRI studies
    • C. Roberts, B. Issa, A. Stone, A. Jackson, J.C. Waterton, and G.J. Parker Comparative study into the robustness of compartmental modeling and model-free analysis in DCE-MRI studies J Magn Reson Imaging 23 2006 554 563
    • (2006) J Magn Reson Imaging , vol.23 , pp. 554-563
    • Roberts, C.1    Issa, B.2    Stone, A.3    Jackson, A.4    Waterton, J.C.5    Parker, G.J.6
  • 23
    • 77957559384 scopus 로고    scopus 로고
    • Early alpha-fetoprotein response predicts treatment efficacy of anti-angiogenic systemic therapy in patients with advanced hepatocellular carcinoma
    • Y.Y. Shao, Z.Z. Lin, C. Hsu, Y.C. Shen, C.H. Hsu, and A.L. Cheng Early alpha-fetoprotein response predicts treatment efficacy of anti-angiogenic systemic therapy in patients with advanced hepatocellular carcinoma Cancer 116 2010 4590 4596
    • (2010) Cancer , vol.116 , pp. 4590-4596
    • Shao, Y.Y.1    Lin, Z.Z.2    Hsu, C.3    Shen, Y.C.4    Hsu, C.H.5    Cheng, A.L.6
  • 24
    • 74749099130 scopus 로고    scopus 로고
    • Assessing tumor response and detecting recurrence in metastatic renal cell carcinoma on targeted therapy: Importance of size and attenuation on contrast-enhanced CT
    • A.D. Smith, M.L. Lieber, and S.N. Shah Assessing tumor response and detecting recurrence in metastatic renal cell carcinoma on targeted therapy: importance of size and attenuation on contrast-enhanced CT AJR Am J Roentgenol 194 2010 157 165
    • (2010) AJR Am J Roentgenol , vol.194 , pp. 157-165
    • Smith, A.D.1    Lieber, M.L.2    Shah, S.N.3
  • 25
    • 33748976883 scopus 로고    scopus 로고
    • To predict progression-free survival and overall survival in metastatic renal cancer treated with sorafenib: Pilot study using dynamic contrast-enhanced Doppler ultrasound
    • DOI 10.1016/j.ejca.2006.04.023, PII S0959804906006071
    • M. Lamuraglia, B. Escudier, L. Chami, B. Schwartz, J. Leclre, and A. Roche To predict progression-free survival and overall survival in metastatic renal cancer treated with sorafenib: pilot study using dynamic contrast-enhanced Doppler ultrasound Eur J Cancer 42 2006 2472 2479 (Pubitemid 44442955)
    • (2006) European Journal of Cancer , vol.42 , Issue.15 , pp. 2472-2479
    • Lamuraglia, M.1    Escudier, B.2    Chami, L.3    Schwartz, B.4    Leclere, J.5    Roche, A.6    Lassau, N.7
  • 26
    • 78650627466 scopus 로고    scopus 로고
    • Advanced hepatocellular carcinoma: Early evaluation of response to bevacizumab therapy at dynamic contrast-enhanced US with quantification - Preliminary results
    • N. Lassau, S. Koscielny, L. Chami, M. Chebil, B. Benatsou, and A. Roche Advanced hepatocellular carcinoma: early evaluation of response to bevacizumab therapy at dynamic contrast-enhanced US with quantification - preliminary results Radiology 258 2011 291 300
    • (2011) Radiology , vol.258 , pp. 291-300
    • Lassau, N.1    Koscielny, S.2    Chami, L.3    Chebil, M.4    Benatsou, B.5    Roche, A.6
  • 27
    • 53749092242 scopus 로고    scopus 로고
    • Dynamic contrast-enhanced magnetic resonance imaging pharmacodynamic biomarker study of sorafenib in metastatic renal carcinoma
    • O.M. Hahn, C. Yang, M. Medved, G. Karczmar, E. Kistner, and T. Karrison Dynamic contrast-enhanced magnetic resonance imaging pharmacodynamic biomarker study of sorafenib in metastatic renal carcinoma J Clin Oncol 26 2008 4572 4578
    • (2008) J Clin Oncol , vol.26 , pp. 4572-4578
    • Hahn, O.M.1    Yang, C.2    Medved, M.3    Karczmar, G.4    Kistner, E.5    Karrison, T.6
  • 29
    • 77952468875 scopus 로고    scopus 로고
    • Phase II clinical trial of sorafenib in metastatic medullary thyroid cancer
    • E.T. Lam, M.D. Ringel, R.T. Kloos, T.W. Prior, M.V. Knopp, and J. Liang Phase II clinical trial of sorafenib in metastatic medullary thyroid cancer J Clin Oncol 28 2010 2323 2330
    • (2010) J Clin Oncol , vol.28 , pp. 2323-2330
    • Lam, E.T.1    Ringel, M.D.2    Kloos, R.T.3    Prior, T.W.4    Knopp, M.V.5    Liang, J.6
  • 31
    • 67649946279 scopus 로고    scopus 로고
    • Efficacy, safety, and potential biomarkers of sunitinib monotherapy in advanced hepatocellular carcinoma: A phase II study
    • A.X. Zhu, D.V. Sahani, D.G. Duda, E. di Tomaso, M. Ancukiewicz, and O.A. Catalano Efficacy, safety, and potential biomarkers of sunitinib monotherapy in advanced hepatocellular carcinoma: a phase II study J Clin Oncol 27 2009 3027 3035
    • (2009) J Clin Oncol , vol.27 , pp. 3027-3035
    • Zhu, A.X.1    Sahani, D.V.2    Duda, D.G.3    Di Tomaso, E.4    Ancukiewicz, M.5    Catalano, O.A.6
  • 34
    • 70350721785 scopus 로고    scopus 로고
    • Quantifying antivascular effects of monoclonal antibodies to vascular endothelial growth factor: Insights from imaging
    • J.P.B. O'Connor, R.A.D. Carano, A.R. Clamp, J. Ross, C.C.K. Ho, and A. Jackson Quantifying antivascular effects of monoclonal antibodies to vascular endothelial growth factor: insights from imaging Clin Cancer Res 15 2009 6674 6682
    • (2009) Clin Cancer Res , vol.15 , pp. 6674-6682
    • O'Connor, J.P.B.1    Carano, R.A.D.2    Clamp, A.R.3    Ross, J.4    Ho, C.C.K.5    Jackson, A.6
  • 35
    • 33845970553 scopus 로고    scopus 로고
    • Tracking Normalization of Brain Tumor Vasculature by Magnetic Imaging and Proangiogenic Biomarkers
    • DOI 10.1016/j.ccr.2006.12.008, PII S1535610806003758
    • A. Hormigo, P.H. Gutin, and S. Rafii Tracking normalization of brain tumor vasculature by magnetic Imaging and proangiogenic biomarkers Cancer Cell 11 2007 6 8 (Pubitemid 46054523)
    • (2007) Cancer Cell , vol.11 , Issue.1 , pp. 6-8
    • Hormigo, A.1    Gutin, P.H.2    Rafii, S.3
  • 36
    • 34248665600 scopus 로고    scopus 로고
    • Dynamic contrast enhanced magnetic resonance imaging in oncology: Theory, data acquisition, analysis, and examples
    • DOI 10.2174/157340507780619179
    • T.E. Yankeelov, and J.C. Gore Dynamic contrast enhanced magnetic resonance imaging in oncology: theory, data acquisition, analysis, and examples Curr Med Imaging Rev 3 2009 91 107 (Pubitemid 46773870)
    • (2007) Current Medical Imaging Reviews , vol.3 , Issue.2 , pp. 91-107
    • Yankeelov, T.E.1    Gore, J.C.2
  • 37
    • 34250778970 scopus 로고    scopus 로고
    • Imaging tumor vascular heterogeneity and angiogenesis using dynamic contrast-enhanced magnetic resonance imaging
    • DOI 10.1158/1078-0432.CCR-07-0238
    • A. Jackson, J.P.B. O'Connor, G.J.M. Parker, and G.C. Jayson Imaging tumor vascular heterogeneity and angiogenesis using dynamic contrast-enhanced magnetic resonance imaging Clin Cancer Res 13 2007 3449 3459 (Pubitemid 46955104)
    • (2007) Clinical Cancer Research , vol.13 , Issue.12 , pp. 3449-3459
    • Jackson, A.1    O'Connor, J.P.B.2    Parker, G.J.M.3    Jayson, G.C.4
  • 38
    • 73049092595 scopus 로고    scopus 로고
    • Geographic difference in survival outcome for advanced hepatocellular carcinoma: Implications on future clinical trial design
    • C. Hsu, Y.C. Shen, C.C. Cheng, F.C. Hu, and A.L. Cheng Geographic difference in survival outcome for advanced hepatocellular carcinoma: implications on future clinical trial design Contemp Clin Trials 31 2010 55 61
    • (2010) Contemp Clin Trials , vol.31 , pp. 55-61
    • Hsu, C.1    Shen, Y.C.2    Cheng, C.C.3    Hu, F.C.4    Cheng, A.L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.