Click to a focused library of benzyl 6-triazolo(hydroxy)benzoic glucosides: Novel construction of PTP1B inhibitors on a sugar scaffold

European Journal of Medicinal Chemistry

Volumn 46, Issue 9, 2011, Pages 4212-4218

  Li, Cui ^a   He, Xiao Peng ^a,c   Zhang, Yin Jie ^a   Li, Zhen ^a   Gao, Li Xin ^b   Shi, Xiao Xin ^a   Xie, Juan ^c   Li, Jia ^b   Chen, Guo Rong ^a   Tang, Yun ^a  

^a EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

^c Ecole Normale Superieure de Cachan   (France)

Author keywords

(Hydroxy)benzoate; Click chemistry; Molecular docking; PTP1B inhibitor; Sugar scaffold

Indexed keywords

ALKYNE; AZIDE; BENZYL 6 TRIAZOLO(HYDROXY)BENZOIC GLUCOSIDE DERIVATIVE; COPPER; GLYCOCONJUGATE; LEUKOCYTE ANTIGEN; MOLECULAR SCAFFOLD; PROTEIN SH2; PROTEIN TYROSINE PHOSPHATASE; PROTEIN TYROSINE PHOSPHATASE 1B INHIBITOR; SUGAR; UNCLASSIFIED DRUG;

ARTICLE; CLICK CHEMISTRY; DRUG SELECTIVITY; DRUG SYNTHESIS; MOLECULAR DOCKING; T LYMPHOCYTE;

BENZOIC ACID; CARBOHYDRATES; ENZYME INHIBITORS; GLUCOSIDES; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 80052931758     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2011.06.025     Document Type: Article

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