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Volumn 40, Issue , 2011, Pages 2-9

History of drug discovery: Early evaluation studies and lessons learnt from them

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EID: 80052917910     PISSN: 14222140     EISSN: 16623932     Source Type: Book Series    
DOI: 10.1159/000324894     Document Type: Article
Times cited : (8)

References (42)
  • 1
    • 0000136419 scopus 로고
    • Die Aetiologie der Tuberkulose
    • Koch R: Die Aetiologie der Tuberkulose. Berl Klin Wochenschr 1882;19:221-230.
    • (1882) Berl Klin Wochenschr , vol.19 , pp. 221-230
    • Koch, R.1
  • 2
    • 0344343286 scopus 로고
    • The specific action of a bacterial enzyme on pneumococci of type III
    • Avery OT, Dubos RJ: The specific action of a bacterial enzyme on pneumococci of type III. Science 1930;72B:151-152.
    • (1930) Science , vol.72 B , pp. 151-152
    • Avery, O.T.1    Dubos, R.J.2
  • 3
    • 0242628703 scopus 로고
    • Ein beitrag zur chemotherapie der bakteriellen infektionen
    • Domagk G: Ein Beitrag zur Chemotherapie der bakteriellen Infektionen. Dtsch Med Wochenschr 1935;61:250-253.
    • (1935) Dtsch Med Wochenschr , vol.61 , pp. 250-253
    • Domagk, G.1
  • 4
    • 34250955600 scopus 로고
    • Über eine neue gegen Tuberkelbazillen in vitro wirksame Verbindungsklasse
    • Domagk G, Behnisch R, Mietzsch F, Schmidt H: Über eine neue, gegen Tuberkelbazillen in vitro wirksame Verbindungsklasse. Naturwissenschaften 1946;33:1-4.
    • (1946) Naturwissenschaften , vol.33 , pp. 1-4
    • Domagk, G.1    Behnisch, R.2    Mietzsch, F.3    Schmidt, H.4
  • 5
    • 0005172566 scopus 로고
    • Bactericidal effect of an extract of a soil bacillus on Gram positive cocci
    • Dubos RJ: Bactericidal effect of an extract of a soil bacillus on Gram positive cocci. Proc Soc Exp Biol Med 1939;40:311-312.
    • (1939) Proc Soc Exp Biol Med , vol.40 , pp. 311-312
    • Dubos, R.J.1
  • 6
    • 84964134387 scopus 로고
    • Streptomycin, a substance exhibiting antibiotic activity against Gram-positive and Gram-negative bacteria
    • Schatz A, Bugie E, Waksman S: Streptomycin, a substance exhibiting antibiotic activity against Gram-positive and Gram-negative bacteria. Proc Soc Exp Biol Med 1944;55:66-69.
    • (1944) Proc Soc Exp Biol Med , vol.55 , pp. 66-69
    • Schatz, A.1    Bugie, E.2    Waksman, S.3
  • 7
    • 0013029761 scopus 로고
    • Effects of streptomycin on experimental tuberculosis in guinea pigs
    • Feldman WH, Hinshaw HC: Effects of streptomycin on experimental tuberculosis in guinea pigs. Proc Staff Meet Mayo Clin 1944;19:593-599.
    • (1944) Proc Staff Meet Mayo Clin , vol.19 , pp. 593-599
    • Feldman, W.H.1    Hinshaw, H.C.2
  • 9
    • 2542481693 scopus 로고
    • Treatment of tuberculosis with streptomycin: A summary of observations on one hundred cases
    • Hinshaw HC, Feldman WH, Pfuetze KH: Treatment of tuberculosis with streptomycin: A summary of observations on one hundred cases, J Am Med Assoc 1946;132:778-782.
    • (1946) J Am Med Assoc , vol.132 , pp. 778-782
    • Hinshaw, H.C.1    Feldman, W.H.2    Pfuetze, K.H.3
  • 10
    • 77951529251 scopus 로고
    • Medical research council investigation: Streptomycin treatment of pulmonary tuberculosis
    • Medical Research Council investigation: Streptomycin treatment of pulmonary tuberculosis. Br Med J 1948;ii:769-782.
    • (1948) Br Med J , vol.2 , pp. 769-782
  • 11
    • 0008429321 scopus 로고
    • Evaluation of chemotherapeutic agents in clinical tuberculosis: A suggested procedure
    • Hinshaw HC, Feldman WH: Evaluation of chemotherapeutic agents in clinical tuberculosis: A suggested procedure. Am Rev Tuberc 1944;50:202-213.
    • (1944) Am Rev Tuberc , vol.50 , pp. 202-213
    • Hinshaw, H.C.1    Feldman, W.H.2
  • 12
    • 0002162781 scopus 로고
    • Para-aminosalicylic acid in the treatment of tuberculosis
    • Lehmann J: Para-aminosalicylic acid in the treatment of tuberculosis. Lancet 1946;247:15-16.
    • (1946) Lancet , vol.247 , pp. 15-16
    • Lehmann, J.1
  • 13
    • 37049218533 scopus 로고
    • The effect of salicylate on the oxygen uptake of the tubercle bacillus
    • Bernheim F: The effect of salicylate on the oxygen uptake of the tubercle bacillus. Science 1940;92:204.
    • (1940) Science , vol.92 , pp. 204
    • Bernheim, F.1
  • 14
    • 0001472399 scopus 로고
    • Medical research council investigation: Treatment of pulmonary tuberculosis with streptomycin and para-amino-salicylic acid
    • Medical Research Council Investigation: Treatment of pulmonary tuberculosis with streptomycin and para-amino-salicylic acid. Br Med J 1950;ii:1073-1085.
    • (1950) Br Med J , vol.2 , pp. 1073-1085
  • 17
    • 0013380386 scopus 로고
    • Note sur l'action de très fortes doses d'amide nicotinique dans les lésions bacillaires
    • Huant E: Note sur l'action de très fortes doses d'amide nicotinique dans les lésions bacillaires. Gaz Hôp 1945;16:259-260.
    • (1945) Gaz Hôp , vol.16 , pp. 259-260
    • Huant, E.1
  • 18
    • 0001019102 scopus 로고
    • Action de l'amide nicotinique sur les bacilles du genre
    • Chorine V: Action de l'amide nicotinique sur les bacilles du genre Mycobacterium. C R Acad Sci 1945:220:150-151.
    • (1945) Mycobacterium. C R Acad Sci , vol.220 , pp. 150-151
    • Chorine, V.1
  • 19
    • 80052954436 scopus 로고
    • Editorial: New drugs for tuberculosis
    • Editorial: New drugs for tuberculosis. N Engl J Med 1952;246:797-799.
    • (1952) N Engl J Med , vol.246 , pp. 797-799
  • 20
    • 33746499392 scopus 로고
    • Ein weiterer Beitrag zur experimentellen Chemotherapie der Tuberkulose (Neoteben)
    • Domagk G, Offe HA, Siefken W: Ein weiterer Beitrag zur experimentellen Chemotherapie der Tuberkulose (Neoteben). Dtsch Med Wochenschr 1952;77:573-578.
    • (1952) Dtsch Med Wochenschr , vol.77 , pp. 573-578
    • Domagk, G.1    Offe, H.A.2    Siefken, W.3
  • 21
    • 0000650435 scopus 로고
    • Pharmacologic and toxicologic observations on hydrazine derivatives of isonicotinic acid (Rimifon, Marsilid)
    • Benson WM, Stefko PL, Roe MD: Pharmacologic and toxicologic observations on hydrazine derivatives of isonicotinic acid (Rimifon, Marsilid). Am Rev Tuberc 1952;65:376-391.
    • (1952) Am Rev Tuberc , vol.65 , pp. 376-391
    • Benson, W.M.1    Stefko, P.L.2    Roe, M.D.3
  • 22
    • 0001352336 scopus 로고
    • The chemical approach to the control of tuberculosis
    • Fox HH: The chemical approach to the control of tuberculosis. Science 1952;116:129-134.
    • (1952) Science , vol.116 , pp. 129-134
    • Fox, H.H.1
  • 23
    • 84958294760 scopus 로고
    • Chemotherapy of experimental tuberculosis. V. Isonicotinic acid hydrazide (Nydrazid) and related compounds
    • Bernstein J, Lott WA, Steinberg BA, Yale HL: Chemotherapy of experimental tuberculosis. V. Isonicotinic acid hydrazide (Nydrazid) and related compounds. Am Rev Tuberc 1952;65:357-364.
    • (1952) Am Rev Tuberc , vol.65 , pp. 357-364
    • Bernstein, J.1    Lott, W.A.2    Steinberg, B.A.3    Yale, H.L.4
  • 24
    • 0001210540 scopus 로고
    • Medical research council: The treatment of pulmonary tuberculosis with isoniazid
    • Medical Research Council: The treatment of pulmonary tuberculosis with isoniazid. Br Med J 1952;ii:735-746.
    • (1952) Br Med J , vol.2 , pp. 735-746
  • 25
    • 84965316031 scopus 로고
    • Medical research council: Isoniazid in the treatment of pulmonary tuberculosis
    • Medical Research Council: Isoniazid in the treatment of pulmonary tuberculosis. Br Med J 1953;i:521-536.
    • (1953) Br Med J , vol.1 , pp. 521-536
  • 26
    • 84965314501 scopus 로고
    • Medical research council: Isoniazid in combination with streptomycin or with PAS in the treatment of pulmonary tuberculosis
    • Medical Research Council: Isoniazid in combination with streptomycin or with PAS in the treatment of pulmonary tuberculosis. Br Med J 1953;ii:1005-1014.
    • (1953) Br Med J , vol.2 , pp. 1005-1014
  • 27
    • 84970843943 scopus 로고
    • Medical research council: Various combinations of isoniazid with streptomycin or with PAS in the treatment of pulmonary tuberculosis
    • Medical Research Council: Various combinations of isoniazid with streptomycin or with PAS in the treatment of pulmonary tuberculosis. Br Med J 1955;i:435-445.
    • (1955) Br Med J , vol.1 , pp. 435-445
  • 28
    • 85004630519 scopus 로고
    • Medical research council-Tuberculosis chemotherapy trials committee: Long-term chemotherapy in the treatment of chronic pulmonary tuberculosis with cavitation
    • Medical Research Council-Tuberculosis Chemotherapy Trials Committee: Long-term chemotherapy in the treatment of chronic pulmonary tuberculosis with cavitation. Tubercle 1962;43:201-267.
    • (1962) Tubercle , vol.43 , pp. 201-267
  • 29
    • 0003190853 scopus 로고
    • International union against tuberculosis: An international investigation of the efficacy of chemotherapy
    • International Union against Tuberculosis: An international investigation of the efficacy of chemotherapy. Bull Int Union Tuberc 1964;34:79-191.
    • (1964) Bull Int Union Tuberc , vol.34 , pp. 79-191
  • 30
    • 0012509398 scopus 로고
    • Ambulatory chemotherapy in a developing country: Clinical and epidemiological studies
    • Fox W: Ambulatory chemotherapy in a developing country: Clinical and epidemiological studies. Adv Tuberc Res 1963;12:28-149.
    • (1963) Adv Tuberc Res , vol.12 , pp. 28-149
    • Fox, W.1
  • 31
    • 80052941894 scopus 로고
    • Methods of chemotherapy in developing countries
    • Fox W: Methods of chemotherapy in developing countries. Bull Int Union Tuberc 1966;337:249-260.
    • (1966) Bull Int Union Tuberc , vol.337 , pp. 249-260
    • Fox, W.1
  • 33
    • 0001331161 scopus 로고
    • History of development of rifampin
    • Sensi P: History of development of rifampin. Rev Infect Dis 1983;5:S402-S406.
    • (1983) Rev Infect Dis , vol.5
    • Sensi, P.1
  • 34
    • 0014128753 scopus 로고
    • Activité antituberculeuse expérimentale de la rifampicine dérivée de la rifamycine S.V
    • Grumbach F, Rist N: Activité antituberculeuse expérimentale de la rifampicine, dérivée de la rifamycine SV. Rev Tuberc Pneum 1967;31:749-762.
    • (1967) Rev Tuberc Pneum , vol.31 , pp. 749-762
    • Grumbach, F.1    Rist, N.2
  • 35
    • 77950341662 scopus 로고
    • Short-course chemotherapy in pulmonary tuberculosis: A controlled trial
    • British Thoracic and Tuberculosis Association.
    • British Thoracic and Tuberculosis Association: Short-course chemotherapy in pulmonary tuberculosis: A controlled trial. Lancet 1976;ii:1102-1104.
    • (1976) Lancet , vol.2 , pp. 1102-1104
  • 36
    • 0343494455 scopus 로고
    • Effect of nicotinamide acid amide on experimental tuberculosis of white mice
    • McKensie D, Malone L, Kushner S, Oleson JJ, Subbarow Y: Effect of nicotinamide acid amide on experimental tuberculosis of white mice. J Lab Clin Med 1948;33:1249-1253.
    • (1948) J Lab Clin Med , vol.33 , pp. 1249-1253
    • McKensie, D.1    Malone, L.2    Kushner, S.3    Oleson, J.J.4    Subbarow, Y.5
  • 39
    • 76949116151 scopus 로고
    • Pyrazinamide (Aldinamide) in the treatment of pulmonary tuberculosis
    • Yeager RL, Munroe WGC, Dessau FI: Pyrazinamide (Aldinamide) in the treatment of pulmonary tuberculosis. Am Rev Tuberc 1952;65:523-534.
    • (1952) Am Rev Tuberc , vol.65 , pp. 523-534
    • Yeager, R.L.1    Munroe, W.G.C.2    Dessau, F.I.3
  • 40
    • 84890265975 scopus 로고
    • East african/british medical research councils: Controlled clinical trial of short-course (6-month) regimens of chemotherapy for treatment of pulmonary tuberculosis
    • East African/British Medical Research Councils: Controlled clinical trial of short-course (6-month) regimens of chemotherapy for treatment of pulmonary tuberculosis. Lancet 1972;i:1079-1085.
    • (1972) Lancet , vol.1 , pp. 1079-1085
  • 41
    • 0016839067 scopus 로고
    • Hong kong tuberculosis treatment services/ British medical research council: Controlled trial of 6-and 9-month regimens of daily and intermittent streptomycin plus isoniazid plus pyrazinamide for pulmonary tuberculosis in Hong Kong
    • Hong Kong Tuberculosis Treatment Services/ British Medical Research Council: Controlled trial of 6-and 9-month regimens of daily and intermittent streptomycin plus isoniazid plus pyrazinamide for pulmonary tuberculosis in Hong Kong. Tubercle 1975;56:81-96.
    • (1975) Tubercle , vol.56 , pp. 81-96
  • 42
    • 0021149963 scopus 로고
    • British thoracic society: A controlled trial of 6 months' chemotherapy in pulmonary tuberculosis. Final report: Results during the 36 months after the end of chemotherapy and beyond
    • British Thoracic Society: A controlled trial of 6 months' chemotherapy in pulmonary tuberculosis. Final report: Results during the 36 months after the end of chemotherapy and beyond. Br J Dis Chest 1984;78:330-336.
    • (1984) Br J Dis Chest , vol.78 , pp. 330-336


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