Administrative practices of health professionals and use of artesunate-amodiaquine by community members for treating uncomplicated malaria in southern Ghana: Implications for artemisinin-based combination therapy deployment

Tropical Medicine and International Health

Volumn 16, Issue 10, 2011, Pages 1215-1224

  Kwansa Bentum, Bethel ^a,b   Ayi, Irene ^b   Suzuki, Takashi ^a,b   Otchere, Joseph ^b   Kumagai, Takashi ^a   Anyan, William K ^b   Asahi, Hiroko ^c   Akao, Nobuaki ^a   Wilson, Michael D ^b   Boakye, Daniel A ^b   Ohta, Nobuo ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b University of Ghana   (Ghana)

^c NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

Author keywords

Artesunate amodiaquine; Community members; Compliance; Ghana; Health professionals; Malaria

Indexed keywords

AMODIAQUINE PLUS ARTESUNATE; ANTIMALARIAL AGENT; ARTEMETHER PLUS BENFLUMETOL; ARTESUNATE; CHLOROQUINE; DIHYDROARTEMISININ; PYRIMETHAMINE PLUS SULFADOXINE; QUININE;

ANTIMALARIAL AGENT; COMMUNITY HEALTH WORKER; DISEASE TREATMENT; DRUG; HEALTH SERVICES; HOSPITAL SECTOR; MALARIA; MEDICINE; PUBLIC HEALTH; QUESTIONNAIRE SURVEY;

ADOLESCENT; ADULT; ANTIMALARIAL ACTIVITY; ARTICLE; CHILD; CROSS-SECTIONAL STUDY; DRUG USE; FEMALE; GHANA; HEALTH PRACTITIONER; HOSPITAL; HUMAN; KNOWLEDGE; MALARIA; MALE; MEDICAL PRACTICE; MONOTHERAPY; PRESCHOOL CHILD; PRESCRIPTION; QUESTIONNAIRE; RURAL AREA; SCHOOL CHILD; URBAN AREA;

ADOLESCENT; ADULT; AGED; AMODIAQUINE; ANTIMALARIALS; ARTEMISININS; CHILD; CHILD, PRESCHOOL; COMMUNITY-BASED PARTICIPATORY RESEARCH; DRUG COMBINATIONS; DRUG RESISTANCE, MICROBIAL; DRUG THERAPY, COMBINATION; DRUG UTILIZATION; FEMALE; GHANA; HEALTH CARE SURVEYS; HUMANS; INFANT; MALE; MIDDLE AGED; NURSES; PHARMACISTS; PHARMACISTS' AIDES; PHYSICIAN'S PRACTICE PATTERNS; PHYSICIANS; QUESTIONNAIRES; RURAL POPULATION; URBAN POPULATION;

GHANA;

ARTESUNATE;

EID: 80052911732     PISSN: 13602276     EISSN: 13653156     Source Type: Journal    
DOI: 10.1111/j.1365-3156.2011.02833.x     Document Type: Article

References (32)

1. Abuaku BK, Koram KA & Binka FN (2005) Antimalarial prescribing practices: a challenge to malaria control in Ghana. Medical Principles and Practice 14, 332-337.
2. Adjei GO, Darkwah AK, Goka BQ et al. (2008) Parents' perceptions, attitudes and acceptability of treatment of childhood malaria with artemisinin combination therapies in Ghana. Ghana Medical Journal 42, 99-106.
3. Adjuik M, Agnamey P, Babiker A et al. (2002) Amodiaquine-artesunate versus amodiaquine for uncomplicated Plasmodium falciparum malaria in African children: a randomised, multicentre trial. The Lancet 359, 1365-1372.
4. Agyepong IA (1992) Malaria: ethnomedical perceptions and practice in an Adangbe farming community and implications for control. Social Science and Medicine 35, 131-137.
5. Ahorlu CK, Dunyo SK, Afari EA, Koram KA & Nkrumah FK (1997) Malaria-related beliefs and behaviour in southern Ghana: implications for treatment, prevention and control. Tropical Medicine and International Health 2, 488-499.
6. Ahorlu CK, Koram KA, Ahorlu C, de Savigny D & Weiss MG (2006) Socio-cultural determinants of treatment delay for childhood malaria in southern Ghana. Tropical Medicine and International Health 11, 1022-1031.
7. Akompong TS, Eksi S, Williamson K & Haldar K (2000) Gametocytocidal activity and synergistic interactions of riboflavin with standard anti-malarial drugs against growth of Plasmodium falciparum in vitro. Antimicrobial Agents and Chemotherapy 44, 3107-3111.
8. Appawu MA, Baffoe-Wilmot A, Afari EA et al. (2001) Malaria vector studies in two ecological zones in southern Ghana. African Entomology 9, 59-65.
9. Asante KP, Owusu R, Dosoo D et al. (2009) Adherence to artesunate-amodiaquine therapy for uncomplicated malaria in Rural Ghana: a randomised trial of supervised versus unsupervised drug administration. Journal of Tropical Medicine 2009, 1-7.
10. Asante KP, Abokyi L, Zandoh C et al. (2010) Community perceptions of malaria and malaria treatment behaviour in a rural district of Ghana: implications for artemisinin combination therapy. BMC Public Health 10, 409.
11. Bosman A & Mendis KN (2007) A major transition in malaria treatment: the adoption and deployment of artemisinin-based combination therapies. American Journal of Tropical Medicine and Hygiene 77(Suppl 6), 193-197.
12. Dellicour S, Hall S, Chandramohan D & Greenwood B (2007) The safety of artemisinins during pregnancy: a pressing question. Malaria Journal 6, 15.
13. Ghana Health Service (2004) Guidelines for Case Management of Malaria in Ghana.
14. Ghana Health Service (2009) Guidelines for Case Management of Malaria in Ghana.
15. Ghana News Agency (2010) Seventy Medicine Counter Assistants graduate.
16. Hatton CS, Peto TE, Bunch C et al. (1986) Frequency of severe neutropenia associated with amodiaquine prophylaxis against malaria. The Lancet 1, 411-414.
17. McGready R, Cho T, Keo NK et al. (2001) Artemisinin antimalarials in pregnancy: a prospective treatment study of 539 episodes of multidrug-resistant Plasmodium falciparum. Clinical Infectious Diseases 33, 2009-2016.
18. McGready R, Tan SO, Ashley EA et al. (2008) A randomised controlled trial of artemether-lumefantrine versus artesunate for non-complicated Plasmodium falciparum treatment in pregnancy. PLoS Medicine 5, 12.
19. Neftel KA, Woodtly W, Schmid M, Frick PG & Fehr J (1986) Amodiaquine induced agranulocytosis and liver damage. British Medical Journal (Clinical research ed.) 292, 721-723.
20. Nichter M (2008) Global Health: Why Cultural Perceptions, Social Representations and Biopolitics Matter. University of Arizona Press, Tucson.
21. Okoye PN, Wilson MD, Boakye DA & Brown CA (2005) Impact of the Okyereko irrigation project in Ghana on the risk of human malaria infection by Anopheles species (Diptera: Culicidae). African Entomology 13, 249-253.
22. Olliaro P, Nevill C, LeBras J et al. (1996) Systematic review of amodiaquine treatment in uncomplicated malaria. The Lancet 348, 1196-1201.
23. Orrell C, Taylor WR & Olliaro P (2001) Acute asymptomatic hepatitis in a healthy normal volunteer exposed to 2 oral doses of amodiaquine and artesunate. Transactions of the Royal Society of Tropical Medicine and Hygiene 95, 517-518.
24. Owusu G (2005) Small Towns in Ghana: justifications for their promotion under Ghana's Decentralisation Programme. African Studies Quarterly 8, 48-69.
25. Robert A, Benoit-Vical F, Dechy-Cabaret O & Meunier B (2001) From classical antimalarial drugs to new compounds based on the mechanism of action of artemisinin. Pure and Applied Chemistry 73, 1173-1188.
26. Ubalee R, Songthammawat D, Na-Bangchang K, Tan-ariya P & Karbwang J (1999) Ex vivo blood schizonticidal activities of artemisinin derivatives against Plasmodium falciparum. The Southeast Asian Journal of Tropical Medicine and Public Health 30, 225-231.
27. van der Geest S, Hardon A & Whyte SR (1990) Planning for essential drugs: are we missing the cultural dimension? Health Policy and Planning 5, 182-185.
28. White NJ (1998) Preventing antimalarial drug resistance through combinations. Drug Resistance Updates 1, 3-9.
29. WHO (2006) The new anti-malaria drug policy for Ghana.
30. WHO Facts on ACTs (Artemisinin-based combination therapies).
31. WHO/AFRO (2003) Framework for developing, implementing and updating National Antimalaria treatment Policy: a guide for country malaria control programmes. AFR/MAL/03.02.
32. Yeboah EK (2005) Stop Sale: Ministry Orders Withdrawal of Two Brands of New Malarial Drugs. Daily Graphic, Ghana.