Human NK cells differ more in their KIR2DL1-dependent thresholds for HLA-Cw6-mediated inhibition than in their maximal killing capacity

PLoS ONE

Volumn 6, Issue 9, 2011, Pages

  Almeida, Catarina R ^a,c   Ashkenazi, Amit ^b   Shahaf, Gitit ^b   Kaplan, Deborah ^b   Davis, Daniel M ^a   Mehr, Ramit ^b  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b BAR ILAN UNIVERSITY   (Israel)

^c INEB INSTITUTO DE ENGENHARIA BIOMÉDICA   (Portugal)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; HLA ANTIGEN CLASS 1; HLA CW6 ANTIGEN; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR 2DL1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; UNCLASSIFIED DRUG; HLA C ANTIGEN; HLA C*06 ANTIGEN; HLA-C*06 ANTIGEN; KIR2DL1 PROTEIN, HUMAN;

ARTICLE; CELL KILLING; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOLYSIS; DEGRANULATION; HUMAN; HUMAN CELL; LYMPHOCYTE ACTIVATION; LYMPHOCYTE CLONE; MATHEMATICAL MODEL; NATURAL KILLER CELL; PROTEIN EXPRESSION; TARGET CELL; APOPTOSIS; CELL CLONE; CELL CULTURE; CYTOTOXICITY; FLOW CYTOMETRY; IMMUNOLOGY; METABOLISM; PATHOLOGY; THEORETICAL MODEL;

APOPTOSIS; CELLS, CULTURED; CLONE CELLS; CYTOTOXICITY, IMMUNOLOGIC; FLOW CYTOMETRY; HISTOCOMPATIBILITY ANTIGENS CLASS I; HLA-C ANTIGENS; HUMANS; KILLER CELLS, NATURAL; MODELS, THEORETICAL; RECEPTORS, KIR2DL1;

EID: 80052910202     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0024927     Document Type: Article

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