Transcranial Doppler Studies on Cerebral Autoregulation Suggest Prolonged Cerebral Vasoconstriction in a Subgroup of Patients with Orthostatic Intolerance

Ultrasound in Medicine and Biology

Volumn 37, Issue 10, 2011, Pages 1554-1560

  Lin, Ya Ju ^a,b   Po, Helen L ^b   Hsu, Hung Yi ^c,d   Chung, Chih Ping ^a,e   Sheng, Wen Yung ^e   Hu, Han Hwa ^a,e  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

^b MACKAY MEMORIAL HOSPITAL   (Taiwan)

^c Department of Neurology   (Taiwan)

^d CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^e TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

Author keywords

Cerebral autoregulation; Orthostatic intolerance; Tilt table; Transcranial Doppler ultrasonography; Valsalva maneuver

Indexed keywords

CEREBRAL AUTOREGULATION; ORTHOSTATIC INTOLERANCE; TILT TABLE; TRANSCRANIAL DOPPLER ULTRASONOGRAPHY; VALSALVA MANEUVER;

BLOOD PRESSURE;

ULTRASONOGRAPHY;

ADULT; ARTICLE; AUTOREGULATION; BLOOD PRESSURE MONITORING; BRAIN CIRCULATION; BRAIN VASCULAR RESISTANCE; CLINICAL ARTICLE; CLINICAL ASSESSMENT; CONTROLLED STUDY; DIZZINESS; DOPPLER ECHOGRAPHY; ELECTROCARDIOGRAPHY MONITORING; FEMALE; FLOW RATE; HEAD TILTING; HEMODYNAMICS; HUMAN; MALE; MIDDLE CEREBRAL ARTERY; NEUROIMAGING; ORTHOSTATIC INTOLERANCE; PRIORITY JOURNAL; PULSATILE FLOW; SYNCOPE; VALSALVA MANEUVER; VASOCONSTRICTION;

ADULT; AUTONOMIC NERVOUS SYSTEM; BLOOD FLOW VELOCITY; CASE-CONTROL STUDIES; FEMALE; HEMODYNAMICS; HUMANS; MALE; MIDDLE CEREBRAL ARTERY; POSTURAL ORTHOSTATIC TACHYCARDIA SYNDROME; STATISTICS, NONPARAMETRIC; TILT-TABLE TEST; ULTRASONOGRAPHY, DOPPLER, TRANSCRANIAL; VALSALVA MANEUVER; VASOCONSTRICTION;

EID: 80052891181     PISSN: 03015629     EISSN: 1879291X     Source Type: Journal    
DOI: 10.1016/j.ultrasmedbio.2011.06.008     Document Type: Article

References (36)

1. Agarwal A.K., Garg R., Ritch A., Sarkar P. Postural orthostatic tachycardia syndrome. Postgrad Med J 2007, 83:478-480.
2. Bisharat N., Paz E., Klimov A., Friedberg N., Elias M. Cerebral syncope in a patient with spinal cord injury. Pacing Clin Electrophysiol 2002, 25:372-373.
3. Bragoni M., Feldmann E. Transcranial doppler indices of intracranial hemodynamics. Neurosonology 1995, 129-139. Mosby-Year Book, St. Louis. C.H. Tegeler, V.L. Babikian, C.R. Gomez (Eds.).
4. Carew S., Connor M.O., Cooke J., Conway R., Sheehy C., Costelloe A., Lyons D. A review of postural orthostatic tachycardia syndrome. Europace 2009, 11:18-25.
5. Cencetti S., Bandinelli G., Lagi A. Effect of pco2 changes induced by head-upright tilt on transcranial Doppler recordings. Stroke 1997, 28:1195-1197.
6. Chao A.C., Hu H.H., Liao K.K., Chern C.M. Dynamic cerebrovascular regulation in patients with autonomic dysfunction: A transcranial doppler study. J Chin Med Assoc 2003, 66:339-345.
7. Czosnyka M., Richards H.K., Whitehouse H.E., Pickard J.D. Relationship between transcranial Doppler-determined pulsatility index and cerebrovascular resistance: An experimental study. J Neurosurg 1996, 84:79-84.
8. Daffertshofer M., Hennerici M. Cerebrovascular regulation and vasoneuronal coupling. J Clin Ultrasound 1995, 23:125-138.
9. Freeman R., Kaufmann H. Disorders of orthostatic tolerance-orthostatic hypotension, postural tachycardia syndrome, and syncope. CONTINUUM: Lifelong Learning in Neurology 2007, 13:50-88.
10. Gibbs D.M. Hyperventilation-induced cerebral ischemia in panic disorder and effect of nimodipine. Am J Psychiatr 1992, 149:1589-1591.
11. Gosling R.G., King D.H. Arterial assessment by Doppler-shift ultrasound. Proc R Soc Med 1974, 67:447-449.
12. Greenfield J.C., Rembert J.C., Tindall G.T. Transient changes in cerebral vascular resistance during the valsalva maneuver in man. Stroke 1984, 15:76-79.
13. Grubb B.P. Cerebral syncope: New insights into an emerging entity. J Pediatr 2000, 136:431-432.
14. Grubb B.P., Gerard G., Roush K., Temesy-Armos P., Montford P., Elliott L., Hahn H., Brewster P. Cerebral vasoconstriction during head-upright tilt-induced vasovagal syncope. A paradoxic and unexpected response. Circulation 1991, 84:1157-1164.
15. Grubb B.P., Samoil D., Kosinski D., Wolfe D., Brewster P., Elliott L., Hahn H. Cerebral syncope: Loss of consciousness associated with cerebral vasoconstriction in the absence of systemic hypotension. Pacing Clin Electrophysiol 1998, 21:652-658.
16. Hermosillo A.G., Jordan J.L., Vallejo M., Kostine A., Marquez M.F., Cardenas M. Cerebrovascular blood flow during the near syncopal phase of head-up tilt test: A comparative study in different types of neurally mediated syncope. Europace 2006, 8:199-203.
17. Hsu H.Y., Chern C.M., Kuo J.S., Kuo T.B., Chen Y.T., Hu H.H. Correlations among critical closing pressure, pulsatility index and cerebrovascular resistance. Ultrasound Med Biol 2004, 30:1329-1335.
18. Jacob G., Atkinson D., Jordan J., Shannon J.R., Furlan R., Black B.K., Robertson D. Effects of standing on cerebrovascular resistance in patients with idiopathic orthostatic intolerance. Am J Med 1999, 106:59-64.
19. Jacob G., Costa F., Shannon J.R., Robertson R.M., Wathen M., Stein M., Biaggioni I., Ertl A., Black B., Robertson D. The neuropathic postural tachycardia syndrome. N Engl J Med 2000, 343:1008-1014.
20. Jauregui-Renaud K., Hermosillo J.A., Jardon J.L., Marquez M.F., Kostine A., Silva M.A., Cardenas M. Cerebral blood flow during supine rest and the first minute of head-up tilt in patients with orthostatic intolerance. Europace 2005, 7:460-464.
21. Jordan J., Shannon J.R., Diedrich A., Black B.K., Robertson D. Increased sympathetic activation in idiopathic orthostatic intolerance: Role of systemic adrenoreceptor sensitivity. Hypertension 2002, 39:173-178.
22. Lagi A., Bacalli S., Cencetti S., Paggetti C., Colzi L. Cerebral autoregulation in orthostatic hypotension. A transcranial doppler study. Stroke 1994, 25:1771-1775.
23. Low P.A., Novak V., Spies J.M., Novak P., Petty G.W. Cerebrovascular regulation in the postural orthostatic tachycardia syndrome (pots). Am J Med Sci 1999, 317:124-133.
24. Low P.A., Opfer-Gehrking T.L., Textor S.C., Benarroch E.E., Shen W.K., Schondorf R., Suarez G.A., Rummans T.A. Postural tachycardia syndrome (pots). Neurology 1995, 45:S19-S25.
25. Low P.A., Sandroni P., Joyner M., Shen W.K. Postural tachycardia syndrome (pots). J Cardiovasc Electrophysiol 2009, 20:352-358.
26. Njemanze P.C. Cerebral circulation dysfunction and hemodynamic abnormalities in syncope during upright tilt test. Can J Cardiol 1993, 9:238-242.
27. Norcliffe-Kaufmann L.J., Kaufmann H., Hainsworth R. Enhanced vascular responses to hypocapnia in neurally mediated syncope. Ann Neurol 2008, 63:288-294.
28. Novak V., Novak P., Spies J.M., Low P.A. Autoregulation of cerebral blood flow in orthostatic hypotension. Stroke 1998, 29:104-111.
29. Novak V., Spies J.M., Novak P., McPhee B.R., Rummans T.A., Low P.A. Hypocapnia and cerebral hypoperfusion in orthostatic intolerance. Stroke 1998, 29:1876-1881.
30. Schondorf R., Benoit J., Stein R. Cerebral autoregulation in orthostatic intolerance. Ann N Y Acad Sci 2001, 940:514-526.
31. Schondorf R., Benoit J., Wein T. Cerebrovascular and cardiovascular measurements during neurally mediated syncope induced by head-up tilt. Stroke 1997, 28:1564-1568.
32. Schondorf R., Low P.A. Idiopathic postural orthostatic tachycardia syndrome: An attenuated form of acute pandysautonomia?. Neurology 1993, 43:132-137.
33. Streeten D.H. Pathogenesis of hyperadrenergic orthostatic hypotension. Evidence of disordered venous innervation exclusively in the lower limbs. J Clin Invest 1990, 86:1582-1588.
34. Tiecks F.P., Douville C., Byrd S., Lam A.M., Newell D.W. Evaluation of impaired cerebral autoregulation by the valsalva maneuver. Stroke 1996, 27:1177-1182.
35. Wang Y.J., Chao A.C., Chung C.P., Huang Y.J., Hu H.H. Different cerebral hemodynamic responses between sexes and various vessels in orthostatic stress tests. J Ultrasound Med 2010, 29:1299-1304.
36. Wu I.H., Sheng W.Y., Hu H.H., Chung C.P. Jugular venous reflux could inflence cerebral blood flow: A Transcranial Doppler study. Acta Neurolgica Taiwanica 2011, (in press).