Role of early intravenous to oral antibiotic switch therapy in the management of prosthetic hip infection treated with one- or two-stage replacement

Journal of Antimicrobial Chemotherapy

Volumn 66, Issue 10, 2011, Pages 2405-2408

  Darley, E S R ^a   Bannister, G C ^a   Blom, A W ^a   Macgowan, A P ^a   Jacobson, S K ^a   Alfouzan, W ^a  

^a SOUTHMEAD HOSPITAL   (United Kingdom)

Author keywords

Prosthetic joint infections; Total hip replacement; Treatment

Indexed keywords

AMOXICILLIN; AMOXICILLIN PLUS CLAVULANIC ACID; C REACTIVE PROTEIN; CEFTAZIDIME; CEFUROXIME; CIPROFLOXACIN; CLINDAMYCIN; FLUCLOXACILLIN; FUSIDIC ACID; GENTAMICIN; LINEZOLID; MINOCYCLINE; MOXIFLOXACIN; PENICILLIN G; RIFAMPICIN; VANCOMYCIN;

ADULT; AGED; ALPHA HEMOLYTIC STREPTOCOCCUS; ANTIBIOTIC THERAPY; ARTICLE; BACTERIUM CULTURE; BETA HEMOLYTIC STREPTOCOCCUS; CLINICAL ARTICLE; COAGULASE NEGATIVE STAPHYLOCOCCUS; DRUG EFFICACY; DRUG ERUPTION; DRUG SUBSTITUTION; DRUG WITHDRAWAL; EARLY INTERVENTION; ENTEROCOCCAL INFECTION; ENTEROCOCCUS; FEMALE; FOLLOW UP; FUNCTIONAL STATUS; HIP PROSTHESIS INFECTION; HUMAN; LIVER FUNCTION TEST; MALE; MEDICAL RECORD REVIEW; NEUTROPENIA; PNEUMOCOCCAL INFECTION; PROSTHESIS INFECTION; RECURRENT INFECTION; REIMPLANTATION; REOPERATION; SIDE EFFECT; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS INFECTION; STREPTOCOCCUS INFECTION; STREPTOCOCCUS PNEUMONIAE; STREPTOCOCCUS VIRIDANS INFECTION; TOTAL HIP PROSTHESIS; TOTAL HIP PROSTHESIS INFECTION; TREATMENT DURATION; TREATMENT OUTCOME;

ADMINISTRATION, ORAL; ADULT; AGED; AGED, 80 AND OVER; ANTI-BACTERIAL AGENTS; ARTHROPLASTY, REPLACEMENT, HIP; FEMALE; HIP PROSTHESIS; HUMANS; INFUSIONS, PARENTERAL; MALE; MIDDLE AGED; PROSTHESIS-RELATED INFECTIONS; REOPERATION; RETROSPECTIVE STUDIES; TREATMENT OUTCOME;

EID: 80052886010     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dkr277     Document Type: Article

References (7)

1. Pang-Hsin H, Kuo-Chin H, Po-Cheung L et al. Two-stage revision of infected hip arthroplasty using an antibiotic-loaded spacer: retrospective comparison between short-term and prolonged antibiotic therapy. J Antimicrob Chemother 2009; 64: 392-7.
2. Stockley I, Mockford BJ, Hoad-Reddick A et al. The use of two-stage exchange arthroplasty with depot antibiotics in the absence of long-term antibiotic therapy in infected total hip replacement. J Bone Joint Surg 2008; 90B: 145-8.
3. Bernard L, Legout L, Zürcher-Pfund L et al. Six weeks of antibiotic treatment is sufficient following surgery for septic arthroplasty. J Infect 2010; 61: 125-32.
4. Bejon P, Berendt A, Atkins BL et al. Two-stage revision for prosthetic joint infection: predictors of outcome and the role of reimplantation microbiology. J Antimicrob Chemother 2010; 65: 569-75.
5. Andrews JM for the BSAC Working Party on Susceptibility Testing. BSAC standardized disc susceptibility testing method (version 5). J Antimicrob Chemother 2006; 58: 511-29.
6. Atkins BL, Athanasou N, Deeks J et al. Prospective evaluation of criteria for microbiological diagnosis of prosthetic joint infection at revision arthroplasty. J Clin Microbiol 1998; 36: 2932-9.
7. Zappe B, Graf S, Ochsner PE et al. Proprionibacterium spp. in prosthetic joint infections: a diagnostic challenge. Arch Orthop Trauma Surg 2008; 128: 1039-46.