Efficacy of prolonged valganciclovir therapy for congenital cytomegalovirus infection

Journal of Infection and Chemotherapy

Volumn 17, Issue 4, 2011, Pages 538-540

  Kashiwagi, Yasuyo ^a   Kawashima, Hisashi ^a   Nakajima, Junya ^a   Ishida, Yu ^a   Nishimata, Shigeo ^a   Miyajima, Tasuku ^a   Takekuma, Kouji ^a   Hoshika, Akinori ^a   Inoue, Naoki ^b  

^a TOKYO MEDICAL UNIVERSITY   (Japan)

^b NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

Author keywords

Congenital infection; Cytomegalovirus (CMV); Magnetic resonance (MR) imaging; Valganciclovir (VGCV)

Indexed keywords

IMMUNOGLOBULIN M; VALGANCICLOVIR;

ABSENCE OF SIDE EFFECTS; ARTICLE; ATROPHY; BRAIN VENTRICLE DILATATION; CASE REPORT; CHRONIC DRUG ADMINISTRATION; CLINICAL EVALUATION; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTION; DISEASE ASSOCIATION; DISEASE SEVERITY; DRUG EFFICACY; EVOKED BRAIN STEM AUDITORY RESPONSE; HEARING IMPAIRMENT; HUMAN; LIMIT OF DETECTION; MALE; NEWBORN; NUCLEAR MAGNETIC RESONANCE IMAGING; POLYMERASE CHAIN REACTION; RELAPSE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TREATMENT DURATION; VIRUS DETECTION; VIRUS LOAD;

EID: 80052868342     PISSN: 1341321X     EISSN: 14377780     Source Type: Journal    
DOI: 10.1007/s10156-010-0204-z     Document Type: Article

References (11)

1. DW Kimberlin CY Lin PJ Sánchez GJ Demmler W Dankner M Shelton RF Jacobs W Vaudry RF Pass JM Kiell SJ Soong RJ Whitley National Institute of Allergy and Infectious Diseases Collaborative Antiviral Study Group 2003 Effect of ganciclovir therapy on hearing in symptomatic congenital cytomegalovirus disease involving the central nervous system: a randomized, controlled trial J Pediatr 143 16 25 12915819 10.1016/S0022-3476(03)00192-6 1:CAS:528: DC%2BD3sXmt1egsLo%3D (Pubitemid 36928564)
2. SE Oliver GA Cloud PJ Sánchez GJ Demmler W Dankner M Shelton RF Jacobs W Vaudry RF Pass SJ Soong RJ Whitley DW Kimberlin National Institute of Allergy, Infectious Diseases Collaborative Antiviral Study Group 2009 Neurodevelopmental outcomes following ganciclovir therapy in symptomatic congenital cytomegalovirus infections involving the central nervous system J Clin Virol 46 22 26 10.1016/j.jcv.2009.08.012
3. H Ogawa T Suzutani Y Baba S Koyano N Nozawa K Ishibashi K Fujieda N Inoue K Omori 2007 Etiology of severe sensorineural hearing loss in children: independent impact of congenital cytomegalovirus infection and GJB2 mutations J Infect Dis 195 782 788 17299707 10.1086/511981 1:CAS:528:DC%2BD2sXjvVSju7Y%3D (Pubitemid 46363922)
4. Inoue N. Chapter 84 Human herpesvirus 5 (cytomegalovirus). In: Liu D, editor. Molecular detection of human viral pathogens. Boca Raton: Taylor & Francis/CRC Press; 2010. p 952.
5. L Galli A Novelli E Chiappini P Gervaso MI Cassetta S Fallani M de Martino 2007 Valganciclovir for congenital CMV infection: a pilot study on plasma concentration in newborns and infants Pediatr Infect Dis J 26 451 453 17468661 10.1097/01.inf.0000261111.90075.4d (Pubitemid 46789332)
6. Enjoji M, Goya N, Kurokawa T. Enjoji-shiki Nyuyouji Bunsekiteki Kensahyou. Tokyo: Keioutusin; 1992.
7. G Lombardi F Garofoli P Villani M Tizzoni M Angelini M Cusato L Bollani A De Silvestri M Regazzi M Stronati 2009 Oral valganciclovir treatment in newborns with symptomatic congenital cytomegalovirus infection Eur J Clin Microbiol Infect Dis 28 1465 1470 19763643 10.1007/s10096-009-0806-5 1:CAS:528:DC%2BD1MXhtlyhur3K
8. N Tanaka-Kitajima N Sugaya T Futatani H Kanegane C Suzuki M Oshiro M Hayakawa M Futamura T Morishima H Kimura 2005 Ganciclovir therapy for congenital cytomegalovirus infection in six infants Pediatr Infect Dis J 24 782 785 16148844 10.1097/01.inf.0000177280.28694.00 (Pubitemid 41324886)
9. MS Van der Knaap G Vermeulen F Barkhof AA Hart JG Loeber JF Weel 2004 Pattern of white matter abnormalities at MR imaging: use of polymerase chain reaction testing of Guthrie cards to link pattern with congenital cytomegalovirus infection Radiology 230 529 536 14752192 10.1148/radiol. 2302021459 (Pubitemid 38133818)
10. K Shoji N Ito Y Ito N Inoue S Adachi T Fujimaru T Nakamura S Nishina N Azuma A Saitoh 2010 Is a 6-week course of ganciclovir therapy effective for chorioretinitis in infants with congenital cytomegalovirus infection? J Pediatr 157 331 333 20400108 10.1016/j.jpeds.2010.02.020
11. Collaborative Antiviral Study Group Web page. http://www.casg.uab.edu/. Accessed 5 March 2010.