Transient supplementation of anabolic growth factors rapidly stimulates matrix synthesis in engineered cartilage

Annals of Biomedical Engineering

Volumn 39, Issue 10, 2011, Pages 2491-2500

  Ng, Kenneth W ^c   O'Conor, Christopher J ^a   Kugler, Lindsay E ^a   Cook, James L ^b   Ateshian, Gerard A ^a   Hung, Clark T ^a  

^a Fu Foundation School of Engineering and Applied Science   (United States)

^b University of Missouri   (United States)

^c HOSPITAL FOR SPECIAL SURGERY   (United States)

Author keywords

Agarose; Chondrocyte; Mechanical testing; Osteoarthritis; Tissue engineering

Indexed keywords

AGAROSE; BIOCHEMICAL PROPERTIES; BOVINE CHONDROCYTES; CHONDROCYTES; CHONDROGENIC; COLLAGEN CONTENT; CONTINUOUS EXPOSURE; ENGINEERED CARTILAGE; GLYCOSAMINOGLYCANS; GROWTH FACTOR; IN-VITRO; MATRIX SYNTHESIS; OSTEOARTHRITIS; STATISTICAL DIFFERENCES; TEMPORAL APPLICATIONS; TISSUE PROPERTIES; YOUNG'S MODULUS;

BIOMECHANICS; BODY FLUIDS; CARTILAGE; MECHANICAL TESTING; PEPTIDES; TISSUE; TISSUE ENGINEERING;

MECHANICAL PROPERTIES;

COLLAGEN; GLYCOSAMINOGLYCAN; SEPHAROSE; SIGNAL PEPTIDE; SOMATOMEDIN C; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA3;

ANIMAL; ARTICLE; ARTICULAR CARTILAGE; CARTILAGE CELL; CATTLE; CELL CULTURE; CHONDROGENESIS; COMPRESSIVE STRENGTH; CYTOLOGY; HYDROGEL; METABOLISM; METHODOLOGY; PHYSIOLOGY; TISSUE ENGINEERING; YOUNG MODULUS;

ANIMALS; CARTILAGE, ARTICULAR; CATTLE; CELLS, CULTURED; CHONDROCYTES; CHONDROGENESIS; COLLAGEN; COMPRESSIVE STRENGTH; ELASTIC MODULUS; GLYCOSAMINOGLYCANS; HYDROGEL; INSULIN-LIKE GROWTH FACTOR I; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; SEPHAROSE; TISSUE ENGINEERING; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA3;

EID: 80052856280     PISSN: 00906964     EISSN: 15739686     Source Type: Journal    
DOI: 10.1007/s10439-011-0356-8     Document Type: Article

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