In vitro modulation of caprine monocyte immune functions by ω-3 polyunsaturated fatty acids

Veterinary Journal

Volumn 189, Issue 3, 2011, Pages 353-355

  Lecchi, Cristina ^a   Invernizzi, Guido ^a   Agazzi, Alessandro ^a   Ferroni, Mariella ^a   Pisani, Laura Francesca ^a   Savoini, Giovanni ^a   Ceciliani, Fabrizio ^a  

^a UNIVERSITY OF MILAN   (Italy)

Author keywords

Goat; Monocytes; Phagocytosis; Polyunsaturated fatty acids; Reactive oxygen species

Indexed keywords

NORLEUCINE; OMEGA 3 FATTY ACID; REACTIVE OXYGEN METABOLITE;

ARTICLE; CELL VIABILITY; CONCENTRATION RESPONSE; GOAT DISEASE; IMMUNE SYSTEM; IN VITRO STUDY; MEMBRANE FLUIDITY; MOLECULAR DYNAMICS; MONOCYTE; NONHUMAN; PHAGOCYTOSIS; UPREGULATION;

ANIMALS; DOCOSAHEXAENOIC ACIDS; EICOSAPENTAENOIC ACID; GOATS; MONOCYTES; PHAGOCYTOSIS; REACTIVE OXYGEN SPECIES; RESPIRATORY BURST;

CAPRA; CAPRA HIRCUS;

EID: 80052833111     PISSN: 10900233     EISSN: 15322971     Source Type: Journal    
DOI: 10.1016/j.tvjl.2010.09.001     Document Type: Article

References (7)

1. Agazzi A., Cattaneo D., Dell'Orto V., Moroni P., Bonizzi L., Pasotto D., Bronzo V., Savoini G. Effect of administration of fish oil on aspects of cell-mediated immune response in periparturient dairy goats. Small Ruminant Research 2004, 55:77-83.
2. Calder P.C. Immunomodulation by omega-3 fatty acids. Prostaglandins, Leukotrienes and Essential Fatty Acids 2007, 77:327-335.
3. Calder P.C., Bond J.A., Harvey D.J., Gordon S., Newsholme E.A. Uptake and incorporation of saturated and unsaturated fatty acids into macrophage lipids and their effect upon macrophage adhesion and phagocytosis. Biochemical Journal 1990, 269:807-814.
4. Ceciliani F., Pocacqua V., Miranda-Ribera A., Bronzo V., Lecchi C., Sartorelli P. α1-acid glycoprotein modulates apoptosis in bovine monocytes. Veterinary Immunology and Immunopathology 2007, 116:145-152.
5. Hwang Z.H., Hii C.S., Rathjen D.A., Poulos A., Murray A.W., Ferrante A. n-6 and n-3 polyunsaturated fatty acids stimulate translocation of protein kinase Cα, -βI, -βII and -ε and enhance agonist-induced NADPH oxidase in macrophages. Biochemical Journal 1997, 325:553-557.
6. Pisani L.F., Lecchi C., Invernizzi G., Sartorelli P., Savoini G., Ceciliani F. In vitro modulatory effect of ω-3 polyunsaturated fatty acid (EPA and DHA) on phagocytosis and ROS production of goat neutrophils. Veterinary Immunology and Immunopathology 2009, 131:79-85.
7. Schönfeld P., Wojtczak L. Fatty acids as modulators of the cellular production of reactive oxygen species. Free Radical Biology and Medicine 2008, 1767:1032-1040.