Predicting neurally mediated syncope based on pulse arrival time: Algorithm development and preliminary results

Journal of Cardiovascular Electrophysiology

Volumn 22, Issue 9, 2011, Pages 1042-1048

  Meyer, Christian ^a   Morren, Geert ^b   Muehlsteff, Jens ^b   Heiss, Christian ^a   Lauer, Thomas ^a   Schauerte, Patrick ^c   Rassaf, Tienush ^a   Purerfellner, Helmut ^d   Kelm, Malte ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b PHILIPS RESEARCH LABORATORIES   (Germany)

^c RWTH AACHEN UNIVERSITY   (Germany)

^d ELISABETHINEN HOSPITAL   (Austria)

Author keywords

autonomic nervous system; neurally mediated syncope; prediction; pulse arrival time; pulse wave; tilt table testing

Indexed keywords

ADULT; ALGORITHM; ARTICLE; CLINICAL ARTICLE; DIZZINESS; FEMALE; HEART RATE; HUMAN; MALE; NEURALLY MEDIATED SYNCOPE; ORTHOSTATIC STRESS; PREDICTION; PRIORITY JOURNAL; PULSE WAVE; STANDING; SYNCOPE;

ADULT; AGED; ALGORITHMS; FEMALE; HEART RATE; HUMANS; MALE; MIDDLE AGED; PREDICTIVE VALUE OF TESTS; PULSE; SYNCOPE, VASOVAGAL; TILT-TABLE TEST; TIME FACTORS; YOUNG ADULT;

EID: 80052823832     PISSN: 10453873     EISSN: 15408167     Source Type: Journal    
DOI: 10.1111/j.1540-8167.2011.02030.x     Document Type: Article

References (22)

1. Chen-Scarabelli C, Scarabelli TM,: Neurocardiogenic syncope. BMJ 2004; 329: 336-341. (Pubitemid 39062306)
2. Julu PO, Cooper VL, Hansen S, Hainsworth R,: Cardiovascular regulation in the period preceding vasovagal syncope in conscious humans. J Physiol 2003; 549 (Pt 1): 299-311. (Pubitemid 36626416)
3. Shen WK, Low PA, Rea RF, Lohse CM, Hodge DO, Hammill SC,: Distinct hemodynamic profiles in patients with vasovagal syncope: A heterogeneous population. J Am Coll Cardiol 2000; 35: 1470-1477. (Pubitemid 30307489)
4. Virag N, Sutton R, Vetter R, Markowitz T, Erickson M,: Prediction of vasovagal syncope from heart rate and blood pressure trend and variability: Experience in 1,155 patients. Heart Rhythm 2007; 4: 1375-1382. (Pubitemid 47595223)
5. Chan GS, Middleton PM, Celler BG, Wang L, Lovell NH,: Change in pulse transit time and pre-ejection period during head-up tilt-induced progressive central hypovolaemia. J Clin Monit Comput 2007; 21: 283-293. (Pubitemid 47399694)
6. Muehlsteff J, Aubert XL, Schuett M,: Cuffless estimation of systolic blood pressure for short effort bicycle tests: The prominent role of the pre-ejection period. Conf Proc IEEE Eng Med Biol Soc 2006; 1: 5088-5092. (Pubitemid 46521059)
7. Payne RA, Symeonides CN, Webb DJ, Maxwell SR,: Pulse transit time measured from the ECG: An unreliable marker of beat-to-beat blood pressure. J Appl Physiol 2006; 100: 136-141. (Pubitemid 43671100)
8. Rassaf T, Muehlsteff J, Such O, Kelm M, Meyer C,: The pulse arrival time approach for non-invasive hemodynamic monitoring in low-acuity settings. Med Sci Monit 2010; 16: MT83-MT87.
9. Meyer C, Heiss C, Drexhage C, Kehmeier ES, Balzer J, Muhlfeld A, Merx MW, Lauer T, Kuhl H, Floege J, Kelm M, Rassaf T,: Hemodialysis-induced release of hemoglobin limits nitric oxide bioavailability and impairs vascular function. J Am Coll Cardiol 2010; 55: 454-459.
10. Meyer C, Rana OR, Saygili E, Gemein C, Becker M, Nolte KW, Weis J, Schimpf T, Knackstedt C, Mischke K, Hoffmann R, Kelm M, Pauza D, Schauerte P,: Augmentation of left ventricular contractility by cardiac sympathetic neural stimulation. Circulation 2010; 121: 1286-1294.
11. Meyer C, Rana OR, Saygili E, Ozuyaman B, Latz K, Rassaf T, Kelm M, Schauerte P,: Hyperoxic chemoreflex sensitivity is impaired in patients with neurocardiogenic syncope. Int J Cardiol 2010; 142: 38-43.
12. Moya A, Sutton R, Ammirati F, Blanc JJ, Brignole M, Dahm JB, Deharo JC, Gajek J, Gjesdal K, Krahn A, Massin M, Pepi M, Pezawas T, Granell RR, Sarasin F, Ungar A, van Dijk JG, Walma EP, Wieling W, Abe H, Benditt DG, Decker WW, Grubb BP, Kaufmann H, Morillo C, Olshansky B, Parry SW, Sheldon R, Shen WK, Vahanian A, Auricchio A, Bax J, Ceconi C, Dean V, Filippatos G, Funck-Brentano C, Hobbs R, Kearney P, McDonagh T, McGregor K, Popescu BA, Reiner Z, Sechtem U, Sirnes PA, Tendera M, Vardas P, Widimsky P, Auricchio A, Acarturk E, Andreotti F, Asteggiano R, Bauersfeld U, Bellou A, Benetos A, Brandt J, Chung MK, Cortelli P, Da CA, Extramiana F, Ferro J, Gorenek B, Hedman A, Hirsch R, Kaliska G, Kenny RA, Kjeldsen KP, Lampert R, Molgard H, Paju R, Puodziukynas A, Raviele A, Roman P, Scherer M, Schondorf R, Sicari R, Vanbrabant P, Wolpert C, Zamorano JL,: Guidelines for the diagnosis and management of syncope (version 2009): The Task Force for the Diagnosis and Management of Syncope of the European Society of Cardiology (ESC). Eur Heart J 2009; 30: 2631-2671.
13. Hindricks G, Pokushalov E, Urban L, Taborsky M, Kuck KH, Lebedev D, Rieger G, Purerfellner H,: Performance of a new leadless implantable cardiac monitor in detecting and quantifying atrial fibrillation: results of the XPECT trial. Circ Arrhythm Electrophysiol 2010; 3: 141-147.
14. Furlan R, Piazza S, Dell'Orto S, Barbic F, Bianchi A, Mainardi L, Cerutti S, Pagani M, Malliani A,: Cardiac autonomic patterns preceding occasional vasovagal reactions in healthy humans. Circulation 1998; 98: 1756-1761. (Pubitemid 28492496)
15. Pruvot E, Vesin JM, Schlaepfer J, Fromer M, Kappenberger L,: Autonomic imbalance assessed by heart rate variability analysis in vasovagal syncope. Pacing Clin Electrophysiol 1994; 17 (11 Pt 2): 2201-2206. (Pubitemid 24362975)
16. Morillo CA, Eckberg DL, Ellenbogen KA, Beightol LA, Hoag JB, Tahvanainen KU, Kuusela TA, Diedrich AM,: Vagal and sympathetic mechanisms in patients with orthostatic vasovagal syncope. Circulation 1997; 96: 2509-2513. (Pubitemid 27451338)
17. Pitzalis M, Massari F, Guida P, Iacoviello M, Mastropasqua F, Rizzon B, Forleo C, Rizzon P,: Shortened head-up tilting test guided by systolic pressure reductions in neurocardiogenic syncope. Circulation 2002; 105: 146-148. (Pubitemid 34084309)
18. Pitzalis M, Parati G, Massari F, Guida P, Di RM, Rizzon B, Castiglioni P, Iacoviello M, Mastropasqua F, Rizzon P,: Enhanced reflex response to baroreceptor deactivation in subjects with tilt-induced syncope. J Am Coll Cardiol 2003; 41: 1167-1173. (Pubitemid 36384905)
19. Mallat Z, Vicaut E, Sangare A, Verschueren J, Fontaine G, Frank R,: Prediction of head-up tilt test result by analysis of early heart rate variations. Circulation 1997; 96: 581-584. (Pubitemid 27329437)
20. Moak JP, Bailey JJ, Makhlouf FT,: Simultaneous heart rate and blood pressure variability analysis. Insight into mechanisms underlying neurally mediated cardiac syncope in children. J Am Coll Cardiol 2002; 40: 1466-1474. (Pubitemid 35192873)
21. Muehlsteff J, Aubert XA, Morren G,: Continuous cuff-less blood pressure monitoring based on the pulse arrival time approach: The impact of posture. Conf Proc IEEE Eng Med Biol Soc 2008; 2008: 1691-1694.
22. Allen J,: Photoplethysmography and its application in clinical physiological measurement. Physiol Meas 2007; 28: R1-R39. (Pubitemid 46646334)