Myocardial contrast echocardiography in coronary artery disease

Journal of Cardiovascular Echography

Volumn 21, Issue 1, 2011, Pages 1-11

  Chadderdon, Scott M ^a   Kaul, Sanjiv ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

Contrast media; Coronary artery disease; Echocardiography; Myocardial blood flow; Myocardial viability

Indexed keywords

ACUTE CORONARY SYNDROME; CONTRAST ECHOCARDIOGRAPHY; CORONARY ARTERY BLOOD FLOW; CORONARY ARTERY DISEASE; EMERGENCY TREATMENT; HEART MUSCLE BLOOD FLOW; HUMAN; REVIEW; THORAX PAIN;

EID: 80052822975     PISSN: 22114122     EISSN: 2347193X     Source Type: Journal    
DOI: 10.1016/j.jcecho.2011.03.001     Document Type: Review

References (75)

1. Gramiak R, Shah PM. Echocardiography of the aortic root. Invest Radiol 1968;3:356-66.
2. Feinstein SB, Ten Cate FJ, Zwehl W, Ong K, Maurer G, Tei C, et al. Twodimensional contrast echocardiography: in vitro development and quantitative analysis of echo contrast agents. J Am Coll Cardiol 1984;3:14-20. (Pubitemid 14219948)
3. Moore CA, Smucker ML, Kaul S. Myocardial contrast echocardiography in humans: I. Safety-a comparison with routine coronary angiography. J Am Coll Cardiol 1986;8:1066-72. (Pubitemid 16009091)
4. KellerMW, Glasheen WP, Smucker ML, Burwell LR, Watson DD, Kaul S. Myocardial contrast echocardiography in humans: II. Assessment of coronary blood flow reserve. J Am Coll Cardiol 1988;12:925-35.
5. Keller MW, Glasheen WP, Teja K, Gear A, Kaul S. Myocardial contrast echocardiography without significant hemodynamic effects or reactive hyperemia: a major advantage in the imaging of myocardial perfusion. J Am Coll Cardiol 1988;12:1039-47.
6. Lindner JR, Dent JM, Moos S, Jayaweera AR, Kaul S. Enhancement of left ventricular cavity opacification by harmonic imaging after venous injection of Albunex. J Am Coll Cardiol 1997;79:1657-62. (Pubitemid 27339477)
7. Skyba DM, Camarano G, Goodman NC, Price RJ, Skalak TC, Kaul S. Hemodynamic characteristics, myocardial kinetics, and microvascular rheology of FS-069, a second-generation echocardiographic contrast agent capable of producing myocardial opacification from a venous injection. J Am Coll Cardiol 1996;28:1292-300. (Pubitemid 26377008)
8. Lindner JR, Firschke C, Wei K, Goodman NC, Skyba DM, Kaul S. Myocardial perfusion characteristics and hemodynamic profile of MRX- 115, a venous echocardiographic contrast agent during acute myocardial infarction. J Am Soc Echocardiogr 1998;11:36-46. (Pubitemid 28158527)
9. KellerMW, Segal SS, Kaul S, Duling B. The behavior of sonicated albumin microbubbles within the microcirculation: a basis for their use during myocardial contrast echocardiography. Circ Res 1989;65:458-67. (Pubitemid 19194632)
10. Lindner JR, Song J, Jayaweera AR, Sklenar J, Kaul S. Microvascular rheology of definity microbubbles after intra-arterial and intravenous administration. J Am Soc Echocardiogr 2002;15:396-403. (Pubitemid 46002653)
11. Jayaweera AR, Edwards N, Glasheen WP, Villanueva FS, Abbott RD, Kaul S. In-vivo myocardial kinetics of air-filled albumin microbubbles during myocardial contrast echocardiography: comparison with radiolabeled red blood cells. Circ Res 1994;74:1157-65. (Pubitemid 24176911)
12. Wei K, Skyba DM, Firschke C, Lindner JR, Jayaweera AR, Kaul S. Interaction between microbubbles and ultrasound: in vitro and in vivo observations. J Am Coll Cardiol 1997;29:1081-8. (Pubitemid 27149585)
13. Uhlendorf V, Hoffman C. Nonlinear acoustical response of coated microbubbles in diagnostic ultrasound. IEEE Proc 1994;3:1559-62.
14. Shi W, Forsberg F. Ultrasonic characterization of the nonlinear properties of contrast microbubbles. Ultrasound Med Biol 2000;26:93-104. (Pubitemid 30045527)
15. Kaul S. Instrumentation for Contrast Echocardiography: Technology and Techniques. J Am Coll Cardiol 2002;90(Suppl):8J-14J. (Pubitemid 35346861)
16. Wei K, Jayaweera AR, Firoozan S, Linka A, Skyba DM, Kaul S. Quantification of myocardial blood flow with ultrasound-induced destruction of microbubbles administered as a constant venous infusion. Circulation 1998;97:473-83. (Pubitemid 28090220)
17. Porter TR, Li S, Kricsfeld D, Armbruster RW. Detection of myocardial perfusion in multiple echocardiographic windows with one intravenous injection of microbubbles using transient response second harmonic imaging. J Am Coll Cardiol 1997;29:791-9. (Pubitemid 27128253)
18. Kaul S, Senior R, Dittrich H, Raval U, Khattar R, Lahiri A. Detection of coronary artery disease with myocardial contrast echocardiography: comparison with 99mTc-sestamibi single-photon emission computed tomography. Circulation 1997;96:785-92. (Pubitemid 27329610)
19. Kaul S, Senior R, Firschke C, Wang X, Lindner JR, Villanueva FS, et al. Incremental value of cardiac imaging in patients presenting to the emergency department with chest pain and without ST-segment elevation: A multicenter study. Am Heart J 2004;148:129-36. (Pubitemid 38900492)
20. Kaul S. Coronary angiography cannot be used to assess myocardial perfusion in patients undergoing reperfusion for acute myocardial infarction. Heart 2001;86:483-4. (Pubitemid 32999851)
21. Villanueva FS, Glasheen WP, Sklenar J, Kaul S. Characterization of spatial patterns of flow within the reperfused myocardium using myocardial contrast echocardiography: implications in deter-mining the extent of myocardial salvage. Circulation 1993;88:2596-606. (Pubitemid 23360184)
22. Villanueva FS, Camarano G, Ismail S, Goodman NC, Sklenar J, Kaul S. Coronary reserve abnormalities during post-infarct reperfusion: implications for the timing of myocardial contrast echocardiography to assess myocardial viability. Circulation 1996;94:748-54. (Pubitemid 26289232)
23. Ragosta M, Camarano GP, Kaul S, Powers E, Sarembock IJ, Gimple LW. Microvascular integrity indicates myocellular viability in patients with recent myocardial infarction: new insights using myocardial contrast echocardiography. Circulation 1994;89:2562-9.
24. Sakuma T, Hayashi Y, Sumii K, Imazu M, Yamakido M. Prediction of short- and intermediate-term prognoses of patients with acute myocardial infarction using myocardial contrast echocardiography one day after recanalization. J Am Coll Cardiol 1998;32:890-7. (Pubitemid 28459575)
25. Kloner RA, Ganote CE, Jennings RB. The "no-reflow" phenomenon after temporary coronary occlusion in the dog. J Clinical Invest 1974;54:1496-508.
26. Kloner RA, Rude RE, Carlson N, Maroko PR, DeBoer LW, Braunwald E. Ultrastructural evidence of microvascular damage and myocardial cell injury after coronary artery occlusion: which comes first? Circulation 1980;62:945-52. (Pubitemid 11225959)
27. Ambrosio G, Weisman HF, Mannisi JA, Becker LC. Progressive impairment of regional myocardial perfusion after initial restoration of post ischemic blood flow. Circulation 1989;80:1846-61. (Pubitemid 20031716)
28. Kloner RA. Does reperfusion injury exist in humans? J Am Coll of Cardiol 1993;21:537-45. (Pubitemid 23047942)
29. Davies MJ, Thomas AC, Knapman PA, Hangartner JR. Intramyocardial platelet aggregation in patients with unstable angina suffering sudden ischemic cardiac death. Circulation 1986;73:418-27. (Pubitemid 16133019)
30. Frink RJ, Rooney Jr PA, Towbridge JO, Rose JP. Coronary thrombosis and platelet/fibrin microemboli in death associated with acute myocardial infarction. Br Heart J 1988;59:196-200. (Pubitemid 18045121)
31. Yao S-K, Ober JC, McNatt J, Benedict CR, Rosolowsky M, Anderson HV, et al. ADP plays an important role in mediating platelet aggregation and cyclic flow variations in vivo in stenosed and endothelium-injured canine coronary arteries. Circ Res 1992;70:39-48.
32. Hirsh PD, Hillis LD, Campbell WB, Firth BG, Willerson JT. Release of prostaglandins and thromboxane into the coronary circulation in patients with ischemic heart disease. N Engl J Med 1981;304:685-91. (Pubitemid 11113827)
33. Kotani J, Nanto S, Mintz GS, Kitakaze M, Ohara T, Morozumi T, et al. Plaque gruel of atheromatous coronary lesion may contribute to the no reflow phenomenon in patients with acute coronary syndrome. Circulation 2002;106:1672-7.
34. Ito H, Okamura A, Iwakura K, Masuyama T, Hori M, Takiuchi S, et al. Myocardial perfusion patterns related to thrombolysis in myocardial infarction perfusion grades after coronary angioplasty in patients with acute anterior wall myocardial infarction. Circulation 1996;93:1993-9. (Pubitemid 26167228)
35. Ito H, Tomooka T, Sakai N, Yu H, Higashino Y, Fuji K, et al. Lack of myocardial perfusion immediately after successful thrombolysis. A predictor of poor recovery of left ventricular function in anterior myocardial infarction. Circulation 1992;85:1699-705.
36. Ito H, Maruyama A, Iwakura K, Takiuchi S, Masuyama T, Hori M, et al. Clinical implications of the "no reflow" phenomenon: a predictor of complications and left ventricular remodeling in reperfused anterior wall myocardial infarction. Circulation 1996;93:223-8. (Pubitemid 26031478)
37. Selker HP, Beshansky JR, Griffith JL, Aufderheide TP, Ballin DS, Bernard SA, et al. Use of the acute cardiac ischemia time-insensitive predictive instrument (ACI-TIPI) to assist with triage of patients with chest pain or other symptoms suggestive of acute cardiac ischemia. A multi-center, controlled clinical trial. Ann Intern Med 1998;129:845-55. (Pubitemid 28549811)
38. Sabia P, Abbott RD, Afrookteh A, Keller MW, Touchstone DA, Kaul S. Importance of two-dimensional echocardiographic assessment of left ventricular systolic function in patients presenting to the emergency room with cardiac-related symptoms. Circulation 1991;84:1615-24.
39. Korosoglou G, Labadze N, Hansen A, Selter C, Giannitsis E, Katus H, et al. Usefulness of real-time myocardial perfusion imaging in the evaluation of patients with first time chest pain. Am J Cardiol 2004;94:1225-31. (Pubitemid 39469938)
40. Rinkevich D, Kaul S, Wang X, Tong KL, Belcik T, Kalvaitis S, et al. Regional left ventricular perfusion and function in patients presenting to the emergency department with chest pain and no ST-segment elevation. Eur Heart J 2005;26:1606-11. (Pubitemid 41389690)
41. Tong KL, Kaul S, Wang X, Rinkevich D, Kalvaitis S, Lepper W, et al. Myocardial contrast echocardiography versus thrombolysis in myocardial infarction score in patients presenting to the emergency department with chest pain and a non-diagnostic electrocardiogram. J Am Coll Cardiol 2005;46:920-7. (Pubitemid 41224817)
42. Wei K, Peters D, Belcik T, Kalvaitis S, Womak L, Rinkevich D, et al. A predictive instrument using contrast echocardiography in patients presenting with chest pain and without ST-segment elevation. J Am Soc Echocardiogr 2010;23:636-42.
43. Wyrick JJ, Kalavaitis S, McConnell J, Rinkevich D, Kaul S, Wei K. Cost efficiency of myocardial contrast echocardiography in patients presenting to the emergency department with chest pain of suspected cardiac origin and a non-diagnostic electrocardiogram. Am J Cardiol 2008;102:649-52.
44. Senior R, Ashrafian H. Detecting acute coronary syndrome in the emergency department: the answer is seeing the heart: why look further? Eur Heart J 2005;26:1606-11.
45. Vannan MA, Narula J. Ischemic versus non-ischemic chest pain in the emergency room. J Am Coll Cardiol 2005;46:928-9. (Pubitemid 41224818)
46. Wei K. Utility Contrast Echocardiography in the Emergency Department. JACC: Cardiovascular Imaging 2010;3:197-203.
47. Ismail S, Jayaweera AR, Goodman NC, Camarano GP, Skyba DM, Kaul S. Detection of coronary stenoses and quantification of the degree and spatial extent of blood flow mismatch during coronary hyperemia with myocardial contrast echocardiography. Circulation 1995;91:821-30.
48. Wei K, Jayaweera AR, Firoozaan S, Linka A, Skyba DM, Kaul S. Basis for detection of stenosis using venous administration of microbubbles during myocardial contrast echocardiography: bolus or continuous infusion? J Am Coll Cardiol 1998;32:252-60. (Pubitemid 28351070)
49. Jayaweera AR, Wei K, Coggins M, Bin JP, Goodman C, Kaul S. Role of capillaries in determining CBF reserve: newinsights using myocardial contrast echocardiography. Am J Physiol-Heart Circ Physiol 1999;277:H2363-72. (Pubitemid 30048158)
50. Wei K, Le E, Bin JP, Coggins M, Jayaweera AR, Kaul S. Mechanism of reversible 99mTc-sestamibi perfusion defects during pharmacologically induced coronary vasodilation. Am J Physiol-Heart Circ Physiol 2001;280:H1896-904.
51. Wei K, Ragosta M, Thorpe J, Coggins M, Moos S, Kaul S. Noninvasive quantification of coronary blood flow reserve in humans using myocardial contrast echocardiography. Circulation 2001;103:2560-5. (Pubitemid 32521965)
52. Bin JP, Pelberg RA, Wei K, Le E, Goodman C, Kaul S. Dobutamine versus dipyridamole for inducing reversible perfusion defects in chronic multivessel coronary artery disease. J Am Coll Cardiol 2002;40:167-74. (Pubitemid 34701393)
53. Villanueva FS, Gertz EW, Csikari M, Pulido G, Fisher D, Sklenar J. Detection of coronary artery stenosis with power Doppler imaging. Circulation 2001;103:2624-30. (Pubitemid 32521975)
54. Heinle SK, Noblin J, Goree-Best P, Mello A, Ravad G, Mull S, et al. Assessment of myocardial perfusion by harmonic power Doppler imaging at rest and during adenosine stress: comparison with 99mTc-sestamibi SPECT imaging. Circulation 2000;102:55-60. (Pubitemid 30430553)
55. Dawson D, Rinkevich D, Belcik T, Jayaweera AR, Rafter P, Kaul S, et al. Measurement of myocardial blood flow velocity reserve with myocardial contrast echocardiography in patients with suspected coronary artery disease: comparison with quantitative gated technetium 99m sestamibi single photon emission computed tomography. J Am Soc Echocardiogr 2003;16:1171-7. (Pubitemid 37371662)
56. Porter TR, Xie F. Myocardial perfusion imaging with contrast ultrasound. JACC: Cardiovascular Imaging 2010;3:176-87.
57. Arnold JR, Karamitsos TD, Pegg TJ, Francis JM, Olszewski R, Searle N, et al. Adenosine stress myocardial contrast echocardiography for the detection of coronary artery disease: a comparison with coronary angiography and cardiac magnetic resonance. JACC: Cardiovascular Imaging 2010;3:934-43.
58. Hauser A, Gangadharan V, Ramos RG, Gordon S, Timmis GC. Sequence of mechanical, electrocardiographic, and clinical effects of repeated coronary occlusion in human beings: echocardiographic observations during coronary angioplasty. J Am Coll Cardiol 1985;5:193-7. (Pubitemid 15174071)
59. Leong-Poi H, Rim SJ, Le E, Fisher NG, Wei K, Kaul S. Perfusion versus function: the ischemic cascade in demand ischemia: implications of singlevessel versus multi-vessel stenosis. Circulation 2002;105:987-92. (Pubitemid 34184579)
60. Dolan MS, Gala SS, Dodla S, Ablemoneim SS, Xie Feng. Cloutier D, et al. Safety and efficacy of commercially available ultrasound contrast agents for rest stress echocardiography. J Am Coll Cardiol 2009;53:32-8.
61. Kemper AJ, O'Boyle JE, Cohen CA, Taylor A, Parisi AF. Hydrogen peroxide contrast echocardiography: Quantification in vivo of myocardial risk area during coronary occlusion and the necrotic area remaining after myocardial reperfusion. Circulation 1984;70:309-17. (Pubitemid 14058250)
62. Ito H, Tomooka T, Sakai N, Yu H, Higashino Y, Fujii K, et al. Lack of myocardial perfusion immediately after successful thrombolysis: A predictor of poor recovery of left ventricular function in anterior myocardial infarction. Circulation 1992;85:1699-705.
63. Sakuma T, Hayashi Y, Sumii K, Imazu M, Yamakido M. Prediction of short-and inter-mediate term prognoses of patients with acute myocardial infarction using myocardial contrast echocardiography one day after recanalization. J Am Coll Cardiol 1998;32:890-7. (Pubitemid 28459575)
64. Villanueva FS, Glasheen WP, Sklenar J, Kaul S. Characterization of spatial patterns of flow within the reperfused myocardium using myocardial contrast echocardiography: implications in determining the extent of myocardial salvage. Circulation 1993;88:2596-606. (Pubitemid 23360184)
65. Janardhanan R, Swinburn JM, Greaves K, Senior R. Usefulness of myocardial contrast echocardiography using low-power continuous imaging early after acute myocardial infarction to predict late functional left ventricular recovery. Am J Cardiol 2003;92:493-7. (Pubitemid 37013397)
66. Dwivedi G, Janardhanan R, Hayat SA, Swinburn JA, Senior R. Prognostic value of myocardial viability detected by myocardial contrast echocardiography early after acute myocardial infarction. J Am Coll Cardiol 2007;50:327-34. (Pubitemid 47058879)
67. Hyat SA, Janardhanan R, Moon JC, Pennell DJ, Senior R. Comparison between myocardial contrast echocardiography and single-photon emission computed tomography for predicting transmurality of acute myocardial infarction. Am J Cardiol 2006;97:1718-21. (Pubitemid 43817859)
68. Sabia PJ, Powers ER, Ragosta M, Sarembock IJ, Burwell LR, Kaul S. An association between collateral blood flow and myocardial viability in patients with recent myocardial infarction. N Engl J Med 1992;372:1825-31. (Pubitemid 23003072)
69. Sabia PJ, Powers ER, Jayaweera AR, Ragosta M, Kaul S. Functional significance of collateral blood flow in patients with recent acute myocardial infarction. A study using myocardial contrast echocardiography. Circulation 1992;85:2080-9.
70. Coggins MP, Le DE, Wei K, Goodman NC, Lindner JR, Kaul S. Noninvasive prediction of ultimate infarct size at the time of acute coronary occlusion based on the extent and magnitude of collateral-derived myocardial blood flow. Circulation 2001;104:2471-7. (Pubitemid 33108383)
71. Shimoni S, Fangogiannis NG, Aggeli CJ, Shan K, Verani MS, Quinones MA, et al. Identification of hibernating myocardium with quantitative intravenous myocardial contrast echocardiography: comparison with dobutamine echocardiography and thallium-201 scintigraphy. Circulation 2003;107:538-44. (Pubitemid 36176801)
72. Shimoni S, Frangogiannis NG, Aggeli CJ, Shan K, Quinones MA, Espada R, et al. Microvascular structural correlates of myocardial contrast echocardiography in patients with coronary artery disease and left ventricular dysfunction: implications for the assessment of myocardial hibernation. Circulation 2002;106:950-6. (Pubitemid 34925329)
73. Senior R, Janardhanan R, Jeetley P, Burden L. Myocardial contrast echocardiography for distinguishing ischemic from nonischemic first-onset acute heart failure: insights into the mechanism of acute heart failure. Circulation 2005;112:1587-93. (Pubitemid 41324520)
74. Main ML, Ryan AC, Davis TE, Albano MP, Kusnetzky LL, Hibbard M. Acute mortality in hospitalized patients undergoing echocardiography with and without an ultrasound contrast agent: multicenter registry results in 4, 300, 966 consecutive patients. Am J Cardiol 2008;102:1742-6.
75. Gaibazzi N, Squeri A, Ardissino D, Reverberi C. Safety of contrast flashreplenishment stress echocardiography in 500 patients with a chest pain episode of undetermined origin within the last 5 days. Eur J Echocardiogr 2009;10:726-32.