-
1
-
-
0032994536
-
Growth hormone therapy in patients with dilated cardiomyopathy: preliminary observations of a pilot study
-
Jose V.J., Zechariah T.U., George P., Jonathan V. Growth hormone therapy in patients with dilated cardiomyopathy: preliminary observations of a pilot study. Indian Heart J Mar-Apr 1999, 51(2):183-185.
-
Indian Heart J
-
-
Jose, V.J.1
Zechariah, T.U.2
George, P.3
Jonathan, V.4
-
2
-
-
0037305044
-
Administration of growth hormone to patients with advanced cardiac heart failure: effects upon left ventricular function, exercise capacity, and neurohormonal status
-
Acevedo M., Corbalan R., Chamorro G., Jalil J., Nazzal C., Campusano C., et al. Administration of growth hormone to patients with advanced cardiac heart failure: effects upon left ventricular function, exercise capacity, and neurohormonal status. Int J Cardiol 2003, 87(2-3):185-191.
-
(2003)
Int J Cardiol
, vol.87
, Issue.2-3
, pp. 185-191
-
-
Acevedo, M.1
Corbalan, R.2
Chamorro, G.3
Jalil, J.4
Nazzal, C.5
Campusano, C.6
-
3
-
-
0030069728
-
Differential cardiac effects of growth hormone and insulin-like growth factor-1 in the rat. A combined in vivo and in vitro evaluation
-
Cittadini A., Stromer H., Katz S.E., Clark R., Moses A.C., Morgan J.P., et al. Differential cardiac effects of growth hormone and insulin-like growth factor-1 in the rat. A combined in vivo and in vitro evaluation. Circulation 1996, 93(4):800-809.
-
(1996)
Circulation
, vol.93
, Issue.4
, pp. 800-809
-
-
Cittadini, A.1
Stromer, H.2
Katz, S.E.3
Clark, R.4
Moses, A.C.5
Morgan, J.P.6
-
4
-
-
0037429649
-
Neuregulins: functions, forms, and signaling strategies
-
Falls D.L. Neuregulins: functions, forms, and signaling strategies. Exp Cell Res 2003, 284(1):14-30.
-
(2003)
Exp Cell Res
, vol.284
, Issue.1
, pp. 14-30
-
-
Falls, D.L.1
-
5
-
-
0028785406
-
Aberrant neural and cardiac development in mice lacking the ErbB4 neuregulin receptor [see comments]
-
Gassmann M., Casagranda F., Orioli D., Simon H., Lai C., Klein R., et al. Aberrant neural and cardiac development in mice lacking the ErbB4 neuregulin receptor [see comments]. Nature 1995, 378(6555):390-394.
-
(1995)
Nature
, vol.378
, Issue.6555
, pp. 390-394
-
-
Gassmann, M.1
Casagranda, F.2
Orioli, D.3
Simon, H.4
Lai, C.5
Klein, R.6
-
6
-
-
0028914037
-
Wortmannin inhibits insulin-stimulated but not contraction-stimulated glucose transport activity in skeletal muscle
-
Lee A.D., Hansen P.A., Holloszy J.O. Wortmannin inhibits insulin-stimulated but not contraction-stimulated glucose transport activity in skeletal muscle. FEBS Lett 1995, 361(1):51-54.
-
(1995)
FEBS Lett
, vol.361
, Issue.1
, pp. 51-54
-
-
Lee, A.D.1
Hansen, P.A.2
Holloszy, J.O.3
-
7
-
-
0028827104
-
Multiple essential functions of neuregulin in development
-
Meyer D., Birchmeier C. Multiple essential functions of neuregulin in development. Nature 1995, 378(6555):386-390.
-
(1995)
Nature
, vol.378
, Issue.6555
, pp. 386-390
-
-
Meyer, D.1
Birchmeier, C.2
-
8
-
-
0032573183
-
Domain-specific gene disruption reveals critical regulation of neuregulin signaling by its cytoplasmic tail
-
Liu X., Hwang H., Cao L., Buckland M., Cunningham A., Chen J., et al. Domain-specific gene disruption reveals critical regulation of neuregulin signaling by its cytoplasmic tail. Proc Natl Acad Sci USA 1998, 95(22):13024-13029.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, Issue.22
, pp. 13024-13029
-
-
Liu, X.1
Hwang, H.2
Cao, L.3
Buckland, M.4
Cunningham, A.5
Chen, J.6
-
9
-
-
0028884413
-
Requirement for neuregulin receptor erbB2 in neural and cardiac development
-
Lee K.F., Simon H., Chen H., Bates B., Hung M.C., Hauser C. Requirement for neuregulin receptor erbB2 in neural and cardiac development. Nature 1995, 378(6555):394-398.
-
(1995)
Nature
, vol.378
, Issue.6555
, pp. 394-398
-
-
Lee, K.F.1
Simon, H.2
Chen, H.3
Bates, B.4
Hung, M.C.5
Hauser, C.6
-
10
-
-
0032562770
-
Neuregulins promote survival and growth of cardiac myocytes. Persistence of ErbB2 and ErbB4 expression in neonatal and adult ventricular myocytes
-
Zhao Y.Y., Sawyer D.R., Baliga R.R., Opel D.J., Han X., Marchionni M.A., et al. Neuregulins promote survival and growth of cardiac myocytes. Persistence of ErbB2 and ErbB4 expression in neonatal and adult ventricular myocytes. J Biol Chem 1998, 273(17):10261-10269.
-
(1998)
J Biol Chem
, vol.273
, Issue.17
, pp. 10261-10269
-
-
Zhao, Y.Y.1
Sawyer, D.R.2
Baliga, R.R.3
Opel, D.J.4
Han, X.5
Marchionni, M.A.6
-
11
-
-
27344447301
-
Neuregulin-1alpha and beta isoform expression in cardiac microvascular endothelial cells and function in cardiac myocytes in vitro
-
Cote G.M., Miller T.A., Lebrasseur N.K., Kuramochi Y., Sawyer D.B. Neuregulin-1alpha and beta isoform expression in cardiac microvascular endothelial cells and function in cardiac myocytes in vitro. Exp Cell Res 2005, 311(1):135-146.
-
(2005)
Exp Cell Res
, vol.311
, Issue.1
, pp. 135-146
-
-
Cote, G.M.1
Miller, T.A.2
Lebrasseur, N.K.3
Kuramochi, Y.4
Sawyer, D.B.5
-
12
-
-
79955052182
-
Activation of the neuregulin/ErbB system during physiological ventricular remodeling in pregnancy
-
Lemmens K., Doggen K., De Keulenaer G.W. Activation of the neuregulin/ErbB system during physiological ventricular remodeling in pregnancy. Am J Physiol Heart Circ Physiol 2011, 300(3):H931-H942.
-
(2011)
Am J Physiol Heart Circ Physiol
, vol.300
, Issue.3
-
-
Lemmens, K.1
Doggen, K.2
De Keulenaer, G.W.3
-
13
-
-
10944236872
-
Cardiac endothelial cells regulate ROS-induced cardiomyocyte apoptosis through neuregulin-1beta /erbB4 signaling
-
Kuramochi Y., Cote G.M., Guo X., LeBrasseur N.K., Cui L., Liao R., et al. Cardiac endothelial cells regulate ROS-induced cardiomyocyte apoptosis through neuregulin-1beta /erbB4 signaling. J Biol Chem 2004, 279(49):51141-51147.
-
(2004)
J Biol Chem
, vol.279
, Issue.49
, pp. 51141-51147
-
-
Kuramochi, Y.1
Cote, G.M.2
Guo, X.3
LeBrasseur, N.K.4
Cui, L.5
Liao, R.6
-
14
-
-
0033393696
-
Neuregulin activation of ErbB receptors in vascular endothelium leads to angiogenesis
-
Russell K.S., Stern D.F., Polverini P.J., Bender J.R. Neuregulin activation of ErbB receptors in vascular endothelium leads to angiogenesis. Am J Physiol Heart Circ Physiol 1999, 277(6 Pt 2):H2205-H2211.
-
(1999)
Am J Physiol Heart Circ Physiol
, vol.277
, Issue.6 PART 2
-
-
Russell, K.S.1
Stern, D.F.2
Polverini, P.J.3
Bender, J.R.4
-
15
-
-
0035869407
-
Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2
-
Slamon D.J., Leyland-Jones B., Shak S., Fuchs H., Paton V., Bajamonde A., et al. Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2. N Engl J Med 2001, 344(11):783-792.
-
(2001)
N Engl J Med
, vol.344
, Issue.11
, pp. 783-792
-
-
Slamon, D.J.1
Leyland-Jones, B.2
Shak, S.3
Fuchs, H.4
Paton, V.5
Bajamonde, A.6
-
16
-
-
0037172982
-
Conditional mutation of the ErbB2 (HER2) receptor in cardiomyocytes leads to dilated cardiomyopathy
-
Ozcelik C., Erdmann B., Pilz B., Wettschureck N., Britsch S., Hubner N., et al. Conditional mutation of the ErbB2 (HER2) receptor in cardiomyocytes leads to dilated cardiomyopathy. Proc Natl Acad Sci USA 2002, 99(13):8880-8885.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, Issue.13
, pp. 8880-8885
-
-
Ozcelik, C.1
Erdmann, B.2
Pilz, B.3
Wettschureck, N.4
Britsch, S.5
Hubner, N.6
-
17
-
-
0036099675
-
ErbB2 is essential in the prevention of dilated cardiomyopathy
-
Crone S.A., Zhao Y.Y., Fan L., Gu Y., Minamisawa S., Liu Y., et al. ErbB2 is essential in the prevention of dilated cardiomyopathy. Nat Med 2002, 8(5):459-465.
-
(2002)
Nat Med
, vol.8
, Issue.5
, pp. 459-465
-
-
Crone, S.A.1
Zhao, Y.Y.2
Fan, L.3
Gu, Y.4
Minamisawa, S.5
Liu, Y.6
-
18
-
-
22544475191
-
Heterozygous knockout of neuregulin-1 gene in mice exacerbates doxorubicin-induced heart failure
-
Liu F.F., Stone J.R., Schuldt A.J., Okoshi K., Okoshi M.P., Nakayama M., et al. Heterozygous knockout of neuregulin-1 gene in mice exacerbates doxorubicin-induced heart failure. Am J Physiol Heart Circ Physiol 2005, 289(2):H660-H666.
-
(2005)
Am J Physiol Heart Circ Physiol
, vol.289
, Issue.2
-
-
Liu, F.F.1
Stone, J.R.2
Schuldt, A.J.3
Okoshi, K.4
Okoshi, M.P.5
Nakayama, M.6
-
19
-
-
0037007076
-
Modulation of anthracycline-induced myofibrillar disarray in rat ventricular myocytes by neuregulin-1beta and anti-erbB2: potential mechanism for trastuzumab-induced cardiotoxicity
-
Sawyer D.B., Zuppinger C., Miller T.A., Eppenberger H.M., Suter T.M. Modulation of anthracycline-induced myofibrillar disarray in rat ventricular myocytes by neuregulin-1beta and anti-erbB2: potential mechanism for trastuzumab-induced cardiotoxicity. Circulation 2002, 105(13):1551-1554.
-
(2002)
Circulation
, vol.105
, Issue.13
, pp. 1551-1554
-
-
Sawyer, D.B.1
Zuppinger, C.2
Miller, T.A.3
Eppenberger, H.M.4
Suter, T.M.5
-
20
-
-
67650133506
-
Serum Neuregulin-1? as a Biomarker of Cardiovascular Fitness
-
Moondra V., Sarma S., Buxton T., Safa R., Cote G., Storer T., et al. Serum Neuregulin-1? as a Biomarker of Cardiovascular Fitness. Open Biomark J 2009, 2:5.
-
(2009)
Open Biomark J
, vol.2
, pp. 5
-
-
Moondra, V.1
Sarma, S.2
Buxton, T.3
Safa, R.4
Cote, G.5
Storer, T.6
-
21
-
-
0037405153
-
Regulation of neuregulin/ErbB signaling by contractile activity in skeletal muscle
-
Lebrasseur N.K., Cote G.M., Miller T.A., Fielding R.A., Sawyer D.B. Regulation of neuregulin/ErbB signaling by contractile activity in skeletal muscle. Am J Physiol Cell Physiol 2003, 284(5):C1149-C1155.
-
(2003)
Am J Physiol Cell Physiol
, vol.284
, Issue.5
-
-
Lebrasseur, N.K.1
Cote, G.M.2
Miller, T.A.3
Fielding, R.A.4
Sawyer, D.B.5
-
22
-
-
68249087127
-
Neuregulin-1 beta is associated with disease severity and adverse outcomes in chronic heart failure
-
Ky B., Kimmel S.E., Safa R.N., Putt M.E., Sweitzer N.K., Fang J.C., et al. Neuregulin-1 beta is associated with disease severity and adverse outcomes in chronic heart failure. Circulation 2009, 120(4):310-317.
-
(2009)
Circulation
, vol.120
, Issue.4
, pp. 310-317
-
-
Ky, B.1
Kimmel, S.E.2
Safa, R.N.3
Putt, M.E.4
Sweitzer, N.K.5
Fang, J.C.6
-
23
-
-
10944236872
-
Cardiac endothelial cells regulate reactive oxygen species-induced cardiomyocyte apoptosis through neuregulin-1beta/erbB4 signaling
-
Kuramochi Y., Cote G.M., Guo X., Lebrasseur N.K., Cui L., Liao R., et al. Cardiac endothelial cells regulate reactive oxygen species-induced cardiomyocyte apoptosis through neuregulin-1beta/erbB4 signaling. J Biol Chem 2004, 279(49):51141-51147.
-
(2004)
J Biol Chem
, vol.279
, Issue.49
, pp. 51141-51147
-
-
Kuramochi, Y.1
Cote, G.M.2
Guo, X.3
Lebrasseur, N.K.4
Cui, L.5
Liao, R.6
-
24
-
-
34548132413
-
Role of neuregulin-1/ErbB signaling in cardiovascular physiology and disease: implications for therapy of heart failure
-
Lemmens K., Doggen K., De Keulenaer G.W. Role of neuregulin-1/ErbB signaling in cardiovascular physiology and disease: implications for therapy of heart failure. Circulation 2007, 116(8):954-960.
-
(2007)
Circulation
, vol.116
, Issue.8
, pp. 954-960
-
-
Lemmens, K.1
Doggen, K.2
De Keulenaer, G.W.3
-
25
-
-
57149098209
-
Ventricular ErbB2/ErbB4 activation and downstream signaling in pacing-induced heart failure
-
Doggen K., Ray L., Mathieu M., Mc Entee K., Lemmens K., De Keulenaer G.W. Ventricular ErbB2/ErbB4 activation and downstream signaling in pacing-induced heart failure. J Mol Cell Cardiol 2009, 46(1):33-38.
-
(2009)
J Mol Cell Cardiol
, vol.46
, Issue.1
, pp. 33-38
-
-
Doggen, K.1
Ray, L.2
Mathieu, M.3
Mc Entee, K.4
Lemmens, K.5
De Keulenaer, G.W.6
-
26
-
-
0033609458
-
Neuregulin in cardiac hypertrophy in rats with aortic stenosis. Differential expression of erbB2 and erbB4 receptors
-
Rohrbach S., Yan X., Weinberg E.O., Hasan F., Bartunek J., Marchionni M.A., et al. Neuregulin in cardiac hypertrophy in rats with aortic stenosis. Differential expression of erbB2 and erbB4 receptors. Circulation 1999, 100(4):407-412.
-
(1999)
Circulation
, vol.100
, Issue.4
, pp. 407-412
-
-
Rohrbach, S.1
Yan, X.2
Weinberg, E.O.3
Hasan, F.4
Bartunek, J.5
Marchionni, M.A.6
-
27
-
-
25144465666
-
Neuregulin receptors erbB2 and erbB4 in failing human myocardium - depressed expression and attenuated activation
-
Rohrbach S., Niemann B., Silber R.E., Holtz J. Neuregulin receptors erbB2 and erbB4 in failing human myocardium - depressed expression and attenuated activation. Basic Res Cardiol 2005, 100(3):240-249.
-
(2005)
Basic Res Cardiol
, vol.100
, Issue.3
, pp. 240-249
-
-
Rohrbach, S.1
Niemann, B.2
Silber, R.E.3
Holtz, J.4
-
28
-
-
70149110196
-
Preventive effects of heregulin-beta1 on macrophage foam cell formation and atherosclerosis
-
Xu G., Watanabe T., Iso Y., Koba S., Sakai T., Nagashima M., et al. Preventive effects of heregulin-beta1 on macrophage foam cell formation and atherosclerosis. Circ Res 2009, 105(5):500-510.
-
(2009)
Circ Res
, vol.105
, Issue.5
, pp. 500-510
-
-
Xu, G.1
Watanabe, T.2
Iso, Y.3
Koba, S.4
Sakai, T.5
Nagashima, M.6
-
29
-
-
34548055891
-
Neuregulin-1 genotype moderates the association between job strain and early atherosclerosis in young men
-
Hintsanen M., Elovainio M., Puttonen S., Kivimaki M., Raitakari O.T., Lehtimaki T., et al. Neuregulin-1 genotype moderates the association between job strain and early atherosclerosis in young men. Ann Behav Med 2007, 33(2):148-155.
-
(2007)
Ann Behav Med
, vol.33
, Issue.2
, pp. 148-155
-
-
Hintsanen, M.1
Elovainio, M.2
Puttonen, S.3
Kivimaki, M.4
Raitakari, O.T.5
Lehtimaki, T.6
-
30
-
-
33748929841
-
Neuregulin-1/erbB-activation improves cardiac function and survival in models of ischemic, dilated, and viral cardiomyopathy
-
Liu X., Gu X., Li Z., Li X., Li H., Chang J., et al. Neuregulin-1/erbB-activation improves cardiac function and survival in models of ischemic, dilated, and viral cardiomyopathy. J Am Coll Cardiol 2006, 48(7):1438-1447.
-
(2006)
J Am Coll Cardiol
, vol.48
, Issue.7
, pp. 1438-1447
-
-
Liu, X.1
Gu, X.2
Li, Z.3
Li, X.4
Li, H.5
Chang, J.6
-
31
-
-
72249094133
-
Neuregulin-1 attenuated doxorubicin-induced decrease in cardiac troponins
-
Bian Y., Sun M., Silver M., Ho K.K., Marchionni M.A., Caggiano A.O., et al. Neuregulin-1 attenuated doxorubicin-induced decrease in cardiac troponins. Am J Physiol Heart Circ Physiol 2009, 297(6):H1974-H1983.
-
(2009)
Am J Physiol Heart Circ Physiol
, vol.297
, Issue.6
-
-
Bian, Y.1
Sun, M.2
Silver, M.3
Ho, K.K.4
Marchionni, M.A.5
Caggiano, A.O.6
-
32
-
-
33846588522
-
Effects of recombined human neuregulin on the contractibility of cardiac muscles of rhesus monkeys with pacing-induced heart failure
-
Li J., Gu X.H., Duan J.C., Zeng L., Li Y., Wang L. Effects of recombined human neuregulin on the contractibility of cardiac muscles of rhesus monkeys with pacing-induced heart failure. Sichuan Da Xue Xue Bao Yi Xue Ban 2007, 38(1):105-108.
-
(2007)
Sichuan Da Xue Xue Bao Yi Xue Ban
, vol.38
, Issue.1
, pp. 105-108
-
-
Li, J.1
Gu, X.H.2
Duan, J.C.3
Zeng, L.4
Li, Y.5
Wang, L.6
-
33
-
-
67650569135
-
Neuregulin1/ErbB4 signaling induces cardiomyocyte proliferation and repair of heart injury
-
Bersell K., Arab S., Haring B., Kuhn B. Neuregulin1/ErbB4 signaling induces cardiomyocyte proliferation and repair of heart injury. Cell 2009, 138(2):257-270.
-
(2009)
Cell
, vol.138
, Issue.2
, pp. 257-270
-
-
Bersell, K.1
Arab, S.2
Haring, B.3
Kuhn, B.4
-
34
-
-
80052820484
-
Neuregulin Treatment of Heart Failure in Rat
-
[2008; 103: e51]
-
Ganguly A., iaci J.F., Srinivas M., Vecchione A.V., Hackett C.S., Kasperbauer S., et al. Neuregulin Treatment of Heart Failure in Rat. Circ Res 2008, 103:e51. [2008; 103: e51].
-
(2008)
Circ Res
, vol.103
-
-
Ganguly, A.1
iaci, J.F.2
Srinivas, M.3
Vecchione, A.V.4
Hackett, C.S.5
Kasperbauer, S.6
-
35
-
-
0030009007
-
Neuregulins with an Ig-like domain are essential for mouse myocardial and neuronal development
-
Kramer R., Bucay N., Kane D.J., Martin L.E., Tarpley J.E., Theill L.E. Neuregulins with an Ig-like domain are essential for mouse myocardial and neuronal development. Proc Natl Acad Sci USA 1996, 93(10):4833-4838.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, Issue.10
, pp. 4833-4838
-
-
Kramer, R.1
Bucay, N.2
Kane, D.J.3
Martin, L.E.4
Tarpley, J.E.5
Theill, L.E.6
-
36
-
-
33749353121
-
The immunoglobulin-like domain is involved in interaction of Neuregulin1 with ErbB
-
Eto K., Eda K., Kanemoto S., Abe S. The immunoglobulin-like domain is involved in interaction of Neuregulin1 with ErbB. Biochem Biophys Res Commun 2006, 350(2):263-271.
-
(2006)
Biochem Biophys Res Commun
, vol.350
, Issue.2
, pp. 263-271
-
-
Eto, K.1
Eda, K.2
Kanemoto, S.3
Abe, S.4
-
37
-
-
1642458136
-
Neuregulin-1 induces a negative inotropic effect in cardiac muscle: role of nitric oxide synthase
-
Lemmens K., Fransen P., Sys S.U., Brutsaert D.L., De Keulenaer G.W. Neuregulin-1 induces a negative inotropic effect in cardiac muscle: role of nitric oxide synthase. Circulation 2004, 109(3):324-326.
-
(2004)
Circulation
, vol.109
, Issue.3
, pp. 324-326
-
-
Lemmens, K.1
Fransen, P.2
Sys, S.U.3
Brutsaert, D.L.4
De Keulenaer, G.W.5
-
38
-
-
4043110498
-
Neuregulins regulate cardiac parasympathetic activity: muscarinic modulation of beta-adrenergic activity in myocytes from mice with neuregulin-1 gene deletion
-
Okoshi K., Nakayama M., Yan X., Okoshi M.P., Schuldt A.J., Marchionni M.A., et al. Neuregulins regulate cardiac parasympathetic activity: muscarinic modulation of beta-adrenergic activity in myocytes from mice with neuregulin-1 gene deletion. Circulation 2004, 110(6):713-717.
-
(2004)
Circulation
, vol.110
, Issue.6
, pp. 713-717
-
-
Okoshi, K.1
Nakayama, M.2
Yan, X.3
Okoshi, M.P.4
Schuldt, A.J.5
Marchionni, M.A.6
-
39
-
-
33750347979
-
Neuregulin-1 beta attenuates doxorubicin-induced alterations of excitation-contraction coupling and reduces oxidative stress in adult rat cardiomyocytes
-
Timolati F., Ott D., Pentassuglia L., Giraud M.N., Perriard J.C., Suter T.M., et al. Neuregulin-1 beta attenuates doxorubicin-induced alterations of excitation-contraction coupling and reduces oxidative stress in adult rat cardiomyocytes. J Mol Cell Cardiol 2006, 41(5):845-854.
-
(2006)
J Mol Cell Cardiol
, vol.41
, Issue.5
, pp. 845-854
-
-
Timolati, F.1
Ott, D.2
Pentassuglia, L.3
Giraud, M.N.4
Perriard, J.C.5
Suter, T.M.6
-
40
-
-
78149338262
-
Neuregulin-1beta1 rapidly modulates nitric oxide synthesis and calcium handling in rat cardiomyocytes
-
Brero A., Ramella R., Fitou A., Dati C., Alloatti G., Gallo M.P., et al. Neuregulin-1beta1 rapidly modulates nitric oxide synthesis and calcium handling in rat cardiomyocytes. Cardiovasc Res 2010, 88(3):443-452.
-
(2010)
Cardiovasc Res
, vol.88
, Issue.3
, pp. 443-452
-
-
Brero, A.1
Ramella, R.2
Fitou, A.3
Dati, C.4
Alloatti, G.5
Gallo, M.P.6
-
41
-
-
77952317892
-
A Phase II, randomized, double-blind, multicenter, based on standard therapy, placebo-controlled study of the efficacy and safety of recombinant human neuregulin-1 in patients with chronic heart failure
-
Gao R., Zhang J., Cheng L., Wu X., Dong W., Yang X., et al. A Phase II, randomized, double-blind, multicenter, based on standard therapy, placebo-controlled study of the efficacy and safety of recombinant human neuregulin-1 in patients with chronic heart failure. J Am Coll Cardiol 2010, 55(18):1907-1914.
-
(2010)
J Am Coll Cardiol
, vol.55
, Issue.18
, pp. 1907-1914
-
-
Gao, R.1
Zhang, J.2
Cheng, L.3
Wu, X.4
Dong, W.5
Yang, X.6
-
42
-
-
78650412123
-
Parenteral administration of recombinant human neuregulin-1 to patients with stable chronic heart failure produces favourable acute and chronic haemodynamic responses
-
Jabbour A., Hayward C.S., Keogh A.M., Kotlyar E., McCrohon J.A., England J.F., et al. Parenteral administration of recombinant human neuregulin-1 to patients with stable chronic heart failure produces favourable acute and chronic haemodynamic responses. Eur J Heart Fail 2011, 13(1):83-92.
-
(2011)
Eur J Heart Fail
, vol.13
, Issue.1
, pp. 83-92
-
-
Jabbour, A.1
Hayward, C.S.2
Keogh, A.M.3
Kotlyar, E.4
McCrohon, J.A.5
England, J.F.6
-
43
-
-
80052791284
-
Clinical Trial to Evaluate the Efficacy and Safety of Recombinant Human Neuregulin-1 for Subcutaneous Administration in Patients With Chronic Systolic Heart Failure
-
Zensun Sci. and Tech.Co.L.
-
Zensun Sci., &, Tech.Co.L. Clinical Trial to Evaluate the Efficacy and Safety of Recombinant Human Neuregulin-1 for Subcutaneous Administration in Patients With Chronic Systolic Heart Failure. Clinical Trials Gov 2010.
-
(2010)
Clinical Trials Gov
-
-
-
44
-
-
80052797620
-
Study of the Survival of Recombinant Human Neuregulin-1? in Chronic Heart Failure (CHF) Patients
-
Zensun Sci. and Tech.Co.L.
-
Zensun Sci., &, Tech.Co.L. Study of the Survival of Recombinant Human Neuregulin-1? in Chronic Heart Failure (CHF) Patients. Clinical Trials Gov 2010.
-
(2010)
Clinical Trials Gov
-
-
-
45
-
-
80052795917
-
Efficacy and Safety of Human Neuregulin-1 to Treat Stable Chronic Heart Failure (ZS-01-210)
-
Zensun Sci. and Tech.Co.L.
-
Zensun Sci., &, Tech.Co.L. Efficacy and Safety of Human Neuregulin-1 to Treat Stable Chronic Heart Failure (ZS-01-210). Clinical Trials Gov 2010.
-
(2010)
Clinical Trials Gov
-
-
-
46
-
-
80052819478
-
Single Ascending Doses of GGF2 in Patients With Left Ventricular Dysfunction and Symptomatic Heart Failure (GGF2-1101-1)
-
Therapeutics A. Single Ascending Doses of GGF2 in Patients With Left Ventricular Dysfunction and Symptomatic Heart Failure (GGF2-1101-1). Clinical Trials Gov 2010.
-
(2010)
Clinical Trials Gov
-
-
Therapeutics, A.1
-
47
-
-
0035256698
-
Untangling the ErbB signalling network
-
Yarden Y., Sliwkowski M.X. Untangling the ErbB signalling network. Nat Rev Mol Cell Biol 2001, 2(2):127-137.
-
(2001)
Nat Rev Mol Cell Biol
, vol.2
, Issue.2
, pp. 127-137
-
-
Yarden, Y.1
Sliwkowski, M.X.2
-
48
-
-
70450236961
-
The NRG1 gene is frequently silenced by methylation in breast cancers and is a strong candidate for the 8p tumour suppressor gene
-
Chua Y.L., Ito Y., Pole J.C., Newman S., Chin S.F., Stein R.C., et al. The NRG1 gene is frequently silenced by methylation in breast cancers and is a strong candidate for the 8p tumour suppressor gene. Oncogene 2009, 28(46):4041-4052.
-
(2009)
Oncogene
, vol.28
, Issue.46
, pp. 4041-4052
-
-
Chua, Y.L.1
Ito, Y.2
Pole, J.C.3
Newman, S.4
Chin, S.F.5
Stein, R.C.6
-
49
-
-
0037226817
-
Heregulin is sufficient for the promotion of tumorigenicity and metastasis of breast cancer cells in vivo
-
Atlas E., Cardillo M., Mehmi I., Zahedkargaran H., Tang C., Lupu R. Heregulin is sufficient for the promotion of tumorigenicity and metastasis of breast cancer cells in vivo. Mol Cancer Res 2003, 1(3):165-175.
-
(2003)
Mol Cancer Res
, vol.1
, Issue.3
, pp. 165-175
-
-
Atlas, E.1
Cardillo, M.2
Mehmi, I.3
Zahedkargaran, H.4
Tang, C.5
Lupu, R.6
-
50
-
-
78650083166
-
Phenotypic characterization of transgenic mice overexpressing neuregulin-1
-
Kato T., Kasai A., Mizuno M., Fengyi L., Shintani N., Maeda S., et al. Phenotypic characterization of transgenic mice overexpressing neuregulin-1. PLoS One 2010, 5(12):e14185.
-
(2010)
PLoS One
, vol.5
, Issue.12
-
-
Kato, T.1
Kasai, A.2
Mizuno, M.3
Fengyi, L.4
Shintani, N.5
Maeda, S.6
-
51
-
-
0034466119
-
Neuregulin in neuron/glial interactions in the central nervous system. GGF2 diminishes autoimmune demyelination, promotes oligodendrocyte progenitor expansion, and enhances remyelination
-
Marchionni M.A., Cannella B., Hoban C., Gao Y.L., Garcia-Arenas R., Lawson D., et al. Neuregulin in neuron/glial interactions in the central nervous system. GGF2 diminishes autoimmune demyelination, promotes oligodendrocyte progenitor expansion, and enhances remyelination. Adv Exp Med Biol 1999, 468:283-295.
-
(1999)
Adv Exp Med Biol
, vol.468
, pp. 283-295
-
-
Marchionni, M.A.1
Cannella, B.2
Hoban, C.3
Gao, Y.L.4
Garcia-Arenas, R.5
Lawson, D.6
-
52
-
-
6044220229
-
Neuregulin-1 is neuroprotective and attenuates inflammatory responses induced by ischemic stroke
-
Xu Z., Jiang J., Ford G., Ford B.D. Neuregulin-1 is neuroprotective and attenuates inflammatory responses induced by ischemic stroke. Biochem Biophys Res Commun 2004, 322(2):440-446.
-
(2004)
Biochem Biophys Res Commun
, vol.322
, Issue.2
, pp. 440-446
-
-
Xu, Z.1
Jiang, J.2
Ford, G.3
Ford, B.D.4
-
53
-
-
77958082505
-
Glial growth factor 2 promotes functional recovery with treatment initiated up to 7days after permanent focal ischemic stroke
-
Iaci J.F., Ganguly A., Finklestein S.P., Parry T.J., Ren J., Saha S., et al. Glial growth factor 2 promotes functional recovery with treatment initiated up to 7days after permanent focal ischemic stroke. Neuropharmacology 2010, 59(7-8):640-649.
-
(2010)
Neuropharmacology
, vol.59
, Issue.7-8
, pp. 640-649
-
-
Iaci, J.F.1
Ganguly, A.2
Finklestein, S.P.3
Parry, T.J.4
Ren, J.5
Saha, S.6
-
54
-
-
0013375948
-
Neuregulin 1 and susceptibility to schizophrenia
-
Stefansson H., Sigurdsson E., Steinthorsdottir V., Bjornsdottir S., Sigmundsson T., Ghosh S., et al. Neuregulin 1 and susceptibility to schizophrenia. Am J Hum Genet 2002, 71(4):877-892.
-
(2002)
Am J Hum Genet
, vol.71
, Issue.4
, pp. 877-892
-
-
Stefansson, H.1
Sigurdsson, E.2
Steinthorsdottir, V.3
Bjornsdottir, S.4
Sigmundsson, T.5
Ghosh, S.6
-
55
-
-
0002820468
-
The glial growth factors deficiency and synaptic destabilization hypothesis of schizophrenia
-
Moises H.W., Zoega T., Gottesman I.I. The glial growth factors deficiency and synaptic destabilization hypothesis of schizophrenia. BMC Psychiatry 2002, 2:8.
-
(2002)
BMC Psychiatry
, vol.2
, pp. 8
-
-
Moises, H.W.1
Zoega, T.2
Gottesman, I.I.3
-
56
-
-
1842629561
-
Synergistic improvements in cell and axonal migration across sciatic nerve lesion gaps using bioresorbable filaments and heregulin-beta1
-
Cai J., Peng X., Nelson K.D., Eberhart R., Smith G.M. Synergistic improvements in cell and axonal migration across sciatic nerve lesion gaps using bioresorbable filaments and heregulin-beta1. J Biomed Mater Res A 2004, 69(2):247-258.
-
(2004)
J Biomed Mater Res A
, vol.69
, Issue.2
, pp. 247-258
-
-
Cai, J.1
Peng, X.2
Nelson, K.D.3
Eberhart, R.4
Smith, G.M.5
-
57
-
-
0034655960
-
RhGGF2 protects against cisplatin-induced neuropathy in the rat
-
ter Laak M.P., Hamers F.P., Kirk C.J., Gispen W.H. rhGGF2 protects against cisplatin-induced neuropathy in the rat. J Neurosci Res 2000, 60(2):237-244.
-
(2000)
J Neurosci Res
, vol.60
, Issue.2
, pp. 237-244
-
-
ter Laak, M.P.1
Hamers, F.P.2
Kirk, C.J.3
Gispen, W.H.4
-
58
-
-
0028895952
-
Neuregulins are concentrated at nerve-muscle synapses and activate ACh- receptor gene expression
-
Jo S.A., Zhu X., Marchionni M.A., Burden S.J. Neuregulins are concentrated at nerve-muscle synapses and activate ACh- receptor gene expression. Nature 1995, 373(6510):158-161.
-
(1995)
Nature
, vol.373
, Issue.6510
, pp. 158-161
-
-
Jo, S.A.1
Zhu, X.2
Marchionni, M.A.3
Burden, S.J.4
-
59
-
-
0038054255
-
Differentiation-dependent regulation of skeletal myogenesis by neuregulin-1
-
Ford B.D., Han B., Fischbach G.D. Differentiation-dependent regulation of skeletal myogenesis by neuregulin-1. Biochem Biophys Res Commun 2003, 306(1):276-281.
-
(2003)
Biochem Biophys Res Commun
, vol.306
, Issue.1
, pp. 276-281
-
-
Ford, B.D.1
Han, B.2
Fischbach, G.D.3
-
60
-
-
0035947614
-
A novel role of neuregulin in skeletal muscle. Neuregulin stimulates glucose uptake, glucose transporter translocation, and transporter expression in muscle cells
-
Suarez E., Bach D., Cadefau J., Palacin M., Zorzano A., Guma A. A novel role of neuregulin in skeletal muscle. Neuregulin stimulates glucose uptake, glucose transporter translocation, and transporter expression in muscle cells. J Biol Chem 2001, 276(21):18257-18264.
-
(2001)
J Biol Chem
, vol.276
, Issue.21
, pp. 18257-18264
-
-
Suarez, E.1
Bach, D.2
Cadefau, J.3
Palacin, M.4
Zorzano, A.5
Guma, A.6
-
61
-
-
0029886737
-
Stimulation of myogenic differentiation by a neuregulin, glial growth factor 2. Are neuregulins the long-sought muscle trophic factors secreted by nerves?
-
Florini J.R., Samuel D.S., Ewton D.Z., Kirk C., Sklar R.M. Stimulation of myogenic differentiation by a neuregulin, glial growth factor 2. Are neuregulins the long-sought muscle trophic factors secreted by nerves?. J Biol Chem 1996, 271(22):12699-12702.
-
(1996)
J Biol Chem
, vol.271
, Issue.22
, pp. 12699-12702
-
-
Florini, J.R.1
Samuel, D.S.2
Ewton, D.Z.3
Kirk, C.4
Sklar, R.M.5
-
62
-
-
0037290636
-
Intracellular signals involved in the effects of insulin-like growth factors and neuregulins on myofibre formation
-
Zorzano A., Kaliman P., Guma A., Palacin M. Intracellular signals involved in the effects of insulin-like growth factors and neuregulins on myofibre formation. Cell Signal 2003, 15(2):141-149.
-
(2003)
Cell Signal
, vol.15
, Issue.2
, pp. 141-149
-
-
Zorzano, A.1
Kaliman, P.2
Guma, A.3
Palacin, M.4
-
63
-
-
0344924865
-
Neuregulin-1 protects ventricular myocytes from anthracycline-induced apoptosis via erbB4-dependent activation of PI3-kinase/Akt
-
Fukazawa R., Miller T.A., Kuramochi Y., Frantz S., Kim Y.D., Marchionni M.A., et al. Neuregulin-1 protects ventricular myocytes from anthracycline-induced apoptosis via erbB4-dependent activation of PI3-kinase/Akt. J Mol Cell Cardiol 2003, 35(12):1473-1479.
-
(2003)
J Mol Cell Cardiol
, vol.35
, Issue.12
, pp. 1473-1479
-
-
Fukazawa, R.1
Miller, T.A.2
Kuramochi, Y.3
Frantz, S.4
Kim, Y.D.5
Marchionni, M.A.6
-
64
-
-
9644310269
-
Inhibition of ErbB2 causes mitochondrial dysfunction in cardiomyocytes: implications for herceptin-induced cardiomyopathy
-
Grazette L.P., Boecker W., Matsui T., Semigran M., Force T.L., Hajjar R.J., et al. Inhibition of ErbB2 causes mitochondrial dysfunction in cardiomyocytes: implications for herceptin-induced cardiomyopathy. J Am Coll Cardiol 2004, 44(11):2231-2238.
-
(2004)
J Am Coll Cardiol
, vol.44
, Issue.11
, pp. 2231-2238
-
-
Grazette, L.P.1
Boecker, W.2
Matsui, T.3
Semigran, M.4
Force, T.L.5
Hajjar, R.J.6
-
65
-
-
0032714208
-
NRG-1-induced cardiomyocyte hypertrophy. Role of PI-3-kinase, p70(S6K), and MEK-MAPK-RSK
-
Baliga R.R., Pimental D.R., Zhao Y.Y., Simmons W.W., Marchionni M.A., Sawyer D.B., et al. NRG-1-induced cardiomyocyte hypertrophy. Role of PI-3-kinase, p70(S6K), and MEK-MAPK-RSK. Am J Physiol Heart Circ Physiol 1999, 277(5 Pt 2):H2026-H37.
-
(1999)
Am J Physiol Heart Circ Physiol
, vol.277
, Issue.5 PART 2
-
-
Baliga, R.R.1
Pimental, D.R.2
Zhao, Y.Y.3
Simmons, W.W.4
Marchionni, M.A.5
Sawyer, D.B.6
-
66
-
-
33746048823
-
Neuregulin activates erbB2-dependent src/FAK signaling and cytoskeletal remodeling in isolated adult rat cardiac myocytes
-
Kuramochi Y., Guo X., Sawyer D.B. Neuregulin activates erbB2-dependent src/FAK signaling and cytoskeletal remodeling in isolated adult rat cardiac myocytes. J Mol Cell Cardiol 2006, 41(2):228-235.
-
(2006)
J Mol Cell Cardiol
, vol.41
, Issue.2
, pp. 228-235
-
-
Kuramochi, Y.1
Guo, X.2
Sawyer, D.B.3
-
67
-
-
77957270888
-
Neuregulin/ErbB signaling regulates cardiac subtype specification in differentiating human embryonic stem cells
-
Zhu W.Z., Xie Y., Moyes K.W., Gold J.D., Askari B., Laflamme M.A. Neuregulin/ErbB signaling regulates cardiac subtype specification in differentiating human embryonic stem cells. Circ Res 2010, 107(6):776-786.
-
(2010)
Circ Res
, vol.107
, Issue.6
, pp. 776-786
-
-
Zhu, W.Z.1
Xie, Y.2
Moyes, K.W.3
Gold, J.D.4
Askari, B.5
Laflamme, M.A.6
-
68
-
-
0036677402
-
Neuregulin-1 promotes formation of the murine cardiac conduction system
-
Rentschler S., Zander J., Meyers K., France D., Levine R., Porter G., et al. Neuregulin-1 promotes formation of the murine cardiac conduction system. Proc Natl Acad Sci USA 2002, 99(16):10464-10469.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, Issue.16
, pp. 10464-10469
-
-
Rentschler, S.1
Zander, J.2
Meyers, K.3
France, D.4
Levine, R.5
Porter, G.6
-
69
-
-
79955072413
-
Neuregulin-1{beta} Regulation of Embryonic Endothelial Progenitor Cell Survival
-
Safa R., Peng X.Y., Pentassuglia L., Lim C.C., Lamparter M., Silverstein C., et al. Neuregulin-1{beta} Regulation of Embryonic Endothelial Progenitor Cell Survival. Am J Physiol Heart Circ Physiol 2011, 300(46):H1311-H1319.
-
(2011)
Am J Physiol Heart Circ Physiol
, vol.300
, Issue.46
-
-
Safa, R.1
Peng, X.Y.2
Pentassuglia, L.3
Lim, C.C.4
Lamparter, M.5
Silverstein, C.6
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