The acute coagulopathy of trauma is due to impaired initial thrombin generation but not clot formation or clot strength

Journal of Surgical Research

Volumn 170, Issue 2, 2011, Pages 319-324

  Harr, Jeffrey N ^a   Moore, Ernest E ^a,b   Wohlauer, Max V ^a   Droz, Nathan ^c   Fragoso, Miguel ^b   Banerjee, Anirban ^b   Silliman, Christopher C ^d,e  

^a UNIVERSITY OF COLORADO   (United States)

^b DENVER HEALTH MEDICAL CENTER   (United States)

^c CREIGHTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d Children's Hospital Colorado   (United States)

^e Bonfils Blood Center   (United States)

Author keywords

acute coagulopathy of trauma; disseminated intravascular coagulation (DIC); hemorrhagic shock; protein C; thrombelastography (TEG); thrombin generation; trauma

Indexed keywords

THROMBIN;

ACUTE COAGULOPATHY OF TRAUMA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLEEDING; BLOOD CLOTTING; BLOOD CLOTTING DISORDER; BLOOD VOLUME; DISEASE MODEL; FIBRINOLYSIS; HEMORRHAGIC SHOCK; INJURY; LAPAROTOMY; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; PRIORITY JOURNAL; RAT; RESUSCITATION; THROMBOELASTOGRAPHY;

ACUTE DISEASE; ANIMALS; BLOOD COAGULATION; DISEASE MODELS, ANIMAL; DISSEMINATED INTRAVASCULAR COAGULATION; FIBRINOLYSIS; MALE; RATS; RATS, SPRAGUE-DAWLEY; SHOCK, HEMORRHAGIC; THROMBELASTOGRAPHY; THROMBIN; WOUNDS AND INJURIES;

EID: 80052789424     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2011.03.047     Document Type: Article

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