Changes to surgical and hospitalization rates of pediatric inflammatory bowel disease in Ontario, Canada (1994-2007)

Inflammatory Bowel Diseases

Volumn 17, Issue 10, 2011, Pages 2153-2161

  Benchimol, Eric I ^a,b,c   Guttmann, Astrid ^a,c,d   To, Teresa ^a,c   Rabeneck, Linda ^a,c,e,f   Griffiths, Anne M ^b,c  

^a INSTITUTE FOR CLINICAL EVALUATIVE SCIENCES   (Canada)

^b CHILDREN S HOSPITAL OF EASTERN ONTARIO   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

^d HOSPITAL FOR SICK CHILDREN   (Canada)

^e UNIVERSITY OF TORONTO   (Canada)

^f SUNNYBROOK RESEARCH INSTITUTE   (Canada)

Author keywords

health administrative data; health services research; hospitalization rates; inflammatory bowel disease; pediatrics; surgical rates

Indexed keywords

IMMUNOMODULATING AGENT;

ABDOMINAL SURGERY; ADOLESCENT; ARTICLE; CANADA; CHILD; CHILDHOOD DISEASE; CROHN DISEASE; DRUG USE; ENTERITIS; FEMALE; FOLLOW UP; HEALTH CARE UTILIZATION; HEALTH SERVICE; HOSPITALIZATION; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SCHOOL CHILD; ULCERATIVE COLITIS;

ADOLESCENT; AMBULATORY CARE; CHILD; CHILD, PRESCHOOL; COHORT STUDIES; COLITIS, ULCERATIVE; CROHN DISEASE; FEMALE; FOLLOW-UP STUDIES; HOSPITALIZATION; HUMANS; IMMUNOMODULATION; INFANT; MALE; ONTARIO; SURVIVAL RATE; TREATMENT OUTCOME;

EID: 80052780493     PISSN: 10780998     EISSN: 15364844     Source Type: Journal    
DOI: 10.1002/ibd.21591     Document Type: Article

References (27)

1. Kelsen J, Baldassano RN,. Inflammatory bowel disease: the difference between children and adults. Inflamm Bowel Dis. 2008; 14: S9-S11.
2. Wang C, Guttmann A, To T, et al. Neighborhood income and health outcomes in infants: how do those with complex chronic conditions fare? Arch Pediatr Adolesc Med. 2009; 163: 608-615.
3. Markowitz J, Grancher K, Mandel F, et al. Immunosuppressive therapy in pediatric inflammatory bowel disease: results of a survey of the North American Society for Pediatric Gastroenterology and Nutrition. Subcommittee on Immunosuppressive Use of the Pediatric IBD Collaborative Research Forum. Am J Gastroenterol. 1993; 88: 44-48.
4. Markowitz J, Grancher K, Kohn N, et al. A multicenter trial of 6-mercaptopurine and prednisone in children with newly diagnosed Crohn's disease. Gastroenterology. 2000; 119: 895-902.
5. Hyams J, Crandall W, Kugathasan S, et al. Induction and maintenance infliximab therapy for the treatment of moderate-to-severe Crohn's disease in children. Gastroenterology. 2007; 132: 863-873; quiz 1165-1166.
6. Dryden GW Jr,. Overview of biologic therapy for Crohn's disease. Expert Opin Biol Ther. 2009; 9: 967-974.
7. Benchimol EI, Guttmann A, Griffiths AM, et al. Increasing incidence of paediatric inflammatory bowel disease in Ontario, Canada: evidence from health administrative data. Gut. 2009; 58: 1490-1497.
8. Data Quality of the Discharge Abstract Database Following the First-Year Implementation of ICD-10-CA/CCI. 2004. Available at: Accessed October 8, 2009.
9. Ontario Drug Benefit Program - Ministry Programs - Public Information. 2010. Available at: Accessed Sept 8, 2010.
10. Statistics Canada. Population and Dwelling Counts, for Canada, Provinces, Territories and Census Subdivisions (Municipalities), 2006 Census, 100% Data (table). Population and Dwelling Counts. 2007. Available at: Accessed 16 April, 2009.
11. Wilkins R,. PCCF+ Version 4E User's Guide: Automated Geographic Coding Based on the Statistics Canada Postal Code Convesion Files, Including Postal Codes to July 2004. Ottawa, Canada: Health Analysis and Measurement Group, Statistics Canada. Catalogue No. 93-387-XIE; 2005.
12. Greenland S,. Invited commentary: variable selection versus shrinkage in the control of multiple confounders. Am J Epidemiol. 2008; 167: 523-529.
13. Benchimol EI, To T, Griffiths AM, et al. Low income children with inflammatory bowel disease have higher surgical and hospitalization rates in a universal health care system. Inflamm Bowel Dis. 2009; 15: S20.
14. Gupta N, Bostrom AG, Kirschner BS, et al. Gender differences in presentation and course of disease in pediatric patients with Crohn disease. Pediatrics. 2007; 120: e1418-1425.
15. Kappelman MD, Rifas-Shiman SL, Porter CQ, et al. Direct health care costs of Crohn's disease and ulcerative colitis in US children and adults. Gastroenterology. 2008; 135: 1907-1913.
16. Cosnes J, Nion-Larmurier I, Beaugerie L, et al. Impact of the increasing use of immunosuppressants in Crohn's disease on the need for intestinal surgery. Gut. 2005; 54: 237-241.
17. Herrinton LJ, Liu L, Fireman B, et al. Time trends in therapies and outcomes for adult inflammatory bowel disease, Northern California, 1998-2005. Gastroenterology. 2009; 137: 502-511.
18. Turner D, Mack D, Leleiko N, et al. Severe pediatric ulcerative colitis: a prospective multicenter study of outcomes and predictors of response. Gastroenterology. 2010; 138: 2282-2291.
19. Guttmann A, Lam K, Schultz SE, et al. Primary care for children. In:, Jaakkimainen L, Upshur REG, Klein-Geltink JE, et al., eds. Primary Care in Ontario: ICES Atlas. Toronto: The Institute for Clinical Evaluative Sciences; 2006: 35-52.
20. Colantonio A, Croxford R, Farooq S, et al. Trends in hospitalization associated with traumatic brain injury in a publicly insured population, 1992-2002. J Trauma. 2009; 66: 179-183.
21. Curtis JR, To T, Muirhead S, et al. Recent trends in hospitalization for diabetic ketoacidosis in Ontario children. Diabetes Care. 2002; 25: 1591-1596.
22. To T, Gershon A, Tassoudji M, et al. The Burden of Asthma in Ontario: ICES Investigative Report. Toronto: The Institute for Clinical Evaluative Sciences; 2006.
23. Baldassano R, Ferry G, Griffiths A, et al. Transition of the patient with inflammatory bowel disease from pediatric to adult care: recommendations of the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition. J Pediatr Gastroenterol Nutr. 2002; 34: 245-248.
24. Van Limbergen J, Russell RK, Drummond HE, et al. Definition of phenotypic characteristics of childhood-onset inflammatory bowel disease. Gastroenterology. 2008; 135: 1114-1122.
25. Shortt SE, Shaw RA, Elliott D, et al. Monitoring trends in waiting periods in Canada for elective surgery: validation of a method using administrative data. Can J Surg. 2004; 47: 173-178.
26. Pinfold SP, Goel V, Sawka C,. Quality of hospital discharge and physician data for type of breast cancer surgery. Med Care. 2000; 38: 99-107.
27. Wijeysundera DN, Austin PC, Hux JE, et al. Development of an algorithm to identify preoperative medical consultations using administrative data. Med Care. 2009; 47: 1258-1264.