Functional organ preservation after chemoradiotherapy in elderly patients with loco-regionally advanced head and neck squamous cell carcinoma

European Archives of Oto-Rhino-Laryngology

Volumn 268, Issue 9, 2011, Pages 1349-1355

  Boscolo Rizzo, Paolo ^a   Muzzi, Enrico ^b   Trabalzini, Franco ^c   Gava, Alessandro ^b   Stellin, Marco ^a   Da Mosto, Maria Cristina ^a  

^a UNIVERSITY OF PADUA MEDICAL SCHOOL   (Italy)

^b TREVISO REGIONAL HOSPITAL   (Italy)

^c UNIVERSITY HOSPITAL OF SIENA   (Italy)

Author keywords

Aged; Chemotherapy; Combined modality therapy; Functional outcome; Head and neck cancer; Radiotherapy

Indexed keywords

CISPLATIN; ELECTROLYTE; FLUOROURACIL;

ADVANCED CANCER; AGED; ANEMIA; ARTICLE; BLOOD CELL COUNT; BRONCHOSCOPY; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CANCER STAGING; CANCER SURVIVAL; CLINICAL ARTICLE; CLINICAL EVALUATION; COMPUTER ASSISTED TOMOGRAPHY; CONTINUOUS INFUSION; ELECTROCARDIOGRAM; ELECTROLYTE BLOOD LEVEL; ESOPHAGOSCOPY; ESOPHAGUS DISEASE; FEBRILE NEUTROPENIA; FEMALE; FIBERSCOPE ENDOSCOPY; FOLLOW UP; GERIATRIC PATIENT; HEAD AND NECK CARCINOMA; HEAD AND NECK SQUAMOUS CELL CARCINOMA; HUMAN; HYPOPHARYNX; KIDNEY DISEASE; LARYNX; LARYNX DISORDER; LIVER FUNCTION TEST; LYMPH NODE METASTASIS; MALE; MOUTH CAVITY; MUCOSAL DISEASE; MULTIMODALITY CANCER THERAPY; NAUSEA; NECK DISSECTION; NEUROLOGIC DISEASE; NEUTROPENIA; NUCLEAR MAGNETIC RESONANCE IMAGING; NUTRITIONAL ASSESSMENT; ORGAN PRESERVATION; OROPHARYNX; OUTCOME ASSESSMENT; OVERALL SURVIVAL; PERCUTANEOUS ENDOSCOPIC GASTROSTOMY; PHARYNX DISEASE; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; PROGRESSION FREE SURVIVAL; RADIATION DOSE FRACTIONATION; SALVAGE THERAPY; SKIN DISEASE; THORAX RADIOGRAPHY; TREATMENT WITHDRAWAL; TUMOR LOCALIZATION; TUMOR VOLUME; VOMITING;

AGE FACTORS; AGED; AGED, 80 AND OVER; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CARCINOMA, SQUAMOUS CELL; CHEMORADIOTHERAPY; CISPLATIN; COHORT STUDIES; COMBINED MODALITY THERAPY; DOSE-RESPONSE RELATIONSHIP, DRUG; DOSE-RESPONSE RELATIONSHIP, RADIATION; FEMALE; FLUOROURACIL; FOLLOW-UP STUDIES; GERIATRIC ASSESSMENT; HEAD AND NECK NEOPLASMS; HUMANS; KAPLAN-MEIER ESTIMATE; MALE; NEOPLASM INVASIVENESS; NEOPLASM STAGING; RADIOTHERAPY, CONFORMAL; RETROSPECTIVE STUDIES; RISK ASSESSMENT; SURVIVAL ANALYSIS; TIME FACTORS; TREATMENT OUTCOME;

EID: 80052775157     PISSN: 09374477     EISSN: 14344726     Source Type: Journal    
DOI: 10.1007/s00405-011-1489-y     Document Type: Article

References (21)

1. DM Parkin F Bray J Ferlay P Pisani 2005 Global cancer statistics, 2002 CA Cancer J Clin 55 74 108 15761078 10.3322/canjclin.55.2.74 (Pubitemid 40372904)
2. J Ferlay DM Parkin E Steliarova-Foucher 2010 Estimates of cancer incidence and mortality in Europe in 2008 Eur J Cancer 46 765 781 20116997 10.1016/j.ejca.2009.12.014 1:STN:280:DC%2BC3c7js1CktA%3D%3D
3. Altekruse SF, Kosary CL, Krapcho M et al (eds) (2010) National Cancer Institute's surveillance, epidemiology, and end results (SEER) cancer statistics review, 1975-2007. National Cancer Institute, Bethesda, MD
4. TY Seiwert EE Cohen 2005 State-of-the-art management of locally advanced head and neck cancer Br J Cancer 92 1341 1348 15846296 10.1038/sj.bjc.6602510 1:CAS:528:DC%2BD2MXjsVSjsb0%3D (Pubitemid 40704997)
5. JP Pignon A le Maître E Maillard J Bourhis MACH-NC Collaborative Group 2009 Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): an update on 93 randomised trials and 17, 346 patients Radiother Oncol 92 4 14 19446902 10.1016/j.radonc.2009.04.014
6. DJ Givens LH Karnell AK Gupta, et al. 2009 Adverse events associated with concurrent chemoradiation therapy in patients with head and neck cancer Arch Otolaryngol Head Neck Surg 135 1209 1217 20026818 10.1001/archoto.2009.174
7. VA Laryngeal cancer study group 1991 Induction chemotherapy plus radiation compared with surgery plus radiation in patients with advanced laryngeal cancer N Engl J Med 324 1685 1690 10.1056/NEJM199106133242402
8. JL Lefebvre D Chevalier B Luboinski A Kirkpatrick L Collette T Sahmoud 1996 Larynx preservation in pyriform sinus cancer: preliminary results of a European Organization for Research and Treatment of Cancer phase III trial. EORTC Head and Neck Cancer Cooperative Group J Natl Cancer Inst 88 890 899 8656441 10.1093/jnci/88.13.890 1:STN:280:DyaK283msV2qsw%3D%3D (Pubitemid 26230640)
9. AA Forastiere H Goepfert M Maor, et al. 2003 Concurrent chemotherapy and radiotherapy for organ preservation in advanced laryngeal cancer N Engl J Med 349 2091 2098 14645636 10.1056/NEJMoa031317 1:CAS:528:DC%2BD3sXptlKiu7s%3D (Pubitemid 37464533)
10. SG Urba J Moon PG Shankar Giri, et al. 2005 Organ preservation for advanced resectable cancer of the base of tongue and hypopharynx: a southwest oncology group trial J Clin Oncol 23 88 95 15625363 10.1200/JCO.2005.04.017 (Pubitemid 41702626)
11. PL Zorat A Paccagnella G Cavaniglia, et al. 2004 Randomized phase III trial of neoadjuvant chemotherapy in head and neck cancer: 10-year follow-up J Natl Cancer Inst 96 1 1714 1717 15547184 1:CAS:528:DC%2BD2cXhtVSqsrzM (Pubitemid 39591589)
12. LL Lin SM Hahn 2009 Combined modality therapy in the elderly population Curr Treat Options Oncol. 10 195 204 19507038 10.1007/s11864-009-0105-5
13. L Balducci G Colloca M Cesari G Gambassi 2009 Assessment and treatment of elderly patients with cancer Surg Oncol 19 3 117 123 10.1016/j.suronc.2009.11. 008 20006489 10.1016/j.suronc.2009.11.008
14. D Bernardi L Barzan G Franchin, et al. 2005 Treatment of head and neck cancer in elderly patients: state of the art and guidelines Crit Rev Oncol Hematol 53 71 80 15607935 10.1016/j.critrevonc.2004.08.001 (Pubitemid 39656110)
15. MP van der Schroeff W Derks GJ Hordijk RJ de Leeuw 2007 The effect of age on survival and quality of life in elderly head and neck cancer patients: a long-term prospective study Eur Arch Otorhinolaryngol 264 415 422 17102957 10.1007/s00405-006-0203-y (Pubitemid 46354908)
16. KN Syrigos D Karachalios EM Karapanagiotou CM Nutting L Manolopoulos KJ Harrington 2009 Head and neck cancer in the elderly: an overview on the treatment modalities Cancer Treat Rev 35 237 245 19100689 10.1016/j.ctrv.2008. 11.002
17. DJ Adelstein JP Saxton LA Rybicki, et al. 2006 Multiagent concurrent chemoradiotherapy for locoregionally advanced squamous cell head and neck cancer: mature results from a single institution J Clin Oncol 24 1064 1071 16505425 10.1200/JCO.2005.01.5867 1:CAS:528:DC%2BD28XislGgsb0%3D (Pubitemid 46638803)
18. SA Bhide M Ahmed Y Barbachano K Newbold KJ Harrington CM Nutting 2008 Sequential induction chemotherapy followed by radical chemo-radiation in the treatment of locoregionally advanced head-and-neck cancer Br J Cancer 99 57 62 18560402 10.1038/sj.bjc.6604444 1:CAS:528:DC%2BD1cXnvFeqs70%3D
19. R Yancik 1997 Cancer burden in the aged: an epidemiologic and demographic overview Cancer 80 1273 1283 9317180 10.1002/(SICI)1097-0142(19971001)80: 7<1273::AID-CNCR13>3.0.CO;2-4 1:STN:280:DyaK2svmtFCquw%3D%3D (Pubitemid 27407230)
20. AR Kreimer GM Clifford P Boyle S Franceschi 2005 Human papillomavirus types in head and neck squamous cell carcinomas worldwide: a systematic review Cancer Epidemiol Biomark Prev 14 467 475 10.1158/1055-9965.EPI-04-0551 1:CAS:528:DC%2BD2MXhs1GhsLg%3D (Pubitemid 40270113)
21. KK Ang J Harris R Wheeler, et al. 2010 Human papillomavirus and survival of patients with oropharyngeal cancer N Engl J Med 363 24 35 20530316 10.1056/NEJMoa0912217 1:CAS:528:DC%2BC3cXpslyjtr8%3D