C-type natriuretic peptide does not attenuate the development of pulmonary hypertension caused by hypoxia and VEGF receptor blockade

Life Sciences

Volumn 89, Issue 13-14, 2011, Pages 460-466

  Casserly, Brian ^b   Mazer, Jeffrey M ^a,b   Vang, Alexander ^a   Harrington, Elizabeth O ^a,b   Klinger, James R ^a,b   Rounds, Sharon ^a,b   Choudhary, Gaurav ^a,b  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b BROWN UNIVERSITY   (United States)

Author keywords

C type natriuretic peptide; Chronic hypoxia; Pulmonary hypertension; SU5416; VEGF receptor blockade

Indexed keywords

NATRIURETIC PEPTIDE TYPE C; PLACEBO; SEMAXANIB; VASCULOTROPIN RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; HEART RIGHT VENTRICLE HYPERTROPHY; HEART RIGHT VENTRICLE PRESSURE; HEART VENTRICLE REMODELING; HYPOXIA; LUNG HEMODYNAMICS; MALE; NONHUMAN; PULMONARY HYPERTENSION; RAT; SYSTOLIC BLOOD PRESSURE;

ANIMALS; ANOXIA; HEMODYNAMICS; HYPERTENSION, PULMONARY; HYPERTROPHY, RIGHT VENTRICULAR; INDOLES; LUNG; MALE; NATRIURETIC AGENTS; NATRIURETIC PEPTIDE, C-TYPE; PROTEIN KINASE INHIBITORS; PYRROLES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, VASCULAR ENDOTHELIAL GROWTH FACTOR;

ANIMALIA; RATTUS;

EID: 80052754998     PISSN: 00243205     EISSN: 18790631     Source Type: Journal    
DOI: 10.1016/j.lfs.2011.07.009     Document Type: Article

References (45)

1. K. Abe Formation of plexiform lesions in experimental severe pulmonary arterial hypertension Circulation 121 25 2010 2747 2754
2. J.M. Aliotta Marrow cell infusion attenuates vascular remodeling in a murine model of monocrotaline-induced pulmonary hypertension Stem Cells Dev 18 5 2009 773 782
3. J. Amin Mechanisms of action of atrial natriuretic factor and C-type natriuretic peptide Hypertension 27 3 Pt 2 1996 684 687 (Pubitemid 26086233)
4. M.B. Anand-Srivastava Natriuretic peptide receptor-C signaling and regulation Peptides 26 6 2005 1044 1059 (Pubitemid 40725375)
5. R. Budhiraja Endothelial dysfunction in pulmonary hypertension Circulation 109 2 2004 159 165 (Pubitemid 38114133)
6. G.L. Colice Exaggerated pulmonary hypertension with monocrotaline in rats susceptible to chronic mountain sickness J Appl Physiol 83 1 1997 25 31 (Pubitemid 27304726)
7. N. Davie ET(A) and ET(B) receptors modulate the proliferation of human pulmonary artery smooth muscle cells Am J Respir Crit Care Med 165 3 2002 398 405 (Pubitemid 34118516)
8. K. Doi C-type natriuretic peptide induces redifferentiation of vascular smooth muscle cells with accelerated reendothelialization Arterioscler Thromb Vasc Biol 21 6 2001 930 936 (Pubitemid 34168648)
9. R.S. Garcha, and A.D. Hughes CNP, but not ANP or BNP, relax human isolated subcutaneous resistance arteries by an action involving cyclic GMP and BKCa channels J Renin Angiotensin Aldosterone Syst 7 2 2006 87 91 (Pubitemid 44383502)
10. D.M. Heublein C-type natriuretic peptide immunoreactivity in human breast vascular endothelial cells Peptides 13 5 1992 1017 1019
11. M. Humbert Treatment of pulmonary arterial hypertension N Engl J Med 351 14 2004 1425 1436
12. T. Itoh C-type natriuretic peptide ameliorates monocrotaline-induced pulmonary hypertension in rats Am J Respir Crit Care Med 170 11 2004 1204 1211 (Pubitemid 39577379)
13. H. Jin Atrial natriuretic peptide attenuates the development of pulmonary hypertension in rats adapted to chronic hypoxia J Clin Invest 85 1 1990 115 120 (Pubitemid 20030298)
14. R.S. Khambata Natriuretic peptide receptor-C underpins the disparate regulation of endothelial and vascular smooth muscle cell proliferation by C-type natriuretic peptide Br J Pharmacol 2011 [Apr 1, Electronic publication ahead of print]. doi: 10.1111/j.1476-5381.2011.01400.x.
15. H. Kimura Alleviation of monocrotaline-induced pulmonary hypertension by antibodies to monocyte chemotactic and activating factor/monocyte chemoattractant protein-1 Lab Invest 78 5 1998 571 581 (Pubitemid 28246981)
16. J.R. Klinger Downregulation of pulmonary atrial natriuretic peptide receptors in rats exposed to chronic hypoxia J Appl Physiol 77 3 1994 1309 1316 (Pubitemid 24299385)
17. J.R. Klinger C-type natriuretic peptide expression and pulmonary vasodilation in hypoxia-adapted rats Am J Physiol 275 4 Pt 1 1998 L645 L652
18. J.R. Klinger Brain natriuretic peptide inhibits hypoxic pulmonary hypertension in rats J Appl Physiol 84 5 1998 1646 1652 (Pubitemid 28225903)
19. J.R. Klinger Pulmonary hemodynamic responses to brain natriuretic peptide and sildenafil in patients with pulmonary arterial hypertension Chest 129 2 2006 417 425 (Pubitemid 43289864)
20. S. Murakami C-type natriuretic peptide attenuates bleomycin-induced pulmonary fibrosis in mice Am J Physiol Lung Cell Mol Physiol 287 6 2004 L1172 L1177 (Pubitemid 39507194)
21. F. Murray Increased expression of the cGMP-inhibited cAMP-specific (PDE3) and cGMP binding cGMP-specific (PDE5) phosphodiesterases in models of pulmonary hypertension Br J Pharmacol 137 8 2002 1187 1194 (Pubitemid 36071735)
22. N. Nagaya Hybrid cell-gene therapy for pulmonary hypertension based on phagocytosing action of endothelial progenitor cells Circulation 108 7 2003 889 895 (Pubitemid 37022134)
23. N. Ohno Accelerated reendothelialization with suppressed thrombogenic property and neointimal hyperplasia of rabbit jugular vein grafts by adenovirus-mediated gene transfer of C-type natriuretic peptide Circulation 105 14 2002 1623 1626 (Pubitemid 34298601)
24. I.R. Preston Synergistic effects of ANP and sildenafil on cGMP levels and amelioration of acute hypoxic pulmonary hypertension Exp Biol Med (Maywood) 229 9 2004 920 925 (Pubitemid 39539377)
25. D. Rahmutula, and D.G. Gardner C-type natriuretic peptide down-regulates expression of its cognate receptor in rat aortic smooth muscle cells Endocrinology 146 11 2005 4968 4974 (Pubitemid 41446636)
26. S. Rich, and B.H. Brundage Pulmonary hypertension: a cellular basis for understanding the pathophysiology and treatment J Am Coll Cardiol 14 3 1989 545 550 (Pubitemid 19229324)
27. H.C. Rosenberg, and M. Rabinovitch Endothelial injury and vascular reactivity in monocrotaline pulmonary hypertension Am J Physiol 255 6 Pt 2 1988 H1484 H1491
28. S. Sakao Initial apoptosis is followed by increased proliferation of apoptosis-resistant endothelial cells FASEB J 19 9 2005 1178 1180 (Pubitemid 40946457)
29. A.E. Schultze, and R.A. Roth Fibrinolytic activity in blood and lungs of rats treated with monocrotaline pyrrole Toxicol Appl Pharmacol 121 1 1993 129 137 (Pubitemid 23221282)
30. R.S. Scotland C-type natriuretic peptide inhibits leukocyte recruitment and platelet-leukocyte interactions via suppression of P-selectin expression Proc Natl Acad Sci USA 102 40 2005 14452 14457 (Pubitemid 41429718)
31. A. Simon Mechanism of C-type natriuretic peptide-induced endothelial cell hyperpolarization Am J Physiol Lung Cell Mol Physiol 296 2 2009 L248 L256
32. K.R. Stenmark Animal models of pulmonary arterial hypertension: the hope for etiological discovery and pharmacological cure Am J Physiol Lung Cell Mol Physiol 297 6 2009 L1013 L1032
33. A.J. Stingo Presence of C-type natriuretic peptide in cultured human endothelial cells and plasma Am J Physiol 263 4 Pt 2 1992 H1318 H1321
34. S. Suga Endothelial production of C-type natriuretic peptide and its marked augmentation by transforming growth factor-beta. Possible existence of "vascular natriuretic peptide system" J Clin Invest 90 3 1992 1145 1149
35. T. Sugita Lung vessel leak precedes right ventricular hypertrophy in monocrotaline-treated rats J Appl Physiol 54 2 1983 371 374 (Pubitemid 13153511)
36. L. Taraseviciene-Stewart Inhibition of the VEGF receptor 2 combined with chronic hypoxia causes cell death-dependent pulmonary endothelial cell proliferation and severe pulmonary hypertension FASEB J 15 2 2001 427 438 (Pubitemid 32141434)
37. H.C. Thomas Monocrotaline pyrrole induces apoptosis in pulmonary artery endothelial cells Toxicol Appl Pharmacol 151 2 1998 236 244 (Pubitemid 128421787)
38. R.M. Tuder Exuberant endothelial cell growth and elements of inflammation are present in plexiform lesions of pulmonary hypertension Am J Pathol 144 2 1994 275 285 (Pubitemid 24165948)
39. R.M. Tuder The pathobiology of pulmonary hypertension Endothelium Clin Chest Med 22 3 2001 405 418
40. R.M. Tuder Pathology of pulmonary hypertension Clin Chest Med 28 1 2007 23 42 vii. (Pubitemid 46335935)
41. A. Vang Activation of endothelial BKCa channels causes pulmonary vasodilation Vascul Pharmacol 53 3-4 2010 122 129
42. C.M. Wei Action of C-type natriuretic peptide in isolated canine arteries and veins Am J Physiol 264 1 Pt 2 1993 H71 H73
43. J. Wharton Antiproliferative effects of phosphodiesterase type 5 inhibition in human pulmonary artery cells Am J Respir Crit Care Med 172 1 2005 105 113 (Pubitemid 40923321)
44. K. Yamahara Significance and therapeutic potential of the natriuretic peptides/cGMP/cGMP-dependent protein kinase pathway in vascular regeneration Proc Natl Acad Sci USA 100 6 2003 3404 3409 (Pubitemid 36356596)
45. Y.D. Zhao Rescue of monocrotaline-induced pulmonary arterial hypertension using bone marrow-derived endothelial-like progenitor cells: efficacy of combined cell and eNOS gene therapy in established disease Circ Res 96 4 2005 442 450 (Pubitemid 40354538)