-
1
-
-
34347393724
-
Therapies directed against epidermal growth factor receptor in aerodigestive carcinomas
-
Karamouzis M.V., Grandis J.R., Argiris A. Therapies directed against epidermal growth factor receptor in aerodigestive carcinomas. JAMA 2007, 298:70-82.
-
(2007)
JAMA
, vol.298
, pp. 70-82
-
-
Karamouzis, M.V.1
Grandis, J.R.2
Argiris, A.3
-
2
-
-
0023942517
-
Growth factor receptor tyrosine kinases
-
Yarden Y., Ullrich A. Growth factor receptor tyrosine kinases. Annu Rev Biochem 1988, 57:443-478.
-
(1988)
Annu Rev Biochem
, vol.57
, pp. 443-478
-
-
Yarden, Y.1
Ullrich, A.2
-
3
-
-
0031963988
-
Prognostic value of ERBB-1, VEGF, cyclin A, FOS, JUN and MYC in patients with squamous cell lung carcinomas
-
Volm M., Rittgen W., Drings P. Prognostic value of ERBB-1, VEGF, cyclin A, FOS, JUN and MYC in patients with squamous cell lung carcinomas. Br J Cancer 1998, 77:663-669.
-
(1998)
Br J Cancer
, vol.77
, pp. 663-669
-
-
Volm, M.1
Rittgen, W.2
Drings, P.3
-
4
-
-
0034777482
-
Epidermal growth factor receptor and HER2-neu mRNA expression in non-small cell lung cancer is correlated with survival
-
Brabender J., Danenberg K.D., Metzger R., Schneider P.M., Park J., Salonga D., et al. Epidermal growth factor receptor and HER2-neu mRNA expression in non-small cell lung cancer is correlated with survival. Clin Cancer Res 2001, 7:1850-1855.
-
(2001)
Clin Cancer Res
, vol.7
, pp. 1850-1855
-
-
Brabender, J.1
Danenberg, K.D.2
Metzger, R.3
Schneider, P.M.4
Park, J.5
Salonga, D.6
-
5
-
-
0142119289
-
Epidermal growth factor receptor in non-small-cell lung carcinomas: correlation between gene copy number and protein expression and impact on prognosis
-
Hirsch F.R., Varella-Garcia M., Bunn P.A., Di Maria M.V., Veve R., Bremmes R.M., et al. Epidermal growth factor receptor in non-small-cell lung carcinomas: correlation between gene copy number and protein expression and impact on prognosis. J Clin Oncol 2003, 21:3798-3807.
-
(2003)
J Clin Oncol
, vol.21
, pp. 3798-3807
-
-
Hirsch, F.R.1
Varella-Garcia, M.2
Bunn, P.A.3
Di Maria, M.V.4
Veve, R.5
Bremmes, R.M.6
-
6
-
-
0012381722
-
Multi-institutional randomized phase II trial of gefitinib for previously treated patients with advanced non-small-cell lung cancer (The IDEAL 1 Trial) [corrected]
-
Fukuoka M., Yano S., Giaccone G., Tamura T., Nakagawa K., Douillard J.Y., et al. Multi-institutional randomized phase II trial of gefitinib for previously treated patients with advanced non-small-cell lung cancer (The IDEAL 1 Trial) [corrected]. J Clin Oncol 2003, 21:2237-2246.
-
(2003)
J Clin Oncol
, vol.21
, pp. 2237-2246
-
-
Fukuoka, M.1
Yano, S.2
Giaccone, G.3
Tamura, T.4
Nakagawa, K.5
Douillard, J.Y.6
-
7
-
-
0142055937
-
Efficacy of gefitinib, an inhibitor of the epidermal growth factor receptor tyrosine kinase, in symptomatic patients with non-small cell lung cancer: a randomized trial
-
Kris M.G., Natale R.B., Herbst R.S., Lynch T.J., Prager D., Belani C.P., et al. Efficacy of gefitinib, an inhibitor of the epidermal growth factor receptor tyrosine kinase, in symptomatic patients with non-small cell lung cancer: a randomized trial. JAMA 2003, 290:2149-2158.
-
(2003)
JAMA
, vol.290
, pp. 2149-2158
-
-
Kris, M.G.1
Natale, R.B.2
Herbst, R.S.3
Lynch, T.J.4
Prager, D.5
Belani, C.P.6
-
8
-
-
1542503746
-
Gefitinib in combination with gemcitabine and cisplatin in advanced non-small-cell lung cancer: a phase III trial-INTACT 1
-
Giaccone G., Herbst R.S., Manegold C., Scagliotti G., Rosell R., Miller V., et al. Gefitinib in combination with gemcitabine and cisplatin in advanced non-small-cell lung cancer: a phase III trial-INTACT 1. J Clin Oncol 2004, 22:777-784.
-
(2004)
J Clin Oncol
, vol.22
, pp. 777-784
-
-
Giaccone, G.1
Herbst, R.S.2
Manegold, C.3
Scagliotti, G.4
Rosell, R.5
Miller, V.6
-
9
-
-
1542713370
-
Gefitinib in combination with paclitaxel and carboplatin in advanced non-small-cell lung cancer: a phase III trial-INTACT 2
-
Herbst R.S., Giaccone G., Schiller J.H., Natale R.B., Miller V., Manegold C., et al. Gefitinib in combination with paclitaxel and carboplatin in advanced non-small-cell lung cancer: a phase III trial-INTACT 2. J Clin Oncol 2004, 22:785-794.
-
(2004)
J Clin Oncol
, vol.22
, pp. 785-794
-
-
Herbst, R.S.1
Giaccone, G.2
Schiller, J.H.3
Natale, R.B.4
Miller, V.5
Manegold, C.6
-
10
-
-
4344646459
-
Determinants of tumor response and survival with erlotinib in patients with non-small-cell lung cancer
-
Perez-Soler R., Chachoua A., Hammond L.A., Rowinsky E.K., Huberman M., Karp D., et al. Determinants of tumor response and survival with erlotinib in patients with non-small-cell lung cancer. J Clin Oncol 2004, 22:3238-3247.
-
(2004)
J Clin Oncol
, vol.22
, pp. 3238-3247
-
-
Perez-Soler, R.1
Chachoua, A.2
Hammond, L.A.3
Rowinsky, E.K.4
Huberman, M.5
Karp, D.6
-
11
-
-
3042531315
-
Bronchioloalveolar carcinoma: a model for investigating the biology of epidermal growth factor receptor inhibition
-
4205s-4209s
-
Gandara D.R., West H., Chansky K., Davies A.M., Lau D.H., Crowley J., et al. Bronchioloalveolar carcinoma: a model for investigating the biology of epidermal growth factor receptor inhibition. Clin Cancer Res 2004, 10. 4205s-4209s.
-
(2004)
Clin Cancer Res
, vol.10
-
-
Gandara, D.R.1
West, H.2
Chansky, K.3
Davies, A.M.4
Lau, D.H.5
Crowley, J.6
-
12
-
-
2642539590
-
Outcomes of patients with advanced non-small cell lung cancer treated with gefitinib (ZD1839, " Iressa" ) on an expanded access study
-
Janne P.A., Gurubhagavatula S., Yeap B.Y., Lucca J., Ostler P., Skarin A.T., et al. Outcomes of patients with advanced non-small cell lung cancer treated with gefitinib (ZD1839, " Iressa" ) on an expanded access study. Lung Cancer 2004, 44:221-230.
-
(2004)
Lung Cancer
, vol.44
, pp. 221-230
-
-
Janne, P.A.1
Gurubhagavatula, S.2
Yeap, B.Y.3
Lucca, J.4
Ostler, P.5
Skarin, A.T.6
-
13
-
-
33646381931
-
Gefitinib therapy in advanced bronchioloalveolar carcinoma: Southwest Oncology Group Study S0126
-
West H.L., Franklin W.A., McCoy J., Gumerlock P.H., Vance R., Lau D.H., et al. Gefitinib therapy in advanced bronchioloalveolar carcinoma: Southwest Oncology Group Study S0126. J Clin Oncol 2006, 24:1807-1813.
-
(2006)
J Clin Oncol
, vol.24
, pp. 1807-1813
-
-
West, H.L.1
Franklin, W.A.2
McCoy, J.3
Gumerlock, P.H.4
Vance, R.5
Lau, D.H.6
-
14
-
-
22044445517
-
Erlotinib in previously treated non-small-cell lung cancer
-
Shepherd F.A., Rodrigues Pereira J., Ciuleanu T., Tan E.H., Hirsh V., Thongprasert S., et al. Erlotinib in previously treated non-small-cell lung cancer. N Engl J Med 2005, 353:123-132.
-
(2005)
N Engl J Med
, vol.353
, pp. 123-132
-
-
Shepherd, F.A.1
Rodrigues Pereira, J.2
Ciuleanu, T.3
Tan, E.H.4
Hirsh, V.5
Thongprasert, S.6
-
15
-
-
4444344330
-
EGF receptor gene mutations are common in lung cancers from " never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib
-
Pao W., Miller V., Zakowski M., Doherty J., Politi K., Sarkaria I., et al. EGF receptor gene mutations are common in lung cancers from " never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib. Proc Natl Acad Sci USA 2004, 101:13306-13311.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 13306-13311
-
-
Pao, W.1
Miller, V.2
Zakowski, M.3
Doherty, J.4
Politi, K.5
Sarkaria, I.6
-
16
-
-
2342471392
-
Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
-
Lynch T.J., Bell D.W., Sordella R., Gurubhagavatula S., Okimoto R.A., Brannigan B.W., et al. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med 2004, 350:2129-2139.
-
(2004)
N Engl J Med
, vol.350
, pp. 2129-2139
-
-
Lynch, T.J.1
Bell, D.W.2
Sordella, R.3
Gurubhagavatula, S.4
Okimoto, R.A.5
Brannigan, B.W.6
-
17
-
-
2342624080
-
EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy
-
Paez J.G., Janne P.A., Lee J.C., Tracy S., Greulich H., Gabriel S., et al. EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science 2004, 304:1497-1500.
-
(2004)
Science
, vol.304
, pp. 1497-1500
-
-
Paez, J.G.1
Janne, P.A.2
Lee, J.C.3
Tracy, S.4
Greulich, H.5
Gabriel, S.6
-
18
-
-
69949186250
-
Screening for epidermal growth factor receptor mutations in lung cancer
-
Rosell R., Moran T., Queralt C., Porta R., Cardenal F., Camps C., et al. Screening for epidermal growth factor receptor mutations in lung cancer. N Engl J Med 2009, 361:958-967.
-
(2009)
N Engl J Med
, vol.361
, pp. 958-967
-
-
Rosell, R.1
Moran, T.2
Queralt, C.3
Porta, R.4
Cardenal, F.5
Camps, C.6
-
19
-
-
77953930730
-
Gefitinib or chemotherapy for non-small-cell lung cancer with mutated EGFR
-
Maemondo M., Inoue A., Kobayashi K., Sugawara S., Oizumi S., Isobe H., et al. Gefitinib or chemotherapy for non-small-cell lung cancer with mutated EGFR. N Engl J Med 2010, 362:2380-2388.
-
(2010)
N Engl J Med
, vol.362
, pp. 2380-2388
-
-
Maemondo, M.1
Inoue, A.2
Kobayashi, K.3
Sugawara, S.4
Oizumi, S.5
Isobe, H.6
-
20
-
-
75249087060
-
Gefitinib versus cisplatin plus docetaxel in patients with non-small-cell lung cancer harbouring mutations of the epidermal growth factor receptor (WJTOG3405): an open label, randomised phase 3 trial
-
Mitsudomi T., Morita S., Yatabe Y., Negoro S., Okamoto I., Tsurutani J., et al. Gefitinib versus cisplatin plus docetaxel in patients with non-small-cell lung cancer harbouring mutations of the epidermal growth factor receptor (WJTOG3405): an open label, randomised phase 3 trial. Lancet Oncol 2010, 11:121-128.
-
(2010)
Lancet Oncol
, vol.11
, pp. 121-128
-
-
Mitsudomi, T.1
Morita, S.2
Yatabe, Y.3
Negoro, S.4
Okamoto, I.5
Tsurutani, J.6
-
21
-
-
69949162760
-
Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma
-
Mok T.S., Wu Y.L., Thongprasert S., Yang C.H., Chu D.T., Saijo N., et al. Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma. N Engl J Med 2009, 361:947-957.
-
(2009)
N Engl J Med
, vol.361
, pp. 947-957
-
-
Mok, T.S.1
Wu, Y.L.2
Thongprasert, S.3
Yang, C.H.4
Chu, D.T.5
Saijo, N.6
-
22
-
-
72449160988
-
A randomized phase III study of gefitinib versus standard chemotherapy (gemcitabine plus cisplatin) as a first-line treatment for never-smokers with advanced or metastatic adenocarcinoma of the lung
-
PRS 4 [abstr]
-
Lee J.S., Park K., Kim S.W., Lee D.H., Kim H.T., Han J.Y., et al. A randomized phase III study of gefitinib versus standard chemotherapy (gemcitabine plus cisplatin) as a first-line treatment for never-smokers with advanced or metastatic adenocarcinoma of the lung. J Thorac Oncol 2009, 4. PRS 4 [abstr].
-
(2009)
J Thorac Oncol
, vol.4
-
-
Lee, J.S.1
Park, K.2
Kim, S.W.3
Lee, D.H.4
Kim, H.T.5
Han, J.Y.6
-
23
-
-
78650837687
-
Final overall survival (OS) results from a phase III, randomised, open-label, first-line study of gefitinib (g) v carboplatin/paclitaxel (c/p) in clinically selected patients with advanced nonsmall cell lung cancer (NSCLC) in Asia (IPASS)
-
LBA 2 [abstr]
-
Yang C.H., Fukuoka M., Mok T.S., Wu Y.L., Thongprasert S., Saijo N., et al. Final overall survival (OS) results from a phase III, randomised, open-label, first-line study of gefitinib (g) v carboplatin/paclitaxel (c/p) in clinically selected patients with advanced nonsmall cell lung cancer (NSCLC) in Asia (IPASS). Ann Oncol 2010, 21. LBA 2 [abstr].
-
(2010)
Ann Oncol
, vol.21
-
-
Yang, C.H.1
Fukuoka, M.2
Mok, T.S.3
Wu, Y.L.4
Thongprasert, S.5
Saijo, N.6
-
24
-
-
75249090732
-
Clinical outcomes of patients with epidermal growth factor receptor (EGFR) mutations (Mut) in IPASS (IRESSATM Pan ASia Study)
-
B9.5 [abstr]
-
Mok T.S., To K.F., Srimunimimit V., Chao T.Y., Ichinose Y., Wu Y.L., et al. Clinical outcomes of patients with epidermal growth factor receptor (EGFR) mutations (Mut) in IPASS (IRESSATM Pan ASia Study). J Thorac Oncol 2009, 4. B9.5 [abstr].
-
(2009)
J Thorac Oncol
, vol.4
-
-
Mok, T.S.1
To, K.F.2
Srimunimimit, V.3
Chao, T.Y.4
Ichinose, Y.5
Wu, Y.L.6
-
25
-
-
5444269445
-
Meta-analyses based on abstracted data: a step in the right direction, but only a first step
-
Piedbois P., Buyse M. Meta-analyses based on abstracted data: a step in the right direction, but only a first step. J Clin Oncol 2004, 22:3839-3841.
-
(2004)
J Clin Oncol
, vol.22
, pp. 3839-3841
-
-
Piedbois, P.1
Buyse, M.2
-
26
-
-
73949154122
-
Genetic abnormalities of the EGFR pathway in African American Patients with non-small-cell lung cancer
-
Leidner R.S., Fu P., Clifford B., Hamdan A., Jin C., Eisenberg R., et al. Genetic abnormalities of the EGFR pathway in African American Patients with non-small-cell lung cancer. J Clin Oncol 2009, 27:5620-5626.
-
(2009)
J Clin Oncol
, vol.27
, pp. 5620-5626
-
-
Leidner, R.S.1
Fu, P.2
Clifford, B.3
Hamdan, A.4
Jin, C.5
Eisenberg, R.6
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