메뉴 건너뛰기




Volumn 10, Issue 4, 2011, Pages 458-468

Danazol improves thrombocytopenia in HCV patients treated with peginterferon and ribavirin

Author keywords

Antiviral therapy; Chronic hepatitis; Platelets; Sustained viral response; Viral hepatitis

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; DANAZOL; FIBRINOGEN; PEGINTERFERON ALPHA2A; RIBAVIRIN; VIRUS RNA;

EID: 80052711329     PISSN: 16652681     EISSN: None     Source Type: Journal    
DOI: 10.1016/s1665-2681(19)31513-3     Document Type: Article
Times cited : (9)

References (38)
  • 1
    • 37349020028 scopus 로고    scopus 로고
    • Hepatitis C: A clinical review
    • Modi AA, Liang TJ. Hepatitis C: a clinical review. Oral Dis 2008; 14: 10-4.
    • (2008) Oral Dis , vol.14 , pp. 10-14
    • Modi, A.A.1    Liang, T.J.2
  • 2
    • 0037179698 scopus 로고    scopus 로고
    • Peginterferon alfa 2a plus ribavirin for chronic hepatitis C virus infection
    • Fried MW, Shiffman ML, Reddy KR, et al. Peginterferon alfa 2a plus ribavirin for chronic hepatitis C virus infection. N Engl J Med 2002; 347: 975-82.
    • (2002) N Engl J Med , vol.347 , pp. 975-982
    • Fried, M.W.1    Shiffman, M.L.2    Reddy, K.R.3
  • 3
    • 77749336543 scopus 로고    scopus 로고
    • Adverse effects of drugs in the treatment of viral hepatitis
    • Negro F. Adverse effects of drugs in the treatment of viral hepatitis, Best Pract Res Clin Gastroenterol 2010; 24: 183-92.
    • (2010) Best Pract Res Clin Gastroenterol , vol.24 , pp. 183-192
    • Negro, F.1
  • 4
    • 0036830507 scopus 로고    scopus 로고
    • Neutropenia during combination therapy of interferon alfa and ribavirin for chronic hepatitis C
    • Soza A, Everhart JE, Ghany MG, et al. Neutropenia during combination therapy of interferon alfa and ribavirin for chronic hepatitis C. Hepatology 2002; 36: 1273-9.
    • (2002) Hepatology , vol.36 , pp. 1273-1279
    • Soza, A.1    Everhart, J.E.2    Ghany, M.G.3
  • 5
    • 0036307087 scopus 로고    scopus 로고
    • Rapid suppression of hematopoiesis by standard or pegylated interferon alpha
    • Peck-Radosavljevic M, Wichlas M, Homoncik-Kraml M, et al. Rapid suppression of hematopoiesis by standard or pegylated interferon alpha. Gastroenterology 2002; 123: 141-51.
    • (2002) Gastroenterology , vol.123 , pp. 141-151
    • Peck-Radosavljevic, M.1    Wichlas, M.2    Homoncik-Kraml, M.3
  • 6
    • 17344363971 scopus 로고    scopus 로고
    • Blunted thrombopoietin response to interferon alfa-induced thrombocytopenia during treatment for hepatitis C
    • Peck-Radosavljevic M, Wichlas M, Pidlich J, et al. Blunted thrombopoietin response to interferon alfa-induced thrombocytopenia during treatment for hepatitis C. Hepatology 1998; 28: 1424-9.
    • (1998) Hepatology , vol.28 , pp. 1424-1429
    • Peck-Radosavljevic, M.1    Wichlas, M.2    Pidlich, J.3
  • 7
    • 77950266142 scopus 로고    scopus 로고
    • Alteration of serum thrombopoietin levels in patients with chronic hepatitis C under interferon therapy
    • Wenzel F, Gruber W, Giers G. Alteration of serum thrombopoietin levels in patients with chronic hepatitis C under interferon therapy. Clin Hemorheol Microcir 2010; 44(2): 137-44.
    • (2010) Clin Hemorheol Microcir , vol.44 , Issue.2 , pp. 137-144
    • Wenzel, F.1    Gruber, W.2    Giers, G.3
  • 8
    • 1842861711 scopus 로고    scopus 로고
    • Danazol therapy in patients with chronic idiopathic thrombocytopenic purpura: Long-term results
    • Maloisel F, Andrès E, Zimmer J, et al. Danazol therapy in patients with chronic idiopathic thrombocytopenic purpura: long-term results. Am J Med 2004; 116: 590-4.
    • (2004) Am J Med , vol.116 , pp. 590-594
    • Maloisel, F.1    Andrès, E.2    Zimmer, J.3
  • 9
    • 1642546472 scopus 로고    scopus 로고
    • Management of immune thrombocytopenic purpura in adults
    • Stasi R, Provan D. Management of immune thrombocytopenic purpura in adults. Mayo Clin Proc 2004; 79: 504-22.
    • (2004) Mayo Clin Proc , vol.79 , pp. 504-522
    • Stasi, R.1    Provan, D.2
  • 10
    • 0024417827 scopus 로고
    • Long-term danazol therapy in autoimmune thrombocytopenia: Unmaintained remission and age-dependent response in women
    • Ahn YS, Rocha R, Mylvaganam R, et al. Long-term danazol therapy in autoimmune thrombocytopenia: unmaintained remission and age-dependent response in women. Ann Intern Med 1989; 111: 723-9.
    • (1989) Ann Intern Med , vol.111 , pp. 723-729
    • Ahn, Y.S.1    Rocha, R.2    Mylvaganam, R.3
  • 11
    • 0024458316 scopus 로고
    • Very low dose danazol in idiopathic thrombocytopenic purpura and its role as an immune modulator
    • Mylvaganam R, Ahn YS, Garcia RO, et al. Very low dose danazol in idiopathic thrombocytopenic purpura and its role as an immune modulator. Am J Med Sci 1989; 298: 215-20.
    • (1989) Am J Med Sci , vol.298 , pp. 215-220
    • Mylvaganam, R.1    Ahn, Y.S.2    Garcia, R.O.3
  • 12
    • 33645351172 scopus 로고    scopus 로고
    • Management of adult idiopathic thrombocytopenic purpura
    • Nakhoul IN, Kozuch P, Varma M. Management of adult idiopathic thrombocytopenic purpura. Clin Adv Hematol Oncol 2006; 4: 136-44.
    • (2006) Clin Adv Hematol Oncol , vol.4 , pp. 136-144
    • Nakhoul, I.N.1    Kozuch, P.2    Varma, M.3
  • 13
    • 0141649539 scopus 로고    scopus 로고
    • Idiopathic thrombocytopenic purpura. A retrospective analysis in 139 patients of the influence of age on the response to corticosteroids, splenectomy and danazol
    • Andrés E, Zimmer J, Noel E, et al. Idiopathic thrombocytopenic purpura. A retrospective analysis in 139 patients of the influence of age on the response to corticosteroids, splenectomy and danazol. Drugs Aging 2003; 20: 841-6.
    • (2003) Drugs Aging , vol.20 , pp. 841-846
    • Andrés, E.1    Zimmer, J.2    Noel, E.3
  • 14
    • 37549018882 scopus 로고    scopus 로고
    • Combined therapy with danazol, pegilated interferon, and ribavirin improves thrombocytopenia and liver injury in rats with fibrosis
    • Cabrera-Álvarez G, Madrid-Marina V, Jimenez-Mendez R, et al. Combined therapy with danazol, pegilated interferon, and ribavirin improves thrombocytopenia and liver injury in rats with fibrosis. Ann Hepatol 2007; 6: 233-41.
    • (2007) Ann Hepatol , vol.6 , pp. 233-241
    • Cabrera-Álvarez, G.1    Madrid-Marina, V.2    Jimenez-Mendez, R.3
  • 15
    • 0035049888 scopus 로고    scopus 로고
    • Declaration of Helsinki
    • World Health Organization
    • World Health Organization. Declaration of Helsinki. Bull World Health Organizat 2001; 79: 373-4.
    • (2001) Bull World Health Organizat , vol.79 , pp. 373-374
  • 16
    • 0004075491 scopus 로고
    • Guidelines for good clinical practice (GCP) for trials on pharmaceutical products
    • World Health Organization
    • World Health Organization. Guidelines for good clinical practice (GCP) for trials on pharmaceutical products. WHO Technical Reports Series 1995; 850.
    • (1995) WHO Technical Reports Series , pp. 850
  • 17
    • 77953287162 scopus 로고    scopus 로고
    • Antiviral therapy in patients with HCV-cirrhosis
    • Melero J, Berenguer M. Antiviral therapy in patients with HCV-cirrhosis. Ann Hepatol 2009; 8: 292-7.
    • (2009) Ann Hepatol , vol.8 , pp. 292-297
    • Melero, J.1    Berenguer, M.2
  • 18
    • 77956268664 scopus 로고    scopus 로고
    • On behalf of the CHARIOT Study Group. Low virological response and high relapse rates in hepatitis C genotype 1 patients with advanced fibrosis despite adequate therapeutic dosing
    • Cheng WS, Roberts SK, McCaughan G, et al; on behalf of the CHARIOT Study Group. Low virological response and high relapse rates in hepatitis C genotype 1 patients with advanced fibrosis despite adequate therapeutic dosing. J Hepatol 2010; 53: 616-23.
    • (2010) J Hepatol , vol.53 , pp. 616-623
    • Cheng, W.S.1    Roberts, S.K.2    McCaughan, G.3
  • 19
    • 63449110734 scopus 로고    scopus 로고
    • Antiviral therapy in hepatitis C virus cirrhotic patients in compensated and decompensated condition
    • Lacobellis A, Ippolito A, Andriulli A. Antiviral therapy in hepatitis C virus cirrhotic patients in compensated and decompensated condition. World J Gastroenterol 2008; 14: 6467-72.
    • (2008) World J Gastroenterol , vol.14 , pp. 6467-6472
    • Lacobellis, A.1    Ippolito, A.2    Andriulli, A.3
  • 20
    • 33747771032 scopus 로고    scopus 로고
    • Autoimmune thrombocytopenia induced by PEG-IFN-alpha plus ribavirin in hepatitis C
    • Demirturk N, Cevik F, Demirdal T, et al. Autoimmune thrombocytopenia induced by PEG-IFN-alpha plus ribavirin in hepatitis C. Platelets 2006; 17: 340-3.
    • (2006) Platelets , vol.17 , pp. 340-343
    • Demirturk, N.1    Cevik, F.2    Demirdal, T.3
  • 21
    • 0346749418 scopus 로고    scopus 로고
    • Possible autoimmune thrombocytopenia associated with pegylated interferon-alpha2a plus ribavirin treatment for hepatitis C
    • Medeiros BC, Seligman PA, Everson GT, et al. Possible autoimmune thrombocytopenia associated with pegylated interferon-alpha2a plus ribavirin treatment for hepatitis C. J Clin Gastroenterol 2004; 38: 84-6.
    • (2004) J Clin Gastroenterol , vol.38 , pp. 84-86
    • Medeiros, B.C.1    Seligman, P.A.2    Everson, G.T.3
  • 22
    • 13244281650 scopus 로고    scopus 로고
    • Treatment of immune thrombocytopenia associated with interferon therapy of hepatitis C with the anti-CD20 monoclonal antibody, rituximab
    • Weitz IC. Treatment of immune thrombocytopenia associated with interferon therapy of hepatitis C with the anti-CD20 monoclonal antibody, rituximab. Am J Hematol 2005; 78: 138-41.
    • (2005) Am J Hematol , vol.78 , pp. 138-141
    • Weitz, I.C.1
  • 23
    • 75649147072 scopus 로고    scopus 로고
    • Considerations in the management of hepatitis C virus-related thrombocytopenia with eltrombopag
    • Danish FA, Koul SS, Subhani FR, Rabbani AE, Yasmin S. Considerations in the management of hepatitis C virus-related thrombocytopenia with eltrombopag. Saudi J Gastroenterol 2010; 16: 51-6.
    • (2010) Saudi J Gastroenterol , vol.16 , pp. 51-56
    • Danish, F.A.1    Koul, S.S.2    Subhani, F.R.3    Rabbani, A.E.4    Yasmin, S.5
  • 24
    • 79952031932 scopus 로고    scopus 로고
    • Eltrombopag-a novel approach for the treatment of chronic immune thrombocytopenic purpura: Review and safety considerations
    • Cook L, Cooper N. Eltrombopag-a novel approach for the treatment of chronic immune thrombocytopenic purpura: review and safety considerations. Drug Design Develop Ther 2010; 4: 139-45.
    • (2010) Drug Design Develop Ther , vol.4 , pp. 139-145
    • Cook, L.1    Cooper, N.2
  • 25
    • 36549001698 scopus 로고    scopus 로고
    • Eltrombopag for the treatment of chronic idiopathic thrombocytopenic purpura
    • Bussel JB, Cheng G, Saleh MN, et al. Eltrombopag for the treatment of chronic idiopathic thrombocytopenic purpura. N Engl J Med 2007; 357: 2237-47.
    • (2007) N Engl J Med , vol.357 , pp. 2237-2247
    • Bussel, J.B.1    Cheng, G.2    Saleh, M.N.3
  • 26
    • 36549047972 scopus 로고    scopus 로고
    • TPL102357 Study Group. Eltrombopag for thrombocytopenia in patients with cirrhosis associated with hepatitis C
    • McHutchison JG, Dusheiko G, Shiffman ML, Rodriguez-Torres M, Sigal S, Bourliere M, et al.; TPL102357 Study Group. Eltrombopag for thrombocytopenia in patients with cirrhosis associated with hepatitis C. N Engl J Med 2007; 357: 2227-36.
    • (2007) N Engl J Med , vol.357 , pp. 2227-2236
    • McHutchison, J.G.1    Dusheiko, G.2    Shiffman, M.L.3    Rodriguez-Torres, M.4    Sigal, S.5    Bourliere, M.6
  • 27
    • 77955384548 scopus 로고    scopus 로고
    • Meta-analysis of factors associated with sustained viral response in patients on hemodialysis treated with standard or pegylated interferon for hepatitis C infection
    • Alavian SM, Tabatabaei SV. Meta-analysis of factors associated with sustained viral response in patients on hemodialysis treated with standard or pegylated interferon for hepatitis C infection. Iran J Kidney Dis 2010; 4: 181-94.
    • (2010) Iran J Kidney Dis , vol.4 , pp. 181-194
    • Alavian, S.M.1    Tabatabaei, S.V.2
  • 29
    • 0033792619 scopus 로고    scopus 로고
    • Prevalence of peripheral blood cytopenias (hypersplenism) in patients with nonalcoholic chronic liver disease
    • Bashour FN, Teran JC, Mullen KD. Prevalence of peripheral blood cytopenias (hypersplenism) in patients with nonalcoholic chronic liver disease. Am J Gastroenterol 2000; 95: 2936-9.
    • (2000) Am J Gastroenterol , vol.95 , pp. 2936-2939
    • Bashour, F.N.1    Teran, J.C.2    Mullen, K.D.3
  • 30
    • 33644785217 scopus 로고    scopus 로고
    • Natural history of compensated cirrhosis in the Child-Pug Class A compared between 490 patients with hepatitis C and 167 with B virus infections
    • Kobayashi M, Ikeda K, Hosaka T, et al. Natural history of compensated cirrhosis in the Child-Pug Class A compared between 490 patients with hepatitis C and 167 with B virus infections. J Med Virol 2006; 78: 459-65.
    • (2006) J Med Virol , vol.78 , pp. 459-465
    • Kobayashi, M.1    Ikeda, K.2    Hosaka, T.3
  • 32
    • 0032871172 scopus 로고    scopus 로고
    • Bleeding problems in patients with liver disease. Ways to manage the many hepatic effects on coagulation
    • Sallah S, Bobzien W. Bleeding problems in patients with liver disease. Ways to manage the many hepatic effects on coagulation. Postgrad Med 1999; 106: 187-195.
    • (1999) Postgrad Med , vol.106 , pp. 187-195
    • Sallah, S.1    Bobzien, W.2
  • 33
    • 0032547944 scopus 로고    scopus 로고
    • Interferon Alfa- 2b alone or in combination with ribavirin for the treatment of relapse of chronic hepatitis C
    • Davis GL, Estevan-Mur R, Rustgi V, et al. Interferon Alfa- 2b alone or in combination with ribavirin for the treatment of relapse of chronic hepatitis C. N Engl J Med 1998; 339: 1493-9.
    • (1998) N Engl J Med , vol.339 , pp. 1493-1499
    • Davis, G.L.1    Estevan-Mur, R.2    Rustgi, V.3
  • 34
    • 43049158112 scopus 로고    scopus 로고
    • Thrombocytopenia associated with chronic liver diseases
    • Afdhal N, McHutchison J, Brown R, et al. Thrombocytopenia associated with chronic liver diseases. J Hepatol 2008; 48: 1000-7.
    • (2008) J Hepatol , vol.48 , pp. 1000-1007
    • Afdhal, N.1    McHutchison, J.2    Brown, R.3
  • 35
    • 35448975065 scopus 로고    scopus 로고
    • The pathophysiology of thrombocytopenia in hepatitis C virus infection and chronic liver disease
    • Wekler BB. The pathophysiology of thrombocytopenia in hepatitis C virus infection and chronic liver disease. Aliment Pharmacol Ther 2007; 26: 13-9.
    • (2007) Aliment Pharmacol Ther , vol.26 , pp. 13-19
    • Wekler, B.B.1
  • 36
    • 1642512630 scopus 로고    scopus 로고
    • Idiopathic thrombocytopenic purpura: Pathophysiology and management
    • Ahn YS, Horstman LL. Idiopathic thrombocytopenic purpura: pathophysiology and management. Int J Hematol 2002; 76: 123-31.
    • (2002) Int J Hematol , vol.76 , pp. 123-131
    • Ahn, Y.S.1    Horstman, L.L.2
  • 37
    • 77954478947 scopus 로고    scopus 로고
    • Interferon reduces the risk of hepatocellular carcinoma in hepatitis C virus-related chronic hepatitis/liver cirrhosis
    • Masuzaki R, Yoshida H, Omata M. Interferon reduces the risk of hepatocellular carcinoma in hepatitis C virus-related chronic hepatitis/liver cirrhosis. Oncology 2010; 78: 17-23.
    • (2010) Oncology , vol.78 , pp. 17-23
    • Masuzaki, R.1    Yoshida, H.2    Omata, M.3
  • 38
    • 0036788338 scopus 로고    scopus 로고
    • Adherence to ombination therapy enhances sustained response in genotype-1 infected patients with chronic hepatitis C
    • McHutchinson JG, Manns M, Patel K, et al. Adherence to ombination therapy enhances sustained response in genotype-1 infected patients with chronic hepatitis C. Gastroenterology 2002; 123: 1061-9.
    • (2002) Gastroenterology , vol.123 , pp. 1061-1069
    • McHutchinson, J.G.1    Manns, M.2    Patel, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.