Agmatine enhances neurogenesis by increasing ERK1/2 expression, and suppresses astrogenesis by decreasing BMP 2,4 and SMAD 1,5,8 expression in subventricular zone neural stem cells

Life Sciences

Volumn 89, Issue 13-14, 2011, Pages 439-449

  Song, Ho Won ^a   Kumar, Bokara Kiran ^a   Kim, Sa Hyun ^a   Jeon, Yong Heui ^a   Lee, Yoon Azalea ^a   Lee, Won Teak ^a   Park, Kyung Ah ^a   Lee, Jong Eun ^a  

^a Yonsei University College of Medicine   (South Korea)

Author keywords

Agmatine; Astrogenesis; BMP 2,4; ERK1 2; Neural stem cell; Neurogenesis; Self renewal; SMAD 1,5,8; Subventricular zone

Indexed keywords

AGMATINE; BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN 4; CASPASE 3; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; SMAD1 PROTEIN; SMAD5 PROTEIN; SMAD8 PROTEIN;

ANIMAL CELL; ARTICLE; CELL COUNT; CELL FATE; CELL PROLIFERATION; CELL SIZE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; FEMALE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MOUSE; NERVE CELL CULTURE; NERVE CELL DIFFERENTIATION; NERVE CELL NECROSIS; NERVOUS SYSTEM DEVELOPMENT; NEURAL STEM CELL; NONHUMAN; PROTEIN EXPRESSION; STEM CELL EXPANSION; SUBVENTRICULAR ZONE; WESTERN BLOTTING;

AGMATINE; ANIMALS; ASTROCYTES; BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN 4; BONE MORPHOGENETIC PROTEINS; CELLS, CULTURED; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION REGULATION, DEVELOPMENTAL; INTERPHASE; LATERAL VENTRICLES; MICE; MICE, INBRED ICR; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; NEURAL STEM CELLS; NEUROGENESIS; NEURONS; SMAD PROTEINS;

EID: 80052700278     PISSN: 00243205     EISSN: 18790631     Source Type: Journal    
DOI: 10.1016/j.lfs.2011.07.003     Document Type: Article

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