IgG autoantibodies against deposited C3 inhibit macrophage-mediated apoptotic cell engulfment in systemic autoimmunity

Journal of Immunology

Volumn 187, Issue 5, 2011, Pages 2101-2111

  Kenyon, Karla D ^a   Cole, Caroline ^a   Crawford, Fran ^a   Kappler, John W ^a   Thurman, Joshua M ^b   Bratton, Donna L ^a   Boackle, Susan A ^b   Henson, Peter M ^a  

^a DEPARTMENT OF MEDICINE   (United States)

^b UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENT COMPONENT C3; COMPLEMENT COMPONENT C3B; DOUBLE STRANDED DNA ANTIBODY; IMMUNOGLOBULIN G ANTIBODY;

ANIMAL CELL; ANTIBODY TITER; APOPTOSIS; ARTICLE; AUTOIMMUNITY; CD4+ T LYMPHOCYTE; CELL SURFACE; COMPLEMENT DEPOSITION; CONTROLLED STUDY; EFFEROCYTOSIS; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; MACROPHAGE; MAJOR CLINICAL STUDY; MOUSE; NONHUMAN; OPSONIZATION; PHAGOCYTOSIS; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; SPLEEN CELL; SYSTEMIC LUPUS ERYTHEMATOSUS;

ANIMALS; APOPTOSIS; AUTOANTIBODIES; AUTOANTIGENS; COMPLEMENT C3; DISEASE MODELS, ANIMAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; IMMUNOGLOBULIN G; LUPUS ERYTHEMATOSUS, SYSTEMIC; MACROPHAGES; MICE; PHAGOCYTOSIS;

EID: 80052683470     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1003468     Document Type: Article

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