In vitro and in vivo antimalarial activity assays of seeds from balanites aegyptiaca: Compounds of the extract show growth inhibition and activity against plasmodial aminopeptidase

Journal of Parasitology Research

Volumn 2011, Issue , 2011, Pages

  Kaiser, Annette ^b,e   Kusch, Peter ^a   Deininger, Susanne ^b   Specht, Sabine ^b   Maniako, Rudeka ^b   Haubrich, Stefanie ^a   Pommerening, Tanja ^c   Lin, Paul Kong Thoo ^d   Hoerauf, Achim ^b  

^a BONN RHEIN SIEG UNIVERSITY OF APPLIED SCIENCES   (Germany)

^b UNIVERSITY OF BONN   (Germany)

^c JOHANNES GUTENBERG UNIVERSITY   (Germany)

^d ROBERT GORDON UNIVERSITY   (United Kingdom)

^e UNIVERSITY OF APPLIED SCIENCES   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

2,4 DI(TERT BUTYL)PHENOL; 2,6 DI TERT BUTYLPHENOL; 6 PHENYL 1,2,4 TRIAZIN 5 ONE OXIME; ASPARTYL AMINOPEPTIDASE; BALANITES AEGYPTIACA EXTRACT; CHLOROQUINE; ENZYME INHIBITOR; PHENOL DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBIOTIC SENSITIVITY; ANTIMALARIAL ACTIVITY; ANTIOXIDANT ACTIVITY; ANTIPROTOZOAL ACTIVITY; ARTICLE; BALANITES; BALANITES AEGYPTIACA; CONTROLLED STUDY; DRUG STRUCTURE; ENZYME INHIBITION; GAS CHROMATOGRAPHY; GROWTH INHIBITION; IN VITRO STUDY; IN VIVO STUDY; MALARIA; MASS SPECTROMETRY; MOUSE; NONHUMAN; PLANT SEED; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; TREATMENT OUTCOME;

BALANITES AEGYPTIACA; MUS; PLASMODIUM FALCIPARUM;

EID: 80052676877     PISSN: 20900023     EISSN: 20900031     Source Type: Journal    
DOI: 10.1155/2011/368692     Document Type: Article

References (24)

1. Fletcher E., Traditional remediessearching their natural sources for the next malaria drug TDR News 2007 79 8 13
2. Ndoye M., Diallo I. Y., Gassama-Dia K., Reproductive biology in Balanites aegyptiaca (L.) Del., a semi-arid forest tree African Journal of Biotechnology 2004 3 1 40 46 (Pubitemid 40746197)
3. Mohamed A. M., Wolf W., Spiess W. E. L., Physical, morphological and chemical characteristics, oil recovery and fatty acid composition of Balanites aegyptiaca Del. kernels Plant Foods for Human Nutrition 2002 57 2 179 189 (Pubitemid 34536026)
4. Neuwinger H. D., Plants used for poison fishing in tropical Africa Toxicon 2004 44 4 417 430 (Pubitemid 39070642)
5. Maregesi S. M., Pieters L., Ngassapa O. D., Apers S., Vingerhoets R., Cos P., Berghe D. A. V., Vlietinck A. J., Screening of some Tanzanian medicinal plants from Bunda district for antibacterial, antifungal and antiviral activities Journal of Ethnopharmacology 2008 119 1 58 66
6. Gnoula C., Mégalizzi V., De Nve N., Sauvage S., Ribaucour F., Guissou P., Duez P., Dubois J., Ingrassia L., Lefranc F., Kiss R., Mijatovic T., Balanitin-6 and -7: diosgenyl saponins isolated from Balanites aegyptiaca Del. display significant anti-tumor activity in vitro and in vivo International Journal of Oncology 2008 32 1 5 15 (Pubitemid 351187428)
7. Kela S. L., Ogunsusi R. A., Ogbogu V. C., Nwude N., Screening of some Nigerian plants for molluscicidal activity Revue d'levage et de Médecine Vétérinaire des Pays Tropicaux 1989 42 2 195 202
8. Koko W. S., Abdalla H. S., Galal M., Khalid H. S., Evaluation of oral therapy on Mansonial Schistosomiasis using single dose of Balanites aegyptiaca fruits and praziquantel Fitoterapia 2005 76 1 30 34 (Pubitemid 40138999)
9. Chapagain B. P., Saharan V., Wiesman Z., Larvicidal activity of saponins from Balanites aegyptiaca callus against Aedes aegypti mosquito Bioresource Technology 2008 99 5 1165 1168 (Pubitemid 350251713)
10. Al Ashaal H. A., Farghaly A. A., Abd El Aziz M. M., Ali M. A., Phytochemical investigation and medicinal evaluation of fixed oil of Balanites aegyptiaca fruits (Balantiaceae) Journal of Ethnopharmacology 2010 127 2 495 501
11. Moloney M. B., Pawluk A. R., Ackland N. R., Plasmodium falciparum growth in deep culture Transactions of the Royal Society of Tropical Medicine and Hygiene 1990 84 4 516 518 (Pubitemid 20266965)
12. Trager W., Williams J., Extracellular (axenic) development in vitro of the erythrocytic cycle of Plasmodium falciparum Proceedings of the National Academy of Sciences of the United States of America 1992 89 12 5351 5355
13. Kaiser A., Gottwald A., Maier W., Seitz H. M., Targeting enzymes involved in spermidine metabolism of parasitic protozoaa possible new strategy for anti-parasitic treatment Parasitology Research 2003 91 6 508 516 (Pubitemid 38021658)
14. Singh S., Puri S. K., Singh S. K., Srivastava R., Gupta R. C., Pandey V. C., Characterization of simian malarial parasite (Plasmodium knowlesi)-induced putrescine transport in rhesus monkey erythrocytes The Journal of Biological Chemistry 1997 272 21 13506 13511
15. Teuscher F., Lowther J., Skinner-Adams T. S., Spielmann T., Dixon M. W. A., Stack C. M., Donnelly S., Mucha A., Kafarski P., Vassiliou S., Gardiner D. L., Dalton J. P., Trenholme K. R., The M18 aspartyl aminopeptidase of the human malaria parasite Plasmodium falciparum The Journal of Biological Chemistry 2007 282 42 30817 30826 (Pubitemid 350041547)
16. M. Eskander, Pharmacological and toxicological effects of Balanites aegyptiaca on laboratory animals, M.S. thesis 1982 Khartoum, Sudan Faculty of Veterinary Medicine, University of Khartoum
17. El-Tahir A., Satti G. M. H., Khalid S. A., Antiplasmodial activity of selected Sudanese medicinal plants with emphasis on Acacia nilotica Phytotherapy Research 1999 13 6 474 478 (Pubitemid 29445763)
18. Hardman R., Sofowora E. A., Biosynthesis of diosgenin in germinating seeds of Balanites aegyptiaca Planta Medica 1971 20 3 193 198
19. Yoon M. A., Jeong T. S., Park D. S., Xu M. Z., Oh H. W., Song K. B., Lee W. S., Park H. Y., Antioxidant effects of quinoline alkaloids and 2,4-di- tert -butylphenol isolated from Scolopendra subspinipes Biological and Pharmaceutical Bulletin 2006 29 4 735 739
20. Mei W. L., Zeng Y. B., Liu J., Dai H. F., GC-MS analysis of volatile constituents from five different kinds of Chinese eaglewood Zhong Yao Cai 2007 30 5 551 555
21. Rana V. S., Blazquez M. A., Constituents of the essential oil of Meriandra bengalensis benth. Leaves from India Essential Oil Research 2007 19 21 22
22. De P. C., Bittrich V., Shepherd G. J., Lopes A. V., Marsaioli A. J., The ecological and taxonomic importance of flower volatiles of Clusia species (Guttiferae) Phytochemistry 2001 56 5 443 452 (Pubitemid 32193090)
23. Malek S. N. A., Shin S. K., Wahab N. A., Yaacob H., Cytotoxic components of Pereskia bleo (Kunth) DC. (Cactaceae) leaves Molecules 2009 14 5 1713 1724
24. Ali B. H., Bashir A. K., Rasheed R. A., Effect of the traditional medicinal plants Rhazya stricta, Balanitis aegyptiaca and Haplophylum tuberculatum on paracetamol-induced hepatotoxicity in mice Phytotherapy Research 2001 15 7 598 603 (Pubitemid 33021866)