The immunodominant CD8 T cell response to the human cytomegalovirus tegument phosphoprotein pp65495-503 epitope critically depends on CD4 T cell help in vaccinated HLA-A*0201 transgenic mice

Journal of Immunology

Volumn 187, Issue 5, 2011, Pages 2172-2180

  Reiser, Michael ^a   Wieland, Andreas ^a,c   Plachter, Bodo ^b   Mertens, Thomas ^a   Greiner, Jochen ^a   Schirmbeck, Reinhold ^a  

^a UNIVERSITY HOSPITAL ULM   (Germany)

^b JOHANNES GUTENBERG UNIVERSITY   (Germany)

^c EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIBODY; CYTOMEGALOVIRUS ANTIGEN PP65; DNA VACCINE; EPITOPE; GAMMA INTERFERON; HLA A ANTIGEN; HLA DR1 ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; FEMALE; HUMAN; HUMAN CELL; HUMAN CYTOMEGALOVIRUS; IMMUNE RESPONSE; IMMUNOGENICITY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEROPREVALENCE; SPLEEN CELL; TRANSGENIC MOUSE;

ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; EPITOPES, T-LYMPHOCYTE; HEK293 CELLS; HLA-A ANTIGENS; HUMANS; IMMUNODOMINANT EPITOPES; LYMPHOCYTE ACTIVATION; MICE; MICE, TRANSGENIC; PHOSPHOPROTEINS; TRANSFECTION; VACCINATION; VIRAL MATRIX PROTEINS;

EID: 80052672715     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1002512     Document Type: Article

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