An innovative severity score index for clostridium difficile infection: A prospective study

Infectious Diseases in Clinical Practice

Volumn 19, Issue 5, 2011, Pages 336-339

  Toro, Doris H ^a   Amaral Mojica, Karla M ^a   Rocha Rodriguez, René ^a   Gutierrez Nuñez, José ^a  

^a VA Caribbean Healthcare System Puerto Rico   (Puerto Rico)

Author keywords

Clostridium difficile; research design scoring methods; severity of illness index

Indexed keywords

ALBUMIN; CLOSTRIDIUM DIFFICILE TOXIN A; CLOSTRIDIUM DIFFICILE TOXIN B; METRONIDAZOLE; VANCOMYCIN;

ABDOMINAL DISTENSION; ABDOMINAL PAIN; AGED; ALBUMIN BLOOD LEVEL; ANTIBIOTIC THERAPY; ARTICLE; ASCITES; CHARLSON COMORBIDITY INDEX; CLOSTRIDIUM DIFFICILE; CLOSTRIDIUM DIFFICILE INFECTION; COLITIS; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE SEVERITY; FEVER; FOLLOW UP; HOSPITAL ADMISSION; HUMAN; HYPOALBUMINEMIA; HYPOTENSION; INTENSIVE CARE UNIT; LEUKOCYTE COUNT; LEUKOCYTOSIS; MAJOR CLINICAL STUDY; MALE; MENTAL HEALTH; MORTALITY; PREDICTION; PROSPECTIVE STUDY; SCORING SYSTEM; SEVERITY SCORE INDEX; TACHYCARDIA;

EID: 80052669422     PISSN: 10569103     EISSN: 15369943     Source Type: Journal    
DOI: 10.1097/IPC.0b013e31821895a8     Document Type: Article

References (20)

1. Zilberberg MD, Shorr AF, Kollef MH. Increase in adult Clostridium difficileYrelated hospitalizations and case-fatality rate, United States, 2000Y2005. Emerg Infect Dis. 2008;14(6):929-931. (Pubitemid 351838602)
2. Pépin J, Valiquette L, Cossette B. Mortality attributable to nosocomial Clostridium difficileYassociated disease during an epidemic caused by a hypervirulent strain in Quebec. CMAJ. 2005;173(9):1037-1042.
3. Kuijper EJ, Coignard B, Tü ll P. Emergence of Clostridium difficileYassociated disease in the North America and Europe. Clin Microbiol Infect. 2006;12(suppl 6):2-18. (Pubitemid 44362038)
4. Nils HZ, Wolfgang E, Ulrich N. Fluoroquinolone resistance and Clostridium difficile, Germany. Emerg Infect Dis. 2010;16(4):675-677.
5. Bo-Moon S, Eun YK, Hyeon MY, et al. Multicentre study of the prevalence of toxigenic Clostridium difficile in Korea: results of a retrospective study 2000-2005. J Med Microbiol. 2008;57:697-701. (Pubitemid 351842060)
6. Quesada-Gomez C, Rodriguez C, Gamboa-Coronado Mdel M, et al. Emergence of Clostridium difficile NAP1 in Latin America. J Clin Microbiol. 2010;48(2):669-670.
7. Zumbado-Salas R, Gamboa-Coronado Mdel M, Rodriguez-Cavallini E, et al. Short report: Clostridium difficile in adult patients with nosocomial diarrhea in a Costa Rican hospital. Am J Trop Med Hyg. 2008;79(2):164-165.
8. Hardt C, Berns T, Treder W, et al. Univariate and multivariate analysis of risk factors for severe Clostridium difficileYassociated diarrhoea: importance of co-morbidity and serum C-reactive protein. World J Gastroenterol. 2008;14(27):4338-4341.
9. Raffat-Jaber M, Olafsson S, Fung WL, et al. Clinical review of the management of fulminant Clostridium difficile infection. Am J Gastroenterol. 2008;103:3195-3203.
10. Kenneally C, Rosini JM, Skrupky LP, et al. Analysis of 30-day mortality for Clostridium difficileYassociated disease in the ICU setting. Chest. 2007;132(2):418-424. (Pubitemid 47282371)
11. Dharmarajan TS, Sipalay M, Shyamsundar R, et al. Co-morbidity, not age predicts adverse outcome in Clostridium difficile colitis. World J Gastroenterol. 2000;6(2):198-201. (Pubitemid 30223594)
12. Kyne L, Merry C, O'Connell B, et al. Factors associated with prolonged symptoms and severe disease due to Clostridium difficile. Age Ageing. 1999;28:107-113. (Pubitemid 29161213)
13. Zuckerman E, Kanel G, Ha C, et al. Low albumin gradient ascites complicating severe pseudomembranous colitis. Gastroenterology. 1997;112(3):991-994. (Pubitemid 27113826)
14. Velazquez-Gomez I, Rocha-Rodriguez R, Toro DH, et al. A severity score index for Clostridium difficile infection. Infect Dis Clin Pract. 2008;16(6):376-378.
15. Charlson ME, Pompei P, Ales KL, et al. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chron Dis. 1987;40:373-383. (Pubitemid 17055592)
16. Institute for Algorithmic Medicine. Comorbidity Index and Score of Charlson et al. Available at: http://www.medal.org/OnlineCalculators/ch1/ch1.13/ ch1.13.01.php. Accessed April 16, 2009.
17. Dubberke ER, Butler AM, Reske KA, et al. Attributable outcomes of endemic Clostridium difficileYassociated disease in non-surgical patients. Emerg Infect Dis. 2008;14(7):1031-1038. (Pubitemid 351920431)
18. Boland GW, Lee MJ, Cats AM, et al. Clostridium difficile colitis: correlation of CT findings with severity of clinical disease. Clin Radiol. 1995;50(3):153-156.
19. Ash L, Baker ME, O'Malley CM, et al. Colonic abnormalities on CT in adult hospitalized patients with Clostridium difficile colitis: prevalence and significance of findings. AJR Am J Roentgenol. 2006;186:1393-400. (Pubitemid 46112578)
20. Cohen SH, Gerding DN, Johnson S, et al. Clinical Practice Guidelines for Clostridium difficile Infection in Adults: 2010 Update by the Society for Healthcare Epidemiology of America (SHEA) and the Infectious Diseases Society of America (IDSA). Infect Control Hosp Epidemiol. 2010;31(5):431-455.