Glomerular filtration rate in early diabetes: Ongoing discussions of causes and mechanisms

Journal of Nephrology

Volumn 24, Issue 5, 2011, Pages 537-540

  Frische, Sebastian ^a  

^a AARHUS UNIVERSITY   (Denmark)

Author keywords

Carbohydrate; Diabetes; Diet; GFR; NaCl

Indexed keywords

ADENOSINE A1 RECEPTOR; SODIUM;

BOWMAN CAPSULE; DIABETES MELLITUS; DIABETIC NEPHROPATHY; GENE DELETION; GLOMERULUS FILTRATION; GLOMERULUS FILTRATION RATE; HUMAN; HYDRAULIC PERMEABILITY; HYDROSTATIC PRESSURE; KIDNEY BLOOD FLOW; KIDNEY TUBULE ABSORPTION; NONHUMAN; ONCOTIC PRESSURE; OSMOTIC DIURESIS; PROGNOSIS; REVIEW; SODIUM RESTRICTION; URINE VOLUME;

ANIMALS; DIABETIC NEPHROPATHIES; DISEASE PROGRESSION; GLOMERULAR FILTRATION RATE; HUMANS; KIDNEY; PROGNOSIS; RISK FACTORS; SODIUM CHLORIDE, DIETARY; TIME FACTORS;

EID: 80052664724     PISSN: 11218428     EISSN: 17246059     Source Type: Journal    
DOI: 10.5301/jn.5000009     Document Type: Review

References (19)

1. Mogensen CE. Twelve shifting paradigms in diabetic renal disease and hypertension. Diabetes Res Clin Pract. 2008;82(Suppl 1):S2-S9.
2. Persson P, Hansell P, Palm F. Tubular reabsorption and diabetes-induced glomerular hyperfiltration. Acta Physiol (Oxf). 2010;200:3-10.
3. Brøchner-Mortensen J, Støckel M, Sørensen PJ, Nielsen AH, Ditzel J. Proximal glomerulo-tubular balance in patients with type 1 (insulin-dependent) diabetes mellitus. Diabetologia. 1984;27:189-192.
4. Vallon V, Richter K, Blantz RC, Thomson S, Osswald H. Glomerular hyperfiltration in experimental diabetes mellitus: potential role of tubular reabsorption. J Am Soc Nephrol. 1999;10:2569-2576.
5. Bank N, Aynedjian HS. Progressive increases in luminal glucose stimulate proximal sodium absorption in normal and diabetic rats. J Clin Invest. 1990;86:309-316.
6. Vallon V. The proximal tubule in the pathophysiology of the diabetic kidney. Am J Physiol Regul Integr Comp Physiol. 2011 Jan 12. [Epub ahead of print].
7. Woods LL, Mizelle HL, Hall JE. Control of renal hemodynamics in hyperglycemia: possible role of tubuloglomerular feedback. Am J Physiol. 1987;252(1 Pt 2):F65-F73.
8. Sällström J, Carlsson P-O, Fredholm BB, Larsson E, Persson AEG, Palm F. Diabetes-induced hyperfiltration in adenosine A(1)-receptor deficient mice lacking the tubuloglomerular feedback mechanism. Acta Physiol (Oxf). 2007;190:253-259.
9. Faulhaber-Walter R, Chen L, Oppermann M, et al. Lack of A1 adenosine receptors augments diabetic hyperfiltration and glomerular injury. J Am Soc Nephrol. 2008;19:722-730.
10. Vallon V, Schroth J, Satriano J, Blantz RC, Thomson SC, Rieg T. Adenosine A(1) receptors determine glomerular hyperfiltration and the salt paradox in early streptozotocin diabetes mellitus. Nephron, Physiol. 2009;111:30-38.
11. Birk C, Richter K, Huang DY, Piesch C, Luippold G, Vallon V. The salt paradox of the early diabetic kidney is independent of renal innervation. Kidney Blood Press Res. 2003;26:344-350.
12. Vallon V, Wead LM, Blantz RC. Renal hemodynamics and plasma and kidney angiotensin II in established diabetes mellitus in rats: effect of sodium and salt restriction. J Am Soc Nephrol. 1995;5:1761-1767.
13. Vallon V, Huang D-Y, Deng A, Richter K, Blantz RC, Thomson S. Salt-sensitivity of proximal reabsorption alters macula densa salt and explains the paradoxical effect of dietary salt on glomerular filtration rate in diabetes mellitus. J Am Soc Nephrol. 2002;13:1865-1871.
14. Miller JA. Renal responses to sodium restriction in patients with early diabetes mellitus. J Am Soc Nephrol. 1997;8:749-755.
15. Bank N, Lahorra G, Aynedjian HS, Wilkes BM. Sodium restriction corrects hyperfiltration of diabetes. Am J Physiol. 1988;254(5 Pt 2):F668-F676.
16. Allen TJ, Waldron MJ, Casley D, Jerums G, Cooper ME. Salt restriction reduces hyperfiltration, renal enlargement, and albuminuria in experimental diabetes. Diabetes. 1997;46:19-24.
17. Vallon V, Kirschenmann D, Wead LM, et al. Effect of chronic salt loading on kidney function in early and established diabetes mellitus in rats. J Lab Clin Med. 1997;130:76-82.
18. Lau C, Sudbury I, Thomson M, Howard PL, Magil AB, Cupples WA. Salt-resistant blood pressure and salt-sensitive renal autoregulation in chronic streptozotocin diabetes. Am J Physiol Regul Integr Comp Physiol. 2009;296:R1761-R1770.
19. O'Neill HA, Kwon T-H, Ring T, et al. Opposing effects of NaCl restriction and carbohydrate loading on urine volume in diabetic rats. Acta Physiol (Oxf). 2011;202:47-57.