Identification and characterization of OXA-48 producing, carbapenem-resistant Enterobacteriaceae isolates in Turkey

Annals of Clinical and Laboratory Science

Volumn 41, Issue 2, 2011, Pages 161-166

  Kilic, Abdullah ^a   Aktas, Zerin ^b   Bedir, Orhan ^a   Gumral, Ramazan ^a   Bulut, Yasemin ^c   Stratton, Charles ^d   Tang, Yi Wei ^d,e   Basustaoglu, A Celal ^a  

^a GULHANE SCHOOL OF MEDICINE   (Turkey)

^b ISTANBUL UNIVERSITY   (Turkey)

^c FIRAT UNIVERSITY   (Turkey)

^d VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e VANDERBILT UNIVERSITY HOSPITAL   (United States)

Author keywords

Antibiotic resistance; Carbapenemase; Enterobacteriaceae; OXA 48

Indexed keywords

AMIKACIN; BETA LACTAMASE; BETA LACTAMASE CTX M; BETA LACTAMASE SHV; BETA LACTAMASE TEM 1; CARBAPENEM; CARBAPENEMASE; MEROPENEM; OXA 48 CARBAPENEMASE; TIGECYCLINE; UNCLASSIFIED DRUG;

ADULT; AGED; ANAMNESIS; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL STRAIN; BACTERIUM ISOLATE; BURKITT LYMPHOMA; CASE REPORT; CHILD; CYSTOCOLIC FISTULA; ENTEROBACTERIACEAE; ENZYME ACTIVATION; ESCHERICHIA COLI; FEMALE; HUMAN; HYDRONEPHROSIS; KLEBSIELLA PNEUMONIAE; LUNG INFILTRATE; MALE; PHYSICAL EXAMINATION; PNEUMONIA; POLYMERASE CHAIN REACTION; PRESCHOOL CHILD; PRIORITY JOURNAL; PULSED FIELD GEL ELECTROPHORESIS; SEQUENCE ANALYSIS; TURKEY (REPUBLIC);

AGED, 80 AND OVER; BETA-LACTAM RESISTANCE; BETA-LACTAMASES; CARBAPENEMS; CHILD, PRESCHOOL; ELECTROPHORESIS, GEL, PULSED-FIELD; ENTEROBACTERIACEAE; ENTEROBACTERIACEAE INFECTIONS; ESCHERICHIA COLI; FEMALE; HUMANS; KLEBSIELLA PNEUMONIAE; MALE; POLYMERASE CHAIN REACTION; TURKEY; YOUNG ADULT;

ENTEROBACTERIACEAE; ESCHERICHIA COLI; KLEBSIELLA PNEUMONIAE;

EID: 80052660330     PISSN: 00917370     EISSN: 15508080     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Deshpande LM, Jones RN, Fritsche TR, Sader HS. Occurrence and characterization of carbapenemase-producing Enterobacteriaceae: report from the SENTRY Antimicrobial Surveillance Program (2000-2004). Microb Drug Resist 2006;12:223-230.
2. Clinical and Laboratory Standards Institute. 2008. Performance standards for antimicrobial susceptibility testing; 18th informational supplement. CLSI document M100-S18. Clinical and Laboratory Standards Institute, Wayne, PA.
3. Clinical and Laboratory Standards Institute. 2006. Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically; approved standard, 7th ed. CLSI document M7-A7. Clinical and Laboratory Standards Institute, Wayne, PA.
4. Anderson KF, Lonsway DR, Rasheed JK, Biddle J, Jensen B, McDougal LK, Carey RB, Thompson A, Stocker S, Limbago B, Patel JB. Evaluation of methods to identify the Klebsiella pneumoniae carbapenemase in Enterobacteriaceae. J Clin Microbiol 2007;45:2723-2725.
5. Lee K, Lim YS, Yong D, Yum JH, Chong Y. Evaluation of the Hodge test and the imipenem-EDTA double-disk synergy test for differentiating metallo-beta-lactamase-producing isolates of Pseudomonas spp. and Acinetobacter spp. J Clin Microbiol 2003;41:4623-4629.
6. Yong D, Lee K, Yum JH, Shin HB, Rossolini GM, Chong Y. Imipenem-EDTA disk method for differentiation of metallobeta-lactamase-producing clinical isolates of Pseudomonas spp. and Acinetobacter spp. J Clin Microbiol 2002;40:3798-3801.
7. Apfalter P, Assadian O, Daxböck F, Hirschl AM, Rotter ML, Makristathis A. Extended double disc synergy testing reveals a low prevalence of extended-spectrum beta-lactamases in Enterobacter spp. in Vienna, Austria. J Antimicrob Chemother 2007;59:854-859.
8. Kilic A, Demiray T, Saracli MA, Bahar G, Aydogan H, Baysallar M, Doganci L. Bacteriological characterization of vancomycinresistant enterococci ina pediatric hospital in Turkey. Ann Microbiol 2004;54:543-551
9. Aktas Z, Kayacan CB, Schneider I, Can B, Midilli K, Bauernfeind A. Carbapenem-hydrolyzing oxacillinase, OXA-48, persists in Klebsiella pneumoniae in Istanbul, Turkey. Chemotherapy 2008;54:101-106.
10. Durmaz R, Otlu B, Koksal F, Hosoglu S, Ozturk R, Ersoy Y, Aktas E, Gursoy NC, Caliskan A. The optimization of a rapid pulsed-field gel electrophoresis protocol for the typing of Acinetobacter baumannii, Escherichia coli and Klebsiella spp. Jpn J Infect Dis 2009;62:372-377.
11. Nordmann P, Poirel L. Emerging carbapenemases in Gram-negative aerobes. Clin Microbiol Infect. 2002;8:321-331.
12. Poirel L, Héritier C, Tolün V, Nordmann P. Emergence of oxacillinase-mediated resistance to imipenem in Klebsiella pneumoniae. Antimicrob Agents Chemother 2004;48:15-22.
13. Nazic H, Poirel L, Nordmann P. Further identification of plasmid-mediated quinolone resistance determinant in Enterobacteriaceae in Turkey. Antimicrob Agents Chemother 2005;49:2146-7214.
14. Gulmez D, Woodford N, Palepou MF, Mushtaq S, Metan G, Yakupogullari Y, Kocagoz S, Uzun O, Hascelik G, Livermore DM. Carbapenem-resistant Escherichia coli and Klebsiella pneumoniae isolates from Turkey with OXA-48-like carbapenemases and outer membrane protein loss. Int J Antimicrob Agents 2008;31:523-526.
15. Carrër A, Poirel L, Eraksoy H, Cagatay AA, Badur S, Nordmann P. Spread of OXA-48-positive carbapenem-resistant Klebsiella pneumoniae isolates in Istanbul, Turkey. Antimicrob Agents Chemother 2008;52:2950-2954.
16. Bratu S, Landman D, Haag R, Recco R, Eramo A, Alam M, Quale J. Rapid spread of carbapenem-resistant Klebsiella pneumoniae in New York City: a new threat to our antibiotic armamentarium. Arch Intern Med 2005;165:1430-1435.
17. Borer A, Saidel-Odes L, Riesenberg K, Eskira S, Peled N, Nativ R, Schlaeffer F, Sherf M. Attributable mortality rate for carbapenem-resistant Klebsiella pneumoniae bacteremia. Infect Control Hosp Epidemiol 2009;30:972-976.
18. Walther-Rasmussen J, Høiby N. OXA-type carbapenemases. J Antimicrob Chemother 2006;57:373-383.
19. Nadkarni AS, Schliep T, Khan L, Zeana CB. Cluster of bloodstream infections caused by KPC-2 carbapenemaseproducing Klebsiella pneumoniae in Manhattan. Am J Infect Control 2009;37:121-126.
20. Gales AC, Reis AO, Jones RN. Contemporary assessment of antimicrobial susceptibility testing methods for polymyxin B and colistin: review of available interpretative criteria and quality control guidelines. J Clin Microbiol 2001;39:183-190.