Effect of treating antibody-coated sperm with chymotrypsin on pregnancy rates following IUI as compared to outcome of IVF/ICSI

Archives of Andrology

Volumn 50, Issue 2, 2004, Pages 93-95

  Check, J H ^a,b   Hourani, W ^a   Check, M L ^a   Graziano, V ^a   Levin, E ^a  

^a RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^b NONE   (United States)

Author keywords

Antisperm antibodies; Intrauterine insemination; Protein digestive enzyme

Indexed keywords

CHYMOTRYPSIN; SPERM ANTIGEN;

ARTICLE; ARTIFICIAL INSEMINATION; CLINICAL ARTICLE; CORRELATION ANALYSIS; DATA ANALYSIS; DRUG COATING; DRUG EFFECT; FERTILIZATION IN VITRO; HUMAN; INTRACYTOPLASMIC SPERM INJECTION; MALE; PREGNANCY RATE; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE; TREATMENT OUTCOME;

ANTIBODIES; CHYMOTRYPSIN; FEMALE; HUMANS; INFERTILITY, MALE; INSEMINATION, ARTIFICIAL; MALE; PREGNANCY; PREGNANCY RATE; RETROSPECTIVE STUDIES; SPERM INJECTIONS, INTRACYTOPLASMIC; SPERMATOZOA;

EID: 80052621208     PISSN: 01485016     EISSN: None     Source Type: Journal    
DOI: 10.1080/01485010490269551     Document Type: Article

References (7)

1. Bollendorf A et al. (1994): The use of chymotrypsin/galactose to treat spermatozoa bound with anti-sperm antibodies prior to intra-uterine insemination. Hum Reprod 9:484-488.
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3. Check M et al. (2000): ICSI as an effective therapy for male factor with antisperm antibodies. Arch Androl 45:125-130.
4. Francavilla F et al. (1992): Failure of intrauterine insemination in male immunological infertility in cases which all spermatozoa are antibody-coated. Fertil Steril 58:587-592.
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7. Nagy ZP et al. (1995): Results of 55 intracytoplasmic sperm injection cycles in the treatment of male-immunological infertility. Hum Reprod 10:1775-1780.