Prognostic Value of 18F-FDG PET in monosegmental stenosis and myelopathy of the cervical spinal cord

Journal of Nuclear Medicine

Volumn 52, Issue 9, 2011, Pages 1385-1391

  Floeth, Frank W ^a,b   Stoffels, Gabriele ^c   Herdmann, Jörg ^a,b   Eicker, Sven ^a   Galldiks, Norbert ^c,d   Steiger, Hans Jakob ^a   Langen, Karl Josef ^c  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b St Vinzenz Hosp   (Germany)

^c FORSCHUNGSZENTRUM JÜLICH   (Germany)

^d UNIVERSITY HOSPITAL OF COLOGNE   (Germany)

Author keywords

18F FDG PET; 18F fluorodeoxyglucose; Cervical myelopathy; Degenerative spinal stenosis; Positron emission tomography; Spinal cord recovery

Indexed keywords

FLUORODEOXYGLUCOSE F 18; DIAGNOSTIC AGENT; RADIOPHARMACEUTICAL AGENT;

ADULT; AGED; ARTICLE; CERVICAL SPINAL CORD; CERVICAL SPINE ANTERIOR FUSION; CLINICAL ARTICLE; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DECOMPRESSION SURGERY; FEMALE; HUMAN; JAPANESE ORTHOPEDIC ASSOCIATION SCORE; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; POSITRON EMISSION TOMOGRAPHY; POSTOPERATIVE PERIOD; PREDICTIVE VALUE; PREOPERATIVE EVALUATION; PRIORITY JOURNAL; PROSPECTIVE STUDY; SCORING SYSTEM; SPINAL CORD DISEASE; SPINE SURGERY; TREATMENT OUTCOME; VERTEBRAL CANAL STENOSIS; CERVICAL SPINE; COMPUTER PROGRAM; IMAGE PROCESSING; METHODOLOGY; MIDDLE AGED; NEUROLOGIC DISEASE; ORTHOPEDIC SURGERY; PROGNOSIS; SCINTISCANNING; SPINAL CORD COMPRESSION; STATISTICAL ANALYSIS;

AGED; AGED, 80 AND OVER; CERVICAL VERTEBRAE; DATA INTERPRETATION, STATISTICAL; FEMALE; FLUORODEOXYGLUCOSE F18; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; NERVOUS SYSTEM DISEASES; ORTHOPEDIC PROCEDURES; POSITRON-EMISSION TOMOGRAPHY; PROGNOSIS; RADIOPHARMACEUTICALS; SOFTWARE; SPINAL CORD COMPRESSION; SPINAL CORD DISEASES; SPINAL STENOSIS; TREATMENT OUTCOME;

EID: 80052617370     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: 10.2967/jnumed.111.091801     Document Type: Article

References (35)

1. Boakye M, Patil CG, Santarelli J, Ho C, Tian W, Lad SP. Cervical spondylotic myelopathy: complications and outcomes after spinal fusion. Neurosurgery. 2008;62:455-461. (Pubitemid 351489279)
2. Alafifi T, Kern R, Fehlings M. Clinical and MRI predictors of outcome after surgical intervention for cervical spondylotic myelopathy. J Neuroimaging. 2007;17:315-322. (Pubitemid 47481066)
3. Kato Y, Kataoka H, Ichihara K, et al. Biomechanical study of cervical flexion myelopathy using a three-dimensional finite element method. J Neurosurg Spine. 2008;8:436-441. (Pubitemid 351792085)
4. Ito T, Oyanagi K, Takahashi H, Takahashi HE, Ikuta F. Cervical spondylotic myelopathy: clinicopathologic study on the progression pattern and thin myelinated fibers of the lesions of seven patients examined during complete autopsy. Spine. 1996;21:827-833. (Pubitemid 26112354)
5. Gilbert JW, Wheeler GR, Spitalieri JR, Mick GE. Prognosis in spine surgery. J Neurosurg Spine. 2008;8:498-499. (Pubitemid 351792100)
6. Mastronardi L, Elsawaf A, Roperto R, et al. Prognostic relevance of the post-operative evolution of intramedullary spinal cord changes in signal intensity on magnetic resonance imaging after anterior decompression for cervical spondylotic myelopathy. J Neurosurg Spine. 2007;7:615-622. (Pubitemid 350291545)
7. Fernández de Rota JJ, Meschian S, Fernández de Rota A, Urbano V, Baron M. Cervical spondylotic myelopathy due to chronic compression: the role of signal intensity changes in magnetic resonance images. J Neurosurg Spine. 2007;6:17-22. (Pubitemid 47066035)
8. Suri A, Chabbra RP, Mehta VS, Gaikwad S, Pandey RM. Effect of intramedullary signal changes on the surgical outcome of patients with cervical spondylotic myelopathy. Spine J. 2003;3:33-45. (Pubitemid 38351771)
9. 18FDG-PET findings of the cervical spinal cord before and after decompressive surgery in patients with compressive myelopathy. Spine. 2009;34:1185-1191.
10. Uchida K, Kobayashi S, Yayama T, et al. Metabolic neuroimaging of the cervical spinal cord in patients with compressive myelopathy: a high-resolution positron emission tomography study. J Neurosurg Spine. 2004;1:72-79. (Pubitemid 38812660)
11. 18F-2-fluoro-deoxy-D-glucose positron emission tomography in cervical compressive myelopathy. Spine. 1999;24:1449-1454.
12. Kamoto Y, Sadato N, Yonekura Y, et al. Visualization of the cervical spinal cord with FDG and high-resolution PET. J Comput Assist Tomogr. 1998;22:487-491. (Pubitemid 28396745)
13. 18F-FDG uptake in the cervical spinal cord in patients with monosegmental chronic cervical myelopathy. Eur Radiol. 2010;20:2925-2932.
14. Japanese Orthopaedic Association. Criteria on the evaluation of treatment of cervical myelopathy. J Jpn Orthop Assoc. 1976;49:addenda 5.
15. Nguyen NC, Sayed MM, Taalab K, Osman MM. Spinal cord metastases from lung cancer: detection with F-18 FDG PET/CT. Clin Nucl Med. 2008;33:356-358. (Pubitemid 351589535)
16. 18F-fluorodeoxyglucose-positron emission tomography. Eur J Surg Oncol. 2005;31:197-204.
17. 18F-FDG PET/CT. J Nucl Med. 2004;45:279-284.
18. Komori T, Delbeke D. Leptomeningeal carcinomatosis and intramedullary spinal cord metastases from lung cancer: detection with FDG positron emission tomography. Clin Nucl Med. 2001;26:905-907. (Pubitemid 33020328)
19. Poggi MM, Patronas N, Buttman JA, Hewitt SM, Fuller B. Intramedullary spinal cord metastasis from renal cell carcinoma: detection by positron emission tomography. Clin Nucl Med. 2001;26:837-839. (Pubitemid 32916824)
20. Wilmshurst JM, Barrington SF, Pritchard D, et al. Positron emission tomography in imaging spinal cord tumors. J Child Neurol. 2000;15:465-472. (Pubitemid 30460230)
21. Meltzer CC, Townsend DW, Kottapally S, Jadali F. FDG imaging of spinal cord primitive neuroectodermal tumor. J Nucl Med. 1998;39:1207-1209. (Pubitemid 28326152)
22. 18F-2-deoxy-glucose in normal and pathological cases. J Comput Assist Tomogr. 1983;7:937-945.
23. Gemmel F, Dumarey N, Palestro CJ. Radionuclide imaging of spinal infections. Eur J Nucl Med Mol Imaging. 2006;33:1226-1237. (Pubitemid 44484480)
24. Popovich T, Carpenter JS, Rai AT, Carson LV, Williams HJ, Marano GD. Spinal cord compression by tophaceous gout with fluorodeoxyglucose-positron- emission tomographic/MR fusion imaging. AJNR Am J Neuroradiol. 2006;27:1201-1203. (Pubitemid 44897626)
25. 18F-FDG PET successfully detects spinal cord sarcoidosis. J Neurol. 2009;256:1943-1946.
26. Dubey N, Miletich RS, Wasay M, Mechtler LL, Bakshi R. Role of fluorodeoxy-glucose positron emission tomography in the diagnosis of neurosarcoidosis. J Neurol Sci. 2002;205:77-81. (Pubitemid 36158997)
27. Nakamoto Y, Tatsumi M, Hammoud D, Cohade C, Osman MM, Wahl RL. Normal FDG distribution patterns in the head and neck: PET/CT evaluation. Radiology. 2005;234:879-885. (Pubitemid 40250832)
28. Uchida K, Baba H, Maezawa Y, Furukawa S, Furusawa N, Imura S. Histological investigation of spinal cord lesions in the spinal hyperostotic mouse (twy/twy): morphological changes in anterior horn cells and immunoreactivity to neurotropic factors. J Neurol. 1998;245:781-793. (Pubitemid 28505273)
29. Baba H, Maezawa Y, Imura S, Kawahara N, Nakahashi K, Tomita K. Quantitative analysis of the spinal cord motoneuron under chronic compression: an experimental observation in the mouse. J Neurol. 1996;243:109-116. (Pubitemid 26026644)
30. Baba H, Maezawa Y, Uchida K, et al. Three-dimensional topographic analysis of spinal accessory motoneurons under chronic mechanical compression: an experimental study in the mouse. J Neurol. 1997;244:222-229. (Pubitemid 27156471)
31. Uchida K, Nakajima H, Takamura T, et al. Neurological improvement associated with resolution of irradiation-induced myelopathy: serial magnetic resonance imaging and positron emission tomography findings. J Neuroimaging. 2009;19:274-276.
32. Chamroonrat W, Posteraro A, El-Haddad G, Zhuang H, Alavi A. Radiation myelopathy visualized as increased FDG uptake on positron emission tomography. Clin Nucl Med. 2005;30:560. (Pubitemid 41026204)
33. Esik O, Emri M, Szakáll S Jr, et al. PET identifies transitional metabolic change in the spinal cord following a subthreshold dose of irradiation. Pathol Oncol Res. 2004;10:42-46. (Pubitemid 38506611)
34. Esik O, Csere T, Stefanits K, et al. Increased metabolic activity in the spinal cord of patients with long-standing Lhermitte's sign. Strahlenther Onkol. 2003;179:690-693. (Pubitemid 37254663)
35. Ozawa H, Sato T, Hyodo H, et al. Clinical significance of intramedullary Gd- DTPA enhancement in cervical myelopathy. Spinal Cord. 2010;48:415-422.