-
1
-
-
17044427681
-
Control of lymphocyte shape and the chemotactic response by the GTP exchange factor Vav
-
Vicente-Manzanares M, Cruz-Adalia A, Martin-Cofreces NB, Cabrero JR, Dosil M, et al. (2005) Control of lymphocyte shape and the chemotactic response by the GTP exchange factor Vav. Blood 105: 3026-3034.
-
(2005)
Blood
, vol.105
, pp. 3026-3034
-
-
Vicente-Manzanares, M.1
Cruz-Adalia, A.2
Martin-Cofreces, N.B.3
Cabrero, J.R.4
Dosil, M.5
-
2
-
-
0035657299
-
SDF-1-induced actin polymerization and migration in human hematopoietic progenitor cells
-
Voermans C, Anthony EC, Mul E, van der Schoot E, Hordijk P, (2001) SDF-1-induced actin polymerization and migration in human hematopoietic progenitor cells. Exp Hematol 29: 1456-1464.
-
(2001)
Exp Hematol
, vol.29
, pp. 1456-1464
-
-
Voermans, C.1
Anthony, E.C.2
Mul, E.3
van der Schoot, E.4
Hordijk, P.5
-
3
-
-
0033209897
-
The chemokine SDF-1alpha triggers CXCR4 receptor dimerization and activates the JAK/STAT pathway
-
Vila-Coro AJ, Rodriguez-Frade JM, Martin De Ana A, Moreno-Ortiz MC, Martinez AC, et al. (1999) The chemokine SDF-1alpha triggers CXCR4 receptor dimerization and activates the JAK/STAT pathway. Faseb J 13: 1699-1710.
-
(1999)
Faseb J
, vol.13
, pp. 1699-1710
-
-
Vila-Coro, A.J.1
Rodriguez-Frade, J.M.2
de Ana Martin, A.3
Moreno-Ortiz, M.C.4
Martinez, A.C.5
-
4
-
-
0035383788
-
Janus kinase 2 is involved in stromal cell-derived factor-1alpha-induced tyrosine phosphorylation of focal adhesion proteins and migration of hematopoietic progenitor cells
-
Zhang XF, Wang JF, Matczak E, Proper JA, Groopman JE, (2001) Janus kinase 2 is involved in stromal cell-derived factor-1alpha-induced tyrosine phosphorylation of focal adhesion proteins and migration of hematopoietic progenitor cells. Blood 97: 3342-3348.
-
(2001)
Blood
, vol.97
, pp. 3342-3348
-
-
Zhang, X.F.1
Wang, J.F.2
Matczak, E.3
Proper, J.A.4
Groopman, J.E.5
-
5
-
-
0034618052
-
Signal transduction by CXC chemokine receptor 4. Stromal cell-derived factor 1 stimulates prolonged protein kinase B and extracellular signal-regulated kinase 2 activation in T lymphocytes
-
Tilton B, Ho L, Oberlin E, Loetscher P, Baleux F, et al. (2000) Signal transduction by CXC chemokine receptor 4. Stromal cell-derived factor 1 stimulates prolonged protein kinase B and extracellular signal-regulated kinase 2 activation in T lymphocytes. J Exp Med 192: 313-324.
-
(2000)
J Exp Med
, vol.192
, pp. 313-324
-
-
Tilton, B.1
Ho, L.2
Oberlin, E.3
Loetscher, P.4
Baleux, F.5
-
6
-
-
0037868184
-
Distinct role of ZAP-70 and Src homology 2 domain-containing leukocyte protein of 76 kDa in the prolonged activation of extracellular signal-regulated protein kinase by the stromal cell-derived factor-1 alpha/CXCL12 chemokine
-
Kremer KN, Humphreys TD, Kumar A, Qian NX, Hedin KE, (2003) Distinct role of ZAP-70 and Src homology 2 domain-containing leukocyte protein of 76 kDa in the prolonged activation of extracellular signal-regulated protein kinase by the stromal cell-derived factor-1 alpha/CXCL12 chemokine. J Immunol 171: 360-367.
-
(2003)
J Immunol
, vol.171
, pp. 360-367
-
-
Kremer, K.N.1
Humphreys, T.D.2
Kumar, A.3
Qian, N.X.4
Hedin, K.E.5
-
7
-
-
33747150625
-
CXCR4 physically associates with the T cell receptor to signal in T cells
-
Kumar A, Humphreys TD, Kremer KN, Bramati PS, Bradfield L, et al. (2006) CXCR4 physically associates with the T cell receptor to signal in T cells. Immunity 25: 213-224.
-
(2006)
Immunity
, vol.25
, pp. 213-224
-
-
Kumar, A.1
Humphreys, T.D.2
Kremer, K.N.3
Bramati, P.S.4
Bradfield, L.5
-
8
-
-
42649122953
-
Blocking on the CXCR4/mTOR signalling pathway induces the anti-metastatic properties and autophagic cell death in peritoneal disseminated gastric cancer cells
-
Hashimoto I, Koizumi K, Tatematsu M, Minami T, Cho S, et al. (2008) Blocking on the CXCR4/mTOR signalling pathway induces the anti-metastatic properties and autophagic cell death in peritoneal disseminated gastric cancer cells. Eur J Cancer 44: 1022-1029.
-
(2008)
Eur J Cancer
, vol.44
, pp. 1022-1029
-
-
Hashimoto, I.1
Koizumi, K.2
Tatematsu, M.3
Minami, T.4
Cho, S.5
-
9
-
-
46749115220
-
CCL5-mediated T-cell chemotaxis involves the initiation of mRNA translation through mTOR/4E-BP1
-
Murooka TT, Rahbar R, Platanias LC, Fish EN, (2008) CCL5-mediated T-cell chemotaxis involves the initiation of mRNA translation through mTOR/4E-BP1. Blood 111: 4892-4901.
-
(2008)
Blood
, vol.111
, pp. 4892-4901
-
-
Murooka, T.T.1
Rahbar, R.2
Platanias, L.C.3
Fish, E.N.4
-
10
-
-
57749119410
-
CXCR6 induces prostate cancer progression by the AKT/mammalian target of rapamycin signaling pathway
-
Wang J, Lu Y, Koch AE, Zhang J, Taichman RS, (2008) CXCR6 induces prostate cancer progression by the AKT/mammalian target of rapamycin signaling pathway. Cancer Res 68: 10367-10376.
-
(2008)
Cancer Res
, vol.68
, pp. 10367-10376
-
-
Wang, J.1
Lu, Y.2
Koch, A.E.3
Zhang, J.4
Taichman, R.S.5
-
13
-
-
75749119313
-
Phosphoinositide 3-kinase and the mammalian target of rapamycin pathways control T cell migration
-
Finlay D, Cantrell D, (2010) Phosphoinositide 3-kinase and the mammalian target of rapamycin pathways control T cell migration. Ann N Y Acad Sci 1183: 149-157.
-
(2010)
Ann N Y Acad Sci
, vol.1183
, pp. 149-157
-
-
Finlay, D.1
Cantrell, D.2
-
14
-
-
42449110816
-
Phosphatidylinositol-3-OH kinase and nutrient-sensing mTOR pathways control T lymphocyte trafficking
-
Sinclair LV, Finlay D, Feijoo C, Cornish GH, Gray A, et al. (2008) Phosphatidylinositol-3-OH kinase and nutrient-sensing mTOR pathways control T lymphocyte trafficking. Nat Immunol 9: 513-521.
-
(2008)
Nat Immunol
, vol.9
, pp. 513-521
-
-
Sinclair, L.V.1
Finlay, D.2
Feijoo, C.3
Cornish, G.H.4
Gray, A.5
-
15
-
-
79251569252
-
Constitutive reductions in mTOR alter cell size, immune cell development, and antibody production
-
Zhang S, Readinger JA, DuBois W, Janka-Junttila M, Robinson R, et al. (2011) Constitutive reductions in mTOR alter cell size, immune cell development, and antibody production. Blood 117: 1228-1238.
-
(2011)
Blood
, vol.117
, pp. 1228-1238
-
-
Zhang, S.1
Readinger, J.A.2
DuBois, W.3
Janka-Junttila, M.4
Robinson, R.5
-
16
-
-
67650312583
-
Ku-0063794 is a specific inhibitor of the mammalian target of rapamycin (mTOR)
-
Garcia-Martinez JM, Moran J, Clarke RG, Gray A, Cosulich SC, et al. (2009) Ku-0063794 is a specific inhibitor of the mammalian target of rapamycin (mTOR). Biochem J 421: 29-42.
-
(2009)
Biochem J
, vol.421
, pp. 29-42
-
-
Garcia-Martinez, J.M.1
Moran, J.2
Clarke, R.G.3
Gray, A.4
Cosulich, S.C.5
-
17
-
-
61349141302
-
Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2
-
Feldman ME, Apsel B, Uotila A, Loewith R, Knight ZA, et al. (2009) Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2. PLoS Biol 7: e38.
-
(2009)
PLoS Biol
, vol.7
-
-
Feldman, M.E.1
Apsel, B.2
Uotila, A.3
Loewith, R.4
Knight, Z.A.5
-
18
-
-
65549145048
-
An ATP-competitive mammalian target of rapamycin inhibitor reveals rapamycin-resistant functions of mTORC1
-
Thoreen CC, Kang SA, Chang JW, Liu Q, Zhang J, et al. (2009) An ATP-competitive mammalian target of rapamycin inhibitor reveals rapamycin-resistant functions of mTORC1. J Biol Chem 284: 8023-8032.
-
(2009)
J Biol Chem
, vol.284
, pp. 8023-8032
-
-
Thoreen, C.C.1
Kang, S.A.2
Chang, J.W.3
Liu, Q.4
Zhang, J.5
-
19
-
-
38849208347
-
Antitumor activity of rapamycin in a Phase I trial for patients with recurrent PTEN-deficient glioblastoma
-
Cloughesy TF, Yoshimoto K, Nghiemphu P, Brown K, Dang J, et al. (2008) Antitumor activity of rapamycin in a Phase I trial for patients with recurrent PTEN-deficient glioblastoma. PLoS Med 5: e8.
-
(2008)
PLoS Med
, vol.5
-
-
Cloughesy, T.F.1
Yoshimoto, K.2
Nghiemphu, P.3
Brown, K.4
Dang, J.5
-
20
-
-
0031764104
-
Chemokines and chemokine receptors in T-cell priming and Th1/Th2-mediated responses
-
Sallusto F, Lanzavecchia A, Mackay CR, (1998) Chemokines and chemokine receptors in T-cell priming and Th1/Th2-mediated responses. Immunol Today 19: 568-574.
-
(1998)
Immunol Today
, vol.19
, pp. 568-574
-
-
Sallusto, F.1
Lanzavecchia, A.2
Mackay, C.R.3
-
21
-
-
32344449778
-
T lymphocytes on the move: chemokines, PI 3-kinase and beyond
-
Ward SG, (2006) T lymphocytes on the move: chemokines, PI 3-kinase and beyond. Trends Immunol 27: 80-87.
-
(2006)
Trends Immunol
, vol.27
, pp. 80-87
-
-
Ward, S.G.1
-
22
-
-
0036342294
-
Identification of the Tuberous Sclerosis Complex-2 Tumor Suppressor Gene Product Tuberin as a Target of the Phosphoinositide 3-Kinase/Akt Pathway
-
Manning BD, Tee AR, Logsdon MN, Blenis J, Cantley LC, (2002) Identification of the Tuberous Sclerosis Complex-2 Tumor Suppressor Gene Product Tuberin as a Target of the Phosphoinositide 3-Kinase/Akt Pathway. Molecular Cell 10: 151-162.
-
(2002)
Molecular Cell
, vol.10
, pp. 151-162
-
-
Manning, B.D.1
Tee, A.R.2
Logsdon, M.N.3
Blenis, J.4
Cantley, L.C.5
-
23
-
-
34250788809
-
AKT/PKB signaling: navigating downstream
-
Manning BD, Cantley LC, (2007) AKT/PKB signaling: navigating downstream. Cell 129: 1261-1274.
-
(2007)
Cell
, vol.129
, pp. 1261-1274
-
-
Manning, B.D.1
Cantley, L.C.2
-
24
-
-
77957157551
-
The multiple faces of CXCL12 (SDF-1alpha) in the regulation of immunity during health and disease
-
Karin N, (2010) The multiple faces of CXCL12 (SDF-1alpha) in the regulation of immunity during health and disease. J Leukoc Biol 88: 463-473.
-
(2010)
J Leukoc Biol
, vol.88
, pp. 463-473
-
-
Karin, N.1
-
25
-
-
67349217986
-
Molecular mechanisms of mTOR-mediated translational control
-
Ma XM, Blenis J, (2009) Molecular mechanisms of mTOR-mediated translational control. Nat Rev Mol Cell Biol 10: 307-318.
-
(2009)
Nat Rev Mol Cell Biol
, vol.10
, pp. 307-318
-
-
Ma, X.M.1
Blenis, J.2
-
26
-
-
0017663695
-
Characterization of a Glucocorticoid-sensitive Human Lymphoid Cell Line
-
Norman MR, Thompson EB, (1977) Characterization of a Glucocorticoid-sensitive Human Lymphoid Cell Line. Cancer Research 37: 3785-3791.
-
(1977)
Cancer Research
, vol.37
, pp. 3785-3791
-
-
Norman, M.R.1
Thompson, E.B.2
-
27
-
-
60249098440
-
Dexamethasone augments CXCR4-mediated signaling in resting human T cells via the activation of the Src kinase Lck
-
Ghosh MC, Baatar D, Collins G, Carter A, Indig F, et al. (2009) Dexamethasone augments CXCR4-mediated signaling in resting human T cells via the activation of the Src kinase Lck. Blood 113: 575-584.
-
(2009)
Blood
, vol.113
, pp. 575-584
-
-
Ghosh, M.C.1
Baatar, D.2
Collins, G.3
Carter, A.4
Indig, F.5
-
28
-
-
70349310357
-
Activation of Wnt5A signaling is required for CXC chemokine ligand 12-mediated T-cell migration
-
Ghosh MC, Collins GD, Vandanmagsar B, Patel K, Brill M, et al. (2009) Activation of Wnt5A signaling is required for CXC chemokine ligand 12-mediated T-cell migration. Blood 114: 1366-1373.
-
(2009)
Blood
, vol.114
, pp. 1366-1373
-
-
Ghosh, M.C.1
Collins, G.D.2
Vandanmagsar, B.3
Patel, K.4
Brill, M.5
-
29
-
-
0036528247
-
Wnt5a signaling directly affects cell motility and invasion of metastatic melanoma
-
Weeraratna AT, Jiang Y, Hostetter G, Rosenblatt K, Duray P, et al. (2002) Wnt5a signaling directly affects cell motility and invasion of metastatic melanoma. Cancer Cell 1: 279-288.
-
(2002)
Cancer Cell
, vol.1
, pp. 279-288
-
-
Weeraratna, A.T.1
Jiang, Y.2
Hostetter, G.3
Rosenblatt, K.4
Duray, P.5
|