Substituted lactam and cyclic azahemiacetals modulate Pseudomonas aeruginosa quorum sensing

Bioorganic and Medicinal Chemistry

Volumn 19, Issue 18, 2011, Pages 5500-5506

  Malladi, Venkata L A ^a   Sobczak, Adam J ^a,b   Maricic, Natalie ^a   Murugapiran, Senthil Kumar ^a   Schneper, Lisa ^a   Makemson, John ^a   Mathee, Kalai ^a   Wnuk, Stanislaw F ^a  

^a FLORIDA INTERNATIONAL UNIVERSITY   (United States)

^b POZNA UNIVERSITY OF LIFE SCIENCES   (Poland)

Author keywords

Azahemiacetals; Azasugars; Pseudomonas aeruginosa; Quorum sensing

Indexed keywords

4 AMINO 4 DEOXY 5 HEXYL 5 THIO ALPHA BETA DEXTRO RIBOFURANOSE; 4 AMINO 4 DEOXY 5 HEXYL 5 THIO DEXTRO RIBONO 1,4 LACTAM; 4 AMINO N (TERT BUTOXYCARBONYL) 4 DEOXY 2,3 O ISOPROPYLIDENE 5 O METHANESUFONYL DEXTRO RIBONO 4,1 LACTAM; 4 AMINO N (TERT BUTOXYCARBONYL) 4 DEOXY 5 HEXYL 2,3 O ISOPROPYLIDENE 5 THIO DEXTRO RIBONO 1,4 LACTAM; 5 (HEXYLTHIOMETHYL)PYRROLIDIN 2 OL; 5 (HEXYLTHIOMETHYL)PYRROLIDIN 2 ONE; 5 (PROPYLTHIOMETHYL)PYRROLIDIN 2 OL; 5 (PROPYLTHIOMETHYL)PYRROLIDIN 2 ONE; ACETAL DERIVATIVE; CYCLIC AZAHEMIACETAL DERIVATIVE; GAMMA LACTAM DERIVATIVE; N TERT BUTOXYCARBONYL 5 (PROPYLTHIOMETHYL)PYRROLIDIN 2 ONE; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL GENE; CHEMICAL MODIFICATION; CONCENTRATION RESPONSE; DRUG DESIGN; DRUG MECHANISM; DRUG POTENCY; DRUG SCREENING; DRUG SOLUBILITY; DRUG STRUCTURE; DRUG SYNTHESIS; GENE EXPRESSION; LAS GENE; NONHUMAN; PSEUDOMONAS AERUGINOSA; QUORUM SENSING; RHL GENE; SIGNAL TRANSDUCTION; STRUCTURE ANALYSIS;

ACETALS; DOSE-RESPONSE RELATIONSHIP, DRUG; LACTAMS; MOLECULAR STRUCTURE; PSEUDOMONAS AERUGINOSA; QUORUM SENSING; SIGNAL TRANSDUCTION; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

NEGIBACTERIA; PSEUDOMONAS AERUGINOSA;

EID: 80052595147     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2011.07.044     Document Type: Article

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