The autophagy gene, ATG18a, plays a negative role in powdery mildew resistance and mildew-induced cell death in Arabidopsis

Plant Signaling and Behavior

Volumn 6, Issue 9, 2011, Pages 1408-1410

  Wang, Yiping ^a,b   Wu, Yingying ^a,b   Tang, Dingzhong ^a  

^a INSTITUTE OF GENETICS AND DEVELOPMENTAL BIOLOGY   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

ATG18a; ATG2; Autophagy; Cell death; Defense response; Powdery mildew

Indexed keywords

ARABIDOPSIS PROTEIN; ATG18A PROTEIN, ARABIDOPSIS; SALICYLIC ACID;

ARABIDOPSIS; ARTICLE; ASCOMYCETES; AUTOPHAGY; CELL DEATH; GENETICS; METABOLISM; MICROBIOLOGY; PATHOGENICITY; PHYSIOLOGY; PLANT DISEASE; PLANT IMMUNITY; SIGNAL TRANSDUCTION;

ARABIDOPSIS; ARABIDOPSIS PROTEINS; ASCOMYCOTA; AUTOPHAGY; CELL DEATH; PLANT DISEASES; PLANT IMMUNITY; SALICYLIC ACID; SIGNAL TRANSDUCTION;

ARABIDOPSIS; ARABIDOPSIS THALIANA; ERYSIPHALES; EUKARYOTA; FUNGI; GOLOVINOMYCES CICHORACEARUM;

EID: 80052585836     PISSN: 15592316     EISSN: 15592324     Source Type: Journal    
DOI: 10.4161/psb.6.9.16967     Document Type: Article

References (23)

1. Wang Y, Nishimura MT, Zhao T, Tang D. ATG2, an autophagy-related protein, negatively affects powdery mildew resistance and mildew-induced cell death in Arabidopsis. Plant J 2011; In press.
2. Klionsky DJ, Ohsumi Y. Vacuolar import of proteins and organelles from the cytoplasm. Annu Rev Cell Dev Biol 1999; 15:1-32.
3. Klionsky DJ. The molecular machinery of autophagy: unanswered questions. J Cell Sci 2005; 118:7-18.
4. Klionsky DJ. Autophagy: from phenomenology to molecular understanding in less than a decade. Nat Rev Mol Cell Biol 2007; 8:931-7.
5. Harding TM, Morano KA, Scott SV, Klionsky DJ. Isolation and characterization of yeast mutants in the cytoplasm to vacuole protein targeting pathway. J Cell Biol 1995; 131:591-602.
6. Thumm M, Egner R, Koch B, Schlumpberger M, Straub M, Veenhuis M, Wolf DH. Isolation of autophagocytosis mutants of Saccharomyces cerevisiae. FEBS Lett 1994; 349:275-80.
7. Tsukada M, Ohsumi Y. Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae. FEBS Lett 1993; 333:169-74.
8. Hanaoka H, Noda T, Shirano Y, Kato T, Hayashi H, Shibata D, et al. Leaf senescence and starvationinduced chlorosis are accelerated by the disruption of an Arabidopsis autophagy gene. Plant Physiol 2002; 129:1181-93.
9. Doelling JH, Walker JM, Friedman EM, Thompson AR, Vierstra RD. The APG8/12-activating enzyme APG7 is required for proper nutrient recycling and senescence in Arabidopsis thaliana. J Biol Chem 2002; 277:33105-14.
10. Yoshimoto K, Takano Y, Sakai Y. Autophagy in plants and phytopathogens. FEBS Lett 2010; 584:1350-8.
11. Yoshimoto K, Hanaoka H, Sato S, Kato T, Tabata S, Noda T, Ohsumi Y. Processing of ATG8s, ubiquitinlike proteins and their deconjugation by ATG4s are essential for plant autophagy. Plant Cell 2004; 16:2967-83.
12. Liu Y, Schiff M, Czymmek K, Talloczy Z, Levine B, Dinesh-Kumar SP. Autophagy regulates programmed cell death during the plant innate immune response. Cell 2005; 121:567-77.
13. Thompson AR, Doelling JH, Suttangkakul A, Vierstra RD. Autophagic nutrient recycling in Arabidopsis directed by the ATG8 and ATG12 conjugation pathways. Plant Physiol 2005; 138:2097-110.
14. Xiong Y, Contento AL, Bassham DC. AtATG18a is required for the formation of autophagosomes during nutrient stress and senescence in Arabidopsis thaliana. Plant J 2005; 42:535-46.
15. Qin G, Ma Z, Zhang L, Xing S, Hou X, Deng J, et al. Arabidopsis AtBECLIN 1/AtATG6/AtVPS30 is essential for pollen germination and plant development. Cell Res 2007; 17:249-63.
16. Phillips AR, Suttangkakul A, Vierstra RD. The ATG12-conjugating enzyme ATG10 Is essential for autophagic vesicle formation in Arabidopsis thaliana. Genetics 2008; 178:1339-53.
17. Yoshimoto K, Jikumaru Y, Kamiya Y, Kusano M, Consonni C, Panstruga R, et al. Autophagy negatively regulates cell death by controlling NPR1-dependent salicylic acid signaling during senescence and the innate immune response in Arabidopsis. Plant Cell 2009; 21:2914-27.
18. Chung T, Phillips AR, Vierstra RD. ATG8 lipidation and ATG8-mediated autophagy in Arabidopsis require ATG12 expressed from the differentially controlled ATG12a and ATG12b loci. Plant J 2010; 62:483-93.
19. Patel S, Dinesh-Kumar SP. Arabidopsis ATG6 is required to limit the pathogen-associated cell death response. Autophagy 2008; 4:20-7.
20. Hofius D, Schultz-Larsen T, Joensen J, Tsitsigiannis DI, Petersen NH, Mattsson O, et al. Autophagic components contribute to hypersensitive cell death in Arabidopsis. Cell 2009; 137:773-83.
21. Lenz HD, Haller E, Melzer E, Kober K, Wurster K, Stahl M, et al. Autophagy differentially controls plant basal immunity to biotrophic and necrotrophic pathogens. Plant J 2011; 66:818-30.
22. Lenz HD, Vierstra RD, Nurnberger T, Gust AA. ATG7 contributes to plant basal immunity towards fungal infection. Plant Signal Behav 2011; 6; In press.
23. Lai Z, Wang F, Zheng Z, Fan B, Chen Z. A critical role of autophagy in plant resistance to necrotrophic fungal pathogens. Plant J 2011; 66:953-68.