Recurrent amplification in the 22q11 region in laryngeal squamous cell carcinoma results in overexpression of the CRKL but not the MAPK1 oncogene

Cancer Biomarkers

Volumn 8, Issue 1, 2010, Pages 11-19

  Kostrzewska Poczekaj, Magdalena ^a   Giefing, MacIej ^a   Jarmuz, Malgorzata ^a   Brauze, Damian ^a   Pelinska, Kinga ^a   Grenman, Reidar ^b   Bartochowska, Anna ^c   Szyfter, Witold ^c   Szyfter, Krzysztof ^a,c  

^a INSTITUTE OF HUMAN GENETICS   (Poland)

^b TURKU UNIVERSITY HOSPITAL   (Finland)

^c POZNAN UNIVERSITY OF MEDICAL SCIENCES   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

CRK LIKE PROTEIN; DNA; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1;

22Q11 REGION; ADULT; AGED; ARTICLE; CARCINOMA CELL; CLINICAL ARTICLE; CONTROLLED STUDY; COPY NUMBER VARIATION; FEMALE; GENE AMPLIFICATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; LARYNGEAL SQUAMOUS CELL CARCINOMA; LARYNX CARCINOMA; MALE; ONCOGENE; PRIORITY JOURNAL; PROMOTER REGION; REAL TIME POLYMERASE CHAIN REACTION; SQUAMOUS CELL CARCINOMA;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AGED; AGED, 80 AND OVER; CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; CHROMOSOMES, HUMAN, PAIR 22; FEMALE; GENE AMPLIFICATION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LARYNGEAL NEOPLASMS; MALE; MIDDLE AGED; MITOGEN-ACTIVATED PROTEIN KINASE 1; NEOPLASM RECURRENCE, LOCAL; NUCLEAR PROTEINS;

EID: 80052583111     PISSN: 15740153     EISSN: 18758592     Source Type: Journal    
DOI: 10.3233/DMA-2011-0814     Document Type: Article

References (23)

1. S.M. Gollin, Chromosomal alterations in squamous cell carcinomas of the head and neck: window to the biology of disease, Head Neck 23(3) (Mar 2001), 238-253. Review.
2. M. Kujawski, M. Rydzanicz, M. Sarlomo-Rikala, A. Gabriel and K. Szyfter, Chromosome alterations reflect clonal evolution in squamous cell carcinoma of the larynx, Med Sci Monit 8(7) (Jul 2002), BR279-BR282.
3. M. Jarmuz, R. Grenman, W. Golusinski and K. Szyfter, Aberrations of 11q13 in laryngeal squamous cell lines and their prognostic significance, Cancer Genet Cytogenet 160 (2005), 82-88. (Pubitemid 40798143)
4. K. Rikimaru, K. Tadokoro, T. Yamamoto, S. Enomoto and N. Tsuchida, Gene amplification and overexpression of epidermal growth factor receptor in squamous cell carcinoma of the head and neck, Head Neck 14(1) (Jan-Feb 1992), 8-13.
5. T. Görögh and U.H. Beier, Gene alterations in head and neck carcinomas and their role in promoting malignant behavior, Int J Oncol 36(3) (2010), 525-532.
6. M. Giefing, J.I. Martin-Subero, K. Kiwerska, M. Jarmuz, R. Grenman, R. Siebert and K. Szyfter, Characterization of ho-mozygous deletions in laryngeal squamous cell carcinoma cell lines, Cancer Genet Cytogenet 184(1) (Jul 2008), 38-43. (Pubitemid 351818227)
7. M. Giefing, N. Zemke, D. Brauze, M. Kostrzewska-Poczekaj, M. Luczak, M. Szaumkessel, K. Pelinska, K. Kiwerska, H. Tonnies, R. Grenman, M. Figlerowicz, R. Siebert, K. Szyfter and M. Jarmuz, High resolution array-CGH and expression profiling identifies PCDH17/PCH68 and PTPRD as tumor suppressor gene candidates in laryngeal squamous cell carcinoma, Genes, Chromosomes and Cancer 50(3) (Mar 2011), 154-166.
8. M. Jarmuz, W. Golusinski, R. Grenman and K. Szyfter, Analysis of chromosome aberrations in cell lines derived from laryngeal cancer in relation to tumor progression, Eur Arch Otorhinolaryngol 259 (2002), 269-273. (Pubitemid 34591725)
9. A.K. Järvinen, R. Autio, S. Haapa-Paananen, M. Wolf, M. Saarela, R. Grénman, I. Leivo, O. Kallioniemi, A.A. Mäkitie and O. Monni, Identification of target genes in laryngeal squa-mous cell carcinoma by high-resolution copy number and gene expression microarray analyses, Oncogene 25(52) (2 Nov 2006), 6997-7008. (Pubitemid 44684840)
10. P. Chomczynski, A reagent for the single-step simultaneous isolation of RNA, DNA and proteins from cell and tissue samples, Biotechniques 15 (1993), 532-534, 536-537.
11. C.B. Foldager, S. Munir, M. Ulrik-Vinther, K. Søballe, C. Bünger and M. Lind, "Validation of suitable house keeping genes for hypoxia-cultured human chondrocytes", BMC Mol Biol 9 (Oct 2009), 10:94.
12. C.A. Pérez-Novo, C. Claeys, F. Speleman, P. Van Cauwen-berge, C. Bachert and J. Vandesompele, Impact of RNA quality on reference gene expression stability, Biotechniques 39(1) (Jul 2005), 52, 54, 56.
13. D. Brauze, M. Widerak, J. Cwykiel, K. Szyfter and W. Baer-Dubowska, The effect of aryl hydrocarbon receptor ligands on the expression of AhR, AhRR, ARNT, Hif1alpha, CYP1A1 andNQO1 genes in rat liver, Toxicol Lett 167 (2006), 212-220. (Pubitemid 44780050)
14. C.L. Andersen, J.L. Jensen and T.F. Orntoft, Normalization of real-time quantitative reverse transcription-PCR data: a model-based variance estimation approach to identify genes suited for normalization, applied to bladder and colon cancer data sets, Cancer Res 64 (2004), 5245-5250. (Pubitemid 39006544)
15. P. Wessa, Pearson Correlation (v1.0.3) in Free Statistics Software (v1. 1.23-r6), Office for Research Development and Education, URL http://www.wessa.net/rwasp-correlation.wasp/, 2008
16. J. ten Hoeve, V. Kaartinen, T. Fioretos, L. Haataja, J.W. Von-cken, N. Heisterkamp and J. Groffen, Cellular interactions of CRKL, and SH2-SH3 adaptor protein, Cancer Res 54(10) (15 May 1994), 2563-2567. (Pubitemid 24173738)
17. M. Sattler and R. Salgia, Role of the adapter protein CRKL in signal transduction of normal hematopoietic and BCR/ABL-transformed cells, Leukemia 12(5) (May 1998), 637-644. (Pubitemid 28220814)
18. C.F Singer, G. Hudelist, W. Lamm, R. Mueller, C. Handl, E. Kubista and K. Czerwenka, Active (p)CrkL is overexpressed in human malignancies: potential role as a surrogate parameter for therapeutic tyrosine kinase inhibition, Oncol Rep 15(2) (Feb 2006), 353-359.
19. Y.H. Kim, K.A. Kwei, L. Girard, K. Salari, J. Kao, M. Pacyna-Gengelbach, P. Wang, T. Hernandez-Boussard, A.F Gazdar, I. Petersen, J.D. Minna and J.R. Pollack, Genomic and functional analysis identifies CRKL as an oncogene amplified in lung cancer, Oncogene 29(10) (11 Mar 2010), 1421-1430. Epub 2009 Dec 7.
20. U. Bockmühl, A. Schwendel, M. Dietel and I. Petersen, Distinct patterns of chromosomal alterations in high-and low-grade head and neck squamous cell carcinomas, Cancer Res 56(23) (1 Dec 1996), 5325-5329. (Pubitemid 27011356)
21. A.K. Järvinen, R. Autio, S. Kilpinen, M. Saarela, I. Leivo, R. Grénman, A.A. Mäkitie and O. Monni, High-resolution copy number and gene expression microarray analyses of head and neck squamous cell carcinoma cell lines of tongue and larynx, Genes Chromosomes Cancer 47(6) (Jun 2008), 500-509. (Pubitemid 351657185)
22. L.G. Shaffer, C. McCaskill, J.Y. Han, K.H. Choo, D.M. Cutil-lo, A.E. Donnenfeld, L. Weiss and D.L. Van Dyke, Molecular characterization of de novo secondary trisomy 13, Am J Hum Genet 55(5) (Nov 1994), 968-974. (Pubitemid 24334290)
23. S.M. Feller, Crk family adaptors-signalling complex formation and biological roles, Oncogene 20(44) (1 Oct 2001), 6348-6371. (Pubitemid 32977844)