-
1
-
-
0030045003
-
Structure and mechanism of DNA topoisomerase II
-
DOI 10.1038/379225a0
-
JM Berger SJ Gamblin SC Harrison JC Wang 1996 Structure and mechanism of DNA topoisomerase II Nature 379 225 232 8538787 10.1038/379225a0 1:CAS:528:DyaK28Xmtl2gsg%3D%3D (Pubitemid 26025206)
-
(1996)
Nature
, vol.379
, Issue.6562
, pp. 225-232
-
-
Berger, J.M.1
Gamblin, S.J.2
Harrison, S.C.3
Wang, J.C.4
-
2
-
-
0036227720
-
Culprit and victim - DNA topoisomerase II
-
DOI 10.1016/S1470-2045(02)00715-5
-
U Kellner M Sehested PB Jensen F Gieseler P Rudolph 2002 Culprit and victim-DNA topoisomerase II Lancet Oncol 3 235 243 12067686 10.1016/S1470- 2045(02)00715-5 1:CAS:528:DC%2BD38XjsFWjs7Y%3D (Pubitemid 34436660)
-
(2002)
Lancet Oncology
, vol.3
, Issue.4
, pp. 235-243
-
-
Kellner, U.1
Sehested, M.2
Jensen, P.B.3
Gieseler, F.4
Rudolph, P.5
-
3
-
-
70449708986
-
The role of topoisomerase IIalpha and HER-2 in predicting sensitivity to anthracyclines in breast cancer patients
-
19758759 10.1016/j.ctrv.2009.08.006 1:CAS:528:DC%2BD1MXhsVGlsb3J
-
C Oakman E Moretti F Galardi L Santarpia A Di Leo 2009 The role of topoisomerase IIalpha and HER-2 in predicting sensitivity to anthracyclines in breast cancer patients Cancer Treat Rev 35 662 667 19758759 10.1016/j.ctrv.2009. 08.006 1:CAS:528:DC%2BD1MXhsVGlsb3J
-
(2009)
Cancer Treat Rev
, vol.35
, pp. 662-667
-
-
Oakman, C.1
Moretti, E.2
Galardi, F.3
Santarpia, L.4
Di Leo, A.5
-
4
-
-
7444252789
-
Topoisomerase-IIα expression as a predictive marker in a population of advanced breast cancer patients randomly treated either with single-agent doxorubicin or single-agent docetaxel
-
V Durbecq M Paesmans F Cardoso, et al. 2004 Topoisomerase-II alpha expression as a predictive marker in a population of advanced breast cancer patients randomly treated either with single-agent doxorubicin or single-agent docetaxel Mol Cancer Ther 3 1207 1214 15486187 1:CAS:528:DC%2BD2cXosVSrs74%3D (Pubitemid 39440165)
-
(2004)
Molecular Cancer Therapeutics
, vol.3
, Issue.10
, pp. 1207-1214
-
-
Durbecq, V.1
Paesmans, M.2
Cardoso, F.3
Desmedt, C.4
Di Leo, A.5
Chan, S.6
Friedrichs, K.7
Pinter, T.8
Van Belle, S.9
Murray, E.10
Bodrogi, I.11
Walpole, E.12
Lesperance, B.13
Korec, S.14
Crown, J.15
Simmonds, P.16
Perren, J.T.J.17
Leroy, J.-Y.18
Rouas, G.19
Sotiriou, C.20
Piccart, M.21
Larsimont, D.22
more..
-
5
-
-
0036091354
-
HER-2 amplification and topoisomerase IIα gene aberrations as predictive markers in node-positive breast cancer patients randomly treated either with an anthracycline-based therapy or with cyclophosphamide, methotrexate, and 5-fluorouracil
-
A Di Leo D Gancberg D Larsimont, et al. 2002 HER-2 amplification and topoisomerase IIalpha gene aberrations as predictive markers in node-positive breast cancer patients randomly treated either with an anthracycline-based therapy or with cyclophosphamide, methotrexate, and 5-fluorouracil Clin Cancer Res 8 1107 1116 12006526 1:CAS:528:DC%2BD38XksVSqu7s%3D (Pubitemid 34517647)
-
(2002)
Clinical Cancer Research
, vol.8
, Issue.5
, pp. 1107-1116
-
-
Di Leo, A.1
Gancberg, D.2
Larsimont, D.3
Tanner, M.4
Jarvinen, T.5
Rouas, G.6
Dolci, S.7
Leroy, J.-Y.8
Paesmans, M.9
Isola, J.10
Piccart, M.J.11
-
6
-
-
4444249420
-
Serial topoisomerase II expression in primary breast cancer and response to neoadjuvant anthracycline-based chemotherapy
-
DOI 10.1159/000079487
-
M Martin-Richard M Munoz J Albanell, et al. 2004 Serial topoisomerase II expression in primary breast cancer and response to neoadjuvant anthracycline-based chemotherapy Oncology 66 388 394 15331926 10.1159/000079487 1:CAS:528:DC%2BD2cXntFSgt74%3D (Pubitemid 39194361)
-
(2004)
Oncology
, vol.66
, Issue.5
, pp. 388-394
-
-
Martin-Richard, M.1
Munoz, M.2
Albanell, J.3
Colomo, L.4
Bellet, M.5
Rey, M.J.6
Tabernero, J.7
Alonso, C.8
Cardesa, A.9
Gascon, P.10
Fernandez, P.L.11
-
7
-
-
0043236239
-
DNA topoisomerase IIα expression and the response to primary chemotherapy in breast cancer
-
DOI 10.1038/sj.bjc.6601185
-
G MacGrogan P Rudolph I Mascarel Id, et al. 2003 DNA topoisomerase IIalpha expression and the response to primary chemotherapy in breast cancer Br J Cancer 89 666 671 12915875 10.1038/sj.bjc.6601185 1:CAS:528: DC%2BD3sXmtFKqtrg%3D (Pubitemid 37076170)
-
(2003)
British Journal of Cancer
, vol.89
, Issue.4
, pp. 666-671
-
-
MacGrogan, G.1
Rudolph, P.2
De Mascarel, I.3
Mauriac, L.4
Durand, M.5
Avril, A.6
Dilhuydy, J.M.7
Robert, J.8
Mathoulin-Pelissier, S.9
Picot, V.10
Floquet, A.11
Sierankowski, G.12
Coindre, J.M.13
-
8
-
-
0036554731
-
Amplification and overexpression of topoisomerase IIα predict response to anthracycline-based therapy in locally advanced breast cancer
-
JS Coon E Marcus S Gupta-Burt S Seelig K Jacobson S Chen V Renta G Fronda HD Preisler 2002 Amplification and overexpression of topoisomerase IIalpha predict response to anthracycline-based therapy in locally advanced breast cancer Clin Cancer Res 8 1061 1067 11948114 1:CAS:528:DC%2BD38XjsF2ltr8%3D (Pubitemid 35177356)
-
(2002)
Clinical Cancer Research
, vol.8
, Issue.4
, pp. 1061-1067
-
-
Coon, J.S.1
Marcus, E.2
Gupta-Burt, S.3
Seelig, S.4
Jacobson, K.5
Chen, S.6
Renta, V.7
Fronda, G.8
Preisler, H.D.9
-
9
-
-
0037333625
-
Topoisomerase II-α (topoII) and HER2 amplification in breast cancers and response to preoperative doxorubicin chemotherapy
-
DOI 10.1016/S0959-8049(02)00745-1, PII S0959804902007451
-
K Park J Kim S Lim S Han 2003 Topoisomerase II-alpha (topoII) and HER2 amplification in breast cancers and response to preoperative doxorubicin chemotherapy Eur J Cancer 39 631 634 12628842 10.1016/S0959-8049(02)00745-1 1:CAS:528:DC%2BD3sXhvFGkurk%3D (Pubitemid 36287375)
-
(2003)
European Journal of Cancer
, vol.39
, Issue.5
, pp. 631-634
-
-
Park, K.1
Kim, J.2
Lim, S.3
Han, S.4
-
10
-
-
74549120081
-
Predicting the efficacy of anthracyclines in breast cancer (BC) patients: Results of the neoadjuvant TOP trial
-
C Desmedt E Azambuja D Larsimont, et al. 2009 Predicting the efficacy of anthracyclines in breast cancer (BC) patients: results of the neoadjuvant TOP trial J Clin Oncol 27 523
-
(2009)
J Clin Oncol
, vol.27
, pp. 523
-
-
Desmedt, C.1
Azambuja, E.2
Larsimont, D.3
-
11
-
-
3843120055
-
Correlation between complete response to anthracycline-based chemotherapy and topoisomerase II-alpha gene amplification and protein overexpression in locally advanced/metastatic breast cancer
-
14654958 1:CAS:528:DC%2BD2cXktlWhtw%3D%3D
-
F Cardoso V Durbecq D Larsimont, et al. 2004 Correlation between complete response to anthracycline-based chemotherapy and topoisomerase II-alpha gene amplification and protein overexpression in locally advanced/metastatic breast cancer Int J Oncol 24 201 209 14654958 1:CAS:528:DC%2BD2cXktlWhtw%3D%3D
-
(2004)
Int J Oncol
, vol.24
, pp. 201-209
-
-
Cardoso, F.1
Durbecq, V.2
Larsimont, D.3
-
12
-
-
0031775808
-
Predictive value of topoisomerase IIα and other prognostic factors for epirubicin chemotherapy in advanced breast cancer
-
TA Jarvinen K Holli T Kuukasjarvi JJ Isola 1998 Predictive value of topoisomerase IIalpha and other prognostic factors for epirubicin chemotherapy in advanced breast cancer Br J Cancer 77 2267 2273 9649144 10.1038/bjc.1998.377 1:CAS:528:DyaK1cXktlCmtbo%3D (Pubitemid 28263952)
-
(1998)
British Journal of Cancer
, vol.77
, Issue.12
, pp. 2267-2273
-
-
Jarvinen, T.A.H.1
Holli, K.2
Kuukasjarvi, T.3
Isola, J.J.4
-
13
-
-
32944475493
-
Retrospective analysis of topoisomerase IIa amplifications and deletions as predictive markers in primary breast cancer patients randomly assigned to cyclophosphamide, methotrexate, and fluorouracil or cyclophosphamide, epirubicin, and fluorouracil: Danish Breast Cancer Cooperative Group
-
DOI 10.1200/JCO.2005.11.007
-
AS Knoop H Knudsen E Balslev, et al. 2005 Retrospective analysis of topoisomerase IIa amplifications and deletions as predictive markers in primary breast cancer patients randomly assigned to cyclophosphamide, methotrexate, and fluorouracil or cyclophosphamide, epirubicin, and fluorouracil: Danish Breast Cancer Cooperative Group J Clin Oncol 23 7483 7490 16234514 10.1200/JCO.2005.11. 007 1:CAS:528:DC%2BD2MXht1WrsrzK (Pubitemid 46291811)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.30
, pp. 7483-7490
-
-
Knoop, A.S.1
Knudsen, H.2
Balslev, E.3
Rasmussen, B.B.4
Overgaard, J.5
Nielsen, K.V.6
Schonau, A.7
Gunnarsdottir, K.8
Olsen, K.E.9
Mouridsen, H.10
Ejlertsen, B.11
-
14
-
-
54849441046
-
Type 1 receptor tyrosine kinase profiles identify patients with enhanced benefit from anthracyclines in the BR9601 adjuvant breast cancer chemotherapy trial
-
18768436 10.1200/JCO.2007.14.6597 1:CAS:528:DC%2BD1cXhsVGhsrrE
-
JM Bartlett A Munro DA Cameron J Thomas R Prescott CJ Twelves 2008 Type 1 receptor tyrosine kinase profiles identify patients with enhanced benefit from anthracyclines in the BR9601 adjuvant breast cancer chemotherapy trial J Clin Oncol 26 5027 5035 18768436 10.1200/JCO.2007.14.6597 1:CAS:528: DC%2BD1cXhsVGhsrrE
-
(2008)
J Clin Oncol
, vol.26
, pp. 5027-5035
-
-
Bartlett, J.M.1
Munro, A.2
Cameron, D.A.3
Thomas, J.4
Prescott, R.5
Twelves, C.J.6
-
15
-
-
65549158566
-
Topoisomerase II alpha and responsiveness of breast cancer to adjuvant chemotherapy
-
19401546 10.1093/jnci/djp067
-
FP O'Malley S Chia D Tu LE Shepherd MN Levine VH Bramwell IL Andrulis KI Pritchard 2009 Topoisomerase II alpha and responsiveness of breast cancer to adjuvant chemotherapy J Natl Cancer Inst 101 644 650 19401546 10.1093/jnci/djp067
-
(2009)
J Natl Cancer Inst
, vol.101
, pp. 644-650
-
-
O'Malley, F.P.1
Chia, S.2
Tu, D.3
Shepherd, L.E.4
Levine, M.N.5
Bramwell, V.H.6
Andrulis, I.L.7
Pritchard, K.I.8
-
16
-
-
76949095602
-
Phase III randomized trial comparing doxorubicin and cyclophosphamide followed by docetaxel (AC → T) with doxorubicin and cyclophosphamide followed by docetaxel and trastuzumab (AC → TH) with docetaxel, carboplatin and trastuzumab (TCH) in Her2neu positive early breast cancer patients: BCIRG 006 study
-
D Slamon W Eiermann N Robert, et al. 2009 Phase III randomized trial comparing doxorubicin and cyclophosphamide followed by docetaxel (AC → T) with doxorubicin and cyclophosphamide followed by docetaxel and trastuzumab (AC → TH) with docetaxel, carboplatin and trastuzumab (TCH) in Her2neu positive early breast cancer patients: BCIRG 006 study Cancer Res 69 500S
-
(2009)
Cancer Res
, vol.69
-
-
Slamon, D.1
Eiermann, W.2
Robert, N.3
-
17
-
-
77349093380
-
A meta-analysis of phase III trials evaluating the predictive value of HER2 and topoisomerase II alpha in early breast cancer patients treated with CMF or anthracycline-based adjuvant therapy
-
A Di Leo J Isola F Piette, et al. 2009 A meta-analysis of phase III trials evaluating the predictive value of HER2 and topoisomerase II alpha in early breast cancer patients treated with CMF or anthracycline-based adjuvant therapy Cancer Res 69 99S
-
(2009)
Cancer Res
, vol.69
-
-
Di Leo, A.1
Isola, J.2
Piette, F.3
-
18
-
-
0017345746
-
Assessment of response to therapy in advanced breast cancer. A project of the programme on clinical oncology of the International Union Against Cancer, Geneva, Switzerland
-
JL Hayward PP Carbone JC Heuson S Kumaoka A Segaloff RD Rubens 1977 Assessment of response to therapy in advanced breast cancer: a project of the Programme on Clinical Oncology of the International Union Against Cancer, Geneva, Switzerland Cancer 39 1289 1294 912660 10.1002/1097-0142(197703)39: 3<1289::AID-CNCR2820390340>3.0.CO;2-F 1:STN:280:DyaE1c%2Fit1eksg%3D%3D (Pubitemid 8081207)
-
(1977)
Cancer
, vol.39
, Issue.3
, pp. 1289-1294
-
-
Hayward, J.L.1
Carbone, P.P.2
Heuson, J.C.3
-
19
-
-
33744991353
-
Topoisomerase IIα gene amplification and response to anthracycline-containing adjuvant chemotherapy in breast cancer
-
DOI 10.1200/JCO.2006.05.9113
-
AU Buzdar 2006 Topoisomerase IIalpha gene amplification and response to anthracycline-containing adjuvant chemotherapy in breast cancer J Clin Oncol 24 2409 2411 16682721 10.1200/JCO.2006.05.9113 (Pubitemid 46630613)
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.16
, pp. 2409-2411
-
-
Buzdar, A.U.1
|