Local anesthetics inhibit kinesin motility and microtentacle protrusions in human epithelial and breast tumor cells

Breast Cancer Research and Treatment

Volumn 129, Issue 3, 2011, Pages 691-701

  Yoon, Jennifer R ^a   Whipple, Rebecca A ^a   Balzer, Eric M ^a,b   Cho, Edward H ^a,b   Matrone, Michael A ^a,b   Peckham, Michelle ^c   Martin, Stuart S ^a,d  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b Programs in Molecular and Cellular Biology Oncology and Toxicology   (United States)

^c UNIVERSITY OF LEEDS   (United Kingdom)

^d Bressler Bldg ^*  (United States)

Author keywords

Breast cancer; Glu tubulin; Kinesin; Metastasis; Microtentacles; Tetracaine

Indexed keywords

KINESIN; LIDOCAINE; TETRACAINE; VIMENTIN;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BREAST EPITHELIUM; BREAST TUMOR; CELL ADHESION; CELL AGGREGATION; CELL ASSAY; CELL COUNT; CELL MOTILITY; CELL STRUCTURE; CELL VIABILITY; CONTROLLED STUDY; DRUG CYTOTOXICITY; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; INTRACELLULAR SPACE; MICROFILAMENT; MICROTENTACLE; MICROTUBULE; PRIORITY JOURNAL; TUMOR CELL;

ANESTHETICS, LOCAL; BREAST NEOPLASMS; CELL ADHESION; CELL LINE, TUMOR; CELL MOVEMENT; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; EPITHELIAL CELLS; FEMALE; GREEN FLUORESCENT PROTEINS; HUMANS; KINESIN; LIDOCAINE; MAMMARY GLANDS, HUMAN; TETRACAINE; TUBULIN; VIMENTIN;

EID: 80052580680     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-010-1239-7     Document Type: Article

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