-
2
-
-
77952939825
-
-
str
-
H.P Rang, M.M. Dale, J.M. Riter, P.T. Moore, Farmakologija, peto izdanje, Data status, Beograd, 2005, str. 550-560.
-
(2005)
Farmakologija, Peto Izdanje, Data Status, Beograd
, pp. 550-560
-
-
Rang, H.P.1
Dale, M.M.2
Riter, J.M.3
Moore, P.T.4
-
5
-
-
80052582837
-
Treatment of tremor using compounds that depress calcium currents in thalamic and other central nervous system neurons
-
(Univ Leland Stanford Junior [US])
-
D.A. Prince, Treatment of tremor using compounds that depress calcium currents in thalamic and other central nervous system neurons, (Univ Leland Stanford Junior [US]), U.S. Patent 4,981,867, 1991.
-
(1991)
U.S. Patent 4,981
, pp. 867
-
-
Prince, D.A.1
-
6
-
-
80052561306
-
-
th ed., Georg Thieme Verlag, Stuttgart
-
th ed., Georg Thieme Verlag, Stuttgart, 2001, p. 1834.
-
(2001)
Pharmaceutical Substances: Syntheses, Patents, Applications
, pp. 1834
-
-
Kleemann, A.1
Engel, J.2
-
7
-
-
69949164182
-
The design and optimization of a series of 2-(pyridin-2-yl)-1H-benzimidazole compounds as allosteric glucokinase activators
-
K. Takahashi, N. Hashimoto, C. Nakama, K. Kamata, K. Sasaki, R. Yoshimoto, S. Ohyama, H. Hosaka, H. Maruki, Y. Nagata, J.-I. Eiki, T. Nishimura, The design and optimization of a series of 2-(pyridin-2-yl)-1H-benzimidazole compounds as allosteric glucokinase activators, Bioorg. Med. Chem. 17 (2009) 7042-7051.
-
(2009)
Bioorg. Med. Chem
, vol.17
, pp. 7042-7051
-
-
Takahashi, K.1
Hashimoto, N.2
Nakama, C.3
Kamata, K.4
Sasaki, K.5
Yoshimoto, R.6
Ohyama, S.7
Hosaka, H.8
Maruki, H.9
Nagata, Y.10
Eiki, J.-I.11
Nishimura, T.12
-
8
-
-
18644362147
-
Succinimide hydroxamic acids as potent inhibitors of histone deacetylase (HDAC)
-
M.L. Curtin, R.B. Garland, H.R. Heyman, R.R. Frey, M.R. Michaelides, J. Li, L.J. Pease, K.B. Glaser, P.A. Marcotte, S.K. Davidsen, Succinimide hydroxamic acids as potent inhibitors of histone deacetylase (HDAC), Bioorg. Med. Chem. Lett. 12 (2002) 2919-2923.
-
(2002)
Bioorg. Med. Chem. Lett
, vol.12
, pp. 2919-2923
-
-
Curtin, M.L.1
Garland, R.B.2
Heyman, H.R.3
Frey, R.R.M.R.4
Michaelides, L.J.5
Pease, L.J.6
Glaser, K.B.7
Marcotte, P.A.8
Davidsen, S.K.9
-
9
-
-
80052573181
-
Synthesis and biological activity studies of new N-substituted (phosphinothiadiazolyl)amino]succinimides
-
Y.I. Hubsky, O.V. Velchynska, Synthesis and biological activity studies of new N-substituted (phosphinothiadiazolyl)amino]succinimides, Med. Khim. 10 (2008) 5-11.
-
(2008)
Med. Khim
, vol.10
, pp. 5-11
-
-
Hubsky, Y.I.1
Velchynska, O.V.2
-
10
-
-
21144452500
-
Synthesis and antimicrobial activity of some of new 1,1,3-trisubstituted cyclobutane-containing thiazoles, succinimide and phthalimide derivatives
-
M. Ahmedzade, A. Cukurovali, M. Koparir, Synthesis and antimicrobial activity of some of new 1,1,3-trisubstituted cyclobutane-containing thiazoles, succinimide and phthalimide derivatives, J. Chem. Soc. Pakistan 25 (2003) 51-55.
-
(2003)
J. Chem. Soc. Pakistan
, vol.25
, pp. 51-55
-
-
Ahmedzade, M.1
Cukurovali, A.2
Koparir, M.3
-
11
-
-
27144534269
-
Synthesis and antimicrobial activity of some succinimides
-
N.P. Shetgiri, B.K. Nayak, Synthesis and antimicrobial activity of some succinimides, Indian J. Chem. B 44B (2005) 1933-1936.
-
(2005)
Indian J. Chem. B
, vol.44 B
, pp. 1933-1936
-
-
Shetgiri, N.P.1
Nayak, B.K.2
-
12
-
-
70450223713
-
Synthesis and antimicrobial activity of some new N-acyl substituted phenothiazines
-
T.N. Bansode, J.V. Shelke, V.G. Dongre, Synthesis and antimicrobial activity of some new N-acyl substituted phenothiazines, Eur. J. Med. Chem. 44 (2009) 5094-5098.
-
(2009)
Eur. J. Med. Chem
, vol.44
, pp. 5094-5098
-
-
Bansode, T.N.1
Shelke, J.V.2
Dongre, V.G.3
-
13
-
-
0000980734
-
The magnetic anisotropy and electron distribution in succinimide
-
R. Mason, The magnetic anisotropy and electron distribution in succinimide, Acta Cryst. 14 (1961) 720-724.
-
(1961)
Acta Cryst
, vol.14
, pp. 720-724
-
-
Mason, R.1
-
14
-
-
0010649350
-
2N
-
R. Mason, The chrystal and molecular structure of succinimide C4H5O2N, Acta Cryst. 9 (1956) 405-410.
-
(1956)
Acta Cryst
, vol.9
, pp. 405-410
-
-
Mason, R.1
-
15
-
-
61749083865
-
Flexibility of the saturated five-membered ring in 2,5-pyrrolidinedione (succinimide): Electron diffraction and quantum-chemical studies with use of vibrational spectroscopy data
-
N. Vogt, L.S. Khaikin, O.E. Grikina, N.M. Karasev, J. Vogt, L.V. Vilkov, Flexibility of the saturated five-membered ring in 2,5-pyrrolidinedione (succinimide): electron diffraction and quantum-chemical studies with use of vibrational spectroscopy data, J. Phys. Chem. A 113 (2009) 931-937.
-
(2009)
J. Phys. Chem. A
, vol.113
, pp. 931-937
-
-
Vogt, N.1
Khaikin, L.S.2
Grikina, O.E.3
Karasev, N.M.4
Vogt, J.5
Vilkov, L.V.6
-
16
-
-
30744461597
-
Three isomeric N-(nitrophenyl)succinimides: Isolated molecules, hydrogen-bonded sheets and a hydrogen-bonded three-dimensional framework
-
C. Glidewell, J.N. Low, J.M.S. Skakle, J.L. Wardell, Three isomeric N-(nitrophenyl)succinimides: isolated molecules, hydrogen-bonded sheets and a hydrogen-bonded three-dimensional framework, Acta Cryst. C 61 (2005), 216-220.
-
(2005)
Acta Cryst. C
, vol.61
, pp. 216-220
-
-
Glidewell, C.1
Low, J.N.2
Skakle, J.M.S.3
Wardell, J.L.4
-
17
-
-
0040647681
-
Electronic conditions for anticonvulsant activity of diphenylsuccinimides: Crystal and molecular structure of 1,1-diphenyl-N-(2-pyridyl)-succinimide
-
J. Karolak-Wojciechowska, M. Blaszczyk, W. Kwiatkowsky, J. Obniska, A. Zejc, Electronic conditions for anticonvulsant activity of diphenylsuccinimides: crystal and molecular structure of 1,1-diphenyl-N-(2-pyridyl)-succinimide, J. Chem. Cryst. 27 (1997) 297-301.
-
(1997)
J. Chem. Cryst
, vol.27
, pp. 297-301
-
-
Karolak-Wojciechowska, J.1
Blaszczyk, M.2
Kwiatkowsky, W.3
Obniska, J.4
Zejc, A.5
-
19
-
-
80052604103
-
Organska hemija: Struktura i funkcija, četvrto izdanje
-
K. P. C. Vollhardt, N. E. Schore, Organska hemija: struktura i funkcija, četvrto izdanje, Data status, Beograd, 2003, str. 574.
-
(2003)
Data Status, Beograd
, pp. 574
-
-
Vollhardt, K.P.C.1
Schore, N.E.2
-
20
-
-
3142580903
-
Synthesis of 3,3-diarylpyrrolidines from diaryl ketones
-
A.R. Katritzky, S.K. Nair, R.M. Witek, S.M. Hutchins, Synthesis of 3,3-diarylpyrrolidines from diaryl ketones, ARKIVOC V (2003) 9-18.
-
(2003)
ARKIVOC V
, pp. 9-18
-
-
Katritzky, A.R.1
Nair, S.K.2
Witek, R.M.3
Hutchins, S.M.4
-
21
-
-
13544251668
-
The synthesis and reactions of some N-acyl-N-aryliminium ions
-
S. Brunton, K. Jones, The synthesis and reactions of some N-acyl-N-aryliminium ions, ARKIVOC III (2000) 292-303.
-
(2000)
ARKIVOC III
, pp. 292-303
-
-
Brunton, S.1
Jones, K.2
-
23
-
-
0001702527
-
Condensation reactions. II. Alkylidene cyanoacetic and malonic esters
-
A.C. Cope, C.M. Hoffman, C. Wyckoff, E. Hardenbergh, Condensation reactions. II. Alkylidene cyanoacetic and malonic esters, J. Am. Chem. Soc. 63 (1941) 3452-3456.
-
(1941)
J. Am. Chem. Soc
, vol.63
, pp. 3452-3456
-
-
Cope, A.C.1
Hoffman, C.M.2
Wyckoff, C.3
Hardenbergh, E.4
-
25
-
-
0001488108
-
1-α-phenylsuccinimides
-
C.A. Miller, L.M. Long, Anticonvulsants. I. An investigation of N-R-α-R1-α-phenylsuccinimides, J. Am. Chem. Soc. 73 (1951) 4895-4898.
-
(1951)
J. Am. Chem. Soc
, vol.73
, pp. 4895-4898
-
-
Miller, C.A.1
Long, L.M.2
-
26
-
-
33947458670
-
Anticonvulsants. III. A study of N,α,β-alkylsuccinimides
-
C.A. Miller, L.M. Long, Anticonvulsants. III. A study of N,α,β-alkylsuccinimides, J. Am. Chem. Soc. 75 (1953) 373-375.
-
(1953)
J. Am. Chem. Soc
, vol.75
, pp. 373-375
-
-
Miller, C.A.1
Long, L.M.2
-
27
-
-
32944467278
-
Properties of antiepileptic drugs in the treatment of idiopathic generalized epilepsies
-
P. N. Patsalos, Properties of antiepileptic drugs in the treatment of idiopathic generalized epilepsies, Epilepsia 46 (2005) 140-148.
-
(2005)
Epilepsia
, vol.46
, pp. 140-148
-
-
Patsalos, P.N.1
-
28
-
-
24944555997
-
-
th ed., Volume 6, Nervous System Agents, Wiley-Interscience
-
th ed., Volume 6, Nervous System Agents, Wiley-Interscience, 2003, pp. 283-289.
-
(2003)
Burger's Medicinal Chemistry and Drug Discovery
, pp. 283-289
-
-
Abraham, D.1
-
29
-
-
80052559579
-
-
AHFS Drug Information, G.K. McEvoy (Ed.), Md: American Society of Health-System Pharmacists
-
AHFS Drug Information, G.K. McEvoy (Ed.), Bethesda, Md: American Society of Health-System Pharmacists, 2003, pp. 2115-2117.
-
(2003)
Bethesda
, pp. 2115-2117
-
-
-
30
-
-
80052556732
-
-
http://drugbank.ca/drugs/DB00593 452
-
-
-
-
31
-
-
80052600101
-
-
th ed., Lippincott Williams & Wilkins, Philadelphia, PA
-
th ed., Lippincott Williams & Wilkins, Philadelphia, PA, 2008, pp. 542-543.
-
(2008)
Foye's Principles of Medicinal Chemistry
, pp. 542-543
-
-
Lemke, T.L.1
Williams, D.A.2
Roche, V.F.3
Zito, S.W.4
-
32
-
-
80052560727
-
-
National Library of Medicine
-
National Library of Medicine, http:////chem.sis.nlm.nih.gov
-
-
-
-
33
-
-
0014954884
-
Diphenylhydantoin and diazepam: Molecular structure similarities and steric basis of anticonvulsant activity
-
A. Camerman, N. Camerman, Diphenylhydantoin and diazepam: molecular structure similarities and steric basis of anticonvulsant activity, Science 168 (1970) 1457-1458.
-
(1970)
Science
, vol.168
, pp. 1457-1458
-
-
Camerman, A.1
Camerman, N.2
-
34
-
-
0001666825
-
The stereochemical basis of anticonvulsant drug action
-
I. The crystal and molecular structure of diphenylhydantoin, a noncentrosymmetric structure solved by centric symbolic addition
-
A. Camerman, N. Camerman, The stereochemical basis of anticonvulsant drug action. I. The crystal and molecular structure of diphenylhydantoin, a noncentrosymmetric structure solved by centric symbolic addition, Acta. Cryst. Sect. B 27 (1971) 2205-2211.
-
(1971)
Acta. Cryst. Sect. B
, vol.27
, pp. 2205-2211
-
-
Camerman, A.1
Camerman, N.2
-
35
-
-
0015503526
-
Stereochemical basis of anticonvulsant drug action. II. Molecular structure of diazepam
-
A. Camerman, N. Camerman, Stereochemical basis of anticonvulsant drug action. II. Molecular structure of diazepam, J. Am. Chem. Soc. 94 (1972) 268-272.
-
(1972)
J. Am. Chem. Soc
, vol.94
, pp. 268-272
-
-
Camerman, A.1
Camerman, N.2
-
36
-
-
0009111688
-
-
Raven Press, New York
-
G.H. Glaser, J.K. Penry, D.M. Woodbury, Antiepileptic Drugs: Mechanisms of Action, Raven Press, New York, 1980, pp. 223-231.
-
(1980)
Antiepileptic Drugs: Mechanisms of Action
, pp. 223-231
-
-
Glaser, G.H.1
Penry, J.K.2
Woodbury, D.M.3
-
37
-
-
0025084679
-
Sodium channel binding and anticonvulsant activities of hydantoins containing conformationally constrained 5phenyl substituents
-
W.J. Brouillette, G.B. Brown, T.M. DeLorey, G. Liang, Sodium channel binding and anticonvulsant activities of hydantoins containing conformationally constrained 5phenyl substituents, J. Pharm. Sci. 79 (1990) 871-874.
-
(1990)
J. Pharm. Sci
, vol.79
, pp. 871-874
-
-
Brouillette, W.J.1
Brown, G.B.2
Delorey, T.M.3
Liang, G.4
-
38
-
-
0023691172
-
Anticonvulsant activities of phenylsubstituted bicyclic 2,4-oxazolidinediones and monocyclic models. Comparison with binding to the neuronal voltage-dependent sodium channel
-
W.J. Brouillette, G.B. Brown, T.M. DeLorey, S.S. Shirali, G.L. Grunewald, Anticonvulsant activities of phenylsubstituted bicyclic 2,4-oxazolidinediones and monocyclic models. Comparison with binding to the neuronal voltage-dependent sodium channel, J. Med. Chem. 31 (1988) 2218-2221.
-
(1988)
J. Med. Chem
, vol.31
, pp. 2218-2221
-
-
Brouillette, W.J.1
Brown, G.B.2
Delorey, T.M.3
Shirali, S.S.4
Grunewald, G.L.5
-
39
-
-
0028028227
-
Bicyclic hydantoins with a bridgehead nitrogen. Comparison of anticonvulsant activities with binding to the neuronal voltage-dependent sodium channel
-
W. J. Brouillette, V. P. Jestkov, M. L. Brown, M.S. Akhar, T. M. DeLorey, G. B. Brown, Bicyclic hydantoins with a bridgehead nitrogen. Comparison of anticonvulsant activities with binding to the neuronal voltage-dependent sodium channel, J. Med. Chem. 37 (1994) 3289-3293.
-
(1994)
J. Med. Chem
, vol.37
, pp. 3289-3293
-
-
Brouillette, W.J.1
Jestkov, V.P.2
Brown, M.L.3
Akhar, M.S.4
Delorey, T.M.5
Brown, G.B.6
-
40
-
-
0022472943
-
Conformational analysis of clinically active anticonvulsant drugs
-
M.G. Wong, J.A. Defina, P.R. Andrews, Conformational analysis of clinically active anticonvulsant drugs, J. Med. Chem. 29 (1986) 562-572.
-
(1986)
J. Med. Chem
, vol.29
, pp. 562-572
-
-
Wong, M.G.1
Defina, J.A.2
Andrews, P.R.3
-
41
-
-
0015978013
-
Quinazolines and 1,4-benzodiazepines. 64. Comparison of the stereochemistry of diazepam with that of close analogs with marginal biological activity
-
L.H. Sternbach, F.D. Sancilio, J.F. Blount, Quinazolines and 1,4-benzodiazepines. 64. Comparison of the stereochemistry of diazepam with that of close analogs with marginal biological activity, J. Med. Chem. 17 (1974) 374-377.
-
(1974)
J. Med. Chem
, vol.17
, pp. 374-377
-
-
Sternbach, L.H.1
Sancilio, F.D.2
Blount, J.F.3
-
42
-
-
0030938869
-
Design of dual acting anticonvulsant-antimuscarinic succinimide and hydantoin derivatives
-
R.L. Hudkins, D.L. DeHaven-Hudkins, P. Doukas, Design of dual acting anticonvulsant-antimuscarinic succinimide and hydantoin derivatives, Bioorg. Med. Chem. Lett. 7 (1997) 979-984.
-
(1997)
Bioorg. Med. Chem. Lett
, vol.7
, pp. 979-984
-
-
Hudkins, R.L.1
Dehaven-Hudkins, D.L.2
Doukas, P.3
-
43
-
-
0021332122
-
Structure-activity relationships of phenytoin-like anticonvulsant drugs
-
J.H. Poupaert, D. Vandervorst, P. Guiot, M.M.M. Moustafa, P. Dumont, Structure-activity relationships of phenytoin-like anticonvulsant drugs, J. Med. Chem. 27 (1984) 76-78.
-
(1984)
J. Med. Chem
, vol.27
, pp. 76-78
-
-
Poupaert, J.H.1
Vandervorst, D.2
Guiot, P.3
Moustafa, M.M.M.4
Dumont, P.5
-
44
-
-
0016607882
-
Anticonvulsants. 5. Derivatives of 5-ethyl-5-phenylhydantoin and 5,5-diphenylhydantoin
-
J.A. Vida, M.H. Odea, C. M. Samour, J. F. Reinhard, Anticonvulsants. 5. Derivatives of 5-ethyl-5-phenylhydantoin and 5,5-diphenylhydantoin, J. Med. Chem. 18 (1975) 383-385.
-
(1975)
J. Med. Chem
, vol.18
, pp. 383-385
-
-
Vida, J.A.1
Odea, M.H.2
Samour, C.M.3
Reinhard, J.F.4
-
45
-
-
34249681314
-
Solvent effects on the structure-activity relationship of pharmacological active 3-substituted-5,5-diphenylhydantoins
-
N. Banjac, G. Ušćumlić, N. Valentić, D. Mijin, Solvent effects on the structure-activity relationship of pharmacological active 3-substituted-5,5-diphenylhydantoins, J. Solution Chem. 36 (2007) 869-878
-
(2007)
J. Solution Chem
, vol.36
, pp. 869-878
-
-
Banjac, N.1
Ušćumlić, G.2
Valentić, N.3
Mijin, D.4
-
46
-
-
62549135656
-
Solvent effects on the structure-activity relationship of phenytoin-like anticonvulsant drugs
-
N. Trišović, N. Valentić, N. Banjac, G. Ušćumlić, Solvent effects on the structure-activity relationship of phenytoin-like anticonvulsant drugs, J. Solution. Chem. 38 (2009) 199-208.
-
(2009)
J. Solution. Chem
, vol.38
, pp. 199-208
-
-
Trišović, N.1
Valentić, N.2
Banjac, N.3
Ušćumlić, G.4
-
48
-
-
79953807997
-
Reversed-phase TLC and HPLC retention data in correlation studies with in silico molecular descriptors and druglikeness properties of newly synthesized anticonvulsant succinimide derivatives
-
N. Perišić-Janjić, R. Kaliszan, P. Wiczling, N. Milošević, G. Ušćumlić, N. Banjac, Reversed-phase TLC and HPLC retention data in correlation studies with in silico molecular descriptors and druglikeness properties of newly synthesized anticonvulsant succinimide derivatives, Mol. Pharmaceutics 8 (2011) 555-563.
-
(2011)
Mol. Pharmaceutics
, vol.8
, pp. 555-563
-
-
Perišić-Janjić, N.1
Kaliszan, R.2
Wiczling, P.3
Milošević, N.4
Ušćumlić, G.5
Banjac, N.6
|